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| Product | Description | |
|---|---|---|
| Sirolimus isoform 2 | Sirolimus isoform 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C38H57NO11. Mole Weight: 703.87. Catalog: APB09601. |  |
| Sirolimus isoform 3 | Sirolimus isoform 3. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C52H81NO13. Mole Weight: 928.21. Catalog: APB09600. | |
| Sirolimus Liposome | Sirolimus, a metabolite of AYBP44 (streptomyces hygroscopicus), is not only a low-toxicity antibiotic but also a novel immunosuppressant. This product is a pre-formulated liposome with sirolimus. It is only for research purposes. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. |  |
| Sirolimus trione isomer | Sirolimus trione isomer. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C51H79NO13. Mole Weight: 914.19. Catalog: APB09602. | |
| 27-O-Desmethyl Rapamycin (27-O-Desmethyl Sirolimus) | A metabolite of Rapamycin. Rapamycin is a macrolide compound. It inhibits activation of T cells and B cells by reducing the production of interleukin-2. Rapamycin can be used to coat coronary stents and prevent organ transplant rejection. Grades: > 95%. Molecular formula: C50H77NO13. Mole weight: 900.17. |  |
| Everolimus Impurity 9-O-Hydroxyethyl sirolimus (009-96) | Everolimus Impurity 9-O-Hydroxyethyl sirolimus (009-96). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus Impurity 9-O-Hydroxyethyl sirolimus(009-96). Molecular Formula: C53H83NO14. Mole Weight: 958.22. Catalog: APB05424. | |
| Rapamycin Impurity 4 (Sirolimus-31,42-Diester Impurity) | An impurity of Rapamycin. Rapamycin is a macrolide compound. It inhibits activation of T cells and B cells by reducing the production of interleukin-2. Rapamycin can be used to coat coronary stents and prevent organ transplant rejection. Grades: > 95%. Molecular formula: C61H95NO19. Mole weight: 1146.43. | |
| Rapamycin, seco, Sodium Salt (FRAP, mTOR Inhibitor, Sirolimus) | A metabolite of Sirolimus. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. |  Worldwide |
| Rapamycin (Sirolimus) | Cas No. 53123-88-9. | |
| 28-Epirapamycin | 28-Epirapamycin is an epimer of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, RapaNui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. Group: Biochemicals. Grades: Highly Purified. CAS No. 253431-35-5. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C51H79NO13. US Biological Life Sciences. | Worldwide |
| 28-O-Methyl-rapamycin | 28-O-Methyl-rapamycin is a derivative of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, RapaNui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. Group: Biochemicals. Grades: Highly Purified. CAS No. 159351-88-9. Pack Sizes: 1mg. Molecular Formula: C52H81NO13. US Biological Life Sciences. | Worldwide |
| (2S)?-1-?[2-?[(2R, ?3R, ?6S)?-?6-?[(2S, ?3E, ?5E, ?7E, ?9S, ?11R)?-?2, ?13-?Dimethoxy-?3, ?9, ?11-?trimethyl-?12-?oxo-?3, ?5, ? 7-? tridecatrien-? 1-? yl] ? tetrahydro-? 2-? hydroxy-? 3-? methyl-? 2H-? pyran-? 2-? yl] ? -? 2-? oxoacetyl] ? -? 2-? piperidinecarboxylic Acid | (2S)?-1-?[2-?[(2R, ?3R, ?6S)?-?6-?[(2S, ?3E, ?5E, ?7E, ?9S, ?11R)?-?2, ?13-?Dimethoxy-?3, ?9, ?11-?trimethyl-?12-?oxo-?3, ?5, ? 7-? tridecatrien-? 1-? yl] ? tetrahydro-? 2-? hydroxy-? 3-? methyl-? 2H-? pyran-? 2-? yl] ? -? 2-? oxoacetyl] ? -? 2-? piperidinecarboxylic Acid is an impurity of Sirolimus (R124000) which is an immunosuppressant drug used to prevent rejection in organ transplantation. Group: Biochemicals. Grades: Highly Purified. CAS No. 147438-30-0. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C32H49NO9, Molecular Weight: 591.73. US Biological Life Sciences. | Worldwide |
