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2',3'-Didehydro-3'-deoxy-thymidine-5'-monophosphate, lithium salt
2',3'-Didehydro-3'-deoxy-thymidine-5'-monophosphate, lithium salt is an indispensable biomedical compound, renowned for its potent antiviral properties against DNA viruses like herpes simplex virus. By meticulously impeding viral DNA synthesis, this nucleoside analogue exhibits unparalleled efficacy in curbing viral replication and thwarting their insidious spread. This remarkable product finds profound utility in the realm of biomedicine, facilitating cutting-edge research endeavors and propelling breakthroughs in pharmacotherapeutic advances. Molecular formula: C10H11Li2N2O7P. Mole weight: 316.06.
3'-Azido-3'-deoxythymidine-5'-monophosphate lithium salt
3'-Azido-3'-deoxythymidine-5'-monophosphate lithium salt, an extraordinary antiviral pharmaceutical compound employed in the treatment of HIV/AIDS, showcases its potency by impeding the reverse transcriptase enzyme, an essential player in viral replication. With its roots in thymidine, this lithium salt not only bestows augmented cellular penetration but also amplifies antiviral efficacy against HIV. Molecular formula: C10H14N5O7P·xLi. Mole weight: 347.22 (free acid).
3'-Azido-3'-deoxythymidine 5'-monophosphate sodium salt
3'-Azido-3'-deoxythymidine 5'-monophosphate sodium salt is an indispensable element in the realm of biomedicine. It assumes a pivotal role as a significant intermediary during the production of antiviral medications, including Zidovudine (AZT). This compound emerges as a potent inhibitor of reverse transcriptase, thereby effectively combatting the relentless progression of HIV and AIDS. Synonyms: Zidovudine 5'-monophosphate sodium salt; AzTMP; 3'-Azido-3'-deoxy-D-thymidine 5'-monophosphate sodium salt. Grade: 97%. CAS No. 128506-29-6. Molecular formula: C10H13N5NaO7P. Mole weight: 369.23.
3'-Deoxy-3'-fluorothymidine-5'-monophosphate-d3 Disodium Salt
3-Deoxy-3-fluorothymidine-5-monophosphate-d3 Disodium Salt
A thymidine-5'-O-monophosphate analogue as inhibitors of Mycobacterium tuberculosis thymidylate kinase. Group: Biochemicals. Alternative Names: 3'-Deoxy-3'-fluoro-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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3'-Deoxy-3'-fluorothymidine-5'-monophosphate Disodium Salt
A thymidine-5'-O-monophosphate analogue as inhibitors of Mycobacterium tuberculosis thymidylate kinase. Synonyms: 3'-Deoxy-3'-fluoro-5'-thymidylic Acid Disodium; 2',3'-Dideoxy-3'-fluoro-5-methyluridine 5'-(Dihydrogen Phosphate) Disodium; 3'-Deoxy-3'-fluorothymidine Monophosphate Disodium; 3'-Fluoro-3'-deoxythymidine Monophosphate Disodium. Grade: 95%. CAS No. 1316845-74-5. Molecular formula: C10H12FN2Na2O7P. Mole weight: 368.16.
3-Deoxy-3-fluorothymidine-5-monophosphate Disodium Salt
A thymidine-5'-O-monophosphate analogue as inhibitors of Mycobacterium tuberculosis thymidylate kinase. Group: Biochemicals. Alternative Names: 3'-Deoxy-3'-fluoro-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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L-Thymidine-5'-monophosphate sodium salt
L-Thymidine-5'-monophosphate sodium salt. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.
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Thymidine-13C10, 15N2 5?-monophosphate disodium salt
?98 atom %, ?95% (CP). Group: Fluorescence/luminescence spectroscopy.
Thymidine-13C10,15N2 5?-monophosphate sodium salt solution
?98 atom %, ?95% (CP), 100 mM in 5 mM Tris HCl. Group: Fluorescence/luminescence spectroscopy.
Thymidine-5'-monophosphate (disodium) salt
Thymidine-5'-monophosphate disodium salt is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 33430-62-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-128738.
Thymidine-5'-monophosphate disodium salt
Thymidine-5'-monophosphate disodium salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 33430-62-5. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C10H13N2Na2O8P. US Biological Life Sciences.
