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Sumatriptan (GR 43175) is an orally active 5-HT1 receptor agonist with IC 50 s of 7.3 nm, 9.3nm and 17.8 nm for 5-HT 1D , 5-HT 1B and 5-HT 1F receptors, respectively. Sumatriptan can be used for migraine headache research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR 43175 free base. CAS No. 103628-46-2. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B0121B.
Sumatriptan
Sumatriptan is a Serotonin-1b and Serotonin-1d Receptor Agonist that acts selectively at 5HT1 receptors. It is a sulfonamide triptan with vasoconstrictor activity. It selectively binds to and activates serotonin 5-HT1D receptors in the central nervous system, thus constricts cerebral blood vessels. It may also relieve vascular headaches by decreasing the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater. It is a medication used for the treatment of migraine headaches. Uses: Sumatriptan is a medication used for the treatment of migraine headaches. Synonyms: Imitrex; Sumatran; Sumax; Sumatriptanum; 1-[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]-N-methylmethanesulfonamide; (3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide; GR-43175; GR43175. Grades: 95%. CAS No. 103628-46-2. Molecular formula: C14H21N3O2S. Mole weight: 295.40.
A serotonin 5HT1-receptor agonist. Antimigraine. Group: Biochemicals. Alternative Names: 3-[2-(Dimethyl-d6-amino)-ethyl]-N-methyl-1H-indole-5-methanesulfonamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Sumatriptan-d6 succinate
Sumatriptan-d6 succinate is the deuterium labeled Sumatriptan succinate. Sumatriptan succinate is an orally active 5-HT1 receptor agonist with K i s of 17 nM, 27 nM and 100 nM for 5-HT1D , 5-HT1B and 5-HT1A receptors , respectively. Sumatriptan succinate can be used for migraine headache research [1] [2] [3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: GR 43175C-d6. CAS No. 1215621-31-0. Pack Sizes: 1 mg. Product ID: HY-B0121BS.
Sumatriptan-d6 succinate
Sumatriptan-d6 succinate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-[2-(Dimethyl-d6-amino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide, Succinate, Imigran, Imitrex. Product Category: Heterocyclic Organic Compound. CAS No. 1215621-31-0. Molecular formula: C18H21D6N3O6S. Mole weight: 419.53. Purity: 0.96. IUPACName: 1-[3-[2-[bis(trideuteriomethyl)amino]ethyl]-1H-indol-5-yl]-N-methylmethanesulfonamide;butanedioic acid. Canonical SMILES: CNS(=O)(=O)CC1=CC2=C(C=C1)NC=C2CCN(C)C.C(CC(=O)O)C(=O)O. Product ID: ACM1215621310. Alfa Chemistry ISO 9001:2015 Certified.
Labelled Sumatriptan, a serotonin 5HT1-receptor agonist. Group: Biochemicals. Alternative Names: 3-[2-(Dimethyl-d6-amino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide, Succinate, Imigran, Imitrex. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Sumatriptan Dimer Impurity-d4
Sumatriptan Dimer Impurity-d4. Group: Biochemicals. Alternative Names: 1-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-3-[2-(Dimethylamino)ethyl]-N-methyl-indole-5-methanesulfonamide-d4. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C27H33D4N5O2S, Molecular Weight: 499.7. US Biological Life Sciences.
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Sumatriptan EP Impurity A
Sumatriptan EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 545338-89-4. Molecular Formula: C27H37N5O2S. Mole Weight: 495.69. Catalog: APB545338894.
Sumatriptan EP impurity B
One of the impurities of Sumatriptan that is a 5-HT receptro agonist. Synonyms: Monodesmethyl sumatriptan; N-Desmethyl SumatriptanDiscontinued; 88919-51-1; Sumatriptan EP Impurity B; Sumatriptan succinate specified impurity B [EP]. Grades: > 95%. CAS No. 88919-51-1. Molecular formula: C13H19N3O2S. Mole weight: 281.38.
Sumatriptan EP Impurity B
Sumatriptan EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 88919-51-1. Molecular Formula: C13H19N3O2S. Mole Weight: 281.37. Catalog: APB88919511.
Sumatriptan EP impurity C
One of the impurities of Sumatriptan that is a 5-HT receptro agonist. Synonyms: Sumatriptan EP Impurity C; Sumatriptan USP Related Compound C; [3-[2-(Dimethylamino)ethyl]-1-(hydroxymethyl)-1H-indol-5-yl]- N-methylmethanesulphonamide. Grades: > 95%. Molecular formula: C15H23N3O3S. Mole weight: 325.43.
