Rosiglitazone Suppliers USA
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Product | Description | |
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Rosiglitazone maleate (BRL 49653, HSDB 7555, TDZ 01, Rosiglitazone XR, Avandia, PPAR Agonist X, PPARg Agonist IX) Quick inquiry Where to buy Suppliers range | Same activities as rosaglitazone but different formulation. Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and vascular function. Enhances proliferation of endogenous neural progenitor cells (NPCs). Anti-inflammatory compound. Has controversial therapeutic effects on the cardiovascular system. Promotes adipocyte differentiation of mesenchymal stem cells (MSCs). Group: Biochemicals. Grades: Highly Purified. CAS No. 155141-29-0. Pack Sizes: 25mg, 100mg, 1g. Molecular Formula: C18H19N3O3S. C4H4O4. US Biological Life Sciences. | Worldwide |
Rosiglitazone Quick inquiry Where to buy Suppliers range | Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and vascular function. Enhances proliferation of endogenous neural progenitor cells (NPCs). Anti-inflammatory compound. Has controversial therapeutic effects on the cardiovascular system. Group: Biochemicals. Grades: Highly Purified. CAS No. 122320-73-4. Pack Sizes: 25mg, 100mg, 1g. Molecular Formula: C??H??N?O?S. US Biological Life Sciences. | Worldwide |
Rosiglitazone Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy; Pharmaceutical Toxicology. Alternative Names: 5- [ [4- [2- [N-Methyl-N- (2-pyridyl) amino] ethoxy] phenyl] methyl] thiazolidine-2, 4-dione, Rosvel,2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-, Rosiglitazone, Rosiglizole, Rezult, 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione, BRL 49653, 5-[4-[2- (N-Methyl-N- (2-pyridyl) amino) ethoxy]benzyl]thiazolidine-2, 4-dione, TDZ 01. CAS No. 122320-73-4. Pack Sizes: 10MG. IUPAC Name: 5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione. Molecular formula: C18H19N3O3S. Mole weight: 357.43. Catalog: APS122320734. Assay: ≥98% (HPLC); ≥98% (HPLC). SMILES: CN (CCOc1ccc (CC2SC (=O)NC2=O)cc1)c3ccccn3. Format: Neat. Shipping: Room Temperature. Linear Formula: C18H19N3O3S. | |
Rosiglitazone Quick inquiry Where to buy Suppliers range | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C18H19N3O3S. CAS No. 122320-73-4. Prepack ID 48650295-1g. Molecular Weight 357.43. See USA prepack pricing. | |
Rosiglitazone-d3 Quick inquiry Where to buy Suppliers range | Labeled Rosiglitazone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Rosiglitazone hydrochloride Quick inquiry Where to buy Suppliers range | Rosiglitazone HCl is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells. Synonyms: BRL-49653 HCl; BRL 49653 HCl; BRL49653 HCl. Grades: >98%. CAS No. 302543-62-0. Molecular formula: C18H19N3O3S.HCl. Mole weight: 393.89. | |
Rosiglitazone hydrochloride Quick inquiry Where to buy Suppliers range | Rosiglitazone (BRL 49653) hydrochloride is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM). Rosiglitazone hydrochloride is a TRPC5 activator (EC50: 30 μM) and TRPM3 inhibitor. Rosiglitazone hydrochloride can be used in the research of obesity and diabetes, senescence, ovarian cancer. Group: Biobased Products. Alternative Names: 5-[4-[2-[N-Methyl-N- (pyridinyl) amino]ethoxy]benzyl]thiazolidine-2,4-dione hydrochloride. Grades: 98%. CAS No. 302543-62-0. Product ID: BBC302543620. Molecular formula: C18H19N3O3S.HCl. Mole weight: 393.89. IUPAC Name: 5-[[4-[2-[Methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydrochloride. Appearance: Powder. SMILES: CN (CCOC1=CC=C (C=C1)CC2C (=O)NC (=O)S2)C3=CC=CC=N3. Cl. | |