Worldwide
Thymidine 5'-monophosphate disodium salt (dTMP)
1g Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Diagnostic Raw Materials. Formula: C10H13N2Na2O8P. CAS No. 33430-62-5. Prepack ID 67878505-1g. Molecular Weight 366.17. See USA prepack pricing.
It is a potential inhibitor of mycobacterium tuberculosis monophosphate kinase (TMPKmt). Synonyms: 5'-AZT; 5'-Azido-5'-deoxythymidine; NSC 254064; 5'-N3-5-Me-ddU; 5'-Azido-5-methyl-2',5'-dideoxyuridine; 1-((2R,4S,5R)-5-(azidomethyl)-4-hydroxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione. Grade: ≥95%. CAS No. 19316-85-9. Molecular formula: C10H13N5O4. Mole weight: 267.24.
5'-O-Trityl-3'-β-hydroxythymidine-d3
It can be used as an intermediate in the preparation of labelled thymidine monophosphate analogues. Synonyms: 1-[2-Deoxy-5-O-(triphenylmethyl)-β-D-threo-pentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione-d3; 1-(2-Deoxy-5-O-trityl-β-D-threo-pentofuranosyl)thymine-d3. Molecular formula: C29H25D3N2O5. Mole weight: 487.56.
5-O-Trityl-3- β-hydroxythymidine-d3
An intermediate in the preparation of labeled thymidine monophosphate analogues. Group: Biochemicals. Alternative Names: 1-[2-Deoxy-5-O-(triphenylmethyl)- β-D-threo-pentofuranosyl]-5-methyl-. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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5-O-Trityl-3'-deoxy-3'-fluorothymidine
An intermediate in the synthesis of thymidine monophosphate analogues. Uses: An intermediate in the preparation of thymidine monophosphate analogues. Synonyms: 3'-Deoxy-3'-fluoro-5'-O-(triphenylmethyl)thymidine. Grade: 95%. CAS No. 135197-63-6. Molecular formula: C29H27FN2O4. Mole weight: 486.53.
5-O-Trityl-3'-deoxy-3'-fluorothymidine-d3
An intermediate in the synthesis of labelled thymidine monophosphate analogues. Synonyms: 3'-Deoxy-3'-fluoro-5'-O-(triphenylmethyl)thymidine-d3. Molecular formula: C29H24D3FN2O4. Mole weight: 489.55.
5-O-Trityl-3-deoxy-3-fluorothymidine-d3
An intermediate in the preparation of labeled thymidine monophosphate analogues. Group: Biochemicals. Alternative Names: 3'-Deoxy-3'-fluoro-5'-O- (triphenylmethyl) thymidine-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
5'-Thymidylic acid, disodium salt
5'-Thymidylic acid, disodium salt is a paramount biomedical compound, playing the role of a nucleotide analog. It exerts its inhibitory prowess on viral DNA replication, thereby impeding the rampant multiplication of the virus. Synonyms: Thymidine-5'-monophosphate disodium salt; sodium ((2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl phosphate. Grade: ≥97% by HPLC. CAS No. 33430-62-5. Molecular formula: C10H13N2Na2O8P. Mole weight: 366.17.
5'-TMPS
5'-TMPS is a potent, competitive inhibitor that regulates enzymes. It can interact with thymidine-5'-monophosphate. Synonyms: Thymidine- 5'- O- monophosphorothioate, sodium salt. Grade: ≥ 97% by HPLC. CAS No. 15548-51-3. Molecular formula: C10H15N2O7PS (free acid). Mole weight: 338.3 (free acid).
ANX-510
ANX-510 is a folate-based biomodulator with potential antineoplastic activity. 5,10-methylenetetrahydrofolate (MTHF) stabilizes the covalent binding of the fluorouracil metabolite 5-5-fluoro-2'-deoxyuridine-5'-O-monophosphate (FdUMP) to its target enzyme, thymidylate synthase, which results in inhibition of thymidylate synthase, depletion of thymidine triphosphate (TTP), a necessary constituent of DNA, and tumor cell death. Synonyms: 5,10-Methylenetetrahydrofolic acid; 5,10-Methylene-tetrahydrofolate; Tetrahydromethylenefolate; N-{4-[3-amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl}-L-glutamic acid. CAS No. 3432-99-3. Molecular formula: C20H23N7O6. Mole weight: 457.44.
