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Thymidine 5'-triphosphate-3'-monophosphate, renowned for its indispensable role in DNA synthesis and DNA-based applications, assumes a paramount position within the biomedical sector. Revered as a pivotal precursor of DNA, this product proficiently facilitates a myriad of molecular biology techniques, including but not limited to PCR amplification, DNA sequencing, and cloning. Furthermore, it engenders invaluable assistance in unraveling the complexities of DNA replication, repair, and transcription, thereby contributing significantly to the realm of genetic disease and cancer investigations and therapeutics. CAS No. 1015762-49-8. Molecular formula: C10H18N2O17P4. Mole weight: 562.15.
Thymidine 5'-triphosphate lithium salt
Thymidine 5'-triphosphate lithium salt is an indispensable compound widely employed, holding immense significance in diverse applications for studying viral infections, genetic anomalies and neoplastic ailments. This paramount component assumes the role of a nucleotide foundational unit, indispensably participating in the replication and mending mechanisms of DNA. Synonyms: dTTP Li. Grades: ≥ 99% (HPLC). Molecular formula: C10H17N2O14P3·xLi. Mole weight: 482.17 (free acid).
Thymidine 5'-Triphosphate Sodium Salt
It is a metabolite of Thymidine. As well as a Thymidine analogue as phosphate donor. Synonyms: Thymidine 5'-(tetrahydrogen triphosphate) sodium salt; Deoxythymidine triphosphate sodium salt; Thymidine 5'-(tetrahydrogen triphosphate), sodium salt (1:x); TTP sodium salt. Grades: 95%. CAS No. 18423-43-3. Molecular formula: C10H17N2O14P3.xNa. Mole weight: 482.17 (free acid).
2',3'-Didehydro-3'-deoxy-thymidine-5'-triphosphate, lithium salt
2',3'-Didehydro-3'-deoxy-thymidine-5'-triphosphate, lithium salt is a critical compound used in the field of biomedicine. This product plays a vital role in molecular biology research, specifically in the study and development of antiviral therapies. It serves as a precursor for the synthesis of certain antiviral drugs, enabling researchers to target and combat various viral infections more effectively. Molecular formula: C10H11Li4N2O13P3. Mole weight: 487.88.
2-Deoxythymidine-5-Triphosphate, Sodium Salt (dTTP) Powder, BioGenomics
Suitable for use in PCR, cDNA synthesis, DNA sequencing and labeling procedures. Group: Biochemicals. Alternative Names: Thymidine 5'-(Tetrahydrogen Triphosphate) Sodium Salt; Thymidine-5-Triphosphate, Sodium Salt; dTTP; 2'-Deoxythymidine 5'-triphosphate trisodium salt. Grades: Molecular Biology Grade. CAS No. 18423-43-3. Pack Sizes: 25mg, 50mg, 100mg. Molecular Formula: C10H14N2O14P3Na3, Molecular Weight: 548.11. US Biological Life Sciences.
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2-Deoxythymidine-5-Triphosphate, Sodium Salt (dTTP) Solution, BioGenomics
PCR Grade nucleotides are specially manufactured and purified to the highest possible chemical purity. PCR Grade nucleotides contain at least 99% of the relevant deoxynucleoside-triphosphate (dNTP) and less than 0.9% deoxynucleoside-diphosphate (dNDP). Group: Biochemicals. Alternative Names: Thymidine 5'-(Tetrahydrogen Triphosphate) Sodium Salt; Thymidine-5-Triphosphate, Sodium Salt; dTTP; 2'-Deoxythymidine 5'-triphosphate trisodium salt. Grades: Molecular Biology Grade. CAS No. 18423-43-3Free acid: 365-08-2. Pack Sizes: 250ul, 1250ul. US Biological Life Sciences.
3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate is a precursor molecule used in the synthesis of custom DNA probes and primers. It is predominantly employed in applications to detect and amplify specific genetic sequences related to various diseases, such as cancer and infectious diseases. Synonyms: 3'-O-[(1-Methylethylidene)amino]-thymidine 5'-(tetrahydrogen triphosphate). CAS No. 1220515-68-3. Molecular formula: C13H22N3O14P3. Mole weight: 537.25.