Sumatriptan EP Impurity C
Sumatriptan EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1797905-62-4. Molecular Formula: C15H23N3O3S. Mole Weight: 325.43. Catalog: APB1797905624.
Sumatriptan EP Impurity D
Sumatriptan EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 212069-94-8. Molecular Formula: C14H21N3O3S. Mole Weight: 311.4. Catalog: APB212069948.
Sumatriptan EP impurity E
One of the impurities of Sumatriptan that is a 5-HT receptro agonist. Synonyms: 3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide; 1-(3-(2-Aminoethyl)-1H-indol-5-yl)-N-methylmethanesulfonamide; Didesmethyl sumatriptan; 1-[3-(2-aminoethyl)-1H-indol-5-yl]-N-methylmethanesulfonamide. Grades: > 95%. CAS No. 88919-22-6. Molecular formula: C12H17N3O2S. Mole weight: 267.35.
Sumatriptan EP Impurity E
Sumatriptan EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 88919-22-6. Molecular Formula: C12H17N3O2S. Mole Weight: 267.35. Catalog: APB88919226.
Sumatriptan EP Impurity F
Sumatriptan EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2074615-63-5. Molecular Formula: C13H17N3O2S. Mole Weight: 279.36. Catalog: APB2074615635.
Sumatriptan EP Impurity H
Sumatriptan EP Impurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1391052-59-7. Molecular Formula: C27H37N5O2S. Mole Weight: 495.69. Catalog: APB1391052597.
Sumatriptan Hydroxy-Oxindole Impurity (Sumatriptan Impurity 1). Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 5MG. Catalog: APS013024. Format: Neat. Shipping: Room Temperature.
Sumatriptan Impurity 1
One of the impurities of Sumatriptan that is a 5-HT receptro agonist. Synonyms: Sumatriptan Impurity 1; Sumatriptan Hydroxy-Oxindole Impurity; 1-(3-(2-(Dimethylamino)ethyl)-3-hydroxy-2-oxoindolin-5-yl)-N-methylmethane. Grades: > 95%. Molecular formula: C14H21N3O4S. Mole weight: 327.41.
Sumatriptan Impurity 2
One of the impurities of Sumatriptan that is a 5-HT receptro agonist. Synonyms: Sumatriptan Impurity 2. Grades: > 95%. Molecular formula: C14H22N3O3S. Cl. Mole weight: 347.86.
Sumatriptan Impurity 2
Sumatriptan Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2250254-19-2. Molecular Formula: C14H21N3O4S. Mole Weight: 327.4. Catalog: APB2250254192.
Sumatriptan Impurity 3
One of the impurities of Sumatriptan that is a 5-HT receptro agonist. Synonyms: Sumatriptan Impurity 3; 1-(3-(2-(Dimethylamino)ethyl)-1-((5-((N-methylsulfamoyl)methyl)-1H-indol-3-yl)methyl)-1H-indol-5-yl)-N-methylmethanesulfonamide. Grades: > 95%. Molecular formula: C25H33N5O4S2. Mole weight: 531.70.
Sumatriptan Impurity 3
Sumatriptan Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 4025-75-6. Molecular Formula: C7H6ClNO4S. Mole Weight: 235.64. Catalog: APB4025756.
Sumatriptan Impurity A
One of the impurities of Sumatriptan that is a 5-HT receptro agonist. Synonyms: Sumatriptan succinate specified impurity A [EP]; Sumatriptan succinate related compound A free base; (3-(2-(Dimethylamino)ethyl)-2-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)methyl)-1H-indol-5-yl)-N-methylmethanesulfonamide. Grades: > 95%. CAS No. 545338-89-4. Molecular formula: C27H37N5O2S. Mole weight: 495.69.
Sumatriptan Impurity F
One of the impurities of Sumatriptan that is a 5-HT receptro agonist. Synonyms: Sumatriptan Impurity F; N-Methyl-1-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-6-yl)methanesulfonamide Succinate. Grades: > 95%. Molecular formula: C13H17N3O2S. Mole weight: 279.36.
Sumatriptan Impurity G
One of the impurities of Sumatriptan that is a 5-HT receptro agonist. Synonyms: Sumatriptan Impurity G; N-Methyl-1-(2-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-6-yl)methanesulfonamide. Grades: > 95%. Molecular formula: C14H19N3O2S. Mole weight: 293.39.
Sumatriptan Impurity H
One of the impurities of Sumatriptan that is a 5-HT receptro agonist. Synonyms: Sumatriptan Related Compound H; Sumatriptan Dimer Impurity; Sumatriptan EP Impurity H; N-(3-(2-(dimethylamino)ethyl)-1-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)methyl)-1H-indol-5-yl)-N-methylmethanesulfonamide. Grades: > 95%. CAS No. 1391052-59-7. Molecular formula: C27H37N5O2S. Mole weight: 495.69.
