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| Product | Description | |
|---|---|---|
| Thioguanine | Thioguanine incorporation alters the DNA cleavage induced by topoisomerase II in the presence and absence of etoposide. Uses: Antimetabolites, antineoplastic. Synonyms: thioguanine|6-Thioguanine|154-42-7|Tioguanine|2-Amino-6-mercaptopurine|6-Mercaptoguanine|Tioguanin|Tabloid|2-Amino-6-purinethiol|Lanvis|2-Amino 6MP|2-Aminopurin-6-thiol|2-Aminopurine-6-thiol|2-Aminopurine-6(1H)-thione|Wellcome U3B|6-Mercapto-2-aminopurine|2-Amino-9H-purine-6-thiol|6-TG|2-Amino-6-merkaptopurin|Tioguaninum|Guanine, thio-|Tioguanina|6H-Purine-6-thione, 2-amino-1,7-dihydro-|2-Amino-1,7-dihydro-6H-purine-6-thione|BW 5071|Purine-6-thiol, 2-amino-|Purine-6(1H)-thione, 2-amino-|2-Amino-1,9-Dihydro-6h-Purine-6-Thione|NSC-752|Thioguanine Anhydrous|TG|Thioguanine Hemihydrate|THG|NSC 752|2-Amino-1,7-dihydro-6H-purin-6-thion|X 27|UNII-WIX31ZPX66|Tioguanine (INN)|Thioguanine, anhydrous|9H-Purine-6-thiol, 2-amino-|2-amino-1, 9-dihydropurine-6-thione|CHEMBL727|WIX31ZPX66|2-amino-3, 7-dihydro-6H-purine-6-thione|2-amino-6, 7-dihydro-3H-purine-6-thione|CHEBI: 9555|NSC752|Thioguanine2-Amino-6-purinethiol|2-Thioguanine|2-amino-1H-purine-6(9H)-thione|Tioguanine [INN] |2-amino-1, 7-di hydropurine-6-thione|NCGC00094792-01|DSSTox_CID_3652|2-Amino-6-MP|DSSTox_RID_77129|DSSTox_GSID_2365 2|Tioguaninum [INN-Latin]|.. Grades: >98%. CAS No. 154-42-7. Molecular formula: C5H5N5S. Mole weight: 167.19. |  |
| Thioguanine | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsapi standardsimpurity standardspharmaceutical toxicology. Alternative Names: 2-Amino-3,7-dihydropurine-6-thione, Thioguanine Tabloid, Purine-6(1H)-thione, 2,3-dihydro-2-imino- (6CI), Tabloid, Tioguanine, Purine-6-thiol, 2-amino- (8CI), 6-Mercaptoguanine, 2-Amino-9H-purine-6(1H)-thione, Tioguanin, 2-Aminopurine-6-thiol, Purine-6(1H)-thione, 2-amino- (7CI,8CI),6H-Purine-6-thione, 2-amino-1,9-dihydro-, Lanvis, NSC 76504, 2-Amino-6-mercaptopurine, Thioguanine, NSC 752, 6H-Purine-6-thione, 2-amino-1,7-dihydro- (9CI), 2-Amino-9H-purine-6-thiol, 6-TG, Guanine, thio-, 6-Thioguanine. |  |
| 2-Amino-6-hydroxy-8-mercaptopurine (8-Mercaptoguanine, 8-Thioguanine) | 2-Amino-6-hydroxy-8-mercaptopurine (8-Mercaptoguanine, 8-Thioguanine). Group: Biochemicals. Alternative Names: 8-Mercaptoguanine, 8-Thioguanine. Grades: Highly Purified. Pack Sizes: 2.5g. US Biological Life Sciences. |  Worldwide |
| 2-Amino-6-mercaptopurine (2-Amino-1,7(9)-dihydro-purine-6-thione, Tioguanine, 6-Thioguanine,. 2-Amino-9H-purine-6-thiol) | The compound produces dose-dependent inhibition of stimulated expression of TRAIL protein. Group: Biochemicals. Alternative Names: 2-Amino-1,7(9)-dihydro-purine-6-thione; Tioguanine; 6-Thioguanine;2-Amino-9H-purine-6-thiol. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 2-Amino-6-purinethiol (6-Thioguanine) | 1g Pack Size. Group: Analytical Reagents, Bioactive Small Molecules. Formula: C5H5N5S. CAS No. 154-42-7. Prepack ID 66238710-1g. Molecular Weight 167.19. See USA prepack pricing. |  |
| 6-Methylthioguanine | A metabolite of 2-Deoxy-6-thio Guanosine and 6-Thioguanine. An effective immunosuppressant and anticancer agent, however chronic exposure can be mutagenic in human cells as long-term use of thiopurines was found to be associated with a significantly increased risk of various types of cancer. Group: Biochemicals. Alternative Names: 6-(Methylthio)-1H-purin-2-amine; 2-Amino-6-methylmercaptopurine; NSC 29420; 2-Amino-6-methylthiopurine; S-Methyl-6-thioguanine; S6-Methyl-6-thioguanine. Grades: Highly Purified. CAS No. 1198-47-6. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 6-Thioguanine | 6-Thioguanine. Group: Biochemicals. Grades: Purified. CAS No. 154-42-7. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 6-Thioguanine | 6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases ( PLpros ) and also potently inhibits USP2 activity, with IC 50 s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively. Uses: Scientific research. Group: Natural products. Alternative Names: Thioguanine; 2-Amino-6-purinethiol. CAS No. 154-42-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-13765. |  |