Rosiglitazone Impurity (5-(4-Fluorobenzyl)-2,4-thiazolidinedione) Quick inquiry Where to buy Suppliers range | A metabolite of Pioglitazone which is a metabolite of Pioglitazone, a prescription drug of the thiazolidinedione (TZD) class. Synonyms: 5-(4-Fluorobenzyl)-2,4-thiazolidinedione. Grades: > 95%. CAS No. 291536-42-0. Molecular formula: C10H8FNO2S. Mole weight: 225.24. | |
Rosiglitazone Impurity (5-[4-N-(2-Pyridylamino)ethoxy]benzylidene] thiazolidine-2,4-dione) Quick inquiry Where to buy Suppliers range | An impurity of Rosiglitazone.Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. Synonyms: 5-[4-[N- (2-Pyridylamino) ethoxy]benzylidene]thiazolidine-2, 4-dione. Grades: > 95%. CAS No. 643764-88-9. Molecular formula: C17H15N3O3S. Mole weight: 341.39. | |
Rosiglitazone maleate Quick inquiry Where to buy Suppliers range | Rosiglitazone maleate. Group: Biochemicals. Alternative Names: 5-[[4-[2- (Methyl-2-pyridinylamino) ethoxy]phenyl]methyl]-2, 4-thiazolidinedione (2Z)-2-butenedioate. Grades: Highly Purified. CAS No. 155141-29-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C22H23N3O7S. US Biological Life Sciences. | Worldwide |
Rosiglitazone maleate Quick inquiry Where to buy Suppliers range | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H23N3O7S. CAS No. 155141-29-0. Prepack ID 46249044-1g. Molecular Weight 473.5. See USA prepack pricing. | |
Rosiglitazone Maleate Quick inquiry Where to buy Suppliers range | Rosiglitazone Maleate. Uses: For analytical and research use. Group: Pharma & Vet Compounds & Metabolites; Pharma & Vet Compounds & Metabolites; API Standards; Pharmaceutical Toxicology. Alternative Names: 5-[[4-[2- (N-Methyl-N-2-pyridylamino) ethoxy]phenyl]methyl]thiazolidine-2, 4-dione maleate, SB236833,2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-, (2Z)-2-butenedioate (1:1), BRL 49653C, Rosiglitazone maleate, BRL-49653C, BRL 49653C, SB237216, 2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-, (Z)-2-butenedioate (1:1), Avandia, SB214521. CAS No. 155141-29-0. IUPAC Name: (Z)-but-2-enedioic acid;5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione. Molecular formula: C18H19N3O3S.C4H4O4. Mole weight: 473.50. Catalog: APS155141290. SMILES: CN (CCOc1ccc (CC2SC (=O)NC2=O)cc1)c3ccccn3. OC (=O)\C=C/C (=O)O. Format: Neat. | |
Rosiglitazone Maleate (5-[[4-[2- (Methyl-2-pyridinylamino) ethoxy]phenyl]methyl]-2, 4-thiazolidinedione Maleate, BRL-49653c, Avandia) Quick inquiry Where to buy Suppliers range | Insulin sensitizer; binds to peroxisome proliferator activated receptor gamma (PPAR- g). Group: Biochemicals. Alternative Names: 5-[[4-[2- (Methyl-2-pyridinylamino) ethoxy]phenyl]methyl]-2, 4-thiazolidinedione Maleate; BRL-49653c; Avandia. Grades: Highly Purified. CAS No. 155141-29-0. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Rosiglitazone potassium salt Quick inquiry Where to buy Suppliers range | Rosiglitazone is an agonist of peroxisome proliferator-activated receptor γ (PPARγ) that binds to PPARγ and sensitizes its response to insulin. It has been indicated for the treatment of type 2 diabetes, however, its application was restricted for increasing the risk of heart failure. Synonyms: 5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidin-3-ide-2,4-dione potassium salt. Grades: ≥98%. CAS No. 316371-84-3. Molecular formula: C18H18N3O3S·K. Mole weight: 395.5. | |
