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| Product | Description | |
|---|---|---|
| Tetrabenazine Related Impurity 1 | One impurity of Tetrabenazine, which is a VMAT-2 inhibitor and has been found to be effective in the treatment of hyperkinetic movement disorder at some extent. Synonyms: 1,3,4,6,7,11b-Hexahydro-1-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one; 1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-1-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one. Grades: > 95%. CAS No. 99672-64-7. Molecular formula: C19H27NO3. Mole weight: 317.43. |  |
| Tetrabenazine Related Impurity 18 (2R,3S,11bS, D-Val) | Tetrabenazine Related Impurity 18 (2R,3S,11bS, D-Val) is one of Tetrabenazine impurities. Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder. It is a monoamine-depleting and a dopamine-receptor-blocking drug and is an effective and safe drug for the treatment of a variety of hyperkinetic movement disorders. Molecular formula: C24H38N2O4. Mole weight: 418.57. | |
| Tetrabenazine Related Impurity 2 | One impurity of Tetrabenazine, which is a VMAT-2 inhibitor and has been found to be effective in the treatment of hyperkinetic movement disorder at some extent. Synonyms: (3S,11bR)-3-isobutyl-9,10-dimethoxy-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one. Grades: > 95%. CAS No. 1381929-92-5. Molecular formula: C19H27NO3. Mole weight: 317.43. | |
| Tetrabenazine Related Impurity 29 | Tetrabenazine Related Impurity 29 (Tetradehydrotetrabenazine) is one of Tetrabenazine impurities. Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder. It is a monoamine-depleting and a dopamine-receptor-blocking drug and is an effective and safe drug for the treatment of a variety of hyperkinetic movement disorders. Synonyms: Tetradehydrotetrabenazine. Molecular formula: C19H23NO3. Mole weight: 313.39. | |
| Tetrabenazine Related Impurity 3 | One impurity of Tetrabenazine, which is a VMAT-2 inhibitor and has been found to be effective in the treatment of hyperkinetic movement disorder at some extent. Synonyms: 3-Des(2-methylpropyl)-3-n-Butyl Tetrabenazine; 3-Butyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one. Grades: > 95%. CAS No. 19328-35-9. Molecular formula: C19H27NO3. Mole weight: 317.43. | |
| Tetrabenazine Related Impurity 4 | Tetrabenazine Related Impurity 4 is one of Tetrabenazine impurities. Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder. It is a monoamine-depleting and a dopamine-receptor-blocking drug and is an effective and safe drug for the treatment of a variety of hyperkinetic movement disorders. Molecular formula: C19H27NO4. Mole weight: 333.42. | |
| (2R,3R,11bS)-Dihydrotetrabenazine | (2R,3R,11bS)-Dihydrotetrabenazine is an impurity of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: Tetrabenazine Related Impurity 8 (2R,3R,11bS); (2R,3R,11bS)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11bhexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol. Grades: 98%. CAS No. 862377-29-5. Molecular formula: C19H29NO3. Mole weight: 319.44. | |
| (2R,3S,11bR)-Dihydrotetrabenazine | (2R,3S,11bR)-Dihydrotetrabenazine is an impurity of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: (2R,3S,11bR)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol; Tetrabenazine Related Impurity 11 (2R,3S,11bR); (2R,3S,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11bhexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol. Grades: 98%. CAS No. 862377-31-9. Molecular formula: C19H29NO3. Mole weight: 319.44. | |
| (2R,3S,11bS)-Dihydrotetrabenazine | (2R,3S,11bS)-Dihydrotetrabenazine is an impurity of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: (2R,3S,11bS)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol; (2R,3S,11bS)-DHTBZ; (2R,3S,11bS)-3-Isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol; cis(2,3)-Dihydro Tetrabenazine; Tetrabenazine Related Impurity 7 (2R,3S,11bS). Grades: 98%. CAS No. 924854-62-6. Molecular formula: C19H29NO3. Mole weight: 319.44. | |
