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A multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK). Antineoplastic. Group: Biochemicals. Alternative Names: N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide Malate; Sutent; SU-11248. Grades: Highly Purified. CAS No. 341031-54-7. Pack Sizes: 10mg. US Biological Life Sciences.
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Sunitinib Malate
Sunitinib Malate (SU 11248 Malate) is a multi-targeted receptor tyrosine kinase inhibitor with IC 50 s of 80 nM and 2 nM for VEGFR2 and PDGFRβ , respectively [1]. Sunitinib Malate, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SU 11248 Malate. CAS No. 341031-54-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-10255.
A multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK). Sunitinib and its active metabolite (SU012662) are selective inhibitors of multiple receptor tyrosine kinases, including platelet-derived growth factor receptor and vascular endothelial growth factor receptor, that are associated with tumor growth and angiogenesis. Group: Biochemicals. Alternative Names: Sutent. Grades: Highly Purified. CAS No. 341031-54-7. Pack Sizes: 100mg, 250mg, 500mg. US Biological Life Sciences.
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Angiogenesis related Compound Library
A unique collection of 1370 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS); - Targets include angiogenesis signaling, and related targets such as S1P, VEGFR, PDGF, etc. ; - Includes approved drugs targeting angiogenesis, such as Sunitinib Malate, Lenalidomide, sorafenib, Erlotinib; drugs in clinical development with the most potential targeting angiogenesis, such as Vatalanib, Orantinib, 2-Methoxyestradiol (Panzem), Celecoxib; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4800. Categories: Angiogenesis related Compounds Libraries.
Sunitinib (as the malate salt) is the active ingredient in the drug sold under the trade name Sutent. This drug is a small molecule receptor tyrosine kinase inhibitor that has been approved in at least one country for the treatment of patients having gastrointestinal stromal tumors or renal cell carcinomas. Group: Biochemicals. Alternative Names: N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide; SU-11248; Sutent; PHA-290940AD; PNU-290940AD. Grades: Highly Purified. CAS No. 557795-19-4. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C22H27FN4O2, Molecular Weight: 398.47. US Biological Life Sciences.
Worldwide
Sunitinib
Sunitinib (as the malate salt) is the active ingredient in the drug sold under the trade name Sutent. This drug is a small molecule receptor tyrosine kinase inhibitor that has been approved in at least one country for the treatment of patients having gastrointestinal stromal tumors or renal cell carcinomas. Group: Biochemicals. Alternative Names: N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide; SU-11248; Sutent; PHA-290940AD; PNU-290940AD. Grades: Highly Purified. CAS No. 557795-19-4. Pack Sizes: 10mg, 100mg. Molecular Formula: C22H27FN4O2, Molecular Weight: 398.47. US Biological Life Sciences.
Worldwide
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