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100g Pack Size. Group: Organics, Research Organics & Inorganics. Formula: C8H14O4. CAS No. 505-48-6. Prepack ID 16326556-100g. Molecular Weight 174.19. See USA prepack pricing.
Subericacid
500g Pack Size. Group: Organics, Research Organics & Inorganics. Formula: C8H14O4. CAS No. 505-48-6. Prepack ID 16326556-500g. Molecular Weight 174.19. See USA prepack pricing.
Subericacid
Subericacid (Octanedioic acid) is an orally active crystalline dibasic acid. Subericacid activates the Akt signaling pathway and regulates the expression of molecules related to the TGF-β and MAPK signaling pathways. Subericacid inhibits skin dryness [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Octanedioic acid. CAS No. 505-48-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g; 5 g. Product ID: HY-W015300.
SubericAcid
SubericAcid is used in the preparation of reduction-sensitive micelles affecting their cellular uptake. This has potential application in delivery of anticancer drugs. It is also used in the fluorescent detection of amidinium-carboxylate and amidinium formation. Group: Biochemicals. Alternative Names: Octanedioic Acid; SubericAcid; 1,6-Dicarboxyhexane; 1,6-Hexanedicarboxylic Acid; 1,8-Octanedioic Acid; Cork Acid; Hexa methyl enedicarboxylic Acid; NSC 25952; NSC 53777. Grades: Highly Purified. CAS No. 505-48-6. Pack Sizes: 10g. US Biological Life Sciences.
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Subericacid 99+% (GC)
Subericacid 99+% (GC). Group: Biochemicals. Grades: GC. Pack Sizes: 25g, 100g, 250g, 1Kg, 2.5Kg. US Biological Life Sciences.
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SubericAcid Bis(3-sulfo-N-hydroxysuccinimide ester)-d4 Disodium Salt
Subericacid dimethyl ester. Group: Biochemicals. Alternative Names: Dimethyl suberate; Octanedioic acid dimethyl ester. Grades: Highly Purified. CAS No. 1732-09-8. Pack Sizes: 50g, 100g, 250g. US Biological Life Sciences.
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Subericacid dimethyl ester 99+%
Subericacid dimethyl ester 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 1732-09-8. Pack Sizes: 5g, 25g, 100g, 250g. US Biological Life Sciences.
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Subericacid monomethyl ester
Subericacid monomethyl ester. Group: Biochemicals. Grades: Highly Purified. CAS No. 3946-32-5. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C9H16O4. US Biological Life Sciences.
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SubericAcid Monomethyl Ester
SubericAcid Monomethyl Ester. CAS No: 3946-32-5
Sarchem Laboratories New Jersey NJ
SBHA (Suberohydroxamic acid, Suberic bis-hydroxamic acid, N, N'-dihydroxyoctane diamide)
SBHA is a competitive histone deacetylase (HDAC) inhibitor that has been shown to inhibit HDAC1 (IC50=0.25uM) and HDAC3 (IC50=0.30uM). SBHA causes cell differentiation, cell cycle arrest, or apoptosis. SBHA also enhances cytotoxicity induced by Oxaliplatin in the colorectal cancer cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 38937-66-5. Pack Sizes: 50mg, 250mg. US Biological Life Sciences.
BS3 Crosslinker is a water-soluble, homobifunctional protein crosslinker. Group: Biochemicals. Alternative Names: Bis-sulfosuccinimidyl Suberate, BS3, Sulfo-DSS, Bis-sulfo-succinimidyl Suberatebissulfosuccin imidyl Suberate, Sulfo-DSS, SubericAcid sulfoNHS Ester, BSSS, BS3-d0, Sodium 1, 1- (octanedioylbis (oxy))bis (2, 5-dioxopyrrolidine-3-sulfonate), BS3 Protein Crosslinker. Grades: Purified. CAS No. 82436-77-9. Pack Sizes: 50mg, 250mg. US Biological Life Sciences.
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Diethyl suberate
Diethyl suberate. Group: Biochemicals. Alternative Names: Subericacid diethyl ester; Octanedioic acid diethyl ester. Grades: Highly Purified. CAS No. 2050-23-9. Pack Sizes: 100g, 250g, 500g, 1kg. US Biological Life Sciences.
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Disuccinimidyl suberate
Disuccinimidyl suberate. Group: Biochemicals. Alternative Names: DSS; Disuccinimidyl octanedioate; Subericacid bis(N-hydroxysuccinimide ester). Grades: Highly Purified. CAS No. 68528-80-3. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences.
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DSS Crosslinker
DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: Disuccinimidyl suberate; bis(2,5-dioxopyrrolidin-1-yl) octanedioate; Subericacid bis(N-hydroxysuccinimide ester). Grades: >98.0%. CAS No. 68528-80-3. Molecular formula: C16H20N2O8. Mole weight: 368.34.
