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Sitafloxacin, a new-generation, broad-spectrum oral fluoroquinolone that is very active against many Gram-positive, Gram-negative and anaerobic clinical isolates, including strains resistant to other fluoroquinolones, was recently approved in Japan for the treatment of respiratory and urinary tract infections. In terms of clinical efficacy, oral sitafloxacin was noninferior to oral levofloxacin in the treatment of community-acquired pneumonia or an infectious exacerbation of chronic respiratory tract disease, noninferior to oral tosufloxacin in the treatment of community-acquired pneumonia, and noninferior to oral levofloxacin in the treatment of complicated urinary tract infections, according to the results of randomized, double-blind, multicentre, noninferiority trials. Noncomparative studies demonstrated the efficacy of oral sitafloxacin in otorhinolaryngological infections, urethritis in men, C. trachomatis-associated cervicitis in women and odontogenic infections. Synonyms: 7-((S)-7-amino-5-azaspiro[24]heptan-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; DU 6859; DU-6859; DU6859; DU 6859A; DU-6859A; DU6859A; Sitafloxacin; Sitafloxacin hydrate, Sitafloxacin anhydrous, Trade name: Gracevit. Grades: >98%. CAS No. 127254-12-0. Molecular formula: C19H18ClF2N3O3. Mole weight: 409.81.
Sitafloxacin
Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DU6859a. CAS No. 127254-12-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0395.
Sitafloxacin Dechloro Impurity
An impurity of Sitafloxacin. Sitafloxacin is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer. Synonyms: 3-Quinolinecarboxylic acid, 7-[(7S)?-7-amino-5-azaspiro[2.4]?hept-5-yl]?-6-fluoro-1-[(1R,?2S)?-2-fluorocyclopropyl]?-1,?4-dihydro-4-oxo-; 7-[(7S)-7-Amino-5-azaspiro[2.4]hept-5-yl]-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid. Grades: > 95%. CAS No. 500569-52-8. Molecular formula: C19H19F2N3O3. Mole weight: 375.37.
Sitafloxacin hydrate
Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic ( antibiotic ) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DU6859a hydrate. CAS No. 163253-35-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0395C.
Sitafloxacin Hydrate
Sitafloxacin is active against methicillin-resistant staphylococci, Streptococcus pneumoniae and other streptococci with reduced susceptibility to levofloxacin and other quinolones and enterococci. Synonyms: DU-6859a; DU 6859a; DU6859a. Grades: >98%. CAS No. 163253-35-8. Molecular formula: C19H20ClF2N3O4. Mole weight: 427.8.
Sitafloxacin Impurity 1
An impurity of Sitafloxacin. Sitafloxacin is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer. Grades: > 95%. Molecular formula: C16H16FN3O3. Mole weight: 317.32.
Sitafloxacin Impurity 2
An impurity of Sitafloxacin. Sitafloxacin is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer. Grades: > 95%. Molecular formula: C19H19F2N3O4. Mole weight: 391.38.
Sitafloxacin Impurity 27
Sitafloxacin Impurity 27. Uses: For analytical and research use. Group: Impurity standards. CAS No. 101513-77-3. Molecular formula: C7H2ClF3O2. Mole weight: 210.54. Catalog: APB101513773.
Sitafloxacin isomer II
Sitafloxacin isomer II. Group: Biochemicals. Grades: Highly Purified. CAS No. 127199-06-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. US Biological Life Sciences.
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Sitafloxacin isomer III (RRS)
An isomer of Sitafloxacin. Sitafloxacin is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer. Synonyms: 7-((R)-7-amino-5-azaspiro[2.4]heptan-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 3-Quinolinecarboxylicacid,7-[(7R)-7-amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-; 7-[(7R)?-7-amino-5-azaspiro[2.4]?hept-5-yl]?-8-chloro-6-fluoro-1-[(1R,?2S)?-2-fluorocyclopropyl]?-1,?4-dihydro-4-oxo-3-Quinolinecarboxylic acid. CAS No. 127254-10-8. Molecular formula: C19H18ClF2N3O3. Mole weight: 409.818.
Sitafloxacin isomer I (SSR)
Sitafloxacin isomer I (SSR). Group: Biochemicals. Grades: Highly Purified. CAS No. 127254-11-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. US Biological Life Sciences.
Worldwide
Sitafloxacin Sesquihydrate
Antibacterial. Group: Biochemicals. Alternative Names: 7-[(7S)-7-Amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Hydrate. Grades: Highly Purified. CAS No. 163253-35-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
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