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2- (2-Hydroxy-2- (4- (4-hydroxy-3, 5-diiodophenoxy) -3, 5-diiodophenyl) acetamido) -3- (4- (4-hydroxy-3, 5-diiodophenoxy) -3, 5-diiodophenyl) propanoic Acid, Amide-Bridged is a Levothyroxine impurity of Thyroxine (T425600), which is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Thyroxine is deiodinated in peripheral tissues to the active metabolite, liothyronine, which has been used to treat hyperlipidemia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C29H17I8NO8, Molecular Weight: 1522.68. US Biological Life Sciences.
2-(3-(4-Hydroxy-3,5-diiodophenoxy)-2,4-diiodobenzamido)-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoic Acid, Amide-Bridged is a Levothyroxine impurity of Thyroxine (T425600), which is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Thyroxine is deiodinated in peripheral tissues to the active metabolite, liothyronine, which has been used to treat hyperlipidemia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C28H16I7NO7, Molecular Weight: 1366.76. US Biological Life Sciences.
(2S)-2-Amino-3-(4-(4-(2-hydroxy-2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetoxy)-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic Acid, Ester-Bridged is a Levothyroxine impurity of Thyroxine (T425600), which is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Thyroxine is deiodinated in peripheral tissues to the active metabolite, liothyronine, which has been used to treat hyperlipidemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 2088032-74-8. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C29H17I8NO8, Molecular Weight: 1522.68. US Biological Life Sciences.
(2S,2'S)-3,3'-(((6,6'-Dihydroxy-5,5'-diiodo-[1,1'-biphenyl]-3,3'-diyl)bis(oxy))bis(3,5-diiodo-4,1-phenylene))bis(2-aminopropanoic acid) is a Levothyroxine impurity of Thyroxine (T425600), which is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Thyroxine is deiodinated in peripheral tissues to the active metabolite, liothyronine, which has been used to treat hyperlipidemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 2088032-54-4. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C30H22I6N2O8, Molecular Weight: 1299.93. US Biological Life Sciences.
(2S,2'S)-3,3'-(((6,6'-Dihydroxy-5-iodo-[1,1'-biphenyl]-3,3'-diyl)bis(oxy))bis(3,5-diiodo-4,1-phenylene))bis(2-aminopropanoic Acid) is a Levothyroxine impurity of Thyroxine (T425600), which is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Thyroxine is deiodinated in peripheral tissues to the active metabolite, liothyronine, which has been used to treat hyperlipidemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 2088032-60-2. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C30H23I5N2O8, Molecular Weight: 1174.03. US Biological Life Sciences.
Worldwide
3,3',5,5'-Tetraiodo-L-thyronine sodium salt
3,3',5,5'-Tetraiodo-L-thyronine sodium saltm is the sodium salt of levothyroxine, a synthetic levoisomer of thyroxine (T4) that is similar to the endogenous hormone produced by the thyroid gland. In peripheral tissues, levothyroxine is deiodinated by 5'-deiodinase to form triiodothyronine (T3). T3 enters the cell and binds to nuclear thyroid hormone receptors, the activated hormone-receptor complex in turn triggers gene expression and produces proteins required in the regulation of cellular respiration, thermogenesis, cellular growth and differentiation, and the metabolism of proteins, carbohydrates and lipids. T3 also exhibits cardiostimulatory effects. Synonyms: L-Thyroxine NaLevothyroxine sodium; Levothyroxine sodium; L-Thyroxine sodium; Euthyrox; Unithroid; Levoxyl; eltroxin; Novothyrox; Levaxin; Letter; levothroid; Sodium levothyroxine; Sodium thyroxinate; L-Thyroxine sodium salt; Sodium L-thyroxine; synthroid; Laevoxin; Thyroxevan; Oroxine; Thyroxin sodium; sodium;(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate. Grades: ≥ 98% (HPLC). CAS No. 25416-65-3. Molecular formula: C15H10I4NNaO4. Mole weight: 798.85.
