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S 14506 is a potent and selective 5-HT1A agonist. Synonyms: S-14506; S 14506; S14506; 4-fluoro-N-[2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl]benzamide. Grades: 98%. CAS No. 135722-25-7. Molecular formula: C24H26FN3O2. Mole weight: 407.48.
S 14506 hydrochloride
S 14506 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 286369-38-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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S 14506 hydrochloride
S 14506 hydrochloride is a highly potent and selective 5-HT1A receptor full agonist (pKi = 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors, respectively). S 14506 possibly binds between the agonist binding site and the G protein interaction switch site. S 14506 exhibits anxiolytic and antihypertensive properties. Synonyms: S 14506 hydrochloride; S14506 hydrochloride; S-14506 hydrochloride; 4-Fluoro-N-[2-[4-(7-methoxy-1-naphthalenyl)-1-piperazinyl]ethyl]benzamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 286369-38-8. Molecular formula: C24H26FN3O2.HCl. Mole weight: 443.94.
Desmethyl-S 14506
Desmethyl-S 14506 is a precursor for S 14506, a 5-HT1A agonist, which can be used for PET study. Synonyms: 4-fluoro-N-[2-[4-(7-hydroxynaphthalen-1-yl)piperazin-1-yl]ethyl]benzamide. Grades: 98%. CAS No. 135722-26-8. Molecular formula: C23H24FN3O2. Mole weight: 393.45.
PD 145065 - CAS 153049-49-1
A highly potent but non-selective endothelin receptor antagonist [IC??= 4 nM for the ETA receptor (rabbit renal artery vascular smooth muscle cells); IC?? = 15 nM for the ETB receptor (rat cerebellum)]. Group: Fluorescence/luminescence spectroscopy.
S14506 HCl
S 14506 is a highly potent selective 5-HT1A receptor full agonist (pKi values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors respectively). It potentially binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S 14506 HCl; S14506HCl; S14506 HCl; S-14506. Product Category: Agonists. Appearance: Solid powder. CAS No. 286369-38-8. Molecular formula: C24H27ClFN3O2. Mole weight: 443.95. Purity:>98%. IUPACName: 4-Fluoro-N-[2-[4-(7-methoxy-1-naphthalenyl)-1-piperazinyl]ethyl]benzamide hydrochloride. Canonical SMILES: O=C(NCCN1CCN(C2=C3C=C(OC)C=CC3=CC=C2)CC1)C4=CC=C(F)C=C4.[H]Cl. Product ID: ACM286369388. Alfa Chemistry ISO 9001:2015 Certified.
2-Butyl-4,5-dichloro-1H-imidazole
2-Butyl-4,5-dichloro-1H-imidazole is derived from 2-Butyl-5-chloroimidazole-4-methanol (B690640), which is an impurity of Losartan. Group: Biochemicals. Grades: Highly Purified. CAS No. 145061-99-0. Pack Sizes: 100mg, 500mg. Molecular Formula: C7H10Cl2N2, Molecular Weight: 193.07. US Biological Life Sciences.
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3-(2-Propenyl)adenine
9-(2-Propenyl)adenine is an N-substituted purine with DNA binding potential and cancer-initiating effect. 3-(2-Propenyl)adenine is a noncompetitive inhibitor of nonspecific adenosine deaminase from Taka-Diastase. Group: Biochemicals. Alternative Names: 3-Allyladenine; 3-(2-Propen-1-yl)-3H-purin-6-amine; NSC 145068. Grades: Highly Purified. CAS No. 13532-34-8. Pack Sizes: 10mg. US Biological Life Sciences.
