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| Product | Description | |
|---|---|---|
| Thiocolchicine | A muscle relaxant. Group: Biochemicals. Alternative Names: N-[(7S)-5,6,7,9-Tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide; 10-Thio-colchicine; 10-Demethoxy-10- (methylthio) colchicine; NSC 186301. Grades: Highly Purified. CAS No. 2730-71-4. Pack Sizes: 100mg. US Biological Life Sciences. |  Worldwide |
| Thiocolchicine | Thiocolchicine, a derivative modified in the C Ring of Colchicine (HY-16569) with enhanced biological properties. Thiocolchicine is a potent inhibitor of tubulin polymerization ( IC 50 =2.5 μM) and competitively binds to tubulin with a K i of 0.7 μM. Thiocolchicine induces cell apoptosis [1] [2]. Thiocolchicine can be used as an ADC cytotoxin in ADC technology. Uses: Scientific research. Group: Signaling pathways. CAS No. 2730-71-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116852. |  |
| Thiocolchicine | Thiocolchicine is a potent tubulin polymerization and microtubule assembly inhibitor, a axonal cytoskeleton modulator and apoptosis inducer. Structurally, thiocolchicine is a colchicine analog in which the C-10 methoxy is replaced with a thiomethyl moiety. Thiocolchicine was shown to bind with high affinity to the colchicine site on tubulin. Thiocolchicine-dimers were shown to be potent topoisomerase I inhibitors. Synonyms: N-[(7S)-5,6,7,9-Tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide; 10-Thio-colchicine; 10-Demethoxy-10-(methylthio)colchicine; NSC 186301. Grades: 98%. CAS No. 2730-71-4. Molecular formula: C22H25NO5S. Mole weight: 415.50. |  |
| Thiocolchicine | Thiocolchicine. Uses: For analytical and research use. Group: Impurity standards. CAS No. 602-41-5. Molecular Formula: C27H33NO10S. Mole Weight: 563.62. Catalog: APB602415. |  |
| Thiocolchicine Impurity | Thiocolchicine Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 97043-09-9. Molecular Formula: C19H21NO4S. Mole Weight: 359.44. Catalog: APB97043099. | |
| Thiocolchicine (NSC 186301, 10-Demethoxy-10-methylthiocolchicine) | An antimitotic alkaloid. Tubulin polymerization and microtubule assembly inhibitor and axonal cytoskeleton modulator; apoptosis inducer. Thiocolchicine-dimers were shown to be potent topoisomerase I inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 2730-71-4. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| 2-Demethyl thiocolchicine | 2-Demethyl thiocolchicine. Group: Biochemicals. Alternative Names: N-[(7S)-5,6,7,9-Tetrahydro-2-hydroxy-1,3-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide; NSC 369937. Grades: Highly Purified. CAS No. 87424-26-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C21H23NO5S. US Biological Life Sciences. | Worldwide |
| 3-Demethyl thiocolchicine | 3-Demethyl thiocolchicine. Group: Biochemicals. Alternative Names: N-[(7S)-5,6,7,9-Tetrahydro-3-hydroxy-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide; 2-Demethylthio-colchicine; 3-De methyl thiocolchicine. Grades: Highly Purified. CAS No. 87424-25-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C21H23NO5S. US Biological Life Sciences. | Worldwide |
| 3-Demethyl Thiocolchicine | 3-Demethyl Thiocolchicine is a Thiocolchicine metabolite, used in therapy as an antitunor, antiinflammatory and immunosuppressive agent. Synonyms: N-[(7S)-5,6,7,9-Tetrahydro-3-hydroxy-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide; 2-Demethylthio-colchicine; 3-Demethylthiocolchicine; 3-Desmethylthiocolchicine; 3-O-Demethylthiocolchicine; NSC 361792. Grades: > 95%. CAS No. 87424-25-7. Molecular formula: C21H23NO5S. Mole weight: 401.48. | |
