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Silodosin (KAD 3213; KMD 3213) is a potent, selective and orally active α1A-adrenergic receptor (α1A-AR) blocker. Silodosin exhibits high affinity for α1A-AR ( K i =0.036 nM), over 162-fold and 50-fold than for α1B-AR and α1D-AR with K i values of 21 nM and 2.0 nM, respectively. Silodosin is an effective and well-tolerated agent, it can be used for the investigation of LUTS/BPH [1] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KAD 3213; KMD 3213. CAS No. 160970-54-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10122.
Silodosin b-D-glucuronide sodium salt
Silodosin b-D-glucuronide sodium salt is a pharmaceutical compound used in the biomedical industry for the treatment of benign prostatic hyperplasia (BPH). It is derived from Silodosin, a medication that selectively blocks alpha-1 adrenergic receptors in the prostate gland, relieving urinary symptoms associated with BPH. This sodium salt form enhances solubility and stability for drug formulation and delivery. Synonyms: 3-[7- (Aminocarbonyl) -2, 3-dihydro-5-[ (2R) -2-[[2-[2- (2, 2, 2-trifluoroethoxy) phenoxy]ethyl]amino]propyl]-1H-indol-1-yl]propyl b-D-glucopyranosiduronic acid monosodium salt. CAS No. 879292-24-7. Molecular formula: C31H40F3N3O10. Mole weight: 671.66.
Silodosin-d6
Silodosin-d6. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,3-Dihydro-1-(3-hydroxypropyl-d6)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carboxamide; (R)-1-(3-Hydroxypropyl-d6)-5-[2- [[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]indoline-7-carboxamide; KAD 3213-d6; KMD 3213-d6; Urief-d6. Product Category: Heterocyclic Organic Compound. CAS No. 1051374-52-7. Molecular formula: C25H26D6F3N3O4. Mole weight: 501.57. Purity: 0.96. IUPACName: 1-(1,1,2,2,3,3-hexadeuterio-3-hydroxypropyl)-5-[(2R)-2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethylamino]propyl]-2,3-dihydroindole-7-carboxamide. Canonical SMILES: CC(CC1=CC2=C(C(=C1)C(=O)N)N(CC2)CCCO)NCCOC3=CC=CC=C3OCC(F)(F)F. Product ID: ACM1051374527. Alfa Chemistry ISO 9001:2015 Certified.
Silodosin Dehydro Impurity
An impurity of Silodosin. Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Synonyms: 1- (3-Hydroxypropyl) -5-[ (2R) -2-[[2-[2- (2, 2, 2-trifluoroethoxy) phenoxy]ethyl]amino]propyl]-1H-indole-7-carboxamide; Dehydro Silodosin. Grades: > 95%. CAS No. 175870-21-0. Molecular formula: C25H30F3N3O4. Mole weight: 493.53.
Silodosin Glucuronide
An impurity of Silodosin. Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Synonyms: β-D-Glucopyranosiduronic acid, 3-[7- (aminocarbonyl) ?-2, ?3-dihydro-5-[ (2R) ?-2-[[2-[2- (2, ?2, ?2-trifluoroethoxy) ?phenoxy]?ethyl]?amino]?propyl]?-1H-indol-1-yl]?propyl. Grades: > 95%. CAS No. 879396-70-0. Molecular formula: C31H40F3N3O10. Mole weight: 671.66.
Silodosin impurity 1
Silodosin impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H32F3N3O5. Mole Weight: 511.54. Catalog: APB11440.
Silodosin impurity 2
Silodosin impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 160969-01-7. Molecular Formula: C12H13F3O4. Mole Weight: 278.23. Catalog: APB160969017.