Sumatriptan N-oxide
Sumatriptan N-oxide. Group: Biochemicals. Alternative Names: 3-[2- (Dimethyloxidoamino) ethyl]-N-methyl-1H-indole-5-methanesulfonamide; GR 112504. Grades: Highly Purified. CAS No. 212069-94-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C14H21N3O3S. US Biological Life Sciences.
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Sumatriptan N-Oxide
Sumatriptan N-Oxide. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Ph Eur Sumatriptan Impurity Mixture, BP Sumatriptan Impurity D, Sumatriptan Test Mix for Impurity Identification Solution 2, GR 112504, Ph Eur Sumatriptan Impurity D, GR 112504X, Sumatriptan N-Oxide,3-[2-(Dimethyloxidoamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide, Sumatriptan N-oxide (GR 112504X). CAS No. 212069-94-8. Pack Sizes: 10MG. IUPAC Name: N,N-dimethyl-2-[5-(methylsulfamoylmethyl)-1H-indol-3-yl]ethanamine oxide. Molecular Formula: C14H21N3O3S. Mole Weight: 311.40. Catalog: APS212069948. SMILES: CNS (=O) (=O)Cc1ccc2[nH]cc (CC[N+] (C) (C)[O-])c2c1. Format: Neat. Shipping: Room Temperature.
Sumatriptan succinate
Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with IC 50 s of 7.3 nm, 9.3nm and 17.8 nm for 5-HT 1D , 5-HT 1B and 5-HT 1F receptors, respectively. Sumatriptan succinate can be used for migraine headache research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR 43175 succinate. CAS No. 103628-48-4. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0121.
Sumatriptan succinate
Sumatriptan succinate. Group: Biochemicals. Grades: Purified. CAS No. 103628-48-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Sumatriptan succinate
Sumatriptan Succinate is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches. Uses: Vasoconstrictor agents. Synonyms: GR 43175; GR43175; GR-4317. Grades: >98%. CAS No. 103628-48-4. Molecular formula: C14H21N3O2S.C4H6O4. Mole weight: 413.49.
A serotonin 5HT1-receptor agonist. Group: Biochemicals. Alternative Names: 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide, Succinate, Imigran, Imitrex. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
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Sumatriptan Succinate EP impurity D
One metabolite impurities of Sumatriptan that is a 5-HT receptro agonist. Synonyms: Sumatriptan N-Oxide; Sumatriptan Succinate EP Impurity D; N,N-dimethyl-2-[5-(methylsulfamoylmethyl)-1H-indol-3-yl]ethanamine oxide. Grades: > 95%. CAS No. 212069-94-8. Molecular formula: C14H21N3O3S. Mole weight: 311.41.
An antimigraine agent. A Sumatriptan intermediate. Group: Biochemicals. Alternative Names: Didesmethyl Sumatriptan. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences.
Degradation product of Sumatriptan Succinate. Group: Biochemicals. Alternative Names: 3-[2-(Dimethylamino)ethyl]-1H-Indole-5-methanol. Grades: Highly Purified. CAS No. 334981-08-7. Pack Sizes: 10mg. US Biological Life Sciences.
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5-Nonyloxytryptamine oxalate
5-Nonyloxytryptamine oxalate is a potent agonist of the serotonin (5-HT) receptor 5-HT1Dβ with an EC50 value of 68 nM for adenylate cyclase activity in CHOKM6 cells transfected with the human 5-HT1Dβ receptor. It is several times more potent than sumatriptan and inactive as a 5-HT1A agonist (Ki at 5-HT1B = 1 nM, selectivity over 5-HT1A > 300-fold). Synonyms: 5-(Nonyloxy)-1H-Indole-3-ethanamine ethanedioate; 5-(Nonyloxy)tryptamine oxalate; 5-Nonyloxytryptamine oxalate. Grades: ≥99% by HPLC. CAS No. 157798-13-5. Molecular formula: C19H30N2O.C2H2O4. Mole weight: 392.49.
Used in the preparation of Sumatriptan impurity. Group: Biochemicals. Alternative Names: 3-[2-(Dimethylamino)-2-oxoacetyl]-1H-indole-5-carboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 1052181-84-6. Pack Sizes: 25mg. US Biological Life Sciences.
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GR 49336
A metabolite of Sumatriptan. Group: Biochemicals. Alternative Names: 5-[[ (Methylamino) sulfonyl]methyl]-. Grades: Highly Purified. CAS No. 103628-44-0. Pack Sizes: 2.5mg. US Biological Life Sciences.
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