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Selamectin, a semi-synthetic macrocyclic lactone, is a potent parasiticide and anthelminthic. Selamectin activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent heartworm , Lymphatic filariae , and nematode infection. Selamectin is also a potent P-glycoprotein substrate and a P-glycoprotein inhibitor with an IC 50 of 120 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 220119-17-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107212.
Selamectin
Selamectin, a semi-synthetic macrocyclic lactone, is a potent parasiticide and anthelminthic. Selamectin activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent heartworm, Lymphatic filariae, and nematode infection. Selamectin is also a potent P-glycoprotein substrate and a P-glycoprotein inhibitor with an IC50 of 120 nM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Selamectin;hypnocarpic acid;AverMectin A1a,25-cyclohexyl-4-O-de(2,6-dideoxy-3-O-Methyl-a-L-arabino-hexopyranosyl)-5-deMethoxy-25-de(1-Methylpropyl)-22,23-dihydro-5-(hydroxyiMino)-,(5Z)-;(5Z)-25-Cyclohexyl-4-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-avermectin A1a;Revolution (antibiotic);Stronghold. Product Category: Inhibitors. Appearance: Solid. CAS No. 220119-17-5. Molecular formula: C43H63NO11. Mole weight: 769.967. Purity: 0.9905. Canonical SMILES: O[C@@]12[C@@]3([H])/C(C(C)=C[C@@]1([H])C(O[C@]4([H])C[C@]5(O[C@@](C/C=C(C)/[C@@H](O[C@@]6([H])C[C@@H]([C@@H](O)[C@H](C)O6)OC)[C@@H](C)/C=C/C=C2\CO3)([H])C4)O[C@H](C7CCCCC7)[C@@H](C)CC5)=O)=N\O. Product ID: ACM220119175. Alfa Chemistry ISO 9001:2015 Certified.
Selamectin
Selamectin. Group: Biochemicals. Alternative Names: Revolution (antibiotic); Stronghold; (5Z) -25-Cyclohexyl-4'-O-de (2, 6-dideoxy-3-O-methyl-α -L-arabino-hexopyranosyl) -5-demethoxy-25-de (1-methylpropyl) -22, 23-dihydro-5- (hydroxyimino) avermectin A1a. Grades: Highly Purified. CAS No. 220119-17-5. Pack Sizes: 10mg. US Biological Life Sciences.
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Selamectin
Seramectin is a semi-synthetic abamectin derivative. Seramectin is an effective nematicide for the treatment of endoparasites and ectoparasites in domestic animals (especially cats and dogs). It can selectively bind to the chloride channel gated by the parasite's glutamate and disrupt neurotransmission, leading to paralysis and parasite death. Synonyms: Revolution; Stronghold; (5Z)-25-Cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)avermectin A1a. Grade: ≥98%. CAS No. 220119-17-5. Molecular formula: C43H63NO11. Mole weight: 769.96.
22,23-Didehydro Selamectin
22,23-Didehydro Selamectin is an impurity of Selamectin (S247990) which is a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals. Group: Biochemicals. Grades: Highly Purified. CAS No. 165108-09-8. Pack Sizes: 5mg, 50mg. Molecular Formula: 2(C43H61NO11). US Biological Life Sciences.
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22,23-Didehydro Selamectin
22,23-Didehydro Selamectin. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 5MG. Catalog: APS004249. Format: Neat. Shipping: Room Temperature.
4'-O-2,6-Dideoxy-3-O-methyl-?-L-arabino-hexopyranosyl Selamectin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 301849-46-7. Pack Sizes: 5MG. Molecular formula: C50H75NO14. Mole weight: 914.13. Catalog: APS301849467. SMILES: CO[C@H]1C[C@H](O[C@H]2[C@H](C)O[C@H](C[C@@H]2OC)O[C@H]3[C@@H](C)\C=C\C=C\4/CO[C@@H]5C(=NO)C(=C[C@@H](C(=O)O[C@H]6C[C@@H](C\C=C\3/C)O[C@@]7(CC[C@H](C)[C@H](O7)C8CCCCC8)C6)[C@]45O)C)O[C@@H](C)[C@@H]1O. Format: Neat. Shipping: +20°C.
apo-Selamectin aglycone
apo-Selamectin aglycone.
22,23-Dihydro-25-cyclohexylavermectin B1
22,23-Dihydro-25-cyclohexylavermectin B1 is an intermediate in synthesizing 4'-O-2,6-Dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl Selamectin (D440100), which s an impurity of Selamectin (S247990), a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals. Group: Biochemicals. Grades: Highly Purified. CAS No. 142680-85-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C50H76O14. US Biological Life Sciences.
25-Cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)avermectin A1a is a racemic compound of Selamectin, which is an effective nematicide for the treatment of endoparasites and ectoparasites in domestic animals (especially cats and dogs). Uses: Antiparasitic agents. Synonyms: Avermectin A1a, 25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-; UK-124114. Grade: 95%. CAS No. 165108-07-6. Molecular formula: C43H63NO11. Mole weight: 769.97.
25-?Cyclohexyl-?4'-?O-?de (2, ?6-?dideoxy-?3-?O-?methyl-?α -?L-?arabino-?hexopyranosyl) ?-?5-?demethoxy-?25-?de (1-?methylpropyl) ?-?5-?oxo-avermectin A1a is an intermediate in synthesizing 22,23-Didehydro Selamectin (D439445), an impurity of Selamectin (S247990) which is a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals. Group: Biochemicals. Grades: Highly Purified. CAS No. 404578-37-6. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C43H60O11, Molecular Weight: 752.93. US Biological Life Sciences.
25-?Cyclohexyl-?4'-?O-?de (2, ?6-?dideoxy-?3-?O-?methyl-?α -?L-?arabino-?hexopyranosyl) ?-?5-?O-?demethyl-?25-?de (1-?methylpropyl) ?-Avermectin A1a is an intermediate in synthesizing 22,23-Didehydro Selamectin (D439445), an impurity of Selamectin (S247990) which is a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals. Group: Biochemicals. Grades: Highly Purified. CAS No. 165108-44-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C43H62O11, Molecular Weight: 754.95. US Biological Life Sciences.
25-Cyclohexyl-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-oxo-avermectin A1a is an intermediate in synthesizing 4'-O-2,6-Dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl Selamectin (D440100), which s an impurity of Selamectin (S247990), a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals. Group: Biochemicals. Grades: Highly Purified. CAS No. 220119-16-4. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C50H74O14. US Biological Life Sciences.
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