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| Product | Description | |
|---|---|---|
| Teniposide | Teniposide is a chemotherapeutic medication mainly used in the treatment of childhood acute lymphocytic leukemia (ALL).It is in a class of drugs known as podophyllotoxin derivatives and slows the growth of cancer cells in the body. Uses: Antineoplastic agents; enzyme inhibitors; nucleic acid synthesis inhibitors. Synonyms: NSC-122819; NSC 122819; NSC122819; VM26; VM-26; VM 26; HSDB 6546; HSDB6546; HSDB-6546; CCRIS 2058. Brand name: Vumon; Vehem. Abbreviations: EPT; PTG. Grades: >98%. CAS No. 29767-20-2. Molecular formula: C32H32O13S. Mole weight: 656.65. |  |
| Teniposide | Teniposide is a podophyllotoxin derivative, acts as a topoisomerase II inhibitor, and used as a chemotherapeutic agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VM26. CAS No. 29767-20-2. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13761. |  |
| 2'',3''-Bis-O-(Dichloroacetyl) Etoposide | 2'',3''-Bis-O-(Dichloroacetyl) Etoposide is an impurity of Etoposide (E933750). Etoposide is a DNA topoisomerase II inhibitor. Etoposide is semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide and it is an Antineoplastic. Group: Biochemicals. Grades: Highly Purified. CAS No. 260974-95-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C33H32Cl4O15, Molecular Weight: 810.41. US Biological Life Sciences. |  Worldwide |
| 2'',3''-Bis-O-(Dichloroacetyl) Etoposide | 2'',3''-Bis-O-(Dichloroacetyl) Etoposide is an impurity of Etoposide. Etoposide is a DNA topoisomerase II inhibitor. Etoposide is a semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide and it is an antineoplastic. Synonyms: 9-[[2,3-Bis-O-(2,2-dichloroacetyl)-4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one 6-Acetate; (5R,5aR,8aR,9S)-9-[[2,3-Bis-O-(dichloroacetyl)-4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one. CAS No. 260974-95-6. Molecular formula: C33H32Cl4O15. Mole weight: 810.41. | |
| 4'-(O-Podophyllotoxin-9-oxy) Etoposide | 4'-(O-Podophyllotoxin-9-oxy) Etoposide is an impurity of Etoposide. Etoposide is a DNA topoisomerase II inhibitor, as well as semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide and it is an antineoplastic. Molecular formula: C50H50O20. Mole weight: 970.92. | |
| Aclarubicin A | Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. It intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. It is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. It has potent antineoplastic activity. It is used in the treatment of cancer. It can induce histone eviction from chromatin upon intercalation. It has been listed. Uses: Aclarubicin has potent antineoplastic activity. it is used in the treatment of cancer. it can induce histone eviction from chromatin upon intercalation. Synonyms: 11-Dioxo-4-((2,3,6-trideoxy-4-o-(2,6-dideoxy-4-o-((2r-trans)-tetrahydro-6-met;1-naphthacenecarboxylicacid,2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6;(1R,2R,4S)-methyl 4-(((2R,5S,6S)-4-(dimethylamino)-5-(((2S,4S,5S,6S)-4-hydroxy-6-methyl-5-(((2R,6S). Grades: ≥95%. CAS No. 57576-44-0. Molecular formula: C42H53NO15. Mole weight: 811.88. | |
| Aclarubicin hydrochloride | Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. Aclarubicin intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting replication and repair of DNA and RNA, and protein synthesis. Aclarubicin is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. This agent is less cardiotoxic than doxorubicin and daunorubicin. Uses: Antibiotics, antineoplastic. Synonyms: Aclacinon; Aclaplastin; Aclacinomycin A Hydrochloride; Aclarubicin HCl; Aclarubicina Clorhidrato [Spanish]. Grades: >98%. CAS No. 75443-99-1. Molecular formula: C42H54ClNO15. Mole weight: 848.33. | |
| Bmi1-Ring1A E3 Ligase Inhibitor, PRT4165 (2-(Pyridin-3-ylmethylene)-1H-indene-1,3(2H)-dione) | A cell-permeable indandione compound that inhibits the Bmi1-Ring1A E3 complex ubiquitin ligase activity both in cell-free assays (by 100% against self- and Top2alpha ubiquitination at 25 and 50uM, respectively) and in HeLa cells (by 100% against Bmi1 ubiquitination at 50uM). Shown to greatly potentiate Teniposide (VM26) cancer cytotoxicity (by 10-fold in A375 and A549 cultures at 5.5 and 33uM, respectively) by preventing Top2alpha degradation following VM26 treatment (100% inhibition at 50uM in HeLa cells). Group: Biochemicals. Grades: Highly Purified. CAS No. 31083-55-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Etoposide-d3 | A labeled DNA topoisomerase II inhibitor. Semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide. Antineoplastic. Group: Biochemicals. Alternative Names: (5R,5aR,8aR,9S)-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
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