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| Product | Description | |
|---|---|---|
| tetrahydromethanopterin S-methyltransferase | Involved in the formation of methane from CO in Methanobacterium thermoautotrophicum. Methanopterin is a pterin analogue. The reaction involves the export of one or two sodium ions in Archaea. Group: Enzymes. Synonyms: tetrahydromethanopterin methyltransferase. Enzyme Commission Number: EC 2.1.1.86. CAS No. 103406-60-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1987; tetrahydromethanopterin S-methyltransferase; EC 2.1.1.86; 103406-60-6; tetrahydromethanopterin methyltransferase. Cat No: EXWM-1987. |  |
| 5,6,7,8-tetrahydromethanopterin hydro-lyase | Found in methylotrophic bacteria and methanogenic archaea. Group: Enzymes. Synonyms: formaldehyde-activating enzyme. Enzyme Commission Number: EC 4.2.1.147. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4988; 5,6,7,8-tetrahydromethanopterin hydro-lyase; EC 4.2.1.147; formaldehyde-activating enzyme. Cat No: EXWM-4988. | |
| formylmethanofuran-tetrahydromethanopterin N-formyltransferase | Methanofuran is a complex 4-substituted furfurylamine and is involved in the formation of methane from CO2 in Methanobacterium thermoautotrophicum. Group: Enzymes. Synonyms: formylmethanofuran-tetrahydromethanopterin formyltransferase; formylmethanofuran: tetrahydromethanopterin formyltransferase; N-formylmethanofuran(CHO-MFR):tetrahydromethanopterin(H4MPT) formyltransferase; FTR; formylmethanofuran:5,6,7,8-tetrahydromethanopterin N5-formyltransferase. Enzyme Commission Number: EC 2.3.1.101. CAS No. 105669-83-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2040; formylmethanofuran-tetrahydromethanopterin N-formyltransferase; EC 2.3.1.101; 105669-83-8; formylmethanofuran-tetrahydromethanopterin formyltransferase; formylmethanofuran: tetrahydromethanopterin formyltransferase; N-formylmethanofuran(CHO-MFR):tetrahydromethanopterin(H4MPT) formyltransferase; FTR; formylmethanofuran:5,6,7,8-tetrahydromethanopterin N5-formyltransferase. Cat No: EXWM-2040. | |
| 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase | Contains one zinc atom and one iron atom per subunit of the dodecameric enzyme. It hydrolyses 7,8-dihydroneopterin 2',3'-cyclic phosphate, a step in tetrahydromethanopterin biosynthesis. In vitro the enzyme forms 7,8-dihydroneopterin 2'-phosphate and 7,8-dihydroneopterin 3'-phosphate at a ratio of 4:1. Group: Enzymes. Synonyms: MptB. Enzyme Commission Number: EC 3.1.4.56. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3739; 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase; EC 3.1.4.56; MptB. Cat No: EXWM-3739. | |
| 7,8-dihydropterin-6-yl-methyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate synthase | The enzyme, which has been studied in the archaeon Methanocaldococcus jannaschii, is involved in the biosynthesis of tetrahydromethanopterin. Group: Enzymes. Synonyms: MJ0301 (gene name); dihydropteroate synthase (ambiguous). Enzyme Commission Number: EC 2.5.1.105. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2721; 7,8-dihydropterin-6-yl-methyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate synthase; EC 2.5.1.105; MJ0301 (gene name); dihydropteroate synthase (ambiguous). Cat No: EXWM-2721. | |