Silodosin Impurity 2 HCl (Nitrile Impurity)
An impurity of Silodosin. Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Synonyms: 1H-Indole-7-carbonitrile, 2, ?3-dihydro-1- (3-hydroxypropyl) ?-5-[ (2R) ?-2-[[2-[2- (2, ?2, ?2-trifluoroethoxy) ?phenoxy]?ethyl]?amino]?propyl]?-, hydrochloride (1:1). Grades: > 95%. CAS No. 1889255-72-4. Molecular formula: C25H30F3N3O3. HCl. Mole weight: 477.53 36.46.
Silodosin impurity 3
Silodosin impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2182279-45-2. Molecular Formula: C25H32F3N3O4. Mole Weight: 495.54. Catalog: APB2182279452.
Silodosin Impurity 3 (Dimer Impurity)
An impurity of Silodosin. Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Grades: > 95%. Molecular formula: C35H41F6N3O6. HCl. Mole weight: 713.72 36.46.
Silodosin impurity 4
Silodosin impurity 4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H29F3N4O4. Mole Weight: 506.53. Catalog: APB11442.
Silodosin Impurity 5
A metabolite or degradation Silodosin. Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Synonyms: Silodosin N-Oxide. Grades: > 95%. Molecular formula: C25H32F3N3O5. Mole weight: 511.55.
Silodosin Impurity 6
An impurity of Silodosin. Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Synonyms: (R) -1-[3- (Acetyloxy) propyl]-2, 3-dihydro-5-[2-[[2-[2- (2, 2, 2-trifluoroethoxy) phenoxy]ethyl]amino]propyl]-1H-Indole-7-carboxamide; O-Acetyl Silodosin. Grades: > 95%. CAS No. 160970-86-5. Molecular formula: C27H34F3N3O5. Mole weight: 537.58.
Silodosin Impurity 7
A metabolite of Silodosin, Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Synonyms: (R) -5- (2- ( (2- (2- (2, 2, 2-Trifluoroethoxy) phenoxy) ethyl) amino) propyl) indoline-7-carboxamide; Deshydroxypropyl Silodosin. Grades: > 95%. Molecular formula: C22H26F3N3O3. Mole weight: 437.47.
Silodosin Impurity 8
A metabolite of Silodosin, Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Synonyms: Benzoic acid, 4-methyl-, 3-[7-cyano-2, ?3-dihydro-5-[ (2R) ?-2-[[2-[2- (2, ?2, ?2-trifluoroethoxy) ?phenoxy]?ethyl]?amino]?propyl]?-1H-indol-1-yl]?propyl ester. Grades: > 95%. CAS No. 1638212-09-5. Molecular formula: C33H36F3N3O4. Mole weight: 595.65.
Silodosin Metabolite
An impurity of Silodosin. Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Synonyms: 1H-Indole-1-propanoic acid, 7- (aminocarbonyl) ?-2, ?3-dihydro-5-[ (2R) ?-2-[[2-[2- (2, ?2, ?2-trifluoroethoxy) ?phenoxy]?ethyl]?amino]?propyl]?-; 7- (Aminocarbonyl) -2, 3-dihydro-5-[ (2R) -2-[[2-[2- (2, 2, 2-trifluoroethoxy) phenoxy]ethyl]amino]propyl]-1H-indole-1-propanoic acid. Grades: > 95%. CAS No. 1357252-79-9. Molecular formula: C25H30F3N3O5. Mole weight: 509.52.
Silodosin Related Impurity
An intermediate in the synthesis of (R)-Silodosin. Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Synonyms: 5-(2-Aminopropyl)-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile; 3-(7-Cyano-5-(2-(amino)propyl)indolin-1-yl)propyl Benzoate. Grades: > 95%. CAS No. 1338365-54-0. Molecular formula: C22H25N3O2. Mole weight: 363.46.
Silodosin (R-isomer)
Cas No. 160970-54-7.
