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| Product | Description | |
|---|---|---|
| Tetraxetan | Tetraxetan (DOTA) is a macrocyclic chelating agent. Tetraxetan can form stable coordination complexes with a variety of metal ions (e.g., 68Ga, 111In, 177Lu). Tetraxetan can be conjugated with targeting molecules (e.g., RGD peptide, folic acid) to enable the complex to target specific biomolecules or cells. Tetraxetan can be used for imaging studies of tumors, including melanoma and folate receptor-positive tumors (e.g., cervical cancer) [1][2][3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DOTA. CAS No. 60239-18-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 1 g. Product ID: HY-W053583. |  |
| Tetraxetan | Tetraxetan. Group: Biochemicals. Grades: Highly Purified. CAS No. 60239-18-1. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences. |  Worldwide |
| Rofapitide tetraxetan | Rofapitide tetraxetan (FAP-2286) is a potent and selective FAP-binding peptide with a mean IC 50 value of 2.7 nM for binding to FAP. Rofapitide tetraxetan can be labeled with radionuclides for diagnostic applications. Rofapitide tetraxetan has antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FAP-2286. CAS No. 2581741-18-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-147057. | |
| Satoreotide Tetraxetan | Satoreotide Tetraxetan is a somatostatin receptor 2 (SSTR2) antagonist. Satoreotide Tetraxetan, commonly labeled by 68Ga, is used for paired imaging in neuroendocrine tumors (NETs) research. Synonyms: DOTA satoreotide; Satoreotide DOTA; DOTA-JR-11; DOTA-JR11. CAS No. 1039726-31-2. Molecular formula: C74H98ClN19O21S2. Mole weight: 1689.27. |  |
| Vipivotide tetraxetan | Vipivotide tetraxetan is a human prostate-specific membrane antigen (PSMA)-targeting ligand that binds to PSMA-expressing tumor cells. Vipivotide tetraxetan could be labeled with 177Lu for imaging and detecting tumors. Uses: Vipivotide tetraxetan has been used in prostate cancer research, and is a promising prostate-specific membrane antigen-targeted theranostic agent. Synonyms: PSMA-617; PSMA 617; PSMA617; Glu-NH-CO-NH-Lys[(2-Nal)-Amc-DOTA]. Grade: >98.0%. CAS No. 1702967-37-0. Molecular formula: C49H71N9O16. Mole weight: 1042.14. | |
| Vipivotide tetraxetan | Vipivotide tetraxetan (PSMA-617) is a high potent prostate-specific membrane antigen (PSMA) inhibitor, with a K i of 0.37 nM. Vipivotide tetraxetan (PSMA-617) is designed consisting of three components: the pharmacophore Glutamate-urea-Lysine, the chelator DOTA able to complex both 68Ga or 177Lu, and a linker connecting these two entities. Glutamate-urea-Lysine is the selective pharmacophore to bind to prostate specific membrane antigen. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PSMA-617. CAS No. 1702967-37-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-117410. | |
| DOTA | Bifunctional DOTA aconjugates to peptides and has become an established strategy for constructing target-specific metal containing agents including targeted MRI contrast agents and diagnostic and therapeutic radiopharmaceuticals. Group: Biochemicals. Alternative Names: 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid; 1,4,7,10-Tetra(carboxymethyl)-1,4,7,10-tetraazacyclododecane; 1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid; DOTA; NSC 681107; Tetraxetan. Grades: Highly Purified. CAS No. 60239-18-1. Pack Sizes: 100mg, 250mg, 500mg. US Biological Life Sciences. | Worldwide |
| Europium DOTA Sodium Salt Hydrate | Bifunctional DOTA derivatives and their conjugation to peptides has become an established strategy for constructing target-specific metal containing agents including targeted MRI contrast agents and diagnostic and therapeutic radiopharmaceuticals. Group: Biochemicals. Alternative Names: 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid Europium Sodium Salt Hydrate; Europium 1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic Acid Sodium Salt Hydrate; Eu-DOTA; NSC 681107-Eu; Eu-Tetraxetan Sodium Salt Hydrate. Grades: Highly Purified. CAS No. Free Acid: 60239-18-1. Pack Sizes: 10mg. Molecular Formula: C??H??EuN?NaO? xH?O. US Biological Life Sciences. | Worldwide |
| Gadobutrol Impurity 1 | Gadobutrol Impurity 1 is an impurity of Gadobutrol, which is a nonionic, paramagnetic contrast agent developed for tissue contrast enhancement in magnetic resonance imaging (MRI). Uses: Chelating agents. Synonyms: DOTA; Tetraxetan; 60239-18-1; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid; Dota acid; 1,4,7,10-Dota; 1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid; 2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetic acid; CHEBI:61028; DOT-A; 2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetic acid; MFCD00068657; NSC-681107; 1HTE449DGZ; MLS001333612; Tetraxetan (USAN); NSC681107; 2,2',2',2'''-(1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetryl)tetraacetic acid; SMR000857276; TETRAXETAN [USAN]; 2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl]acetic acid; UNII-1HTE449DGZ; tetraxetanum; gadoterate-meglumine; 1,4,7,10-Tetraazacyclododecane- 1,4,7,10-tetraacetic-acid; Gadobutrol impurity 1. Grade: > 95%. Molecular formula: C18H34N4O9. Mole weight: 450.49. | |
| Gadobutrol Impurity 9 | Gadobutrol Impurity 9 is an impurity of Gadobutrol, which is a nonionic, paramagnetic contrast agent developed for tissue contrast enhancement in magnetic resonance imaging (MRI). Synonyms: DOTA; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid; 1,4,7,10-Tetra(carboxymethyl)-1,4,7,10-tetraazacyclododecane; 1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid; NSC 681107; Tetraxetan. Grade: > 95 %. CAS No. 60239-18-1. Molecular formula: C16H28N4O8. Mole weight: 404.42. | |
| JUN68744 | JUN68744 is a useful peptide linker for synthesis of PSMA-617 (vipivotide tetraxetan), which is a ligand used to make 177Lu-PSMA-617, a radioactive molecule to fight cancer. PSMA-617 originally was developed at the German Cancer Research Center and the Heidelberg University Hospital. ABX held the exclusive license to bring the treatment, which targets prostate-specific membrane antigen (PSMA), through early clinical development. Synonyms: JUN-68744; JUN 68744; PSMA-617-linker; PSMA 617-linker; PSMA617-linker; Vipivotide tetraxetan Linker; (((S)-5-((S)-2-((1r,4S)-4-(aminomethyl)cyclohexane-1-carboxamido)-3-(naphthalen-2-yl)propanamido)-1-carboxypentyl)carbamoyl)-L-glutamic acid. CAS No. 1703768-74-4. Molecular formula: C33H45N5O9. Mole weight: 655.74. | |
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