| ANX-510 | ANX-510 is a folate-based biomodulator with potential antineoplastic activity. 5,10-methylenetetrahydrofolate (MTHF) stabilizes the covalent binding of the fluorouracil metabolite 5-5-fluoro-2'-deoxyuridine-5'-O-monophosphate (FdUMP) to its target enzyme, thymidylate synthase, which results in inhibition of thymidylate synthase, depletion of thymidine triphosphate (TTP), a necessary constituent of DNA, and tumor cell death. Synonyms: 5,10-Methylenetetrahydrofolic acid; 5,10-Methylene-tetrahydrofolate; Tetrahydromethylenefolate; N-{4-[3-amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl}-L-glutamic acid. CAS No. 3432-99-3. Molecular formula: C20H23N7O6. Mole weight: 457.44. |  |
| β-ribofuranosylphenol 5'-phosphate synthase | The enzyme is involved in biosynthesis of tetrahydromethanopterin in archaea. It was initially thought to use 4-aminobenzoate as a substrate, but was later shown to utilize 4-hydroxybenzoate. The activity is dependent on Mg2+ or Mn2+. Group: Enzymes. Synonyms: β-RFAP synthase (incorrect); β-RFA-P synthase (incorrect); AF2089 (gene name); MJ1427 (gene name); β-ribofuranosylhydroxybenzene 5'-phosphate synthase; 4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate synthase (incorrect); β-ribofuranosylaminobenzene 5'-phosphate synthase (incorrect); 5-phospho-α-D-ribose 1-diphosphate:4-aminobenzoate 5-phospho-β-D-rib. Enzyme Commission Number: EC 2.4.2.54. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2684; β-ribofuranosylphenol 5'-phosphate synthase; EC 2.4.2.54; β-RFAP synthase (incorrect); β-RFA-P synthase (incorrect); AF2089 (gene name); MJ1427 (gene name); β-ribofuranosylhydroxybenzene 5'-phosphate synthase; 4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate synthase (incorrect); β-ribofuranosylaminobenzene 5'-phosphate synthase (incorrect); 5-phospho-α-D-ribose 1-diphosphate:4-aminobenzoate 5-phospho-β-D-ribofuranosyltransferase (decarboxylating) (incorrect). Cat No: EXWM-2684. | |
| dihydromethanopterin reductase (acceptor) | This archaeal enzyme catalyses the last step in the biosynthesis of tetrahydromethanopterin, a coenzyme used in methanogenesis. The enzyme, characterized from the archaea Methanosarcina mazei and Methanocaldococcus jannaschii, is an iron-sulfur flavoprotein. cf. EC 1.5.1.47, dihydromethanopterin reductase [NAD(P)+]. Group: Enzymes. Synonyms: DmrX. Enzyme Commission Number: EC 1.5.99.15. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1569; dihydromethanopterin reductase (acceptor); EC 1.5.99.15; DmrX. Cat No: EXWM-1569. | |
| dihydromethanopterin reductase [NAD(P)+] | The enzyme, characterized from the bacterium Methylobacterium extorquens, is involved in biosynthesis of dephospho-tetrahydromethanopterin. The specific activity with NADH is 15% of that with NADPH at the same concentration. It does not reduce 7,8-dihydrofolate (cf. EC 1.5.1.3, dihydrofolate reductase). Group: Enzymes. Synonyms: DmrA; H2MPT reductase; 5,6,7,8-tetrahydromethanopterin 5,6-oxidoreductase; dihydromethanopterin reductase. Enzyme Commission Number: EC 1.5.1.47. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1528; dihydromethanopterin reductase [NAD(P)+]; EC 1.5.1.47; DmrA; H2MPT reductase; 5,6,7,8-tetrahydromethanopterin 5,6-oxidoreductase; dihydromethanopterin reductase. Cat No: EXWM-1528. | |
| tetrahydrosarcinapterin synthase | This enzyme catalyses the biosynthesis of 5,6,7,8-tetrahydrosarcinapterin, a modified form of tetrahydromethanopterin found in the Methanosarcinales. It does not require K+, and does not discriminate between ATP and GTP. Group: Enzymes. Synonyms: H4MPT:α-L-glutamate ligase; MJ0620; MptN protein. Enzyme Commission Number: EC 6.3.2.33. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5750; tetrahydrosarcinapterin synthase; EC 6.3.2.33; H4MPT:α-L-glutamate ligase; MJ0620; MptN protein. Cat No: EXWM-5750. | |
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