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Terpendole E is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Albophoma yamenashiensis. The IC50 that inhibits ACAT in macrophages is 0.29 μmol/L, and the CD50 that causes 50% cell damage is greater than 23.4 μmol/L. Synonyms: (2S, 4R, 4aR, 4bR, 6aS, 12bS, 12cS, 14aS)-2-(2-Hydroxypropan-2-yl)-4a, 12b, 12c-trimethyl-3, 4, 4a, 4b, 5, 6, 6a, 7, 12, 12b, 12c, 13, 14, 14a-tetradecahydro-2H-chromeno[5', 6':6, 7]indeno[1, 2-b]indol-4-ol. Grades: >98%. CAS No. 167427-23-8. Molecular formula: C28H39NO3. Mole weight: 437.61.
Terpendole E (1'alpha-Hydroxy-Paspaline)
Inhibitor to Acyl-CoA: Cholesterol acyltransferase (ACAT), Mitotic kinesin Eg5 (Mitotic Kinesin Spindle Protein; KSP) and Specific M phase. Group: Biochemicals. Alternative Names: 1'alpha-Hydroxy-Paspaline. Grades: Highly Purified. CAS No. 167427-23-8. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
Terpendole C
Inhibitor for Acyl-CoA, cholesterol acyltransferase (ACAT) isozymes ACAT1 and ACAT2, Tremorgenic and Cholesteryl ester (CE) synthesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 156967-65-6. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
Terpendole C
Isolated from Albophoma yamanashiensis. An acyl-CoA:cholesterol acyltransferase (ACAT) isozymes ACAT1 and ACAT2 inhibitor. Also acts as a tremorgen and cholesteryl ester (CE) synthesis inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 156967-65-6. Pack Sizes: 250ug, 1mg. US Biological Life Sciences.
Worldwide
Terpendole C
Terpendole C is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Albophoma yamenashiensis. The IC50 that inhibits ACAT in macrophages is 0.46 μmol/L, and the CD50 that causes 50% cell damage is greater than 24.1 μmol/L. Synonyms: (3S, 4aR, 4bR, 5aS, 5bS, 7aS, 13bS, 13cR, 15aS, 16aS)-1, 1, 13b, 13c-tetramethyl-3-(2-methylprop-1-en-1-yl)-1, 4a, 4b, 6, 7, 7a, 8, 13, 13b, 13c, 14, 15, 15a, 16a-tetradecahydro-5bH-[1, 3]dioxino[5'', 4'':2', 3']oxireno[2'', 3'':4', 4a']chromeno[5', 6':6, 7]indeno[1, 2-b]indol-5b-ol; (-)-terpendole C. Grades: >98%. CAS No. 156967-65-6. Molecular formula: C32H41NO5. Mole weight: 519.67.
Terpendole L
Terpendole F is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Albophoma yamenashiensis. The IC50 that inhibits ACAT in macrophages is 0.29 μmol/L, and the CD50 that causes 50% cell damage is greater than 23.4 μmol/L. Synonyms: (3S, 4aR, 4bR, 5aS, 5bS, 7aS, 13bS, 13cR, 15aS, 16aS)-1, 1, 13b, 13c-tetramethyl-9-(3-methylbut-2-en-1-yl)-3-(2-methylprop-1-en-1-yl)-1, 4a, 4b, 6, 7, 7a, 8, 13, 13b, 13c, 14, 15, 15a, 16a-tetradecahydro-5bH-[1, 3]dioxino[5'', 4'':2', 3']oxireno[4', 4a']chromeno[5', 6':6, 7]indeno[1, 2-b]indol-5b-ol. Molecular formula: C37H49NO5. Mole weight: 587.79.
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