Monomethyl Suberate
Monomethyl Suberate was used in the synthetic preparation of Prostaglandin E1 (P838600), a primary prostaglandin and a peripheral vasodilator. Group: Biochemicals. Alternative Names: Octanedioic Acid, Monomethyl Ester; SubericAcid Methyl Ester; SubericAcid, Monomethyl Ester; 8-Methoxy-8-oxooctanoic Acid; Methyl 1,8-Octanedionate; Methyl 7-Carboxyheptanoate. Grades: Highly Purified. CAS No. 3946-32-5. Pack Sizes: 5g. US Biological Life Sciences.
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Suberoyl Chloride
Suberoyl Chloride. Uses: This product is suitable for scientific research. Group: Monomers. Alternative Names: Octanedioic acid dichloride, Subericacid dichloride. CAS No. 10027-07-3. Product ID: octanedioyl dichloride. Molecular formula: 211.09. Mole weight: ClCO(CH2)6COCl. ClC(=O)CCCCCCC(Cl)=O. 1S/C8H12Cl2O2/c9-7 (11)5-3-1-2-4-6-8 (10)12/h1-6H2. PUIBKAHUQOOLSW-UHFFFAOYSA-N.
Suberoyl Chloride
This product is suitable for scientific research. Group: Polymer/macromoleculedicarboxylic acid chloride monomers. Alternative Names: SubericAcid Dichloride; Octanedioic Acid Dichloride. CAS No. 10027-07-3. Molecular formula: C8H12Cl2O2. Mole weight: 211.08 g/mol. Appearance: Colorless to Light Orange to Yellow Clear Liquid. Purity: 98.0%(GC)(T). IUPACName: octanedioyl dichloride. Canonical SMILES: ClC(=O)CCCCCCC(Cl)=O. Density: 1.172 g/mL at 25 °C (lit.). Catalog: ACM-MO-10027073.
3-Pyrrolidinesulfonic acid,1,1'-[(1,8-dioxo-1,8-octanediyl)bis(oxy)]-bis[2,5-dioxo-,disodium salt
A SAHA derivative with antiproliferative activity in several human cancer cell lines. Group: Biochemicals. Alternative Names: N1-Hydroxy-N8- (4-iodophenyl) octanediamide; 4-Iodo-SAHA. Grades: Highly Purified. CAS No. 1219807-87-0. Pack Sizes: 100mg. US Biological Life Sciences.
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Coumarin suberoylanilide hydroxamic acid
Coumarin suberoylanilide hydroxamic acid. Group: Biochemicals. Alternative Names: N1-Hydroxy-N8-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)octanediamide; Coumarin-SAHA. Grades: Highly Purified. CAS No. 1260635-77-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C18H22N2O5. US Biological Life Sciences.
An intermediate in the production of Suberoylanilide Hydroxamic Acid. Group: Biochemicals. Alternative Names: N1,N8-Diphenyloctanediamide. Grades: Highly Purified. CAS No. 14354-86-0. Pack Sizes: 250mg. US Biological Life Sciences.
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N-SuberyLglycine (2,2-D2)
Isotope-labeled Amino Acids2H Labeled Compounds. Alternative Names: N-Suberylglycine-2,2-D2. CAS No. 1219799-02-6. Molecular formula: C10H15D2NO5. Mole weight: 233.26. Appearance: White powder. Catalog: ACM1219799026.
Ramage Linker
Ramage Linker, also known as Ramage-Linker can be used for preparation of peptide amides specially as an acid-labile peptide amide linker. Synonyms: Fmoc-suberol; 2-[[5-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-2-yl]oxy]acetic Acid; (R,S)-2-[[5-(9-FLUORENYLMETHYLOXYCARBONYLAMINO)-DIBENZO[A,D]CYCLOHEPTANE-2-YL]OXY]-ACETIC ACID; 5-FMoc-aMino-2-carboxyMethoxy-10,11-dihydro-5H-dibenzo[a,d]cycloheptene; Fmoc-Suberol; 5-FMOC-AMINO-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTENE-2-HYDROXY ACETIC ACID; REF DUPL: Ramage Linker,Fmoc-Suberol. Grades: 98% (HPLC). CAS No. 212783-75-0. Molecular formula: C32H27NO5. Mole weight: 505.56.
Sodium Methanethiolate 95+%
Sodium methanethiolate is used as a nucleophile in organic synthesis. Sodium methanethiolate is also being used as a reagent to synthesize thiol-based suberoylanilide hydroxamic acid (SAHA) analogues, compounds that act as potent histone deacetylase inhibitors. Group: Biochemicals. Alternative Names: Methanethiol Sodium Salt (1:1); (Methylthio)sodium; Methyl Mercaptan Sodium Salt; Methylthiosodium; Sodium Methanesulfenate; Sodium Methanethiolate; Sodium Methyl Mercaptan; Sodium Methyl Sulfide; Sodium Methylmercaptide; Sodium Methylthiolate; Sodium Thiomethoxide; Sodium Thiomethylate. Grades: Highly Purified. CAS No. 5188-7-8. Pack Sizes: 2.5g, 10g. Molecular Formula: CH?NaS, Molecular Weight: 70.09. US Biological Life Sciences.