5-Benzyloxy Rosiglitazone-d4 Quick inquiry Where to buy Suppliers range | Rosiglitazone derivative. Thiazolidinedione derivative, with antidiabetic properties. Group: Biochemicals. Alternative Names: 5-{4- [2- [ (5-Benzyloxypyridin-2-yl) methylamino] ethoxy] benzyl}thiazolidine-2, 4-dione-d4; 5- [ [3- [2- [Methyl [5- (phenylmethoxy) -2-pyridinyl] amino] ethoxy] phenyl] methyl] -2, 4-thiazolidinedione-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
5-Hydroxy rosiglitazone Quick inquiry Where to buy Suppliers range | An impurity of Rosiglitazone.Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. Synonyms: 5-[[4-[2-[ (5-Hydroxy-2-pyridinyl) methylamino]ethoxy]phenyl]methyl]-2, 4-thiazolidinedione. Grades: > 95%. CAS No. 257883-22-0. Molecular formula: C18H19N3O4S. Mole weight: 373.43. | |
5-Hydroxy Rosiglitazone (5- [ [4- [2- [ (5-Hydroxy-2-pyridinyl) methylamino] ethoxy] phenyl] methyl] -2, 4-thiazolidinedione) Quick inquiry Where to buy Suppliers range | A metabolite of Rosiglitazone. Group: Biochemicals. Alternative Names: 5- [ [4- [2- [ (5-Hydroxy-2-pyridinyl) methylamino] ethoxy] phenyl] methyl] -2, 4-thiazolidinedione. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
(5-Hydroxy rosiglitazone)-b-D-glucuronide Quick inquiry Where to buy Suppliers range | (5-Hydroxy rosiglitazone)-b-D-glucuronide is a biochemical compound used as a metabolite marker in diabetes research. Specifically, it is associated with the study of type 2 diabetes mellitus as a breakdown product of rosiglitazone, an antidiabetic medication. Synonyms: 6-[6-({2-[4-Dioxo-thiazolindin-5-yl-methyl)-phenoxy]ethyl}-methyl-amino)-pyridin-3-yloxy]-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid. CAS No. 288853-59-8. Molecular formula: C24H27N3O10S. Mole weight: 549.55. | |
5-Hydroxy Rosiglitazone-d4 Quick inquiry Where to buy Suppliers range | A labeled metabolite of Rosiglitazone. Group: Biochemicals. Alternative Names: 5-[[4-[2-[ (5-Hydroxy-2-pyridinyl) methylamino]ethoxy-d4]phenylmethyl]-2, 4-thiazolidinedione. Grades: Highly Purified. CAS No. 1246817-46-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
5-Hydroxy rosiglitazone sulfate Quick inquiry Where to buy Suppliers range | 5-Hydroxy rosiglitazone sulfate. Group: Biochemicals. Alternative Names: 5- [ [4- [2- [Methyl [5- (sulfooxy) -2-pyridinyl] amino] ethoxy] phenyl] methyl] -2, 4-thiazolidinedione. Grades: Highly Purified. CAS No. 288853-63-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C18H19N3O7S2. US Biological Life Sciences. | Worldwide |
5-Hydroxy rosiglitazone sulphate potassium salt Quick inquiry Where to buy Suppliers range | An impurity of Rosiglitazone.Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. Grades: > 95%. Molecular formula: C18H18N3O7S2.K. Mole weight: 491.59. | |
N-Desmethyl rosiglitazone Quick inquiry Where to buy Suppliers range | N-Desmethyl rosiglitazone. Group: Biochemicals. Alternative Names: 5-[[4-[2- (2-Pyridinylamino) ethoxy]phenyl]methyl]-2, 4-thiazolidinedione; SB 237216. Grades: Highly Purified. CAS No. 257892-31-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C17H17N3O3S. US Biological Life Sciences. | Worldwide |
N-Desmethyl rosiglitazone Quick inquiry Where to buy Suppliers range | An impurity of Rosiglitazone.Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. Synonyms: 5-[[4-[2-(2-Pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione; SB 237216. Grades: > 95%. CAS No. 257892-31-2. Molecular formula: C17H17N3O3S. Mole weight: 343.41. | |
N-Desmethyl Rosiglitazone. Quick inquiry Where to buy Suppliers range | A metabolite of Rosiglitazone. Group: Biochemicals. Alternative Names: 5-[[4-[2- (2-Pyridinylamino) ethoxy]phenyl]methyl]-2, 4-thiazolidinedione; SB 237216. Grades: Highly Purified. CAS No. 257892-31-2. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