Silodosin S-Isomer
An isomer of Silodosin, which is used in the treatment of the symptoms of an enlarged prostate (benign prostatic hyperplasia; BPH) in men. Synonyms: Silodosin (S)-Isomer; (S)-Silodosin; 1- (3-Hydroxypropyl) -5-[ (2S) - ({2-[2-[2- (2, 2, 2-trifluoroethoxy) phenoxy]ethyl}amino) propyl]indoline-7-carboxamide; (S) -1- (3-Hydroxypropyl) -5- (2- ( (2- (2- (2, 2, 2-trifluoroethoxy) phenoxy) ethyl) amino) propyl) indoline-7-carboxamide. CAS No. 2182279-45-2. Molecular formula: C25H32F3N3O4. Mole weight: 495.53.
1,2-Dehydro Dehydroxypropyl Silodosin
1,2-Dehydro Dehydroxypropyl Silodosin is an impuriy of Silodosin (S465000), which is an α1a-adrenoceptor antagonist used in treatment of benign prostatic hypertrophy. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C22H24F3N3O3, Molecular Weight: 435.44. US Biological Life Sciences.
N-2-[2- (2, 2, 2-Trifluoroethoxy) phenoxy]ethylsilodosin is an impurity of Silodosin, which is an α1a-adrenoceptor antagonist. Synonyms: N-2-[2- (2, 2, 2-Trifluoroethoxy) phenoxy]ethylsilodosin; 1453221-45-8; 5-[2-[bis[2-[2- (2, 2, 2-trifluoroethoxy) phenoxy]ethyl]amino]propyl]-1- (3-hydroxypropyl) -2, 3-dihydroindole-7-carboxamide; Silodosin Dimer Impurity; BCP32812; Silodosin impurity 19; N-2-[2- (2, 2, 2-Trifluoroethoxy) phenoxy]ethylsilodosin. CAS No. 1453221-45-8. Molecular formula: C35H41F6N3O6. Mole weight: 713.718.
Nitroso Silodosin
Nitroso Silodosin. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H31F3N4O5. Mole Weight: 524.54. Catalog: APB11441.
N-tert-Butyloxycarbonyl Dihydro Silodosin
N-tert-Butyloxycarbonyl Dihydro Silodosin is a protected Dihydro Silodosin (D446450), used in the preparation of α1-adrenaline receptor blockers. Group: Biochemicals. Alternative Names: [ (1R) -2-[7- (Aminocarbonyl) -1- (3-hydroxypropyl) -1H-indol-5-yl]-1-methylethyl][2-[2- (2, 2, 2-trifluoroethoxy) phenoxy]ethyl]-carbamic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 239463-80-0. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
N-tert-Butyloxycarbonyl Silodosin
N-tert-Butyloxycarbonyl Silodosin is a protected Silodosin (S465000), an α1a-adrenoceptor antagonist. Group: Biochemicals. Alternative Names: N-[ (1R) -2-[7- (Aminocarbonyl) -2, 3-dihydro-1- (3-hydroxypropyl) -1H-indol-5-yl]-1-methylethyl]-N-[2-[2- (2, 2, 2-trifluoroethoxy) phenoxy]ethyl]-carbamic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 160970-07-0. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
rac-Silodosin
An impurity of Silodosin. Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Synonyms: 1H-Indole-7-carboxamide, 2, ?3-dihydro-1- (3-hydroxypropyl) ?-5-[2-[[2-[2- (2, ?2, ?2-trifluoroethoxy) ?phenoxy]?ethyl]?amino]?propyl]?-; 2, 3-Dihydro-1- (3-hydroxypropyl) -5-[2-[[2-[2- (2, 2, 2-trifluoroethoxy) phenoxy]ethyl]amino]propyl]-1H-indole-7-carboxamide. Grades: > 95%. CAS No. 160970-64-9. Molecular formula: C25H32F3N3O4. Mole weight: 495.53.
(S)-Silodosin (Silodosin Impurity 4)
A stereoisomer of silodosin. Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Synonyms: (S) -1- (3-Hydroxypropyl) -5- (2- ( (2- (2- (2, 2, 2-trifluoroethoxy) phenoxy) ethyl) amino) propyl) indoline-7-carboxamide. Grades: > 95%. Molecular formula: C25H32F3N3O4. Mole weight: 495.55.