4'-Azidothymidine 5-triphosphate
4'-Azidothymidine 5-triphosphate is a highly efficacious antiviral compound employed in the research of HIV/AIDS, functioning by impeding the vital reverse transcriptase enzyme responsible for viral replication. Notably, this nucleotide analogue possesses the remarkable ability to disturb the research and development of viral DNA, thereby impeding the pernicious virus from proliferating. Synonyms: Adrt-TP; Adrt 5'-triphosphate; 4'-AzidothymidineTP deriv.; 4'-azidothymidine triphosphate; 4-Azidothymidine 5-triphosphate; 4'-Azidothymidine 5'-triphosphate; [[(2R,3S,5R)-2-azido-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate; Thymidine 5'-(tetrahydrogen triphosphate),4'-azido-; 4'-Azidothymidine 5'-triphosphate4'-Azidothymidine 5'-triphosphate; [[(2R,3S,5R)-2-azido-3-hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate; 130108-94-0; Thymidine 5'-(tetrahydrogen triphosphate), 4'-azido-Thymidine 5'-(tetrahydrogen triphosphate), 4'-azido-Thymidine 5'-(tetrahydrogen triphosphate), 4'-azido-. CAS No. 140158-13-0. Molecular formula: C10H16N5O14P3. Mole weight: 523.18.
L-Thymidine-5'-triphosphate sodium salt
L-Thymidine-5'-triphosphate sodium salt. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences.
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L-Thymidine-5'-triphosphate sodium salt
L-Thymidine-5'-triphosphate sodium salt is a vital compound assuming the role of an indispensable substrate responsible for DNA synthesis. It is extensively employed in diverse research domains, encompassing the profound exploration of DNA replication, repair mechanisms and sequencing procedures. Molecular formula: C10H13N2Na4O14P3. Mole weight: 570.09.
Thymidine-13C10,15N2 5?-triphosphate sodium salt solution
?98 atom %, ?95% (CP), 100 mM in 5 mM Tris HCl. Group: Fluorescence/luminescence spectroscopy.
dTTP could be used in the studies of DNA labeling reactions, polymerase chain reaction and sequencing/cycle sequencing analysis. Synonyms: 2'-Deoxythymidine-5'-triphosphate trisodium salt; dTTP trisodium salt; Thymidine-5'-triphosphoric acid trisodium salt; sodium ((2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl hydrogentriphosphate; Thymidine 5'-(Tetrahydrogen Triphosphate) Sodium Salt. Grades: ≥95% by HPLC. CAS No. 27821-54-1. Molecular formula: C10H14N2O14P3.3Na. Mole weight: 548.11.
Thymidine-5-Triphosphate, Sodium Salt (dTTP), BioGenomics
Suitable for use in PCR, cDNA synthesis, DNA sequencing and labeling procedures. Thymidine 5?-triphosphate (dTTP) is one of the four natural deoxynucleotides, along with deoxyadenosine 5-triphosphate (dATP), deoxyguanosine 5-triphosphate (dGTP) and deoxycytosine 5-triphosphate (dCTP) used for the biosynthesis of deoxyribonucleic acids by DNA polymerases and reverse transcriptases. Deoxy-TTP may also be used as a substrate to study the specificity and kinetics of thymidine-triphosphatase(s) (EC 3.6.1.39) and other dTTP hydrolyzing activities. Group: Biochemicals. Alternative Names: Thymidine 5'-(Tetrahydrogen Triphosphate) Sodium Salt; Thymidine-5-Triphosphate, Sodium Salt; dTTP; 2'-Deoxythymidine 5'-triphosphate trisodium salt. Grades: Highly Purified. CAS No. 18423-43-3Free acid: 365-08-2. Pack Sizes: 25mg, 50mg, 100mg. US Biological Life Sciences.
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2'-F-dTTP
2'-F-dTTP is a modified nucleoside triphosphate that increases the stability of nucleases. Synonyms: 2'-Fluoro-thymidine-5'-Triphosphate. Grades: ≥95% by AX-HPLC. Molecular formula: C10H16N2O14P3F. Mole weight: 500.16.