Clevudine
Clevudine is an inhibitor of hepatitis B virus (HBV). It is metabolized in cells by the cellular thymidine kinase as well as deoxycytidine kinase to its monophosphate, and subsequently to the di- and triphosphate, which are biologically active. Uses: Antiviral agents. Synonyms: 1-(2'-Deoxy-2'-fluoro-β-L-arabinofuranosyl)-5-methyluracil; L-FMAU; 1-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; L FMAU; LFMAU; Levovir; 2'-Fluoro-5-methyl-b-L-arabinofuranosyluracil. Grade: ≥98% by HPLC. CAS No. 163252-36-6. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
cTMP
cTMP (2?,3?-dideoxy-3?-thiothymidine) is an exceptional biomedical compound ubiquitously applied in studying the pernicious Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS). Functioning as a high-potency antiretroviral compound, cTMP exercises its efficacious mechanism by adeptly obstructing the pernicious reverse transcriptase enzyme. Synonyms: Thymidine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. CAS No. 76567-90-3. Molecular formula: C10H12N2O7P · Na. Mole weight: 326.2.
dTMP kinase
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is ATP:dTMP phosphotransferase. Other names in common use include thymidine monophosphate kinase, thymidylate kinase, thymidylate monophosphate kinase, thymidylic acid kinase, thymidylic kinase, deoxythymidine 5'-monophosphate kinase, TMPK, and thymidine 5'-monophosphate kinase. This enzyme participates in pyrimidine metabolism. Group: Enzymes. Synonyms: thymidine monophosphate kinase; thymidylate kinase; thymidylate monophosphate kinase; thymidylic acid kinase; thymidylic kinase; deoxythymidine 5'-monophosphate kinase; TMPK; thymidine 5'-monophosphate kinase. Enzyme Commission Number: EC 2.7.4.9. CAS No. 9014-43-1. TMPK. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3219; dTMP kinase; EC 2.7.4.9; 9014-43-1; thymidine monophosphate kinase; thymidylate kinase; thymidylate monophosphate kinase; thymidylic acid kinase; thymidylic kinase; deoxythymidine 5'-monophosphate kinase; TMPK; thymidine 5'-monophosphate kinase. Cat No: EXWM-3219.
Phenyl Chlorothionoformate.
Phenyl Chlorothionoformate is used in the preparation of an bicyclic thymidine analogs as selective inhibitors of Thymidine monophosphate kinase Mycobacterium tuberculosis (TMPKmt). Group: Biochemicals. Alternative Names: Carbonochloridothioic Acid O-Phenyl Ester; Chlorothioformic Acid O-Phenyl Ester; NSC 99103; O-Phenyl Carbonochloridothioate ; O-Phenyl Chlorothiocarbonate; O-Phenyl Chlorothioformate; O-Phenyl Chlorothionoformate; Phenoxythiocarbonyl Chloride; Phenyl Chlorothiocarbonate; Phenyl Chlorothionoformate; Phenyl Thiochloroformate; Phenyl Thionochloroformate; Phenyl Thioxochloroformate. Grades: Highly Purified. CAS No. 1005-56-7. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Thymidine 5-diphosphate sodium
Thymidine 5-diphosphate (dTDP) sodium is the key product of pyrimidine synthesis in organisms. Thymidine 5-diphosphate sodium is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5-thymidine monophosphate (dTMP), which requires ATP and Mg 2+. Thymidine 5-diphosphate sodium is further catalyzed by TMPK to thymidine 5-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5-diphosphate [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: dTDP sodium. CAS No. 108322-12-9. Pack Sizes: 5 mg. Product ID: HY-131576A.
thymidylate synthase
Thymidylate synthetase (EC 2.1.1.45) is an enzyme that catalyzes the conversion of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP). Thymidine is one of the nucleotides in DNA. With inhibition of TS, an imbalance of deoxynucleotides and increased levels of dUMP arise. Both cause DNA damage. Group: Enzymes. Synonyms: dTMP synthase; thymidylate synthetase; methylenetetrahydrofolate:dUMP C-methyltransferase; TMP synthetase. Enzyme Commission Number: EC 2.1.1.45. CAS No. 9031-61-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1949; thymidylate synthase; EC 2.1.1.45; 9031-61-2; dTMP synthase; thymidylate synthetase; methylenetetrahydrofolate:dUMP C-methyltransferase; TMP synthetase. Cat No: EXWM-1949.
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