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| Product | Description | |
|---|---|---|
| Tinostamustine | Tinostamustine (EDO-S101) is a pan HDAC inhibitor; inhibits HDAC6 , HDAC1 , HDAC2 and HDAC3 with IC 50 values of 6 nM, 9 nM, 9 nM and 25 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EDO-S101; NL-101. CAS No. 1236199-60-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101780. |  |
| Tinostamustine (EDO-S101) | Tinostamustine (EDO-S101). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1236199-60-2. Molecular formula: C19H28Cl2N4O2. Mole weight: 415.36. Catalog: APB1236199602. |  |
| Tinostamustine Hydrochloride | The hydrochloride salt form of Tinostamustine, a benzimidazol derivative, has been found to be a HDAC inhibitor and could probably be effective against sorts of cancers like haematological malignancies and solid tumours. And it is still under Phase-I trial against solid tumours. Synonyms: EDO-S101; EDO-S 101; EDO-S-101; EDO-S101 HCl; EDO-S101 hydrochloride; Tinostamustine hydrochloride; 7-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)-N-hydroxyheptanamide hydrochloride. Grades: 98%. CAS No. 1793059-58-1. Molecular formula: C19H29Cl3N4O2. Mole weight: 451.82. |  |
| EDO-S101 | EDO-S101 is a pan HDAC inhibitor (IC50 = 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3, respectively). EDO-S101 is a first-in-class fusion molecule that combines DNA damaging effect of bendamustine with the pan-HDACi vorinostat. Synonyms: 7-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]-N-hydroxyheptanamide; EDO-S101; EDO-S 101; EDO-S-101; EDO-S101 HCl; EDO-S101 hydrochloride; Tinostamustine hydrochloride. CAS No. 1236199-60-2. Molecular formula: C19H28Cl2N4O2. Mole weight: 415.36. | |
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