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| Product | Description | |
|---|---|---|
| Sacubitril impurity 11 | Sacubitril impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1038924-70-7. Molecular formula: C18H19NO. Mole weight: 265.36. Catalog: APB1038924707. |  |
| Sacubitril impurity 12 | Sacubitril impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1038924-71-8. Molecular formula: C18H22ClNO2. Mole weight: 319.83. Catalog: APB1038924718. | |
| Sacubitril Impurity 3 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Synonyms: (3S,5S)-5-biphenyl-4-ylmethyl-3-methylpyrrolidin-2-one; (3S,5S)-5-[(Biphenyl-4-yl)methyl]-3-methylpyrrolidin-2-one. Grades: > 95%. CAS No. 1038925-00-6. Molecular formula: C18H19NO. Mole weight: 265.36. |  |
| Sacubitril impurity 31 | Sacubitril impurity 31. Uses: For analytical and research use. Group: Impurity standards. CAS No. 153037-40-2. Molecular formula: C20H25NO3. Mole weight: 327.42. Catalog: APB153037402. | |
| Sacubitril Impurity 4 | Sacubitrilat is one of the impurities of Sacubitril which has been found to be an endopeptidase inhibitor and be effective in the treatment of hypertension and heart failure. Synonyms: LBQ-657; LBQ 657; LBQ657; Sacubitrilat; UNII-SPI5PBF81S; LBQ657; CHEMBL417007; (2R,4S)-4-(3-carboxypropanoylamino)-2-methyl-5-(4-phenylphenyl)pentanoic acid. Grades: 98%. CAS No. 149709-44-4. Molecular formula: C22H25NO5. Mole weight: 383.44. | |
| Sacubitril Impurity 5 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Synonyms: (αR,?γR)?-γ-[[(1,?1-Dimethylethoxy)?carbonyl]?amino]?-α-methyl-[1,?1'-biphenyl]?-4-pentanoic Acid. Grades: > 95%. CAS No. 1012341-56-8. Molecular formula: C23H29NO4. Mole weight: 383.49. | |
| Sacubitril Impurity 6 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Synonyms: (αS,?γR)?-γ-[[(1,?1-Dimethylethoxy)?carbonyl]?amino]?-α-methyl-[1,?1'-biphenyl]?-4-pentanoic Acid. Grades: > 95%. CAS No. 1012341-54-6. Molecular formula: C23H29NO4. Mole weight: 383.49. | |
| Sacubitril Impurity 7 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Synonyms: (αS,?γS)?-γ-[[(1,?1-Dimethylethoxy)?carbonyl]?amino]?-α-methyl-[1,?1'-biphenyl]?-4-pentanoic Acid. Grades: > 95%. CAS No. 1012341-52-4. Molecular formula: C23H29NO4. Mole weight: 383.49. | |
| LCZ696 (valsartan + sacubitril) impurity 19 | LCZ696 (valsartan + sacubitril) impurity 19. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,4R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid. CAS No. 1012341-54-6. Molecular formula: C23H29NO4. Mole weight: 383.48. Catalog: APB1012341546. | |
| LCZ696 (valsartan + sacubitril) impurity 20 | LCZ696 (valsartan + sacubitril) impurity 20. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,4R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid. CAS No. 1012341-56-8. Molecular formula: C23H29NO4. Mole weight: 383.48. Catalog: APB1012341568. | |
| LCZ696 (valsartan + sacubitril) impurity 21 | LCZ696 (valsartan + sacubitril) impurity 21. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid. CAS No. 1012341-52-4. Molecular formula: C23H29NO4. Mole weight: 383.48. Catalog: APB1012341524. | |
| Valsartan impurity 16 (sacubitril impurity 1) | Valsartan impurity 16 (sacubitril impurity 1). Uses: For analytical and research use. Group: Impurity standards. CAS No. 102341-56-8. Molecular formula: C23H29NO4. Mole weight: 383.48. Catalog: APB102341568. | |
| Valsartan Impurity 40 (Sacubitril impurity 40) | Valsartan Impurity 40 (Sacubitril impurity 40). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1038924-97-8. Molecular formula: C24H27NO4. Mole weight: 393.48. Catalog: APB1038924978. | |
| Valsartan Impurity 48 (Sacubitril impurity 48) | Valsartan Impurity 48 (Sacubitril impurity 48). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1012341-48-8. Molecular formula: C23H27NO4. Mole weight: 381.46. Catalog: APB1012341488. | |