N-Desmethyl Rosiglitazone. (5- [ [4- [2- (2-pyridinylamino] ethoxy] phenyl] methyl] -2, 4-thiazolidinedione) Quick inquiry Where to buy Suppliers range | A metabolite of Rosiglitazone. Group: Biochemicals. Alternative Names: 5- [ [4- [2- (2-pyridinylamino] ethoxy] phenyl] methyl] -2, 4-thiazolidinedione. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
2-Methyl-2-pyridylaminoethanol Quick inquiry Where to buy Suppliers range | 2-Methyl-2-pyridylaminoethanol is used as a reagent to synthesize Rosiglitazone (Maleate: R693500), a thiazolinedione drug used to reduce insulin resistance in patients with Type 2 diabetes. Group: Biochemicals. Grades: Highly Purified. CAS No. 122321-04-4. Pack Sizes: 500mg, 5g. Molecular Formula: C8H12N2O, Molecular Weight: 152.19. US Biological Life Sciences. | Worldwide |
5-{4- [2- [ (5-Benzyloxypyridin-2-yl) methylamino] ethoxy] benzyl}thiazolidine-2, 4-dione Quick inquiry Where to buy Suppliers range | 5-{4- [2- [ (5-Benzyloxypyridin-2-yl) methylamino] ethoxy] benzyl}thiazolidine-2, 4-dione. Group: Biochemicals. Alternative Names: 5- [ [3- [2- [Methyl [5- (phenylmethoxy) -2-pyridinyl] amino] ethoxy] phenyl] methyl] -2, 4-thiazolidinedione; 5-Benzyloxy rosiglitazone. Grades: Highly Purified. CAS No. 326496-05-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C25H25N3O4S. US Biological Life Sciences. | Worldwide |
Balaglitazone Quick inquiry Where to buy Suppliers range | The Rs for the separations were 3.5 for balaglitazone enantiomers, 3.5 for pioglitazone enantiomers, and 3.7 for rosiglitazone. The squared correlation coefficients (r2) were found to be 0.999 for all three compounds. Balaglitazone treated groups shown significantly reduce of HbA1c (%), FSG (mmol/L), postprandial glucose as comparison to pioglitazone. Balaglitazone 10 mg and 20 mg show the similar magnitudes of the effects which comparable to the effects seen in the pioglitazone 45 mg group. The incidence of fluid retention and fat accumulation fewer than those observed with pioglitazone 45 mg. Sixty male dio induced obese rats were divided into five categories: vehicle, pioglitazone 10 mg/kg, pioglitazone 30 mg/kg, balaglitazone 5 mg/kg, balaglitazone 10 mg/kg. At day -7, 21 and 42 fasting serum samples were collected and whole body tissue composition was evaluated by MR scanning. Synonyms: DRF-2593; NN-2344; DRF2593; NN2344; DRF 2593; NN 2344. Grades: >98%. CAS No. 199113-98-9. Molecular formula: C20H17N3O4S. Mole weight: 395.43. | |
CAY10573 Quick inquiry Where to buy Suppliers range | Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors of nuclear hormone receptor superfamily comprising of the following three subtypes: PPARα, PPARγ, and PPARβ/&delta. CAY10573 is a PPAR agonist that displays potent binding at PPARα, γ, and δ with IC50 values of 113, 50, and 223 nM, respectively. It shows stronger binding and functional activity for PPARγ than the antidiabetic compound rosiglitazone (IC50 = 92 nM; EC50 = 220 nM). Synonyms: CAY 10573; CAY-10573. Grades: ≥98%. CAS No. 853652-40-1. Molecular formula: C33H31NO5. Mole weight: 521.6. | |
CAY10599 Quick inquiry Where to buy Suppliers range | Peroxisome proliferator-activated receptor gamma (PPARγ), also known as the glitazone receptor, or NR1C3, is a type II nuclear receptor that in humans is encoded by the PPARG gene. CAY10599 is a PPARγ agonist that is 4-fold more potent than rosiglitazone at PPARγ with an EC50 of 0.05 μM. It shows high selectivity for the PPARγ receptor over PPARβ (EC50 > 10 μM) or PPARα (EC50 = 3.99 μM). Synonyms: CAY 10599; CAY-10599. Grades: ≥98%. CAS No. 1143573-33-4. Molecular formula: C38H41NO5. Mole weight: 591.7. | |