| 3-Demethyl thiocolchicine 2-O-(2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester) | 3-Demethyl thiocolchicine 2-O-(2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester) is a potent derivative of thiocolchicine, a natural compound derived from the Colchicum autumnale plant. It exhibits anti-cancer properties by inhibiting microtubule formation, consequently disrupting cell division. Synonyms: (7S)-7-(Acetylamino)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-3-yl 2,3,4-tri-O-acetyl-b-D-glucopyranosiduronic acid methyl ester. CAS No. 250662-47-6. Molecular formula: C34H39NO14S. Mole weight: 717.74. | |
| 3-Demethyl Thiocolchicine 2-O-(2,3,4-Tri-O-acetyl- β-D-glucuronide Methyl Ester) | Protected metabolite of Thiocolchicoside (TCC). Group: Biochemicals. Alternative Names: (7S)-7-(Acetylamino)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-3-yl 2,3,4-Tri-O-acetyl- β-D-glucopyranosiduronic Acid Methyl Ester. Grades: Highly Purified. CAS No. 250662-47-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 3-Demethyl Thiocolchicine 3-O-β-D-Glucuronide | 3-Demethyl Thiocolchicine 3-O-β-D-Glucuronide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 819802-34-1. Molecular Formula: C27H31NO11S. Mole Weight: 577.6. Catalog: APB819802341. | |
| 3-Demethyl Thiocolchicine-d3 | A Thiocolchicine metabolite, used in therapy as an antitunor, antiinflammatory and immunosuppressive agent. Group: Biochemicals. Alternative Names: N-[(7S)-5,6,7,9-Tetrahydro-3-hydroxy-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide-d3; 2-Demethylthio-colchicine-d3; 3-Demethylthiocolchicine-d3; 3-Des methyl thiocolchicine-d3; 3-O-Demethylthiocolchicine-d3; NSC 361792-d3. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 3-Demethyl Thiocolchicine-D3 | 3-Demethyl Thiocolchicine-D3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246818-03-0. Molecular Formula: C21H20D3NO5S. Mole Weight: 404.5. Catalog: APB1246818030. | |
| 3-Demethyl Thiocolchicine-d3 2-O-(2,3,4-Tri-O-acetyl- β-D-glucuronide Methyl Ester) | Protected metabolite of labeled Thiocolchicoside (TCC). Group: Biochemicals. Alternative Names: (7S)-7-(Acetylamino)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-3-yl-d3 2,3,4-Tri-O-acetyl- β-D-glucopyranosiduronic Acid Methyl Ester. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 3-Demethyl Thiocolchicine-d3 3-O- β-D-Glucuronide | The major labeled metabolite of Thiocolchicoside (TCC), a muscle relaxant drug. Group: Biochemicals. Alternative Names: 7S)-7-(Acetylamino-d3)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-3-yl β-D-Glucopyranosiduronic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 9-Thiomethyl Thiocolchicine | Thiocolchicine derivative. Group: Biochemicals. Alternative Names: N-[ (7S) -5, 6, 7, 9-Tetrahydro-1, 2, 3-trimethoxy-10- (methylthio) -9- (thiomethyl) benzo[a]heptalen-7-yl]acetamide; 10-Thio-9-thiomethyl-colchicine. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| N-Desacetyl 3-Demethyl Thiocolchicine | Thiocolchicine derivative. Group: Biochemicals. Alternative Names: (7S)-7-Amino-6,7-dihydro-3-hydroxy-1,2-dimethoxy-10-(methylthio)-benzo[a]heptalen-9(5H)-one. Grades: Highly Purified. CAS No. 97043-09-9. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| (S)-2-Chloroacetyl-2-demethyl thiocolchicine | (S)-2-Chloroacetyl-2-demethyl thiocolchicine. Group: Biochemicals. Alternative Names: Chloroacetic acid (7S)-7-(acetylamino)-5,6,7,9-tetrahydro-1,3-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-2-yl ester. Grades: Highly Purified. CAS No. 148731-67-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C23H24ClNO6S. US Biological Life Sciences. | Worldwide |
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