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| Product | Description | |
|---|---|---|
| SGK1 Inhibitor | SGK1 Inhibitor is an inhibitor of serum- and glucocorticoid-regulated kinase 1 (SGK1) and SGK2 with IC50 values of 4.8 and 2.8 nM, respectively. It prevents phosphorylation of GSK3β in U2OS cells with IC50 value of 1.4 μM. Synonyms: SGK-1 Inhibitor; N-[4-(3-Amino-2H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,3-dichlorobenzenesulfonamide. Grades: ≥95%. CAS No. 1426214-51-8. Molecular formula: C17H12Cl2N6O2S. Mole weight: 435.29. |  |
| 10-DEBC hydrochloride | Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5uM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ~ 2-6uM) and induces apoptosis in rhabdomyosarcoma cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 925681-41-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C20H25N2OCl.HCl, Method for Determining. US Biological Life Sciences. |  Worldwide |
| 2-(4-Boronophenyl)-2-methylpropanoic Acid | 2-(4-Boronophenyl)-2-methylpropanoic Acid is a reagent used in the synthesis of serum and glucocorticoid-related kinase 1 (SGK1) inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1187209-18-2. Pack Sizes: 10mg, 25mg. Molecular Formula: C10H13BO4, Molecular Weight: 208.02. US Biological Life Sciences. | Worldwide |
| EMD638683 | EMD638683 is a highly selective SGK1 inhibitor, with an IC50 value of 3 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 1181770-72-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15193. |  |
| EMD638683 | EMD638683 is a potent SGK1 inhibitor with an IC50 of 3 μM. Synonyms: EMD638683; EMD 638683; EMD-638683. Grades: >98%. CAS No. 1181770-72-8. Molecular formula: C18H18F2N2O4. Mole weight: 364.34. | |
| EMD638683 R-Form | EMD638683 (R-Form) is a SGK1 inhibitor with an IC50 of < 300 nM. Synonyms: EMD 638683 (R-Form); EMD638683 (R-Form); EMD-638683 (R-Form). Grades:>98%. CAS No. 1184940-47-3. Molecular formula: C18H18F2N2O4. Mole weight: 364.34. | |
| EMD638683 S-Form | EMD638683 (S-Form) is a SGK1 inhibitor with an IC50 of >300 nM. Synonyms: EMD 638683 (S-Form); EMD638683 (S-Form); EMD-638683 (S-Form). Grades: >98%. CAS No. 1184940-46-2. Molecular formula: C18H18F2N2O4. Mole weight: 364.34. | |
| GSK 650394 | GSK 650394 is a novel SGK inhibitor with IC 50 of 62 nM and 103 nM for SGK1 and SGK2 in the SPA assay respectively. GSK 650394 also inhibits influenza virus replication. Uses: Scientific research. Group: Signaling pathways. CAS No. 890842-28-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15192. | |
| SGK1-IN-1 | SGK1-IN-1 is a highly active and selective inhibitor of SGK-1, with an IC50 of 1 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1279829-87-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18607. | |
| SI-113 | SI-113 is a SGK1 inhibitor, with an IC50 of 600 nM. SI113 induces autophagy[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1392816-46-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-117357. | |
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