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Sporidesmolide complex It is a family of five closely related cyclic depsipeptides. Sporidesmolide complex contains three dominant components, I, II and V, with less quantities of the more polar III and only traces of sporidesmolide IV. Grades: >95% by HPLC. CAS No. 11113-90-9. Molecular formula: C34H60N4O8 (for sporidesmolide II). Mole weight: 652.86 (for sporidesmolide II). BOC Sciences 5
Sporidesmolide I It is the most polar of N-methyl analogues belonging to the hexadepsipeptide sporidesmolide complex. It has no activity against a variety of bacteria and fungi. It is a depsipeptide originally isolated from S. bakeri. Synonyms: Sporidesmolide 1; cyclo[(2S)-2-hydroxy-3-methylbutanoyl-D-valyl-D-leucyl-(2S)-2-hydroxy-3-methylbutanoyl-L-valyl-N-methyl-L-leucyl]; cyclo[D-leucyl-N-oxa-L-valyl-L-valyl-N-methyl-L-leucyl-N-oxa-L-valyl-D-valyl]; cyclo[D-Leu-OVal-Val-N(Me)Leu-OVal-D-Val]. Grades: >95% by HPLC. CAS No. 2900-38-1. Molecular formula: C33H58N4O8. Mole weight: 638.84. BOC Sciences 5
Sporidesmolide II It is the most abundant of N-methyl analogue belonging to the hexadepsipeptide sporidesmolide complex. It is a cyclic depsipeptide originally isolated from P. chartarum. Synonyms: cyclo[D-Leu-OVal-Val-N(Me)Leu-OVal-D-aIle]; cyclo[D-leucyl-N-oxa-L-valyl-L-valyl-N-methyl-L-leucyl-N-oxa-L-valyl-D-alloisoleucyl]; (3S,6S,9S,12R,15R,18S)-15-((S)-sec-butyl)-3,12-diisobutyl-6,9,18-triisopropyl-4-methyl-1,10-dioxa-4,7,13,16-tetraazacyclooctadecane-2,5,8,11,14,17-hexaone. Grades: >95% by HPLC. CAS No. 3200-75-7. Molecular formula: C34H60N4O8. Mole weight: 652.86. BOC Sciences 5
Sporidesmolide III It is the only non-N-methylated analogue of the hexadepsipeptide sporidesmolide complex. It is the demethyl analogue of sporidesmolide I. It is a cyclodepsipeptide originally isolated from P. chartarum. Synonyms: Cyclo(3-methyl-L-2-hydroxybutanoyl-D-valyl-D-leucyl-3-methyl-L-2-hydroxybutanoyl-L-valyl-L-leucyl); cyclo[D-Leu-OVal-Val-Leu-OVal-D-Val]; cyclo[D-leucyl-N-oxa-L-valyl-L-valyl-L-leucyl-N-oxa-L-valyl-D-valyl]. Grades: >95% by HPLC. CAS No. 1803-67-4. Molecular formula: C32H56N4O8. Mole weight: 624.81. BOC Sciences 5
Sporidesmolide V It is the most non-polar of the N-methyl analogue belonging to the hexadepsipeptide sporidesmolide complex. It is a cyclodepsipeptide fungal metabolite originally isolated from Pithomyces chartarum. Synonyms: cyclo[D-Leu-OLeu-Val-N(Me)Leu-OVal-D-aIle]; cyclo[D-leucyl-N-oxa-L-leucyl-L-valyl-N-methyl-L-leucyl-N-oxa-L-valyl-D-alloisoleucyl]; cyclo(D-alloisoleucyl-D-leucyl-4-methyl-L-2-hydroxypentanoyl-L-valyl-N-methyl-L-leucyl-3-methyl-L-2-hydroxybutanoyl). Grades: >95% by HPLC. CAS No. 127072-57-5. Molecular formula: C35H62N4O8. Mole weight: 666.89. BOC Sciences 5

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