3,5-Diiodo-4-hydroxy-DL-phenyllactic Acid
3,5-Diiodo-4-hydroxy-DL-phenyllactic Acid is an intermediate in synthesizing 3,5,3',5'-Tetraiodo Thyrolactic Acid (T296160), a thyroid hormone analogue. A Thyroxine (T425600) analogue. Group: Biochemicals. Grades: Highly Purified. CAS No. 15220-05-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C9H8I2O4. US Biological Life Sciences.
3,5-Diiodo-4-O-methyl Thyroacetic Acid Ethyl Ester is a derivative of 3,5-Diiodo Thyroacetic Acid (D455140), the acetic acid analog of Thyroxine (T425601). It is a reactant in the preparation of bifunctional thyrointegrin inhibitors, thyroxine (T425601) and triiodothyronine (T795380). Group: Biochemicals. Alternative Names: 3,5-Diiodo-4-(4-methoxyphenoxy)-benzeneacetic Acid Ethyl Ester; [3,5-Diiodo-4-(p-methoxyphenoxy)phenyl]-acetic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 85828-82-6. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Boc-L-thyroxine
Boc-T4 is a synthetic prodrug of thyroxine, a hormone produced by the thyroid gland that plays a crucial role in regulating metabolism and other physiological processes. Boc-T4 is designed to be a prodrug that can be activated by enzymes in the body to release thyroxine slowly over a prolonged period. This approach can reduce the dosage frequency and provide a more sustained release of the hormone. Uses: Boc-t4 has potential applications in various fields of research and industry, including drug development, biomedical research, and agriculture. the compound can be used as a prodrug for thyroxine, providing a more sustained release of the hormone and reducing the dosage frequency. boc-t4 can also serve as a tool for studying the role of thyroxine in various physiological processes. Group: Amino acids. Alternative Names: N-(tert-Butyloxy)carbonyl-L-thyroxine, Boc-T4. CAS No. 88404-22-2. Molecular formula: C20H19I4NO6. Mole weight: 877. Purity: Peak Area by HPLC ≥95%. IUPACName: (2S)-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid. Canonical SMILES: CC (C) (C)OC (=O)N[C@@H] (CC1=CC (=C (C (=C1)I)OC2=CC (=C (C (=C2)I)O)I)I)C (=O)O. Catalog: ACM88404222.
D-Thyroxine
D-Thyroxine (D-T4) is an orally active thyroid hormone that inhibits the secretion of TSH. D-Thyroxine can inhibit goiter, promote metamorphosis of tadpoles and influence cholesterol metabolism. D-Thyroxine can be used for the study of hypercholesterolemia [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: D-T4. CAS No. 51-49-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-A0152.
D-Thyroxine
D-Thyroxine is the dextrorotary isomer of thyroxine with antihyperlipidemic activity. It stimulates the formation of low-density lipoprotein (LDL) and increases the catabolism of LDL thereby leading to increased excretion of cholesterol and bile acids via the biliary route. It is released from thyroglobulin by proteolysis and secreted into the blood. It is one of the thyroid hormones involved in the maintenance of metabolic homeostasis and has been used to treat hyperlipidemia. It is used as an cholesterol-lowering drug but was pulled due to cardiac side-effects. It also increases hepatic lipase which in turn improves utilization of triglycerides, improving apolipoprotein E cholesterol particles. Uses: D-thyroxin is one of the thyroid hormones involved in the maintenance of metabolic homeostasis and has been used to treat hyperlipidemia. it is used as an cholesterol-lowering drug. Synonyms: Dextrothyroxine; Choloxin; Dextrothyroxinum; (R)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid; Biotirmone; Debetrol; D-T4; O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-D-tyrosine. Grades: 95%. CAS No. 51-49-0. Molecular formula: C15H11I4NO4. Mole weight: 776.87.
