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Tizoxanide A metabolite of Nitazoxonide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. USBiological 1
Worldwide
Tizoxanide Tizoxanide is the active metabolite of nitazoxanide, an anti-infective that has been approved for the treatment of diarrhea caused by Giardia lamblia or Crytosporidium parvum. Tizoxanide is active against anaerobic bacteria, protozoan parasites, and viruses. It reduces the growth of the disease-causing parasites, L. mexicana and T. cruzi, in vitro (IC50s = 6.2 and 17.5 μM, respectively), inhibits influenza A replication (EC50s = 0.3-1 μM)3, and inhibits hepatitis B and hepatitis C virus replication (EC50s both=0.15 μM). Uses: Anti-infective agents. Synonyms: TIZ; NSC-697856; NSC697856; NSC697856; Tizoxanide; Desacetylnitazoxanide; Desacetyl-nitazoxanide. Grades: >98%. CAS No. 173903-47-4. Molecular formula: C10H7N3O4S. Mole weight: 265.25. BOC Sciences 8
Tizoxanide Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has anti-HIV-1 activities and potent inhibition of both HBV and HCV replication with values EC 50 of 0.46μM and 0.15 μM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-κB and the MAPK signaling pathways in LPS-treated macrophage cells [1] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TIZ. CAS No. 173903-47-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12687. MedChemExpress MCE
Tizoxanide Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has anti-HIV-1 activities and potent inhibition of both HBV and HCV replication with values EC50 of 0.46μM and 0.15 μM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-κB and the MAPK signaling pathways in LPS-treated macrophage cells. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 173903-47-4. Molecular formula: C10H7N3O4S. Mole weight: 265.243. Purity: 0.97. Canonical SMILES: O=C(NC1=NC=C([N+]([O-])=O)S1)C2=CC=CC=C2O. Product ID: ACM173903474. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Tizoxanide Glucuronide Sodium Salt One of the metabolite impurities of Nitazoxanide, which is a hepatitis B as well as hepatitis C virus inhibitor and could exhibit potential effect in studies of tuberculosis. Synonyms: 2-[[(5-Nitro-2-thiazolyl)amino]carbonyl]phenyl β-D-Glucopyranosiduronic Acid Monosodium Salt. CAS No. 221287-83-8. Molecular formula: C16H14N3NaO10S. Mole weight: 463.35. BOC Sciences 11
Tizoxanide sulfate One of the metabolite impurities of Nitazoxanide, which is a hepatitis B as well as hepatitis C virus inhibitor and could exhibit potential effect in studies of tuberculosis. Synonyms: 2-Sulfooxy-N-(5-nitro-2-thiazolyl)benzamide. CAS No. 1391053-06-7. Molecular formula: C10H7N3O7S2. Mole weight: 345.31. BOC Sciences 7

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