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| Product | Description | |
|---|---|---|
| Silmitasertib | Silmitasertib (CX-4945) is an orally bioavailable, highly selective and potent CK2 inhibitor, with IC 50 values of 1 nM against CK2α and CK2α'. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CX-4945. CAS No. 1009820-21-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50855. |  |
| Silmitasertib | Silmitasertib is an orally bioavailable inhibitor of CK2 with potential antineoplastic activity. It inhibits proliferation in cancer cell lines overexpressing CK2. It suppresses survival and induces apoptosis of cancer stem cells including glioblastomas and acute myeloid leukemia cells. Synonyms: CX-4945; CX 4945; 5-((3-Chlorophenyl)amino)benzo[c][2, 6]naphthyridine-8-carboxylic acid. Grades: >98%. CAS No. 1009820-21-6. Molecular formula: C19H12ClN3O2. Mole weight: 349.774. |  |
| CX 4945 hydrochloride | CX 4945 hydrochloride is an orally bioactive and ATP-competitive casein kinase 2 (CK2) inhibitor. CX 4945 inhibits proliferation and migration in a panel of cancer cell lines which overexpresses CK2. Uses: Antitumor agent. Synonyms: CX 4945 hydrochloride; CX-4945 hydrochloride; CX4945 hydrochloride; Silmitasertib HCl; Silmitasertib hydrochloride. Grades: 98%. CAS No. 2108312-01-0. Molecular formula: C19H12ClN3O2.HCl. Mole weight: 386.23. | |
| CX-4945 sodium salt | CX-4945 (Silmitasertib) sodium salt is a potent and selective ATP-competitive small molecule protein kinase CK2 inhibitor with a Ki and an IC50 of 0.38 and 1 nM for recombinant human CK2α, respectively. Synonyms: Silmitasertib sodium salt; CX-4945 sodium salt; CX 4945 sodium salt; CX4945 sodium salt. Grades: >98%. CAS No. 1309357-15-0. Molecular formula: C19H11ClN3NaO2. Mole weight: 371.75. | |
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