| (2S)?-1-?[2-?[(2R, ?3R, ?6S)?-?6-?[(2S, ?3E, ?5E, ?7E, ?9S, ?11R)?-?2, ?13-?Dimethoxy-?3, ?9, ?11-?trimethyl-?12-?oxo-?3, ?5, ? 7-? tridecatrien-? 1-? yl] ? tetrahydro-? 2-? hydroxy-? 3-? methyl-? 2H-? pyran-? 2-? yl] ? -? 2-? oxoacetyl] ? -? 2-? piperidinecarboxylic Acid-d3 | (2S)?-1-?[2-?[(2R, ?3R, ?6S)?-?6-?[(2S, ?3E, ?5E, ?7E, ?9S, ?11R)?-?2, ?13-?Dimethoxy-?3, ?9, ?11-?trimethyl-?12-?oxo-?3, ?5, ? 7-? tridecatrien-? 1-? yl] ? tetrahydro-? 2-? hydroxy-? 3-? methyl-? 2H-? pyran-? 2-? yl] ? -? 2-? oxoacetyl] ? -? 2-? piperidinecarboxylic Acid-d3 is labelled (2S)?-1-?[2-?[(2R, ?3R, ?6S)?-?6-?[(2S, ?3E, ?5E, ?7E, ?9S, ?11R)?-?2, ?13-?Dimethoxy-?3, ?9, ?11-?trimethyl-?12-?oxo-?3, ?5, ? 7-? tridecatrien-? 1-? yl] ? tetrahydro-? 2-? hydroxy-? 3-? methyl-? 2H-? pyran-? 2-? yl] ? -? 2-? oxoacetyl] ? -? 2-? piperidinecarboxylic Acid (D461585) which is an impurity of Sirolimus (R124000) which is an immunosuppressant drug used to prevent rejection in organ transplantation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C32H46D3NO9, Molecular Weight: 594.75. US Biological Life Sciences. | Worldwide |
| 7-O-Demethyl rapamycin | 7-O-Demethyl rapamycin, a derivative of Rapamycin (HY-10219), has antifungal activity and immunosuppressant properties. 7-O-Demethyl rapamycin has useful tumor cell growth-inhibiting activity. Group: Inhibitors. Alternative Names: 7-O-Demethyl Cypher; 7-O-Demethyl Rapammune; 7-O-Demethyl Sirolimus. CAS No. 151519-50-5. Molecular formula: C50H77NO13. Mole weight: 900.15. Appearance: Solid. Purity: 0.96. IUPACName: 7-O-Demethyl Rapamycin. Canonical SMILES: CC1CCC2CC (C (=CC=CC=CC (CC (C (=O)C (C (C (=CC (C (=O)CC (OC (=O)C3CCCCN3C (=O)C (=O)C1 (O2)O)C (C)CC4CCC (C (C4)OC)O)C)C)O)OC)C)C)C)O. Catalog: ACM151519505. |  |
| 7-O-Demethyl Rapamycin | Rapamycin metabolite. Group: Biochemicals. Alternative Names: 7-O-Demethyl Cypher; 7-O-Demethyl Rapammune; 7-O-Demethyl Sirolimus. Grades: Highly Purified. CAS No. 151519-50-5. Pack Sizes: 1mg. Molecular Formula: C??H??NO??, Molecular Weight: 900.15. US Biological Life Sciences. | Worldwide |
| 7-O-Desmethyl Rapamycin | A metabolite of Rapamycin. Rapamycin is a macrolide compound. It inhibits activation of T cells and B cells by reducing the production of interleukin-2. Rapamycin can be used to coat coronary stents and prevent organ transplant rejection. Synonyms: 7-O-Demethyl Cypher; 7-O-Demethyl Rapammune; 7-O-Demethyl Sirolimus. Grades: > 95%. CAS No. 151519-50-5. Molecular formula: C50H77NO13. Mole weight: 900.17. | |
| Everolimus | Everolimus is an immunosuppressant analog of rapamycin (sirolimus) and inhibits growth factor-mediated proliferation of hematopoietic and nonhematopoietic cells. Everolimus shows a potent inhibitory effect on posttransplant lymphoproliferative disorder (PTLD)-derived cells in vitro and in vivo, in a dose range that can prevent allograft rejection, and may demonstrate activity in both the prevention and treatment of PTLDs in transplant patients. Group: Biochemicals. Alternative Names: Afinitor, Certican, RAD-001, Zortress; 40-O- (2-Hydroxyethyl) rapamycin; 42-O-(2-Hydroxy)ethyl Rapamycin; RAD; RAD 001; SDZ-RAD; XIENCE V. Grades: Highly Purified. CAS No. 159351-69-6. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Pimecrolimus (Elidel, SDZ-ASM-981, D05480) | Pimecrolimus, a rapamycin (sirolimus) derivative, is a cell-selective inhibitor of inflammatory cytokines developed for the treatment of inflammatory skin diseases, such as allergic contact dermatitis, atopic dermatitis, plaque-type psoriasis, and irritant contact dermatitis. It reduces the production of inflammatory cytokines in T cells and mast cells and inhibits the release of preformed inflammatory mediators from mast cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 137071-32-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Rapamycin | Rapamycin is an mTOR inhibitor immunosuppressant and kinase inhibitor with both antifungal and antineoplastic properties. It selectively inhibits the transcriptional activation of cytokines. Uses: Antifungal and antineoplastic agent. Synonyms: Sirolimus; (-)-Rapamycin; AY 22989; AY-22989; I-2190A; NSC 226080; RAPA; RAP; RPM; SLM; WY-090217; Everolimus EP Impurity A. Grades: >98%. CAS No. 53123-88-9. Molecular formula: C51H79NO13. Mole weight: 914.19. | |
| Rapamycin | Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC 50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1 [1]. Rapamycin is an autophagy activator, an immunosuppressant [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Sirolimus; AY-22989. CAS No. 53123-88-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 2 g; 5 g. Product ID: HY-10219. |  |
| Rapamycin | Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant. Group: Inhibitors. Alternative Names: 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine solution. CAS No. 53123-88-9. Molecular formula: C51H79NO13. Mole weight: 914.18. Appearance: Powder. Purity: 0.98. IUPACName: (1R, 9S, 12S, 15R, 16E, 18R, 19R, 21R, 23S, 24E, 26E, 28E, 30S, 32S, 35R)-1, 18-dihydroxy-12-[(2R)-1-[(1S, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19, 30-dimethoxy-15, 17, 21, 23, 29, 35-hexamethyl-11, 36-dioxa-4-azatricyclo[30.3.1.04, 9]hexatriaconta-16, 24, 26, 28-tetraene-2, 3, 10, 14, 20-pentone. Canonical SMILES: C[C@@H]1CC[C@H]2C[C@@H] (/C (=C/C=C/C=C/[C@H] (C[C@H] (C (=O)[C@@H] ([C@@H] (/C (=C/[C@H] (C (=O)C[C@H] (OC (=O)[C@@H]3CCCCN3C (=O)C (=O)[C@@]1 (O2)O)[C@H] (C)C[C@@H]4CC[C@H] ([C@@H] (C4)OC)O)C)/C)O)OC)C)C)/C)OC. Density: 1.035 g/ml. Catalog: ACM53123889. | |
| Rapamycin-d3 | Rapamycin-d 3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC 50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant [1] [2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Sirolimus-d3; AY-22989-d3. CAS No. 392711-19-2. Pack Sizes: 500 μg; 1 mg. Product ID: HY-10219S. | |
| Zotarolimus | Zotarolimus (also known as ABT-578) is an analogue of rapamycin (sirolimus) that was designed to have a shorter in vivo half-life than rapamycin. Zotarolimus was found to be comparable in potency for inhibiting in vitro proliferation of both rat and human T cells and mechanistically similar to sirolimus in having high-affinity binding to the immunophilin FKBP12. Zotarolimus is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier. Group: Biochemicals. Alternative Names: 40-epi-(N1-Tetrazolyl)-rapamycin; ABT-578; KY 12420. Grades: Highly Purified. CAS No. 221877-54-9. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
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