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Sesamin and sesamolin have been demonstrated to possess several bioactivities beneficial for human health. Excess generation of nitric oxide in lipopolysaccharide-stimulated rat primary microglia cells was significantly attenuated when they were pretreated with sesamin or sesamolin. The neuroprotective effect of sesamin and sesamolin was also observed in vivo using gerbils subjected to a focal cerebral ischemia induced by occlusion of the right common carotid artery and the right middle cerebral artery. Synonyms: (+)-5-[(1S,3aβ,4R,6aβ)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; (+)-5-[(1S,3aβ,4R,6aβ)-4-(1,3-Benzodioxole-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aβ,4β,6aβ)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aβ,4β,6aβ)-4-(1,3-Benzodioxole-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aR,4R,6aR)-4-(1,3-benzodioxol-5-yloxy)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aR,4R,6aR)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole. Grades: >98%. CAS No. 526-07-8. Molecular formula: C20H18O7. Mole weight: 370.36.
Sesamolin
Sesaminol, isolated from Sesamum indicum, has antioxidative activity, Sesaminol inhibits lipid peroxidation and shows neuroprotection effect. Sesaminol potently inhibits MAPK cascades by preventing phosphorylation of JNK, p38 MAPKs, and caspase-3 but not ERK-MAPK expression. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-[(1S,3aβ,4β,6aβ)-4-(1,3-Benzodioxole-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole. Product Category: Inhibitors. Appearance: White powder. CAS No. 526-07-8. Molecular formula: C20H18O7. Mole weight: 370.36. Purity: 0.98. IUPACName: 5-[[(3S,3aR,6R,6aR)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]oxy]-1,3-benzodioxole. Canonical SMILES: C1C2C(COC2OC3=CC4=C(C=C3)OCO4)C(O1)C5=CC6=C(C=C5)OCO6. Density: 1.418 g/ml. Product ID: ACM526078-1. Alfa Chemistry ISO 9001:2015 Certified.
Sesamolin
Sesamolin. Group: Biochemicals. Grades: Plant Grade. CAS No. 526-07-8. Pack Sizes: 10mg. Molecular Formula: C20H18O7, Molecular Weight: 370.35. US Biological Life Sciences.
Worldwide
Sesamolin
Sesamolin, isolated from Sesamum indicum , has antioxidative activity, Sesamolin inhibits lipid peroxidation and shows neuroprotection effect. Sesamolinl potently inhibits MAPK cascades by preventing phosphorylation of JNK , p38 MAPKs , and caspase-3 but not ERK-MAPK expression [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 526-07-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0809.
rac Enterodiol
A compound closely related to Enterolactone. A metabolite of sesame lignans (sesamin, sesamolin). Inhibits colonic cancer cell growth by inducing cell cycle arrest and apoptosis. Possible relationship between exposure and reduced risk of breast cancer. Group: Biochemicals. Alternative Names: (2R,3R)-rel-2,3-Bis[(3-hydroxyphenyl)methyl]-1,4-butanediol; (R*,R*)-(±)-2,3-Bis[(3-hydroxyphenyl)methyl]-1,4-butanediol. Grades: Highly Purified. CAS No. 77756-22-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
rac Enterodiol-d6
Isotope labelled rac Enterodiol, a compound closely related to Enterolactone (E558950). A metabolite of sesame lignans (sesamin, sesamolin). Inhibits colonic cancer cell growth by inducing cell cycle arrest and apoptosis. Possible relationship between exposure and reduced risk of breast cancer. Group: Biochemicals. Alternative Names: (2R,3R)-rel-2,3-Bis[(3-hydroxyphenyl)methyl]-1,4-butanediol-d6; (R*,R*)-(±)-2,3-Bis[(3-hydroxyphenyl)methyl]-1,4-butanediol-d6. Grades: Highly Purified. CAS No. 104411-12-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
rac Enterolactone
A metabolite of sesame lignans (sesamin, sesamolin). Inhibits colonic cancer cell growth by inducing cell cycle arrest and apoptosis. Possible relationship between exposure and reduced risk of breast cancer. Group: Biochemicals. Alternative Names: (3R,4R)-rel-Dihydro-3,4-bis[(3-hydroxyphenyl)methyl]-2(3H)-furanone; trans-Dihydro-3,4-bis[(3-hydroxyphenyl)methyl]-2(3H)-Furanone; HPMF; trans-2,3-Bis(3-hydroxybenzyl)-γ-butyrolactone. Grades: Highly Purified. CAS No. 78473-71-9. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
rac Enterolactone-d6
A labelled metabolite of sesame lignans (sesamin, sesamolin). Inhibits colonic cancer cell growth by inducing cell cycle arrest and apoptosis. Possible relationship between exposure and reduced risk of breast cancer. Group: Biochemicals. Alternative Names: Dihydro-3,4-bis[(3-hydroxyphenyl)methyl]-2(3H)-furanone-d6; trans-Dihydro-3,4-bis[(3-hydroxyphenyl)methyl]-2(3H)-Furanone-d6; HPMF-d6; trans-2,3-Bis(3-hydroxybenzyl)-γ-butyrolactone-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
(rac-Enterolactone)-O-glucuronide (Mixture of Diastereomers)
(rac-Enterolactone)-O-glucuronide is the oxidative metabolite of rac Enterolactone, a metabolite of sesame lignans (sesamin, sesamolin). Inhibits colonic cancer cell growth by inducing cell cycle arrest and apoptosis. Possible relationship between exposure and reduced risk of breast cancer. Synonyms: 3-[[Tetrahydro-4-[(3-hydroxyphenyl)methyl]-2-oxo-3-furanyl]methyl]phenyl-β-D-glucopyranosiduronic Acid; (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(3-((4-(3-hydroxybenzyl)-2-oxotetrahydrofuran-3-yl)methyl)phenoxy)tetrahydro-2H-pyran-2-carboxylic Acid. CAS No. 768385-57-5. Molecular formula: C24H26O10. Mole weight: 474.46.
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