| Valsartan Impurity49 (Sacubitril impurity 49) | Valsartan Impurity49 (Sacubitril impurity 49). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1012341-50-2. Molecular formula: C23H29NO4. Mole weight: 383.49. Catalog: APB1012341502. | |
| 2,5-Dioxopyrrolidine Sacubitril | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Synonyms: (2R,4S)-5-Biphenyl-4-yl-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoic acid ethyl ester. CAS No. 1038924-97-8. Molecular formula: C24H27NO4. Mole weight: 393.483. | |
| 2,5-Dioxopyrrolidine Sacubitril | Sacubitril Impurity 2 is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan. Group: Biochemicals. Grades: Highly Purified. CAS No. 1038924-97-8. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C24H27NO4, Molecular Weight: 393.48. US Biological Life Sciences. |  Worldwide |
| (2R,4R)-Sacubitril | (2R,4R)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan. Group: Biochemicals. Grades: Highly Purified. CAS No. 766480-48-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H29NO5. US Biological Life Sciences. | Worldwide |
| (2R,4R)-Sacubitril | (2R,4R)-Sacubitril. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (?R,?R)-rel-?-[(3-Carboxy-1-oxopropyl)amino]-?-methyl-[1,1'-biphenyl]-4-pentanoic Acid 4-Ethyl Ester, Sacubitril-(2R,4R) Isomer,Impurity B,(R*,R*)-?-[(3-Carboxy-1-oxopropyl)amino]-?-methyl-[1,1'-biphenyl]-4-pentanoic Acid ?-Ethyl Ester. CAS No. 766480-48-2. IUPAC Name: (4Z)-4-[4-ethoxy-3-methyl-4-oxo-1-[(4-phenylphenyl)methyl]butyl]imino-4-hydroxy-butanoic acid. Molecular formula: C24H29NO5. Mole weight: 411.49. Catalog: APS766480482. SMILES: CCOC(=O)C(C)CC(Cc1ccc(cc1)c2ccccc2)\N=C(/O)\CCC(=O)O. Format: Neat. | |
| (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid | (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid is an impurity of Sacubitril, an endopeptidase inhibitor that is effective in the treatment of hypertension and heart failure. Synonyms: (2R,4S)-5-(4-Biphenylyl)-4-(2,5-dioxo-1-pyrrolidinyl)-2-methylpentanoic acid. CAS No. 1639970-62-9. Molecular formula: C22H23NO4. Mole weight: 365.422. | |
| (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoic acid | (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoic acid is an impurity of Sacubitril, an endopeptidase inhibitor that is effective in the treatment of hypertension and heart failure. Synonyms: Sacubitril impurity 16; Valsartan Impurity; (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoic acid. CAS No. 149709-49-9. Molecular formula: C24H29NO5. Mole weight: 411.49. | |
| (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride | (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride is an impurity of Sacubitril, an endopeptidase inhibitor that is effective in the treatment of hypertension and heart failure. Synonyms: Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride; (αR,γS)-γ-Amino-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid Ethyl Ester Hydrochloride; (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride. CAS No. 149690-12-0. Molecular formula: C20H26ClNO2. Mole weight: 347.88. | |
| (2R,4S)-4-Amino-5-biphenyl-4-yl-2-methylpentanoic acid hydrochloride | An impurity of Sacubitril, a neprilysin inhibitor that is used in combination with valsartan to treat high blood pressure. Synonyms: 1038924-71-8; (2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid hydrochloride(2R,4S)-4-amino-2-methyl-5-(4-phenylphenyl)pentanoic acid;hydrochloride; (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoic acid hydrochloride; SCHEMBL597864. CAS No. 1038924-71-8. Molecular formula: C18H22ClNO2. Mole weight: 319.8. | |