| 6-Thioguanine | 6-Thioguanine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-Mercaptoguanine; Thioguanine; thio-guanin; 6-tg; 6-Thioguanine; wellcomeu3b; 2-amino-1,7-dihydro-6H-purine-6-thione; 2-aminomercaptopurine; 2-Amino-6-mercaptopurine; 2-Amino-1H-purine-6(7H)-thione; THIOGUANINE; 2-amino-9H-purine-6(1H)-thione; 6-thioguan. Product Category: Heterocyclic Organic Compound. Appearance: Odorless or almost odorless pale yellow crystalline powder. CAS No. 154-42-6. Molecular formula: C5H5N5S. Mole weight: 167.192. Purity: 0.96. IUPACName: tioguanine. Density: 2.08 g/cm³. Product ID: ACM154426. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 6-Thioguanine 98+% | 6-Thioguanine 98+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 154-42-7. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. | Worldwide |
| 6-Thioguanine (Standard) | 6-Thioguanine (Standard) is the analytical standard of 6-Thioguanine. This product is intended for research and analytical applications. 6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases ( PLpros ) and also potently inhibits USP2 activity, with IC 50 s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively. Uses: Scientific research. Group: Natural products. CAS No. 154-42-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13765R. | |
| 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-6-thioguanine (FANA-thioG) | 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-6-thioguanine (FANA-thioG) is a remarkable and cutting-edge compound, exhibiting its profound impact in research of both antiviral and anticancer domains. By impeding the process of DNA enhancement, FANA-thioG effectively curbs the propagation of malignant cells and the replication of viruses. Grades: ≥ 97%. Molecular formula: C10H12FN5O3S. Mole weight: 301.2974. | |
| 2-Amino-6-hydroxy-8-mercaptopurine | 2-Amino-6-hydroxy-8-mercaptopurine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-AMINO-6-HYDROXY-8-THIOPURINE;8-THIOGUANINE;8-MERCAPTOGUANINE;2-AMINO-6-HYDROXY-8-MERCAPTOPURINE 97%;2-Amino-6-hydroxy-8-mercaptopurine,97%. Product Category: Heterocyclic Organic Compound. Appearance: YELLOW FINE CRYSTALLINE POWDER. CAS No. 28128-40-7. Molecular formula: C5H5N5OS. Mole weight: 183.19. Product ID: ACM28128407. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2-Amino-6-mercaptopurine-13C2,15N | A labeled Tioguanine. The compound produced dose-dependent inhibition of stimulated expression of TRAIL protein. Group: Biochemicals. Alternative Names: 2-Amino-1,7(9)-dihydro-purine-6-thione-13C2,15N; Tioguanine-13C2,15N; 6-Thioguanine-13C2,15N; 2-Amino-9H-purine-6-thiol-13C2,15N. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 2'-Deoxy-6-thio Guanosine | Guanosine derivative with cancer chemotherapeutic properties. It is involved in the inhibition of human RNase H-mediated RNA cleavage from DNA-RNA duplexes via incorporation into DNA. Group: Biochemicals. Alternative Names: 2-Amino-9-(2-deoxy- β-D-erythro-pentofuranosyl)-9H-purine-6(1H)-thione; 2-Amino-9-(2-deoxy- β-D-erythro-pentofuranosyl)-6-mercaptopurine; 2'-Deoxythioguanosine; 2'-Desoxy-6-thioguanosine; NSC 71261; TGdR; Thioguanine Deoxyriboside; β-Thioguanine Deoxyriboside. Grades: Highly Purified. CAS No. 789-61-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 6-Thio-dG | 6-thio-dG is a nucleoside analog and telomerase substrate. Uses: Studies suggest that beta-tgdr is a latent form of tg. since resistance to antileukemic agent 6-thioguanine inevitably develops in animal tumors, this new agent beta-tgdr is of potential clinical use. Synonyms: 6-Thio-2'-Deoxyguanosine; 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purine-6(1H)-thione; 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6-mercaptopurine; 2'-Deoxythioguanosine; 2'-Desoxy-6-thioguanosine; NSC 71261; TGdR; Thioguanine Deoxyriboside; β-Thioguanine Deoxyriboside. Grades: ≥97% by HPLC. CAS No. 789-61-7. Molecular formula: C10H13N5O3S. Mole weight: 283.31. | |
| CI-898 hydrochloride | CI-898 is a lipophilic antifolate inhibitor of dihydrofolate reductase (DHFR). The presence of the cofactor NADPH enhances bind of CI-898 and DHFR. CI-898 inhibits growth and halts the cell cycle at the G1/S phase in L1210 mouse lymphocytic leukemia cells and is active against methotrexate-resistant cancer cell lines. It also inhibits the growth of S. faecalis and S. aureus when used at concentrations less than 0.25 μg/ml. It also enhances the activity of doxorubicin, cyclophosphamide, and 6-thioguanine in mice with advanced stage P338 leukemia. Synonyms: Trimetrexate; CI 898 trihydrochloride; Trimetrexate trihydrochloride; TMTX. Grades: ≥98%. CAS No. 1658520-97-8. Molecular formula: C19H23N5O3·3HCl. Mole weight: 478.80. | |
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