Liothyronine Impurity E
An impurity of Liothyronine which is a man-made form of thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Synonyms: diiodothyronine; O-(4-HYDROXYPHENYL)-3,5-DIIODO-L-TYROSINE; 3,5-DIIODO-L-THYRONINE; 3,5-DIIODO-4-(4-HYDROXYPHENOXY)-L-PHENYLALANINE; L-TYROSINE, O-(4-HYDROXYPHENYL)-3,5-DIIODO-; 3-5-diiodo-L-thyronine crystalline; 3,5-diiodothyronine. Grades: > 95%. CAS No. 1041-01-6. Molecular formula: C15H13I2NO4. Mole weight: 525.08.
L-Thyroxine
L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Levothyroxine; T4. CAS No. 51-48-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-18341.
L-Thyroxine-13C6
L-Thyroxine- 13 C 6 is the 13 C labeled L-Thyroxine[1]. L-Thyroxine (Levothyroxine;T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4)[2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 720710-30-5. Pack Sizes: 100 μg. Product ID: HY-18341S2.
L-Thyroxine sodium
L-Thyroxine sodium (Levothyroxine sodium) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Levothyroxine sodium; T4 sodium. CAS No. 55-03-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-18341B.
L-Thyroxine sodium salt pentahydrate
L-Thyroxine sodium salt pentahydrate is an iodine containing hormone produced from thyroglobulin in the thyroid follicular cells. It reduces total cholesterol level, low-density lipoprotein cholesterol as well as waist to hip ratio in subclinical hypothyroidism pateints. It was also used to study the light-induced hormone conversion of T4 to T3 in regulation of photoperiodic response of gonads in Japanese quail. Synonyms: Sodium levothyroxine pentahydrate. Grades: >98%. CAS No. 6106-7-6. Molecular formula: C15H20I4NNaO9. Mole weight: 888.93.
N-(Trifluoroacetyl)-L-thyroxine Methyl Ester
N-(Trifluoroacetyl)-L-thyroxine Methyl Ester is a Thyroxine (T425600) derivative used in the preparation of Thyroxine 4-O- β-D-Glucuronide (T425630). Group: Biochemicals. Grades: Highly Purified. CAS No. 906325-95-9. Pack Sizes: 25mg. US Biological Life Sciences.
N-(Trifluoroacetyl)-thyroxine 2,3,4-O-Triacetyl-4-O- β-D-glucuronide Dimethyl Diester is an intermediate in the preparation of Thyroxine 4-O- β-D-Glucuronide (T425630), a major metabolite Thyroxine (T425600). Group: Biochemicals. Alternative Names: 4-[4-[(2S)-2-(Trifluoroacetamide)-2-carboxyethyl]-2,6-diiodophenoxy]-2,6-diiodophenyl 2,3,4-O-Triacetyl- β-D-glucopyranosiduronic Acid Dimethyl Diester. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Octinoxate
Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Octyl methoxycinnamate. CAS No. 5466-77-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1234.
O-Methyl Tetraiodothyroethylamine
An impurity of Thyroxine which is formed by the molecular addition of iodine to the amino acid tyrosine while the latter is bound to the protein thyroglobulin. Synonyms: O-methyl-tetraiodothyroethylamine; T4-AMINE O-METHYL; X6P4742Z19; Q27293608; 2-(4-(3,5-DIIODO-4-METHOXYPHENOXY)-3,5-DIIODOPHENYL)ETHANAMINE; LEVOTHYROXINE SODIUM IMPURITY, O-METHYL-TETRAIODOTHYROETHYLAMINE, OR T4-AMINE O-METHYL- [USP IMPURITY]. Grades: > 95%. Molecular formula: C15H13I4NO2. Mole weight: 746.89.
Thyroglobulin
Thyroglobulin is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Thyroglobulin acts as a substrate for the synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), as well as the storage of the inactive forms of thyroid hormone and iodine within the follicular lumen of a thyroid follicle [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Thyroglobulin from bovine. CAS No. 9010-34-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107903.
Thyroxine sulfate
Thyroxine sulfate is a thyroid hormone metabolite. Uses: Scientific research. Group: Natural products. Alternative Names: T4 Sulfate. CAS No. 77074-49-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101406.
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