| (2R,4S)-5-Biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methylpentanoic acid | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Synonyms: 1012341-50-2; (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoic acid(2R,4S)-5-biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methylpentanoic acid; FJ7AWX8DMFUNII-FJ7AWX8DMF. CAS No. 1012341-50-2. Molecular formula: C23H29NO4. Mole weight: 383.488. | |
| (2R,4S)-Sacubitril-O-isobutane | (2R,4S)-Sacubitril-O-isobutane is an intermediate in the synthesis of (2S,4S)-Sacubitril (S080915). (2S,4S)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan. Group: Biochemicals. Grades: Highly Purified. CAS No. 149709-64-8. Pack Sizes: 500ug, 1mg. Molecular Formula: C28H37NO5. US Biological Life Sciences. | Worldwide |
| (2S,4R)-Sacubitril | (2S,4R)-Sacubitril is the enantiomer and an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan. Group: Biochemicals. Grades: Highly Purified. CAS No. 761373-05-1. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C24H29NO5. US Biological Life Sciences. | Worldwide |
| (2S,4R)-Sacubitril | (2S,4R)-Sacubitril. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: [1,1'-Biphenyl]-4-pentanoic acid, ?-[(3-carboxy-1-oxopropyl)amino]-?-methyl-, ?-ethyl ester, [R-(R*,S*)]- (9CI), (2S,4R)-4-[(3-Carboxy-1-oxopropyl)amino]-4-[(p-phenylphenyl)methyl]-2-methylbutanoic acid ethyl ester, (2S,4R)-Sacubitril, (2S,4R)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic acid ethyl ester,[1,1'-Biphenyl]-4-pentanoic acid, ?-[(3-carboxy-1-oxopropyl)amino]-?-methyl-, 4-ethyl ester, (?S,?R)-. CAS No. 761373-05-1. IUPAC Name: 4-[[(2R,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid. Molecular formula: C24H29NO5. Mole weight: 411.49. Catalog: APS761373051. SMILES: CCOC(=O)[C@@H](C)C[C@H](Cc1ccc(cc1)c2ccccc2)NC(=O)CCC(=O)O. Format: Neat. | |
| (2S,4S)-Sacubitril | (2S,4S)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan. Group: Biochemicals. Grades: Highly Purified. CAS No. 149709-63-7. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C24H29NO5. US Biological Life Sciences. | Worldwide |
| (2S,4S)-Sacubitril | (2S,4S)-Sacubitril. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4-(((2S,4S)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid),4-(((2S,4S)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid,[S-(R*,R*)]-?-[(3-Carboxy-1-oxopropyl)amino]-?-methyl-[1,1'-biphenyl]-4-pentanoic Acid Ethyl Ester, 4-(((2S,4S)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic Acid, Sacubitril-(2S,4S) Isomer. CAS No. 149709-63-7. IUPAC Name: (4Z)-4-[(1S)-4-ethoxy-3-methyl-4-oxo-1-[(4-phenylphenyl)methyl]butyl]imino-4-hydroxy-butanoic acid. Molecular formula: C24H29NO5. Mole weight: 411.49. Catalog: APS149709637. SMILES: CCOC(=O)C(C)C[C@@H](Cc1ccc(cc1)c2ccccc2)\N=C(/O)\CCC(=O)O. Format: Neat. | |
| (2S,4S)-Sacubitril-O-isobutane | (2S,4S)-Sacubitril-O-isobutane is an intermediate in the synthesis of (2S,4S)-Sacubitril (S080915). (2S,4S)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan. Group: Biochemicals. Grades: Highly Purified. CAS No. 149709-65-9. Pack Sizes: 500ug, 1mg. Molecular Formula: C28H37NO5. US Biological Life Sciences. | Worldwide |
| (3R,5S)-5-Biphenyl-4-ylmethyl-3-methylpyrrolidin-2-one | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Synonyms: 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)-. CAS No. 1038924-70-7. Molecular formula: C18H19NO. Mole weight: 265.356. | |
| (3S,5R)-4-[5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-2-oxopyrrolidin-1-yl]-4-oxobutanoic acid | (3S,5R)-4-[5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-2-oxopyrrolidin-1-yl]-4-oxobutanoic acid is an impurity of Sacubitril, an endopeptidase inhibitor that is effective in the treatment of hypertension and heart failure. Synonyms: 4-[(3R,5S)-5-(4-Biphenylylmethyl)-3-methyl-2-oxo-1-pyrrolidinyl]-4-oxobutanoic acid. CAS No. 2216746-87-9. Molecular formula: C22H23NO4. Mole weight: 365.422. | |
| Desethyl Sacubitril | Desethyl Sacubitril. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS001486. Format: Neat. | |
| Desethyl Sacubitril-d4 | Desethyl Sacubitril-d4. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS001487. Format: Neat. | |
| Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoate | Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoate is an impurity of Sacubitril, an endopeptidase inhibitor that is effective in the treatment of hypertension and heart failure. CAS No. 2376611-98-0. Molecular formula: C26H33NO5. Mole weight: 439.54. | |
| Propan-2-yl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-[4-(propan-2-yloxy)-4-oxobutanamido]butanoate | Propan-2-yl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-[4-(propan-2-yloxy)-4-oxobutanamido]butanoate is an impurity of Sacubitril, an endopeptidase inhibitor that is effective in the treatment of hypertension and heart failure. Synonyms: Isopropyl (2R,4S)-5-(4-biphenylyl)-4-[(4-isopropoxy-4-oxobutanoyl)amino]-2-methylpentanoate. CAS No. 2216755-67-6. Molecular formula: C28H37NO5. Mole weight: 467.6. | |
| ((R)-2-Biphenyl-4-yl-1-formylethyl)carbamic Acid t-Butyl Ester | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. CAS No. 149709-58-0. Molecular formula: C20H23NO3. Mole weight: 325.408. | |
| (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid | (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid is an impurity of Sacubitril, an endopeptidase inhibitor that is effective in the treatment of hypertension and heart failure. Synonyms: (2E,4R)-5-[1,1'-biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-2-Pentenoicacid; 5-Biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methyl-pent-2-enoicacid; 2-Pentenoicacid, 5-[1, 1'-biphenyl]-4-yl-4-[[ (1, 1-dimethylethoxy) carbonyl]aminChemicalbooko]-2-methyl-, (2E,4R)-; (R)-5-biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methyl-pent-(E)-2-enoic acid; SCHEMBL18765. Grades: 95%. CAS No. 1012341-48-8. Molecular formula: C23H27NO4. Mole weight: 381.46. | |
| (R)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoate | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. CAS No. 149709-59-1. Molecular formula: C25H31NO4. Mole weight: 409.526. | |
| Sacubitril-(2S, 4S)-Isomer | Sacubitril-(2S, 4S)-isomer.Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Synonyms: (2S,4S)-Sacubitril; 149709-63-7; 4-(((2S,4S)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid; 4-[[(2S,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid; [1,1'-Biphenyl]-4-pentanoic acid, gamma-[(3-carboxy-1-oxopropyl)amino]-alpha-methyl-, alpha-ethyl ester, (alphaS,gammaS)-; LCZ 696 Impurity C; SCHEMBL18059568; DTXSID901127620; AKOS030528363; AS-80403; HY-78841; CS-0009335; 3-{[(2S,4S)-1-{[1,1'-biphenyl]-4-yl}-5-ethoxy-4-methyl-5-oxopentan-2-yl]carbamoyl}propanoic acid; 4-(((2S,4S)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoicacid; alpha-Ethyl (alphaS,gammaS)-gamma-[(3-carboxy-1-oxopropyl)amino]-alpha-methyl[1,1'-biphenyl]-4-pentanoate. Grades: > 95%. CAS No. 149709-63-7. Molecular formula: C24H29NO5. Mole weight: 411.5. | |
| Sacubitril N-Boc Ester | Sacubitril N-Boc Ester is an impurity of Sacubitril, an endopeptidase inhibitor that is effective in the treatment of hypertension and heart failure. Synonyms: Ethyl (2R, 4S) -5- (4-biphenylyl) -2-methyl-4- ({[ (2-methyl-2-propanyl) oxy]carbonyl}amino) pentanoate; (αR,γS)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-Biphenyl]-4-pentanoic Acid Ethyl Ester; [1,1'-Biphenyl]-4-pentanoic acid, gamma-[[(1,1-dimethylethoxy)carbonyl]amino]-alpha-methyl-, ethyl ester, (alphaR,gammaS)-; Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-4-[(tert-butoxycarbonyl)amino]-2-methylbutanoate. CAS No. 149709-60-4. Molecular formula: C25H33NO4. Mole weight: 411.53. | |
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