5'-O-[Bis(4-methoxyphenyl)?phenylmethyl]?-3'-Thymidylic Acid Bis(2-cyanoethyl) Ester is an intermediate in synthesizing Thymidine 5'-Triphosphate, 3'-Phosphate Triethylamine Salt, a derivative of Thymidine 5'-Triphosphate which is used for the biosynthesis of deoxyribonucleic acids by DNA polymerases and reverse transcriptases. Synonyms: Bis(2-cyanoethyl) ((2R,3S,5R)-2-(Hydroxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl) Phosphate. CAS No. 76759-76-7. Molecular formula: C16H21N4O8P. Mole weight: 428.33.
AzTTP
AzTTP is a metabolite of Zidovudine that shows an anti-HIV activity in vivo. AzTTP inhibits reverse transcriptase, telomerase (IC50 = 80 μM) and thymidine phosphorylation. Synonyms: 3'-Azido-ddTTP; 3'-Azido-2',3'-dideoxythymidine-5'-Triphosphate; AZT-TP; Zidovudine Triphosphate; Azidothymidine Triphosphate. Grades: ≥ 95% by HPLC. CAS No. 906479-25-2. Molecular formula: C10H16N5O13P3 (free acid). Mole weight: 507.18 (free acid).
Stavudine 5'-triphosphate sodium salt
Stavudine 5'-triphosphate sodium salt. Group: Biochemicals. Alternative Names: 2',3'-Didehydro-2',3'-dideoxy-thymidine-5'-triphosphate sodium salt. Grades: Highly Purified. Pack Sizes: 100ug, 200ug. US Biological Life Sciences.
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Stavudine 5'-triphosphate sodium salt
Stavudine 5'-triphosphate sodium salt is a paramount constituent within the biomedical sector, aiding in studying viral infections instigated by the human immunodeficiency virus (HIV). Serving as an antiretroviral compound, it effectively hampers the HIV reverse transcriptase enzyme and thwarts viral reproduction. Synonyms: 2',3'-Didehydro-2',3'-dideoxy-thymidine-5'-triphosphate sodium salt. Molecular formula: C10H15N2O13P3·xNa. Mole weight: 464.15 (free acid).
Thymidine 5-diphosphate sodium
Thymidine 5-diphosphate (dTDP) sodium is the key product of pyrimidine synthesis in organisms. Thymidine 5-diphosphate sodium is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5-thymidine monophosphate (dTMP), which requires ATP and Mg 2+. Thymidine 5-diphosphate sodium is further catalyzed by TMPK to thymidine 5-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5-diphosphate [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: dTDP sodium. CAS No. 108322-12-9. Pack Sizes: 5 mg. Product ID: HY-131576A.
Thymidine-5'-triphosphoric acid = ttp
Thymidine-5'-triphosphoric acid = ttp. Uses: Designed for use in research and industrial production. Additional or Alternative Names: thymidine 5'-(tetrahydrogen triphosphate);[hydroxy-[hydroxy-[[3-hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)-oxolan-2-yl]methoxy]phosphoryl]oxy-phosphoryl]oxyphosphonic acid;Thymidine-5''-triphosphoric acid;2'-Deoxythymidine triposphate;5-Methyl-dUTP;5'. Product Category: Heterocyclic Organic Compound. CAS No. 365-08-2. Molecular formula: C10H17N2O14P3. Mole weight: 482.166. Density: 1.922g/cm³. Product ID: ACM365082. Alfa Chemistry ISO 9001:2015 Certified. Categories: thymidine 5'-triphosphate.
Thymidine 5'-(trisodium hydrogen triphosphate)
Thymidine 5'-(trisodium hydrogen triphosphate). Uses: Designed for use in research and industrial production. Additional or Alternative Names: thymidine 5'-(trisodium hydrogen triphosphate);Thymidine-5'-Triphosphoric Acid Trisodium Salt;TTP-Na3;Thymidine-5'-TriphosphateTetrasodium;Thymidine 5'-(tetrahydrogen triphosphate) trisodium salt. Product Category: Heterocyclic Organic Compound. CAS No. 27821-54-1. Molecular formula: C10H13N2Na4O14P3. Mole weight: 570.095583. Product ID: ACM27821541. Alfa Chemistry ISO 9001:2015 Certified. Categories: EINECS 248-679-4.
