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| Product | Description | |
|---|---|---|
| Tolcapone | Tolcapone functions as a selective peripheral and central COMT inhibitor, exerting no effect on adrenergic, serotonergic, or cholinergic receptors or other enzymes involved in synthesis or catabolism of catecholamines. Synonyms: Ro 40-7592; Ro40-7592; Ro-40-7592. Grades: >98%. CAS No. 134308-13-7. Molecular formula: C14H11NO5. Mole weight: 273.24. |  |
| Tolcapone | Tolcapone (Ro 40-7592) is a selective, orally active and powerful mixed (peripheral and central) COMT inhibitor with an IC 50 of 773?nM in the liver [1]. Tolcapone is also a potent inhibitor of α-syn and Aβ42 oligomerization and fibrillogenesis [2]. Tolcapone induces oxidative stress leading to apoptosis and inhibition of tumor growth in neuroblastoma [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 40-7592. CAS No. 134308-13-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17406. |  |
| Tolcapone ( (3, 4-Dihydroxy-5-nitro-phenyl) (4-methylphenyl) methanone, Ro-40-7592, Tasmar) | Orally active inhibitor of central and peripheral catechol-O-methyltransferase (COMT). Antiparkinsonian. Group: Biochemicals. Alternative Names: (3, 4-Dihydroxy-5-nitro-phenyl) (4-methylphenyl) methanone; Ro-40-7592; Tasmar. Grades: Highly Purified. CAS No. 134308-13-7. Pack Sizes: 100mg. US Biological Life Sciences. |  Worldwide |
| Tolcapone 3-β-D-Glucuronide | One of the impurities of Tolcapone, which is a COMT inhibitor and has been found to be active in antiparkinsonian studies. Synonyms: 2-Hydroxy-5-(4-methylbenzoyl)-3-nitrophenyl β-D-Glucopyranosiduronic Acid. CAS No. 204853-33-8. Molecular formula: C20H19NO11. Mole weight: 449.37. | |
| Tolcapone-d4 | Orally active inhibitor of central and peripheral catechol-O-methyltransferase (COMT). Antiparkinsonian. Group: Biochemicals. Alternative Names: (3,4-Dihydroxy-5-nitrophenyl)(4-methylphenyl-d4)methanone; Ro-40-7592-d4; Tasmar-d4. Grades: Highly Purified. CAS No. 1246816-93-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Tolcapone Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. |  |
| Tolcapone Related Compound B | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Tolcapone USP | Tolcapone USP. CAS No. 134308-13-7. Product ID: 2-08500. Molecular formula: C14H11NO5. Mole weight: 273.24. Properties: yellow powder mp 126-128ºC. Source : therapeutic agent for Parkinsons disease, CNS agent, reversible enzyme inhibitor. |  |
| 3-O-Benzyl-4-O-methyl Tolcapone-d4 | 3-O-Methyl Tolcapone derivative. A metabolite of catechol-O-Methyl transferase inhibitor Tolcapone. Group: Biochemicals. Alternative Names: (3-Benzyloxy-4-methoxy-5-nitrophenyl)(4-methylphenyl)methanone-d4; 3-Benzyloxy-4-methoxy-4'-methyl-5-nitrobenzophenone-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 3-O-Methyl tolcapone | 3-O-Methyl tolcapone. Group: Biochemicals. Alternative Names: (4-Hydroxy-3-methoxy-5-nitrophenyl) (4-methylphenyl) methanone; 4-Hydroxy-3-methoxy-4'-methyl-5-nitrobenzophenone; Ro 40-7591. Grades: Highly Purified. CAS No. 134612-80-9. Pack Sizes: 25mg, 50mg. Molecular Formula: C15H13NO5. US Biological Life Sciences. | Worldwide |
| 3-O-Methyl Tolcapone | One of the impurities of Tolcapone, which is a COMT inhibitor and has been found to be active in antiparkinsonian studies. Synonyms: 4-Hydroxy-3-methoxy-4'-methyl-5-nitrobenzophenone; (4-Hydroxy-3-methoxy-5-nitrophenyl)(4-methylphenyl)methanone. CAS No. 134612-80-9. Molecular formula: C15H13NO5. Mole weight: 287.27. | |
| 3-O-Methyl Tolcapone-d4 | 3-O-Methyl Tolcapone-d4. Group: Biochemicals. Alternative Names: (4-Hydroxy-3-methoxy-5-nitrophenyl)(4-methylphenyl)methanone-d4; 4-Hydroxy-3-methoxy-4'-methyl-5-nitrobenzophenone-d4; Ro 40-7591-d4. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C15H9D4NO5, Molecular Weight: 291.29. US Biological Life Sciences. | Worldwide |
| 3-Benzyloxy-4-methoxy-4'-methylbenzophenone | Intermediate in the preparation of Tolcapone and its derivatives. Group: Biochemicals. Alternative Names: (3-Benzyloxy-4-methoxyphenyl)(4-methylphenyl)-methanone. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 3-Benzyloxy-4-methoxy-4'-methylbenzophenone-d4 | Intermediate in the preparation of Tolcapone and its derivatives. Group: Biochemicals. Alternative Names: (3-Benzyloxy-4-methoxyphenyl)(4-methylphenyl)-methanone-d4. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 4-Hydroxy-3-methoxy-4'-methylbenzophenone | Intermediate in the preparation of Tolcapone and its derivatives. Group: Biochemicals. Alternative Names: (4-Hydroxy-3-methoxyphenyl)(4-methylphenyl)-methanone. Grades: Highly Purified. CAS No. 134612-39-8. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Varenicline carbamoyl glucuronide | Varenicline carbamoyl glucuronide is a metabolite of Varenicline. Varenicline is a partial agonist of nicotinic receptor used for smoking cessation. It reduces both the desire for and the pleasure of cigarettes. Synonyms: Varenicline carbamoyl beta-D-glucuronide; Varenicline Carbamoyl-ß-D-glucuronide; Tolcapone 3-ß-D-Glucuronide; 1-(6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-carboxylate)β-D-Glucopyranuronic Acid; Metabolite M4. Grades: 98%. CAS No. 535920-98-0. Molecular formula: C20H21N3O8. Mole weight: 431.40. | |
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