Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Tariquidar, also known as XR9576, is a P-glycoprotein inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non-competitively binds to the p-glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. Inhibition of transmembrane transport may result in increased intracellular concentrations of an anticancer drug, thereby augmenting its cytotoxicity. Synonyms: XR 9576; XR9576; XR-9576; D06008. Grades: >98%. CAS No. 206873-63-4. Molecular formula: C38H38N4O6. Mole weight: 646.744.
Tariquidar. Uses: Designed for use in research and industrial production. CAS No. 206873-63-4. Molecular formula: C38H38N4O6. Mole weight: 646.73. Purity: 0.98. Product ID: ACM206873634. Alfa Chemistry ISO 9001:2015 Certified.
Tariquidar dihydrochloride is a potent P-glycoprotein (P-gp) inhibitor (IC50 = 5.1 nM). Tariquidar was found to reverse drug resistance in multiple MDR cell lines. Tariquidar binds to the p-glycoprotein transporter, and inhibits transmembrane transport of anticancer drugs, leading to increased concentrations and enhanced cytotoxic effects of anticancer drugs. Synonyms: N-[2-[[[4-[2- (3, 4-dihydro-6, 7-dimethoxy-2 (1H) -isoquinolinyl) ethyl]phenyl]amino]carbonyl]-4, 5-dimethoxyphenyl]-3-quinolinecarbxamide dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1992047-62-7. Molecular formula: C38H38N4O6.2HCl. Mole weight: 719.66.
Tariquidar methanesulfonate hydrate
Tariquidar methanesulfonate is a potent and selective noncompetitive inhibitor of P-glycoprotein(Kd =5.1 nM). Uses: P-glycoprotein inhibitor, potent and selective. Synonyms: XR 9576; XR9576; XR-9576;N-[2-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-4,5-dimethoxyphenyl]quinoline-3-carboxamide;methanesulfonic acid;trihydrate. Grades: ≥98%. CAS No. 625375-83-9. Molecular formula: C40H52N4O15S2. Mole weight: 892.99.
2-Amino-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4,5-dimethoxybenzamide is an intermediate in the synthesis of Tariquidar (T007600), a P-glycoprotein drug efflux pump inhibitor that is potentially used in cancer patients. Group: Biochemicals. Grades: Highly Purified. CAS No. 849668-91-3. Pack Sizes: 25mg, 100mg. Molecular Formula: C28H33N3O5. US Biological Life Sciences.
Worldwide
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.