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| Product | Description | |
|---|---|---|
| Selamectin | Selamectin, a semi-synthetic macrocyclic lactone, is a potent parasiticide and anthelminthic. Selamectin activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent heartworm , Lymphatic filariae , and nematode infection. Selamectin is also a potent P-glycoprotein substrate and a P-glycoprotein inhibitor with an IC 50 of 120 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 220119-17-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107212. |  |
| Selamectin | Selamectin, a semi-synthetic macrocyclic lactone, is a potent parasiticide and anthelminthic. Selamectin activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent heartworm, Lymphatic filariae, and nematode infection. Selamectin is also a potent P-glycoprotein substrate and a P-glycoprotein inhibitor with an IC50 of 120 nM. Group: Inhibitors. Alternative Names: Selamectin;hypnocarpic acid;AverMectin A1a,25-cyclohexyl-4-O-de(2,6-dideoxy-3-O-Methyl-a-L-arabino-hexopyranosyl)-5-deMethoxy-25-de(1-Methylpropyl)-22,23-dihydro-5-(hydroxyiMino)-,(5Z)-;(5Z)-25-Cyclohexyl-4-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-avermectin A1a;Revolution (antibiotic);Stronghold. CAS No. 220119-17-5. Molecular formula: C43H63NO11. Mole weight: 769.967. Appearance: Solid. Purity: 0.9905. Canonical SMILES: O[C@@]12[C@@]3 ([H])/C (C (C)=C[C@@]1 ([H])C (O[C@]4 ([H])C[C@]5 (O[C@@] (C/C=C (C)/[C@@H] (O[C@@]6 ([H])C[C@@H] ([C@@H] (O)[C@H] (C)O6)OC)[C@@H] (C)/C=C/C=C2\CO3) ([H])C4)O[C@H] (C7CCCCC7)[C@@H] (C)CC5)=O)=N\O. Catalog: ACM220119175. |  |
| Selamectin | Selamectin. Group: Biochemicals. Alternative Names: Revolution (antibiotic); Stronghold; (5Z) -25-Cyclohexyl-4'-O-de (2, 6-dideoxy-3-O-methyl-α -L-arabino-hexopyranosyl) -5-demethoxy-25-de (1-methylpropyl) -22, 23-dihydro-5- (hydroxyimino) avermectin A1a. Grades: Highly Purified. CAS No. 220119-17-5. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Selamectin Impurity A | An impurity of selamectin. Selamectin is a topical parasiticide and anthelminthic used on animals. Synonyms: (2aE, 2'R, 4E, 4'S, 5'S, 6S, 6'R, 7S, 8E, 11R, 15S, 17aR, 20Z, 20aR, 20bS)-6'-cyclohexyl-7-[(2, 6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)oxy]-4', 20b-dihydroxy-20-(hydroxyimino)-5', 6, 8, 19-tetramethyl-3', 4', 5', 6, 6', 7, 10, 11, 14, 15, 17a, 20, 20a, 20b-tetradecahydrospiro[2H, 17H-11, 15-methanofuro[4, 3, 2-pq][2, 6]benzodioxacyclooctadecine-13, 2'-pyran]-17-one ((5Z,21R,23S,25R)-25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-23-hydroxy-5-(hydroxyimino)avermectin A1a). Grades: > 95%. Molecular formula: C43H63NO12. Mole weight: 785.96. |  |
| Selamectin Impurity B | An impurity of selamectin. Selamectin is a topical parasiticide and anthelminthic used on animals. Synonyms: 25-Cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-5-(hydroxyimino)-avermectin A1a; 22,23-Didehydro Selamectin. Grades: > 95%. CAS No. 165108-09-8. Molecular formula: C43H61NO11. Mole weight: 767.97. | |
| Selamectin Impurity C | An impurity of selamectin. Selamectin is a topical parasiticide and anthelminthic used on animals. Synonyms: (2aE, 2'R, 4E, 4'S, 5'S, 6S, 6'R, 7S, 8E, 11R, 15S, 17aR, 20Z, 20aR, 20bS)-6'-cyclohexyl-4', 7, 20b-trihydroxy-20-(hydroxyimino)-5', 6, 8, 19-tetramethyl-3', 4', 5', 6, 6', 7, 10, 11, 14, 15, 17a, 20, 20a, 20b-tetradecahydrospiro[2H, 17H-11, 15-methanofuro[4, 3, 2-pq][2, 6]benzodioxacyclooctadecine-13, 2'-pyran]-17-one ((5Z,13S,25R)-25-cyclohexyl-25-demethyl-5-deoxy-13-hydroxy-5-(hydroxyimino)milbemycin α1). Grades: > 95%. Molecular formula: C36H51NO9. Mole weight: 641.81. | |