1-[3-(benzoyloxy)propyl]-2,3-dihydro-5-(2-oxopropyl)-1H-Indole-7-carbonitrile can be used to synthesize silodosin (S465005) which is a medication for treating the symptoms of benign prostatic hyperplasia. It can also be utilized by various ω-transaminases (ωTAs) to form silodosin amine intermediate. Group: Biochemicals. Grades: Highly Purified. CAS No. 350797-57-8. Pack Sizes: 250mg, 1g. Molecular Formula: C22H22N2O3, Molecular Weight: 362.42. US Biological Life Sciences.
1-[3-(Benzyloxy)propyl]-5-formylindoline-7-carbonitrile is an intermediate of Silodosin (S465000) which is an α1a-adrenoceptor antagonist and used in the treatment of benign prostatic hypertophy. Group: Biochemicals. Grades: Highly Purified. CAS No. 1375180-30-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C20H20N2O2, Molecular Weight: 320.38. US Biological Life Sciences.
1-Acetyl-5-(2-aminopropyl)indoline-7-carbonitrile is an intermediate in the synthesis of Silodosin (S465000), an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy. Group: Biochemicals. Grades: Highly Purified. CAS No. 175837-01-1. Pack Sizes: 250mg, 2.5g. Molecular Formula: C14H17N3O. US Biological Life Sciences.
2- (2- (2, 2, 2-Trifluoroethoxy) phenoxy) acetaldehyde is an intermediate in the synthesis of N-2-[2- (2, 2, 2-Trifluoroethoxy) phenoxy]ethylsilodosin (T790140), which is an impurity in the synthesis of Silodosin (S465000), an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy. Group: Biochemicals. Grades: Highly Purified. CAS No. 1269801-73-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C10H9F3O3. US Biological Life Sciences.
2-[2- (2, 2, 2-Trifluoroethoxy) phenoxy]ethyl Methanesulfonate is an intermediate of Silodosin (S465000) which is an α1a-adrenoceptor antagonist and used in the treatment of benign prostatic hypertophy. Group: Biochemicals. Grades: Highly Purified. CAS No. 160969-03-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C11H13F3O5S, Molecular Weight: 314.279999999999. US Biological Life Sciences.
2-[[2- (2, 2, 2-Trifluoroethoxy) phenoxy]methyl]-1, 3-dioxolane is an intermediate in the synthesis of N-2-[2- (2, 2, 2-Trifluoroethoxy) phenoxy]ethylsilodosin (T790140), which is an impurity in the synthesis of Silodosin (S465000), an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy. Group: Biochemicals. Grades: Highly Purified. CAS No. 1269801-74-2. Pack Sizes: 50mg, 100mg. Molecular Formula: C12H13F3O4. US Biological Life Sciences.
3-(7-Cyano-5-(2-nitropropyl)indolin-1-yl)propyl Benzoate is used in the preparation of Silodosin (S465000), an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy. Group: Biochemicals. Grades: Highly Purified. CAS No. 350797-56-7. Pack Sizes: 5g, 25g. Molecular Formula: C22H23N3O4. US Biological Life Sciences.
Worldwide
3-(Benzyloxy)propyl 4-Toluenesulfonate
3-(Benzyloxy)propyl 4-Toluenesulfonate is used as a reagent in the synthesis of Silodosin (S465000); an antidysuria drug. 3-(Benzyloxy)propyl 4-Toluenesulfonate is also used as a reagent in the preparation of aryloxyalkyl derivatives of adenine which have antiviral activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 120758-24-9. Pack Sizes: 1g, 5g. Molecular Formula: C17H20O4S, Molecular Weight: 320.399999999999. US Biological Life Sciences.
Worldwide
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