G3335 Quick inquiry Where to buy Suppliers range | G3335 is a cell-permeable dipeptide that selectively and reversibly antagonizes PPARγ with a Kd value of 8.34 μM. G3335 reversiblyand competitively blocks activation of PPARγ by rosiglitazone. Synonyms: tryptophanyl-glutamic acid; Tryptophyl-Glutamate; L-Trp-L-Glu; L-tryptophyl-L-glutamic acid; N-L-Tryptophyl-L-glutamic acid; (S)-2-[(S)-2-Amino-3-(1H-indol-3-yl)-propionylamino]-pentanedioic acid. Grades: ≥98%. CAS No. 36099-95-3. Molecular formula: C16H19N3O5. Mole weight: 333.34. | |
G3335 acetate Quick inquiry Where to buy Suppliers range | G3335 acetate is a cell-permeable dipeptide that selectively and reversibly antagonizes PPARγ with a Kd of 8.34 μM. G3335 reversibly and competitively blocks activation of PPARγ by rosiglitazone. Synonyms: H-Trp-Glu-OH.CH3CO2H; WE acetate; L-tryptophyl-L-glutamic acid acetic acid; Acetic acid, compd. with L-tryptophyl-yl L-Glutamate (1:1). Grades: ≥95%. CAS No. 2760881-52-3. Molecular formula: C18H23N3O7. Mole weight: 393.39. | |
MHY 908 Quick inquiry Where to buy Suppliers range | MHY 908 is a dual PPARα/γ agonist and a melanogenesis inhibitor that suppresses mushroom tyrosinase activity (IC50 value 8.19 μM). MHY908 exhibits more potent activation of PPARα and PPARγ than fenofibrate and rosiglitazone, and enhances the binding and transcriptional activity of PPARα and -γ in AC2F cells. It reduces serum glucose, triglyceride, and insulin levels, however increases adiponectin levels without body weight gain. Synonyms: MHY908; MHY 908; MHY-908; 2-[4-(5-Chloro-2-benzothiazolyl)phenoxy]-2-methylpropanoic acid. Grades: 99%. CAS No. 1393371-39-5. Molecular formula: C17H14ClNO3S. Mole weight: 347.82. | |
mitoNEET Inhibitor NL-1, Thiazolidinedione (5-(3,5-di-tert-butyl-4-hydroxybenzyl)-4-hydroxythiazol-2(5H)-one) Quick inquiry Where to buy Suppliers range | A cell-permeable, thiazolidinedione (TZD) that acts as an inhibitor of MitoNEET (IC50=0.9uM) in competition with rosiglitazone and pioglitazone, in liver mitochondrial suspensions. In pharmacological studies, it was found to alter isolated mitochondrial complex I respiration with an IC50 of 2.4uM and inhibited State III respiration up to 45%. Furthermore, this compound (6-25uM) is shown to dose-dependently reduce lactate-dehydrogenase release in SH-SY5Y cultures, leading to a 40% decrease in rotenone-induced cell-death. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
PPAR Agonist IX, GQ-16 ((Z)-5-(5-Bromo-2-methoxybenzylidene)-3-(4-methyl-benzyl)-thiazolidine-2,4-dione) Quick inquiry Where to buy Suppliers range | A cell-permeable thiazolidinedione that acts as a PPARg-selective agonist (Ki=160nM) and blocks Cdk-5-mediated Ser273 phosphorylation by stabilizing PPARg b-sheet structure, exhibiting no detectable activity towards PPARa, PPARd, or RXRa. Although a weaker PPAPg agonist than Thiazolidinediones (TZDs) family rosiglitazone (Max. fold of transactivation induction =8.57 and 24.8 with 10uM respective compound in U-937 reporter assays), GQ-16 can be safely administered at a higher dosage (20mg/kg/day; oral gavage) in mice to achieve similar in vivo efficacy as rosiglitazone (4mg/kg/day; o.g.) without adverse side effects commonly seen with TZDs. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |