S Adenosyl L Methionine Suppliers USA
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Product | Description | |
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s-Adenosyl-L-methionine Quick inquiry Where to buy Suppliers range | s-Adenosyl-L-methionine. Group: Heterocyclic Organic Compound. Alternative Names: ADEMETIONINE; S-ADENOSYL-L-METHIONINE; SAM-E; adenosine, 5'-((l-3-amino-3-carboxypropyl)methylsulfonio)-5'-deoxy-, hydroxide, ; adenosylmethionine; methioninyladenylate; p-Toluenesulfonate salt;ADEMETHIOINEDISULFATETOSYLATE. CAS No. 29908-03-0. Molecular formula: C15H24N6O5S. Mole weight: 400.45. Safty Description: 53-23-36/37/39-45. | |
S-Adenosyl-L-methionine Quick inquiry Where to buy Suppliers range | S Adenosyl L methionine. CAS No. 29908-03-0. | |
S-Adenosyl-L-methionine Quick inquiry Where to buy Suppliers range | S-Adenosyl-L-methionine. Group: Biochemicals. Alternative Names: SAMe. Grades: Highly Purified. CAS No. 29908-03-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C15H22N6O5S, Molecular Weight: 398.44. US Biological Life Sciences. | Worldwide |
S-Adenosyl-L-Methionine Quick inquiry Where to buy Suppliers range | S-adenosyl-l-methionine (SAMe) is a naturally occurring substance which is a major source of methyl groups in the brain. The efficacy of SAMe in treating depressive syndromes and disorders is superior to that of placebo and comparable to that of standard tricyclic antidepressants. Since SAMe is a naturally occurring compound with relatively few side effects, it is a potentially important treatment for depression. S-adenosylmethionine (SAMe) is a dietary supplement used in the management of osteoarthritis (OA) symptoms. Studies evaluating SAMe in the management of OA have been limited to Non Steroidal Anti-inflammatory Drugs (NSAIDs) for comparison. The present study compares the effectiveness of SAMe to a cyclooxygenase-2 (COX-2) inhibitor (celecoxib) for pain control, functional improvement and to decrease side effects in people with osteoarthritis of the knee. It also acts as a PDE4B inhibitor. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Ademetionine; AdoMet; MSI-195; MSI 195; MSI195; SAMe; S-adenosylmethionine. Heptral; Gumbaral. S-Adenosyl-L-methionine; S-Adenosyl methionine; SAMe; AdoMet; (2S)-2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylsulfonio]butanoate. Grades: 98%. CAS No. 29908-03-0. Molecular formula: C15H22N6O5S. Mole weight: 398.438. | |
S-Adenosyl-L-methionine 1,4-butanedisulfonate sodium salt Quick inquiry Where to buy Suppliers range | S Adenosyl L methionine 1,4 butanedisulfonate sodium salt. CAS No. 101020-79-5. | |
S-Adenosyl-L-methionine disulfate tosylate Quick inquiry Where to buy Suppliers range | S Adenosyl L methionine disulfate tosylate. CAS No. 97540-22-2. | |
S-Adenosyl-L-methionine Disulfate Tosylate (doMet SAM Disulfate p-toluenesulfonate, SAMe) Quick inquiry Where to buy Suppliers range | A methyl donor and a cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. SAM is anti-apoptotic in normal hepatocytes and normal colon epithelial cells but pro-apoptotic in liver human hepatocellular carcinoma (HCC), HepG2 cells and colon cancer cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 97540-22-2. Pack Sizes: 50g, 100g, 250g, 500g. Molecular Formula: C??H??N?O??S?, Molecular Weight: 766.8. US Biological Life Sciences. | Worldwide |
S-Adenosyl-L-methionine p-toluenesulfonate Quick inquiry Where to buy Suppliers range | S Adenosyl L methionine p toluenesulfonate. CAS No. 86562-85-8. | |
S-Adenosyl-L-methionine p-toluenesulfonate Quick inquiry Where to buy Suppliers range | S-Adenosyl-L-methionine p-toluenesulfonate, a vital compound harnessed within the biomedical sector, assumes a pivotal position as a cofactor amidst the intricate processes involved in neurotransmitter, DNA, and protein synthesis. Predominantly employed to address myriad liver afflictions such as chronic liver disease and cholestasis, this product's therapeutic efficacy extends to mood disorders by fostering regulation of neurotransmitter equilibrium, specifically targeting depression. Synonyms: S-(5'-Adenosyl)-L-methionine tosylate; Adenosine, 5'-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-, 4-methylbenzenesulfonate (1:1); Adenosine, 5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxy-, (3S)-, 4-methylbenzenesulfonate (salt); Adenosine, 5'-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-, salt with 4-methylbenzenesulfonic acid (1:1); S-Adenosylmethionine toluene-p-sulfonate; S-Adenosylmethionine tosylate; SAMe p-toluenesulfonate. Grades: 95%. CAS No. 52248-03-0. Molecular formula: C15H23N6O5S.C7H7O3S. Mole weight: 570.64. | |
S-Adenosyl-L-methionine p-toluenesulfonate Quick inquiry Where to buy Suppliers range | S-(5?-Adenosyl)-L-methionine (SAM) is anti-apoptotic in normal hepatocytes and normal colon epithelial cells but pro-apoptotic in liver human hepatocellular carcinoma (HCC), HepG2 cells and colon cancer cells. Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury. Group: Biochemicals. Alternative Names: (3S) -5'-[ (3-Amino-3-carboxylatopropyl) methylsulphonio]-5'-deoxyadenosine) ; SAMe p-toluenesulfonate; S-Adenosylmethionine Tosylate; Adomet; Ademetionine. Grades: Highly Purified. CAS No. 17176-17-9. Pack Sizes: 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
Ademethionine Disulfate Tosylate Quick inquiry Where to buy Suppliers range | Ademetionine Disulfate Tosylate is used to study the survival time in various damage brain models. Synonyms: 4-Methylbenzenesulfonate (salt) Sulfate (salt) (1:1:1:1) (9CI); FO 1561; S-Adenosyl-L-methionine Disulfate Tosylate; 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxyadenosine Sulfate 4-Methylbenzenesulfonate Sulfate; (3S)-5'-[(3-Amino-3-carboxyp. Grades: > 95%. CAS No. 97540-22-2. Molecular formula: C22H34N6O16S4. Mole weight: 766.8. | |
Ademetionine 1,4-butanedisulfonate Quick inquiry Where to buy Suppliers range | Ademetionine 1,4-butanedisulfonate. Group: Heterocyclic Organic Compound. Alternative Names: (3s)-5-[(3-amino-3-carboxypropyl)methylsulfonio]-5-deoxy-adenosine 1,4-butanedisulfonate 1,4-butanedisulfonate (2:1:2);Ademetionine 1,4-butanedisulfonate;s-adenosylmethionine 1,4-butanedisulfonate;Adenosine, 5-(3S)-3-amino-3-carboxypropylmethylsulfonio-5-deoxy-, 1,4-butanedisulfonate (salt), 1,4-butanedisulfonate (salt) (2:1:2);S-ADENOSYLMETHIONINE1,4-BUTANEDUSULFONATE;(3S)-5-[(3-Amino-3-carboxypropyl)methylsulfonio]-5-deoxy-adenosine 1,4-butanedisulfonate 1,4-butanedisulfonate (2:1:2);S-Adenosylmethione-1,4-butanedisulfonate;S-Adenosyl-L-methionine 1,4-butanedisulfonate sodium salt. Grades: 98%. CAS No. 101020-79-5. Molecular formula: 2C15H23N6O5S.2C4H10O6S2.C4H8O6S2. Mole weight: 1451.63. | |
Ademetionine disulfate tosylate Quick inquiry Where to buy Suppliers range | Ademetionine disulfate tosylate. Group: Heterocyclic Organic Compound. Alternative Names: 5'- ( (3-amino-3-carboxypropyl)methylsulfonio)-5'-deoxy-adenosin (s)-adenosinsaltw; adenosylmethioninetosylatebis (sulfate; fo-1561; ith4-methylbenzenesulfonicacid, sulfate (salt) (1: 1: 2); S-ADENOSYL-L-METHIONINE SULFATE P-TOLUENESULFONATE;S-ADENOSYL-L-METHIONINE SULFATE TOSYLATE;SAME-PTS;ADEMETHIONINE SULFATE TOSYLATE. CAS No. 97540-22-2. Molecular formula: C15H22N6O5S.C7H8O3S.2H2O4S. Mole weight: 766.8. | |
AMI-1 Quick inquiry Where to buy Suppliers range | AMI-1 is a cell-permeable inhibitor which inhibits protein arginine N-methyltransferase (PRMT) activity with IC50 of 8.81 μM for PRMT1 and IC50 of 3.04 μM for Hmt1p in vitro. MI-1 does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site and exhibits minimal effects on both SET (Sub39H1, Suv39H2, SET7) and non-SET (DOT1) lysine N-methyltransferases. Furthermore, AMI-1 prevents in vivo arginine methylation of cellular proteins and can modulate nuclear receptor-regulated transcription from estrogen and androgen response elements, thus operating as a brake on certain hormone actions. Synonyms: 7,7'-(Carbonyldiimino)bis[4-hydroxy-2-naphthalenesulfonic acid] disodium salt; 5,5'-Dihydroxy-2,2'-dinaphthylcarbamide-7,7'-disulfonic acid disodium salt; 6,6'-Ureylenebis(1-naphthol-3-sulfonic acid) disodium salt; 7,7'-Ureylenebis(4-hydroxy-2-naphthalenesulfonic acid) disodium salt; Carbonyl J disodium salt; I Acid Urea disodium salt; N,N'-Bis(5-hydroxy-7-sulfo-2-naphthyl)urea disodium salt; N,N'-Bis(7-sulfo-5-hydroxy-2-naphthyl)urea disodium salt; N,N'-Bis[1-hydroxy-3-sulfonaphthyl(6)]urea disodium salt; N,N'-Bis[1-oxy-3-sulfonaphthyl(6)]urea disodium salt; AMI-1 sodium salt; AMI 1; AMI1; J Acid Urea disodium salt. Grades: ≥98%. CAS No. 20324-87-2. Molecular formula: C21H14N2Na2O9S2. Mole weight: 548.45. | |
AMI-1 Quick inquiry Where to buy Suppliers range | Potent, cell permeable and specific protein arginine N-methyltransferase 1 (PRMT1) inhibitor (IC50 = 8.8uM). Does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site. Blocks peptide substrate binding. HIV-1 RT polymerase inhibitor (IC50 = 5.0uM). Group: Biochemicals. Alternative Names: Arginine N-methyltransferase inhibitor-1. Grades: Highly Purified. CAS No. 160994-87-6, 134-47-4. Pack Sizes: 5mg, 25mg. Molecular Formula: C21H12N2O9S2Na4. US Biological Life Sciences. | Worldwide |
Aminoethoxyvinyl glycine Hydrochloride (ABG 3168) Quick inquiry Where to buy Suppliers range | Ethylene, an important plant regulator, is synthesized from S-adenosyl-L-methionine by the sequential action of 1-amino-cyclopropane-carboxylate (ACC) synthases (ACSs) and ACC oxidases (ACOs). Aminoethoxyvinyl glycine is an inhibitor of ethylene biosynthesis that, at 1uM, blocks the activity of both ACSs and ACOs.1 Through this action, it reduces ethylene-mediated changes in plant growth and development.2,3,4 Aminoethoxyvinyl glycine also inhibits cystathionine γ-lyase (Ki = 10.5uM) with slow- and tight-binding characteristics.5. Group: Biochemicals. Alternative Names: (2S,3E)-2-Amino-4-(2-aminoethoxy)-3-butenoic Acid Monohydrochloride; [S-(E)]-2-Amino-4-(2-aminoethoxy)-3-butenoic Acid Monohydrochloride; (S)-trans-2-Amino-4-(2-aminoethoxy)-3-butenoic Acid Hydrochloride; ABG 3168 Hydrochloride; L-2-Amino-4-(2'-aminoethoxy)-trans-3-butenoic Acid Hydrochloride; ReTain Hydrochloride; ReTain (plant growth regulator) Hydrochloride. Grades: Highly Purified. CAS No. 55720-26-8. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C?H??ClN?O?, Molecular Weight: 196.63. US Biological Life Sciences. | Worldwide |
Kaempferide Quick inquiry Where to buy Suppliers range | Kaempferide is an O-methylated flavonol. It can be found in Kaempferia galanga (aromatic ginger). The enzyme kaempferol 4'-O-methyltransferase uses S-adenosyl-L-methionine and kaempferol to produce S-adenosyl-L-homocysteine and kaempferide. Uses: Antioxidant. Synonyms: 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-methoxyphenyl)-; 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one; Flavone, 3,5,7-trihydroxy-4'-methoxy-; 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one; 3,5,7-Trihydroxy-4'-methoxyflavone; 4'-Methoxykaempferol; 4'-Methylkaempferol; 4'-O-Methylkaempferol; 4'-O-Methylkaempherol; 5,7-Dihydroxy-4'-methoxyflavonol; Kaempferid; Kaempferol 4'-methyl ether; Kaempferol 4'-O-methyl ether; Kaempherol 4'-O-methyl ether; NSC 407294. Grades: >98%. CAS No. 491-54-3. Molecular formula: C16H12O6. Mole weight: 300.26. | |
Mitoguazone Quick inquiry Where to buy Suppliers range | Mitoguazone is a guanylhydrazone with potential antineoplastic activity. Mitoguazone competitively inhibits S-adenosyl-L-methionine decarboxylase (SAMD), an enzyme involved in the synthesis of polyamines, resulting in decreased proliferation of tumor cells, antimitochondrial effects, and p53-independent apoptosis. Polyamines, specifically spermine and spermidine, are essential for thymidine kinase production, DNA synthesis, and cell proliferation. Synonyms: MeGAG; methyl-G; methyl-GAG; MGBG; MGGH; DRG-0223; DRG 0223; DRG0223; NSC32946; NSC 32946; NSC-32946. Grades: 99.38%. CAS No. 459-86-9. Molecular formula: C5H12N8. Mole weight: 184.21. | |
PRMT Inhibitor VI (1- (Benzo[d][1, 2, 3]thiadiazol-6-yl) -3- (2-cyclohexenylethyl) urea, 1-(1,2,3-Benzothiadiazol-6-yl)-3-[2-(1-cyclohexen-1-yl)ethyl]urea, Protein Arginine Methyltransferase Inhibitor VI) Quick inquiry Where to buy Suppliers range | A benzothiadiazolyl-cyclohexenylethylurea compound that binds to protein arginine methyltransferase 3 at the dimer interface and selectively inhibits PRMT3 activity in an allosteric manner (IC50 = 1.6uM), while being non-competitive with respect to AdoMet (S-adenosyl-L-methionine; SAM) or peptide substrates (Ki = 2.9 and 4.2 mM, respectively). Exhibits little or no inhibitory activity against PRMT1/4/5/8 or protein lysine methyltransferases, EHMT1, SUV39H2, SETD7, and SETD8, even at concentrations above 100uM. Although cell-permeable, it is metabolically unstable and therefore not recommended for cell cultures or in vivo applications. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?OS, Primary Target: PRMT3. US Biological Life Sciences. | Worldwide |
S-(5'-Adenosyl)-L-methionine Chloride Dihydrochloride Quick inquiry Where to buy Suppliers range | S-(5?-Adenosyl)-L-methionine chloride dihydrochloride (SAM) facilitates the transfer of methyl groups to proteins, lipids and nucleic acids. Methionine adenosyl transferase catalyses the synthesis of SAM from methionine and adenosine triphosphate (ATP). SAM functions to regulate various cellular functions like cell division, cell death, transcription, genetic stability, oxidant/antioxidant balance and polyamine homeostasis. Therapeutically, SAM finds its application as a nutritional supplement in humans for various diseases like osteoarthritis and liver injury. SAM also regulates transsulfuration reactions by binding to the regulatory domain of key enzyme cystathionine- β-synthase (CBS).S-(5?-Adenosyl)-L-methionine chloride dihydrochloride has been used as a medium supplement for S30 cell extract. It also has been used for measuring the interaction with catechol-O-methyltransferase (COMT) by quartz crystal microbalance (QCM), surface plasmon resonance (SPR) and isothermal titration calorimetry (ITC) with supported lipid bilayers and vesicles. Group: Biochemicals. Alternative Names: 5'- [ [ (3S) -3-Amino-3-carboxypropyl] methylsulfonio] -5'-deoxyadenosine dihydrochloride; 5'-[ (L-3-Amino-3-carboxypropyl) methylsulfonio]-5'-deoxyadenosine dihydrochloride; S-Adenosylmethionine dihydrochloride; SAM chloride dihydrochloride; Active Methionine Disulfate; Ademetionine dihydrochloride; L-S-Adenosylmethionin dihydrochloride; S-Adenosyl-L-methionine dihydrochloride. Grades: Purified. CAS No. 86867-01-8. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C15H23ClN6O5S·2HCl, Molecular Weight: 507.82. US Biological Life Sciences. | Worldwide |
S-(5'-Adenosyl)-L-Methionine-d3 Disulfate Salt (Mixture of Diastereomers) Quick inquiry Where to buy Suppliers range | Labelled S-(5-Adenosyl)-L-methionine. Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury. Group: Biochemicals. Alternative Names: 5-[[(3S)-3-Amino-3-carboxypropyl](methyl-d3)sulfonio]-5-deoxyadenosine Disulfate; 5-[(L-3-Amino-3-carboxypropyl)(methyl-d3)sulfonio]-5-deoxyadenosine Disulfate; S-Adenosylmethionine-d3 Disulfate; Active Methionine-d3 Disulfate; Ademetionine-d3 Disulfate; L-S-Adenosylmethionin-d3 Disulfate; S-Adenosyl-L-methionine-d3 Disulfate. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C??H??D?N?O??S?, Molecular Weight: 597.61. US Biological Life Sciences. | Worldwide |
S-(5'-Adenosyl)-L-Methionine Disulfate Quick inquiry Where to buy Suppliers range | Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury. Group: Biochemicals. Alternative Names: 5'- [ [ (3S) -3-Amino-3-carboxypropyl] methylsulfonio] -5'-deoxyadenosine Disulfate; 5'-[ (L-3-Amino-3-carboxypropyl) methylsulfonio]-5'-deoxyadenosine Disulfate; S-Adenosylmethionine Disulfate; Active Methionine Disulfate; Ademetionine Disulfate; L-S-Adenosylmethionin Disulfate; S-Adenosyl-L-methionine Disulfate. Grades: Highly Purified. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C15H26N6O13S, Molecular Weight: 594.59. US Biological Life Sciences. | Worldwide |
S-(5'-Adenosyl)-L-methionine Disulfate Salt (Mixture of Diastereomers) Quick inquiry Where to buy Suppliers range | Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury. Synonyms: 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxyadenosine Disulfate; 5'-[(L-3-Amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine Disulfate; S-Adenosylmethionine Disulfate; Active Methionine Disulfate; Ademetionine Disulfate; L-S-Adenosylmethionin Disulfate; S-Adenosyl-L-methionine Disulfate. Grades: 95%. Molecular formula: C15H26N6O13S3. Mole weight: 594.59. |