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Suberanilic Acid
An intermediate in the production of Suberoylanilide Hydroxamic Acid and other histone deacetylase inhibitors. Group: Biochemicals. Alternative Names: 8-Oxo-8-(phenylamino)octanoic Acid. Grades: Highly Purified. CAS No. 149648-52-2. Pack Sizes: 200mg. US Biological Life Sciences.
Worldwide
Suberanilic Acid-d5
An intermediate in the production of labeled uberoylanilide Hydroxamic Acid and other labeled histone deacetylase inhibitors. Group: Biochemicals. Alternative Names: 8-Oxo-8-(phenylamino)octanoic Acid-d5. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Suberohydroxamic acid
SBHA is a histone deacetylase (HDAC) inhibitor (ID50 = 0.25 and 0.3 μM for HDAC1 and HDAC3, respectively). SBHA can be used in combination with cytostatic drugs to enhance their effects against cancer cells. Synonyms: N,N'-dihydroxyoctanediamide. CAS No. 38937-66-5. Molecular formula: C8H16N2O4. Mole weight: 204.22.
A potent, selective, cell permeable histone deacetylase inhibitor (HDAC). Displays anti-angiogenic activity by interfering with VEGF signaling in human umbilical vein endothelial cells (HUVECs). Induces differentiation in uman breast cancer cells. Group: Biochemicals. Alternative Names: SAHA-d5; N-Hydroxy-N-phenyl-d5-octanediamide;Zolinza-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Suberoylanilide hydroxamic acid b-D-glucuronide
Suberoylanilide hydroxamic acid b-D-glucuronide is a highly efficacious inhibitor, aiding in studying cancer, with a distinct focus on histone deacetylases (HDACs). Synonyms: 1-O-[[1,8-Dioxo-8-(phenylamino)octyl]amino]-b-D-Glucopyranuronic acid. CAS No. 863456-50-2. Molecular formula: C20H28N2O9. Mole weight: 440.44.
A potent, selective, cell permeable histone deacetylase inhibitor (HDAC). Displays anti-angiogenic activity by interfering with VEGF signaling in human umbilical vein endothelial cells (HUVECs). Induces differentiation in uman breast cancer cells. Group: Biochemicals. Alternative Names: SAHA; N-Hydroxy-N-phenyloctanediamide; N-Hydroxy-N-phenyloctanediamide; Zolinza; Suberoylanilide-hydroxamic acid, Vorinostat. Grades: Highly Purified. CAS No. 149647-78-9. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Suberoyl Bis-hydroxamic Acid
Histone deacetylase inhibitor. A cell-permeable inhibitor of HDAC1 and HDAC3. Shown to suppresses the growth of proliferating keratinocytes and squamous cell carcinoma cells. Group: Biochemicals. Alternative Names: N1, N8-Dihydroxyoctane diamide. Grades: Highly Purified. CAS No. 38937-66-5. Pack Sizes: 2.5g. US Biological Life Sciences.
Worldwide
Suberylglycine
Suberylglycine is an acyl glycine, which is a normally minor metabolite of fatty acid. Uses: Scientific research. Group: Natural products. CAS No. 60317-54-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-113367.
Vorinostat
Vorinostat (rINN) also known as suberanilohydroxamic acid (suberoyl+anilide+hydroxamic acid abbreviated as SAHA) is a member of a larger class of compounds that inhibit histone deacetylases (HDAC). Histone deacetylase inhibitors (HDI) have a broad spectrum of epigenetic activities.Vorinostat is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL) when the disease persists, gets worse, or comes back during or after treatment with other medicines. The compound was developed by Columbia University chemist Ronald Breslow and Memorial Sloan-Kettering researcher Paul Marks. Group: Inhibitors. Alternative Names: Suberoylanilidehydroxamic Acid; N-Hydroxy-N-phenyloctanediamide; Vorinostat/SAHA; Suberoylanilide Hydroxamic Acid. CAS No. 149647-78-9. Molecular formula: C14H20N2O3. Mole weight: 264.32. Appearance: White crystalline solid. Purity: 0.9962. Density: 1.174 g/cm³. Catalog: ACM149647789.
Vorinostat
Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1 , HDAC2 and HDAC3 (Class I) , HDAC6 and HDAC7 (Class II) and HDAC11 (Class IV) , with ID 50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis [1] [4]. Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAHA; Suberoylanilide hydroxamic acid. CAS No. 149647-78-9. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-10221.
Vorinostat
Vorinostat (suberoylanilide hydroxamic acid, SAHA) is an HDAC inhibitor with IC50 of ~10 nM. Uses: Antineoplastic agents; histone deacetylase inhibitors. Synonyms: MK-0683, MK 0683, MK0683, SAHA, M344, CCRIS 8456, HSDB 7930, Vorinostat, suberoylanilide hydroxamic acid, Zolinza. Grades: >98%. CAS No. 149647-78-9. Molecular formula: C14H20N2O3. Mole weight: 264.3.
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