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Thioridazinehydrochloride, an orally active antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities. Thioridazinehydrochloride is also a potent inhibitor of PI3K-Akt-mTOR signaling pathways with anti-angiogenic effect. Thioridazinehydrochloride shows antiproliferative and apoptosis induction effects in various types of cancer cells, with specificity on targeting cancer stem cells (CSCs) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130-61-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0965.
Thioridazinehydrochloride
Thioridazinehydrochloride, an orally active antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities. Thioridazinehydrochloride is also a potent inhibitor of PI3K-Akt-mTOR signaling pathways with anti-angiogenic effect. Thioridazinehydrochloride shows antiproliferative and apoptosis induction effects in various types of cancer cells, with specificity on targeting cancer stem cells (CSCs). Group: Inhibitors. CAS No. 130-61-0. Molecular formula: C21H26N2S2.HCl. Mole weight: 407.03. Purity: >99 %. Catalog: ACM130610.
Thioridazinehydrochloride
Thioridazinehydrochloride is a dopamine receptor antagonist displaying antipsychotic activity. Thioridazine induces apoptosis via targeting the PI 3-K/Akt/mTOR/p70 S6K pathway, and induces G1 cell cycle arrest. Thioridazine exhibits anticancer activity in cervical, endometrial and breast cancer cells. Synonyms: 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride; Thioridazine HCl; Sonapax hydrochloride; Thioridazine chloride; Mellaril hydrochloride; 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, hydrochloride (1:1); 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, monohydrochloride; Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)-, hydrochloride; Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)-, monohydrochloride; 10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride; 2-Methylmercapto-10-[2-(N-methyl-2-piperidyl)ethyl]phenothiazine hydrochloride; Aldazine; Mallorol; Melleretten; Melleril; Melleril (tablet); Novoridazine; NSC 186060; Orsanil; Ridazin; Stalleril; Thioril; Thiozine. Grades: ≥99% by HPLC. CAS No. 130-61-0. Molecular formula: C21H26N2S2.HCl. Mole weight: 407.04.
ThioridazineHydrochloride
Thioridazine HCl is a dopamine receptor blocker and antipsychotic. It is the parent compound of sulforidazine and mesoridazine. Group: Biochemicals. Alternative Names: 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride; 2-Methylmercapto-10-[2- (N-methyl-2-piperidyl) ethyl]phenothiazine Hydrochloride; Aldazine; Mellaril; Orsanil; Ridazin; Stalleril. Grades: Highly Purified. CAS No. 130-61-0. Pack Sizes: 2.5g. US Biological Life Sciences.
2-(2-(2-(Methylthio)-10H-phenothiazin-10-yl)ethyl)piperidine-1-carbaldehyde is a metabolite of the extensively biotransformed piperidine type phenothiazine antipsychotic agent and dopamine receptor blocker, thioridazinehydrochloride (T368800). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 100mg. Molecular Formula: C21H24N2OS2. US Biological Life Sciences.
Labeled Thioridazine intermediate. Group: Biochemicals. Alternative Names: 2-(2-Chloroethyl)-1-methyl-piperidine-d3 Hydrochloride. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
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2- (2-Chloroethyl) -1-piperidinecarboxalde hyde
2- (2-Chloroethyl) -1-piperidinecarboxalde hyde is an constituent in the synthesis of phenothiazine antipsychotic agent and dopamine receptor blocker, thioridazinehydrochloride (T368800). Group: Biochemicals. Grades: Highly Purified. CAS No. 128183-77-7. Pack Sizes: 50mg, 250mg. Molecular Formula: C8H14ClNO. US Biological Life Sciences.
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2- (2- hydroxyethyl) -1-piperidinecarboxalde hyde
2- (2- hydroxyethyl) -1-piperidinecarboxalde hyde is an constituent in the synthesis of phenothiazine antipsychotic agent and dopamine receptor blocker, thioridazinehydrochloride (T368800). Group: Biochemicals. Grades: Highly Purified. CAS No. 84681-79-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H15NO2. US Biological Life Sciences.
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