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4-ETHYNYL-2-FLUORO-1-METHYL-BENZENE
4-ETHYNYL-2-FLUORO-1-METHYL-BENZENE. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-ETHYNYL-2-FLUORO-1-METHYL-BENZENE;Benzene, 4-ethynyl-2-fluoro-1-methyl- (9CI). Product Category: Heterocyclic Organic Compound. CAS No. 145069-53-0. Molecular formula: C9H7F. Mole weight: 134.1502832. Purity: 0.96. IUPACName: 4-ethynyl-2-fluoro-1-methylbenzene. Canonical SMILES: CC1=C(C=C(C=C1)C#C)F. Density: 1.04g/cm³. Product ID: ACM145069530. Alfa Chemistry ISO 9001:2015 Certified.
Benzenemethanol,4-chloro-a-2-propen-1-yl-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(4-Chlorophenyl)-3-buten-1-ol, 14506-33-3, 4-(4-Chlorophenyl)-1-buten-4-ol, AC1MBWMR, ACMC-20apb1, SureCN867450, AGN-PC-008LPR, 561010_ALDRICH, CTK4C4341, 1-(4-chlorophenyl)but-3-en-1-ol, 1-(4-chlorophenyl)-but-3-en-1-ol, AKOS010638320, 1-(4-chloro-phenyl)-but-3-en-1-ol, (1S)-1-(4-chlorophenyl)but-3-en-1-ol, Benzenemethanol,4-chloro-a-2-propen-1-yl-, KB-186981, KB-214609, (R)-1-(4-CHLOROPHENYL)BUT-3-EN-1-OL, (S)-1-(4-CHLOROPHENYL)BUT-3-EN-1-OL, I14-33653. Product Category: Heterocyclic Organic Compound. CAS No. 14506-33-3. Molecular formula: C10H11ClO. Mole weight: 182.65. Purity: 0.96. IUPACName: 1-(4-chlorophenyl)but-3-en-1-ol. Canonical SMILES: C=CCC(C1=CC=C(C=C1)Cl)O. Density: 1.137 g/mL at 25ºC(lit.). Product ID: ACM14506333. Alfa Chemistry ISO 9001:2015 Certified.
CPI-169
CPI-169 is a novel and potent EZH2 inhibitor, it decreases cellular levels of H3K27me3 and triggers cell cycle arrest and apoptosis in a variety of cell lines. Synonyms: CPI-169; CPI 169; CPI169. Grades: >98%. CAS No. 1450655-76-1. Molecular formula: C27H36N4O5S. Mole weight: 528.66.
N-(8Z-Heptadecen-1-yl)-O-(3-pyridylmethyl)carbamate acts as an inhibitor of fatty acid amide hydrolase (FAAH). It decreased cell viability of non-small lung cancer cells A549 and H460 with IC50 of 4.9 and 0.9 μM, respectively. Synonyms: Pyridin-3-ylmethyl N-[(Z)-heptadec-8-enyl]carbamate. Grades: ≥98%. CAS No. 1450603-63-0. Molecular formula: C24H40N2O2. Mole weight: 388.6.
NU 9056
NU 9056. Group: Biochemicals. Grades: Purified. CAS No. 1450644-28-6. Pack Sizes: 10mg. US Biological Life Sciences.
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NU 9056
NU 9056 is a selective KAT5 (Tip60) histone acetyltransferase inhibitor (IC50 = < 2, 60, 36, and>100 μM for KAT5, p300, pCAF and GCN5, respectively). NU 9056 treatment inhibited cellular proliferation in a panel of prostate cancer cell lines (50% growth inhibition, 8-27 μM) and induced apoptosis via activation of caspase 3 and caspase 9 in a concentration- and time-dependent manner. Also, decreased androgen receptor, prostate specific antigen, p53 and p21 protein levels were demonstrated in response to treatment with NU 9056. Synonyms: NU 9056; NU9056; NU-9056; 5-(1,2-Thiazol-5-yldisulfanyl)-1,2-thiazole. CAS No. 1450644-28-6. Molecular formula: C6H4N2S4. Mole weight: 232.37.
1g Pack Size. Group: Building Blocks, Organics, Peptide Reagents. Formula: C32H29NO7. CAS No. 145069-56-3. Prepack ID 72830185-1g. Molecular Weight 539.58. See USA prepack pricing.
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