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Sanglifehrin A It is a cyclophilin combination produced by the strain of Streptomyces sp. A92-308110. The affinity of Sanglifehrin A to Cyclophilin is 10-20 times stronger than Cyclosporin A. The immunosuppressive effect of Sanglifehrin is lower than Cyclosporin A by mixed lymphocyte reaction assay. Synonyms: SFA; (-)-sanglifehrin A; 19-Oxa-1,4,7,25-tetraazabicyclo[19.3.1]pentacosa-13,15-diene-2,5,8,20-tetrone, 18-[(1E,3E,7S,8S)-9-[(2S,3R,4S,5S,6R,9S,11S)-9-ethyl-4-hydroxy-3,5,11-trimethyl-8-oxo-1-oxa-7-azaspiro[5.5]undec-2-yl]-8-hydroxy-1,7-dimethyl-1,3-nonadienyl]-10,12-dihydroxy-3-[(3-hydroxyphenyl)methyl]-11-methyl-6-(1-methylethyl)-9-(3-oxobutyl)-, (3S, 6S, 9R, 10R, 11S, 12S, 13E, 15E, 18S, 21S)-. CAS No. 187148-13-6. Molecular formula: C60H91N5O13. Mole weight: 1090.39. BOC Sciences 5
Sanglifehrin B It is a cyclophilin combination produced by the strain of Streptomyces sp. A92-308110. The affinity of Sanglifehrin B to Cyclophilin is 10-20 times stronger than Cyclosporin A. The immunosuppressive effect of Sanglifehrin is lower than Cyclosporin A by mixed lymphocyte reaction assay. Synonyms: SFB. Molecular formula: C60H89N5O12. Mole weight: 1072.37. BOC Sciences 5
Sanglifehrin C It is a cyclophilin combination produced by the strain of Streptomyces sp. A92-308110. The affinity of Sanglifehrin C to Cyclophilin is similar to Cyclosporin A. The immunosuppressive effect of Sanglifehrin is lower than Cyclosporin A by mixed lymphocyte reaction assay. Synonyms: SFC. Molecular formula: C61H93N5O13. Mole weight: 1104.41. BOC Sciences 5
Sanglifehrin D It is a cyclophilin combination produced by the strain of Streptomyces sp. A92-308110. The affinity of Sanglifehrin D to Cyclophilin is similar to Cyclosporin A. The immunosuppressive effect of Sanglifehrin is lower than Cyclosporin A by mixed lymphocyte reaction assay. Synonyms: SFD. Molecular formula: C61H91N5O12. Mole weight: 1086.40. BOC Sciences 5

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