3`-Deoxy-thymidine 5`-(Tetrahydrogen Triphosphate) is a component of a kit which is used for for genotyping detection of hepatitis B virus by single base extension and detection. Group: Biochemicals. Grades: Highly Purified. CAS No. 611-60-9. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C10H17N2O13P3, Molecular Weight: 466.17. US Biological Life Sciences.
5-[2-[(6-Aminohexyl)amino]-2-oxoethyl]-2'-deoxyuridine 5'-(Tetrahydrogen Triphosphate) is a chemically modified nucleotide that can be used in polymerase chain reaction of DNA. Synonyms: alpha-(6-Aminohexylcarbamoyl)thymidine 5'-triphosphoric acid; [[(2R,3S,5R)-5-[5-[2-(6-aminohexylamino)-2-oxoethyl]-2,4-dioxopyrimidin-1-yl]-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate. CAS No. 402789-71-3. Molecular formula: C17H31N4O15P3. Mole weight: 624.37.
Acyclovir (Zovirax, Acycloguanosine)
Acyclovir (Zovirax) is classified as an antiviral used in the treatment of Herpes genitalis, herpes simplex, herpes zoster and other diseases. Acyclovir inhibits the replication of viral DNA needed to reproduce itself. Phosphorylation by herpes simplex virus thymidine kinase (HSV-TK) leads to the formation of acycloguanosine triphosphate that competitively inhibits the viral DNA polymerase. Acycloguanosine can be used to induce apoptosis in cells transfected with HSV-TK. Inhibits replication of cytomegalovirus by a mechanism that is independent of its phosphorylation by viral or cellular thymidine kinase. Group: Biochemicals. Alternative Names: Acycloguanosine; 9-[ (2-Hydroxyethoxy) methyl]guanine. Grades: USP. CAS No. 59277-89-3. Pack Sizes: 1g, 10g, 100g. US Biological Life Sciences.
In the extracellular space, ecto-5?-nucleotidase (CD73) dephosphorylates adenosine triphosphate (ATP) to produce adenosine. Adenosine has four receptors namely A1R, A2AR A2BR and A3R. Adenosine plays a key role in the osteogenic differentiation. A1R induces osteoclast differentiation and A2AR induces osteoblast differentiation. Adenosine has been used: as a supplement in embryonic type culture medium for in vitro osteogenic differentiation for evaluation of its effect on cell survival by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT assay) and cell proliferation by 3H-thymidine incorporation assay in multi drug resistant glioblastoma stem-like cells (GSCs), and as a standard in high performance liquid chromatography (HPLC). as a constituent in collagenase solution for the collagenase digestion of mice fat tissue. Group: Biochemicals. Alternative Names: 9- β-D-Ribofuranosyl-9H-purin-6-amine; 9- β-D-Ribofuranosyladenine; Adenine Riboside; Adenocard; Adenocor; Adenogesic; Adenoscan; Adrekar; Boniton; D-Adenosine; 1-(6-Amino-9H-purin-9-yl)-1-deoxy- β-D-ribofuranose; Myocol; NSC 7652. Grades: Molecular Biology Grade. CAS No. 58-61-7. Pack Sizes: 100g, 500g. Molecular Formula: C10H13N5O4, Molecular Weight: 267.25. US Biological Life Sciences.
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ANX-510
ANX-510 is a folate-based biomodulator with potential antineoplastic activity. 5,10-methylenetetrahydrofolate (MTHF) stabilizes the covalent binding of the fluorouracil metabolite 5-5-fluoro-2'-deoxyuridine-5'-O-monophosphate (FdUMP) to its target enzyme, thymidylate synthase, which results in inhibition of thymidylate synthase, depletion of thymidine triphosphate (TTP), a necessary constituent of DNA, and tumor cell death. Synonyms: 5,10-Methylenetetrahydrofolic acid; 5,10-Methylene-tetrahydrofolate; Tetrahydromethylenefolate; N-{4-[3-amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl}-L-glutamic acid. CAS No. 3432-99-3. Molecular formula: C20H23N7O6. Mole weight: 457.44.