| Selamectin Impurity D | An impurity of selamectin. Selamectin is a topical parasiticide and anthelminthic used on animals. Synonyms: 25-Cyclohexyl-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-avermectin A1a; 22,23-Dihydro-5-hydroxyimino Doramectin; 4'-O-2,6-Dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl Selamectin. Grades: > 95%. CAS No. 301849-46-7. Molecular formula: C50H75NO14. Mole weight: 914.15. | |
| 22,23-Didehydro Selamectin | 22,23-Didehydro Selamectin is an impurity of Selamectin (S247990) which is a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals. Group: Biochemicals. Grades: Highly Purified. CAS No. 165108-09-8. Pack Sizes: 5mg, 50mg. Molecular Formula: 2(C43H61NO11). US Biological Life Sciences. | Worldwide |
| 22,23-Didehydro Selamectin | 22,23-Didehydro Selamectin. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 5MG. Catalog: APS004249. Format: Neat. Shipping: Room Temperature. |  |
| 4'-O-2,6-Dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl Selamectin | 4'-O-2,6-Dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl Selamectin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 301849-46-7. Pack Sizes: 5MG. Molecular Formula: C50H75NO14. Mole Weight: 914.13. Catalog: APS301849467. SMILES: CO[C@H]1C[C@H] (O[C@H]2[C@H] (C)O[C@H] (C[C@@H]2OC)O[C@H]3[C@@H] (C)\C=C\C=C\4/CO[C@@H]5C (=NO)C (=C[C@@H] (C (=O)O[C@H]6C[C@@H] (C\C=C\3/C)O[C@@]7 (CC[C@H] (C)[C@H] (O7)C8CCCCC8)C6)[C@]45O)C)O[C@@H] (C)[C@@H]1O. Format: Neat. Shipping: +20°C. | |
| apo-Selamectin aglycone | | |
| 22,23-Dihydro-25-cyclohexylavermectin B1 | 22,23-Dihydro-25-cyclohexylavermectin B1 is an intermediate in synthesizing 4'-O-2,6-Dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl Selamectin (D440100), which s an impurity of Selamectin (S247990), a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals. Group: Biochemicals. Grades: Highly Purified. CAS No. 142680-85-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C50H76O14. US Biological Life Sciences. | Worldwide |
| 25-?Cyclohexyl-?4'-?O-?de (2, ?6-?dideoxy-?3-?O-?methyl-?α -?L-?arabino-?hexopyranosyl) ?-?5-?demethoxy-?25-?de (1-?methylpropyl) ?-?5-?oxo-avermectin A1a | 25-?Cyclohexyl-?4'-?O-?de (2, ?6-?dideoxy-?3-?O-?methyl-?α -?L-?arabino-?hexopyranosyl) ?-?5-?demethoxy-?25-?de (1-?methylpropyl) ?-?5-?oxo-avermectin A1a is an intermediate in synthesizing 22,23-Didehydro Selamectin (D439445), an impurity of Selamectin (S247990) which is a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals. Group: Biochemicals. Grades: Highly Purified. CAS No. 404578-37-6. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C43H60O11, Molecular Weight: 752.93. US Biological Life Sciences. | Worldwide |
| 25-?Cyclohexyl-?4'-?O-?de (2, ?6-?dideoxy-?3-?O-?methyl-?α -?L-?arabino-?hexopyranosyl) ?-?5-?O-?demethyl-?25-?de (1-?methylpropyl) ?-Avermectin A1a | 25-?Cyclohexyl-?4'-?O-?de (2, ?6-?dideoxy-?3-?O-?methyl-?α -?L-?arabino-?hexopyranosyl) ?-?5-?O-?demethyl-?25-?de (1-?methylpropyl) ?-Avermectin A1a is an intermediate in synthesizing 22,23-Didehydro Selamectin (D439445), an impurity of Selamectin (S247990) which is a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals. Group: Biochemicals. Grades: Highly Purified. CAS No. 165108-44-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C43H62O11, Molecular Weight: 754.95. US Biological Life Sciences. | Worldwide |
| 25-Cyclohexyl-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-oxo-avermectin A1a | 25-Cyclohexyl-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-oxo-avermectin A1a is an intermediate in synthesizing 4'-O-2,6-Dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl Selamectin (D440100), which s an impurity of Selamectin (S247990), a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals. Group: Biochemicals. Grades: Highly Purified. CAS No. 220119-16-4. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C50H74O14. US Biological Life Sciences. | Worldwide |
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