| (2S,3R,11bS)-Dihydrotetrabenazine | (2S,3R,11bS)-Dihydrotetrabenazine is an impurity of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: Tetrabenazine Related Impurity 10 (2S,3R,11bS); (2S,3R,11bS)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol; (2S,3R,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-ol; RU 346. Grades: ≥95%. CAS No. 862377-33-1. Molecular formula: C19H29NO3. Mole weight: 319.44. | |
| (2S,3S,11bR)-Dihydrotetrabenazine | (2S,3S,11bR)-Dihydrotetrabenazine is an impurity of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: RU 350; (2S,3S,11bR)-9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-ol; trans (2,3)-Dihydro Tetrabenazine; (2S,3S,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11bhexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol; Tetrabenazine Related Impurity 9 (2S,3S,11bR). Grades: 98%. CAS No. 862377-27-3. Molecular formula: C19H29NO3. Mole weight: 319.44. | |
| (+)-α-Dihydrotetrabenazine | (+)-α-Dihydrotetrabenazine is an impurity of Tetrabenazine, which is a VMAT-2 inhibitor and has been found to be effective in the treatment of hyperkinetic movement disorder at some extent. Synonyms: [2R-(2α,3β,11bβ)]-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol; (+)-(2R,3R,11bR)-Dihydrotetrabenazine; (+)-DTBZ; (+)-Dihydrotetrabenazine; (2R,3R,11bR)-DHTBZ; Tetrabenazine Related Impurity 27(2R,3R,11bR); (+-)-3c-Isobutyl-9,10-dimethoxy-(11br)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isochinolin-2t-ol; trans-2 hydroxy-3 isobutyl-9,10 dimethoxy-1,2,3,4,6,7 hexahydro-11bH-benzo(a)quinolizine; 2H-Benzo[a]quinolizin-2-ol,1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-,(2R,3R,11bR); dihydrotetrabenazine, (2alpha, 3beta, 11bbeta)-isomer; TBZOH cpd. Grades: ≥ 95%. CAS No. 85081-18-1. Molecular formula: C19H29NO3. Mole weight: 319.44. | |
| (+)-β-Dihydrotetrabenazine | (+)-β-Dihydrotetrabenazine is a potent inhibitor of vascular monoamine transporter 2 (VMAT2) and an agent of significant interest for therapeutic and molecular imaging applications. Synonyms: (2S,3R,11bR)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol; (2S,3R,11bR)-Dihydrotetrabe; Tetrabenazine Related Impurity 6(2S,3R,11bR). Grades: ≥95%. CAS No. 924854-60-4. Molecular formula: C19H29NO3. Mole weight: 319.44. | |
| Valbenazine | Valbenazine is a potent and highly selective vesicular monoamine transporter 2(VMAT2) inhibitor. It is a prodrug of the (+)-α isomer of tetrabenazine for tardive syndrome therapy. It is effective in regulating the levels of dopamine release during nerve communication, while at the same time having minimal impact on the other monoamines. It significantly improved tardive dyskinesia and was well tolerated in patients. It is an experimental drug being investigated for use in the treatment of tardive dyskinesia and Tourette syndrome. It was developed by Neurocrine Biosciences. Uses: Valbenazine is an experimental drug being investigated for use in the treatment of tardive dyskinesia and tourette syndrome. Synonyms: Ingrezza; L-Valine, (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo(a)quinolizin-2-yl ester; (S)-2-amino-3-methyl-butyric acid (2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl ester; Tetrabenazine Related Impurity 28 (2R, 3R, 11bR, L-Val); [(2R,3R,11bR)-9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl] (2S)-2-amino-3-methylbutanoate; NBI-98854; NBI98854; MT-5199; MT5199; NBI 98854; MT 5199. Grades: >98%. CAS No. 1025504-45-3. Molecular formula: C24H38N2O4. Mole weight: 418.57. | |
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