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| Product | Description | |
|---|---|---|
| Tolcapone | Tolcapone (Ro 40-7592) is a selective, orally active and powerful mixed (peripheral and central) COMT inhibitor with an IC 50 of 773?nM in the liver [1]. Tolcapone is also a potent inhibitor of α-syn and Aβ42 oligomerization and fibrillogenesis [2]. Tolcapone induces oxidative stress leading to apoptosis and inhibition of tumor growth in neuroblastoma [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 40-7592. CAS No. 134308-13-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17406. |  |
| Tolcapone ( (3, 4-Dihydroxy-5-nitro-phenyl) (4-methylphenyl) methanone, Ro-40-7592, Tasmar) | Orally active inhibitor of central and peripheral catechol-O-methyltransferase (COMT). Antiparkinsonian. Group: Biochemicals. Alternative Names: (3, 4-Dihydroxy-5-nitro-phenyl) (4-methylphenyl) methanone; Ro-40-7592; Tasmar. Grades: Highly Purified. CAS No. 134308-13-7. Pack Sizes: 100mg. US Biological Life Sciences. |  Worldwide |
| Tolcapone-d4 | Orally active inhibitor of central and peripheral catechol-O-methyltransferase (COMT). Antiparkinsonian. Group: Biochemicals. Alternative Names: (3,4-Dihydroxy-5-nitrophenyl)(4-methylphenyl-d4)methanone; Ro-40-7592-d4; Tasmar-d4. Grades: Highly Purified. CAS No. 1246816-93-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Tolcapone-[d4] | Tolcapone-[d4] is the labelled analogue of Tolcapone. Tolcapone is a nitrocatechol-type inhibitor of the enzyme catechol-O-methyltransferase. It can be used to treat Parkinson's disease. Synonyms: Tolcapone D4; (3,4-Dihydroxy-5-nitrophenyl)(4-methylphenyl-d4)methanone. Grade: 95% by HPLC; 98% atom D. CAS No. 1246816-93-2. Molecular formula: C14H7D4NO5. Mole weight: 277.27. |  |
| Tolcapone-[d7] | An isotope labelled form of Tolcapone. Tolcapone is a nitrocatechol-type inhibitor of the enzyme catechol-O-methyltransferase. It can be used to treat Parkinson's disease. Synonyms: Tolcapone-d7; 5-[4-(D3)methyl(D4)benzoyl]-3-nitrobenzene-1,2-diol. Grade: 95% by HPLC; 98% atom D. CAS No. 2749285-04-7. Molecular formula: C14H4D7NO5. Mole weight: 280.28. | |
| Tolcapone Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. |  |
| Tolcapone Related Compound B | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| 3-O-Benzyl-4-O-methyl Tolcapone-d4 | 3-O-Methyl Tolcapone derivative. A metabolite of catechol-O-Methyl transferase inhibitor Tolcapone. Group: Biochemicals. Alternative Names: (3-Benzyloxy-4-methoxy-5-nitrophenyl)(4-methylphenyl)methanone-d4; 3-Benzyloxy-4-methoxy-4'-methyl-5-nitrobenzophenone-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 3-O-Methyl tolcapone | 3-O-Methyl tolcapone. Group: Biochemicals. Alternative Names: (4-Hydroxy-3-methoxy-5-nitrophenyl) (4-methylphenyl) methanone; 4-Hydroxy-3-methoxy-4'-methyl-5-nitrobenzophenone; Ro 40-7591. Grades: Highly Purified. CAS No. 134612-80-9. Pack Sizes: 25mg, 50mg. Molecular Formula: C15H13NO5. US Biological Life Sciences. | Worldwide |
| 3-O-Methyl Tolcapone | One of the impurities of Tolcapone, which is a COMT inhibitor and has been found to be active in antiparkinsonian studies. Synonyms: 4-Hydroxy-3-methoxy-4'-methyl-5-nitrobenzophenone; (4-Hydroxy-3-methoxy-5-nitrophenyl)(4-methylphenyl)methanone. CAS No. 134612-80-9. Molecular formula: C15H13NO5. Mole weight: 287.27. | |
| 3-O-Methyl Tolcapone-d4 | 3-O-Methyl Tolcapone-d4. Group: Biochemicals. Alternative Names: (4-Hydroxy-3-methoxy-5-nitrophenyl)(4-methylphenyl)methanone-d4; 4-Hydroxy-3-methoxy-4'-methyl-5-nitrobenzophenone-d4; Ro 40-7591-d4. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C15H9D4NO5, Molecular Weight: 291.29. US Biological Life Sciences. | Worldwide |
| 3-O-Methyl Tolcapone-d4 | One of the isotopic labelled impurities of Tolcapone, which is a COMT inhibitor and has been found to be active in antiparkinsonian studies. Synonyms: (4-Hydroxy-3-methoxy-5-nitrophenyl)(4-methylphenyl)methanone-d4; 4-Hydroxy-3-methoxy-4'-methyl-5-nitrobenzophenone-d4. Molecular formula: C15H9D4NO5. Mole weight: 291.29. | |
| 3-O-Methyltolcapone-[d7] | 3-O-Methyltolcapone-[d7] is the labelled analogue of 3-O-Methyl Tolcapone. 3-O-Methyl Tolcapone is one of the impurities of Tolcapone, which is a COMT inhibitor and has been found to be active in antiparkinsonian studies. Synonyms: Ro 40-7591 D7. Grade: > 95%. Molecular formula: C15H6D7NO5. Mole weight: 294.31. | |
| 3-Benzyloxy-4-methoxy-4'-methylbenzophenone | Intermediate in the preparation of Tolcapone and its derivatives. Group: Biochemicals. Alternative Names: (3-Benzyloxy-4-methoxyphenyl)(4-methylphenyl)-methanone. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 3-Benzyloxy-4-methoxy-4'-methylbenzophenone-d4 | Intermediate in the preparation of Tolcapone and its derivatives. Group: Biochemicals. Alternative Names: (3-Benzyloxy-4-methoxyphenyl)(4-methylphenyl)-methanone-d4. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 4-Hydroxy-3-methoxy-4'-methylbenzophenone | Intermediate in the preparation of Tolcapone and its derivatives. Group: Biochemicals. Alternative Names: (4-Hydroxy-3-methoxyphenyl)(4-methylphenyl)-methanone. Grades: Highly Purified. CAS No. 134612-39-8. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
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