Azidothymidine (3'-Azido-3'-deoxythymidine, AZT, Zidovudine)
Azidothymidine is a nucleoside reverse transcriptase inhibitor that, following triphosphorylation by thymidine kinase, potently blocks replication of HIV (EC?? = 3nM) with low cytotoxicity (CC?? >5uM). Displays 100-fold selectivity for HIV reverse transcriptase over DNA polymerase α. Suppresses HIV-1 replication and enhances cell viability in HIV-1 infected T cells. Antiretroviral agent. Also decreases CRISPR-mediated homology directed repair (HDR) efficiency. Group: Biochemicals. Alternative Names: AZT; Zidovudine; Azidothymidine; 3'-Azido-3'-deoxythymidine; Retrovis; Timazid; Retrovir; NSC 602670. Grades: Highly Purified. CAS No. 30516-87-1. Pack Sizes: 100mg, 250mg, 500mg, 1g, 5g. Molecular Formula: C10H13N5O4, Molecular Weight: 267.24. US Biological Life Sciences.
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Fazarabine
Fazarabine, also known as Kymarabine, is an orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is phosphorylated by deoxycytidine kinase to a triphosphate form which competes with thymidine for incorporation into DNA; its incorporation into DNA inhibits DNA synthesis, resulting in tumor cell death and tumor necrosis. The presence of deoxycytidine kinase in a tumor is a determinant of tumor sensitivity to this drug. Synonyms: CCRIS 93; CCRIS-93; CCRIS93; NSC 281272; NSC-281272; NSC281272; Ara-AC; 5-Azacytosine arabinoside; 1-beta-D-Arabinofuranosyl-5-azacytosine. CAS No. 65886-71-7. Molecular formula: C8H12N4O5. Mole weight: 244.20.
Stavudine sodium
Stavudine sodium is a dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. Stavudine sodium is an analog of thymidine. It is phosphorylated by cellular kinases into active triphosphate. Stavudine sodium triphosphate inhibits the HIV reverse transcriptase by competing with natural substrate, thymidine triphosphate. It also causes termination of DNA synthesis by incorporating into it. Mice were treated for 2 weeks with stavudine d4T (500 mg/kg/day), L-carnitine (200 mg/kg/day) or both drugs concomitantly. Body fatness was assessed by dual energy X-ray absorptiometry, and investigations were performed in plasma, liver, muscle and WAT. D4T reduced the gain of body adiposity, WAT leptin, whole body FAO and plasma ketone bodies, and increased liver triglycerides and plasma aminotransferases with mild ultrastructural abnormalities in hepatocytes. Synonyms: Zerit sodium; d4T sodium. Grades: >98%. CAS No. 134624-73-0. Molecular formula: C10H11N2NaO4. Mole weight: 246.2.
Stavudine Triphosphate TEA Salt
Stavudine Triphosphate TEA Salt. Group: Biochemicals. Alternative Names: 5'-(Tetrahydrogen triphosphate), 2',3'-didehydro-3'-deoxy-thymidine N,N-Diethylethanamine Triethylamine Salt. Grades: Highly Purified. CAS No. 117404-75-8. Pack Sizes: 5mg. Molecular Formula: C16H30N3O13P3, Molecular Weight: 565.34. US Biological Life Sciences.
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Thymidine 5'-Diphosphate Sodium Salt
Thymidine 5'-Diphosphate Sodium Salt is a nucleoside diphosphate derived from phosphorylation of Thymidine. Which is produced from Thymidine monophosphate by Thymidylate kinase (TMPK), that is a nucleoside monophosphate kinase and can be futher phosphorylated to its active triphosphate antiviral or antitumor moieties. A proximate precursor for DNA synthesis. Synonyms: Thymidine 5'-(Trihydrogen Diphosphate) Sodium Salt. Grades: 90%. CAS No. 108322-12-9. Molecular formula: C10H16N2O11P2 xNa. Mole weight: 402.19.
Valacyclovir is a prodrug of Acyclovir with inhibitory activity against herpes simplex virus types 1 (HSV-1), 2 (HSV-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), and cytomegalovirus (CMV). Valacyclovir is phosphorylated by viral thymidine kinase to acyclovir triphosphate (the active metabolite) which then inhibits herpes viral DNA replication by competitive inhibition of viral DNA polymerase, and by incorporation into and termination of the growing viral DNA chain. Group: Biochemicals. Grades: Highly Purified. CAS No. 124832-27-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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