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Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels , increases in potassium conductance, and inhibition of carbonic anhydrase [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: McN 4853; RWJ 17021. CAS No. 97240-79-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0122.
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: 2,3-O-(1-Methylethylidene)-b-D-fructopyranose 1-sulfamate Topiramate desacetal impurity. CAS No. 106881-41-8. Molecular formula: C9H17NO8S. Mole weight: 299.30.
Topiramate D-galactopyranose
Topiramate D-galactopyranose is a scientifically formulated pharmaceutical compound, used for studying epilepsy and migraine headaches. Marrying the prowess of anticonvulsant properties and the ability to curb repetitive neuronal firing, it exhibits a mechanism of action rooted in augmenting GABA receptor activity while diminishing glutamate receptor activity. Molecular formula: C18H31NO13S. Mole weight: 501.50.
Topiramate Didesacetal Impurity
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: β-D-Fructopyranose 1-Sulfamate. CAS No. 106881-42-9. Molecular formula: C6H13NO8S. Mole weight: 259.24.
Topiramate Dimer Impurity
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Molecular formula: C24H39NO13S. Mole weight: 581.63.
Topiramate EP Impurity A
Topiramate EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ((3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methanol. CAS No. 20880-92-6. Molecular Formula: C12H20O6. Mole Weight: 260.28. Catalog: APB20880926.
Topiramate EP Impurity B
Topiramate EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 876403-98-4. Molecular Formula: C17H30N2O9S. Mole Weight: 438.49. Catalog: APB876403984.
Topiramate EP Impurity C
Topiramate EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106881-41-8. Molecular Formula: C9H17NO8S. Mole Weight: 299.29. Catalog: APB106881418.
Topiramate EP Impurity D
Topiramate EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 950603-46-0. Molecular Formula: C25H39NO15S. Mole Weight: 625.64. Catalog: APB950603460.
Topiramate EP Impurity E
Topiramate EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Lactulose EP Impurity D. CAS No. 57-48-7. Molecular Formula: C6H12O6. Mole Weight: 180.06. Catalog: APB57487.
Topiramate Impurity 1
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: 2,3. CAS No. 106881-35-0. Molecular formula: C12H19N3O8S. Mole weight: 365.36.
Topiramate Impurity 10
Topiramate Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 35405-70-0. Molecular Formula: C24H39NO13S. Mole Weight: 581.63. Catalog: APB35405700.
Topiramate Impurity 12
Topiramate Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106881-42-9. Molecular Formula: C6H13NO8S. Mole Weight: 259.23. Catalog: APB106881429.
Topiramate Impurity 14
Topiramate Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3aR,6R,7S,7aS)-6-(hydroxymethyl)-2,2-dimethyltetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-6,7-diol. CAS No. 912456-61-2. Molecular Formula: C9H16O6. Mole Weight: 220.22. Catalog: APB912456612.
Topiramate Impurity 16
Topiramate Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10489-81-3. Molecular Formula: C6H12O6. Mole Weight: 180.16. Catalog: APB10489813.
Topiramate Impurity 17
Topiramate Impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 58238-46-3. Molecular Formula: C9H16O6. Mole Weight: 220.22. Catalog: APB58238463.
Topiramate Impurity 18
Topiramate Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 38029-84-4. Molecular Formula: C6H12O6. Mole Weight: 180.16. Catalog: APB38029844.
Topiramate Impurity 2
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: 4,5-O-(1-Methylethylidene)-b-D-fructopyranose 1-sulfamate. CAS No. 851957-35-2. Molecular formula: C9H17NO8S. Mole weight: 299.30.
Topiramate Impurity 6
Topiramate Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ((3aR,6R,7S,7aS)-6,7-dihydroxy-2,2-dimethyltetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-6-yl)methyl sulfamate. CAS No. 851957-35-2. Molecular Formula: C9H17NO8S. Mole Weight: 299.30. Catalog: APB851957352.
Topiramate impurity B
Topiramate Impurity B is a pharmaceutical offering, aiding in anchoring the assessment of quality and purity within topiramate formulations, an eminent remedy for epilepsy research and migraine prophylaxis. Synonyms: Topiramate related compound B.
Topiramate impurity C
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: (2,2,7,7-tetramethyl-tetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d] pyran-3a-yl)methyl sulfurochloridoate. Molecular formula: C12H19ClO8S. Mole weight: 358.79.
Topiramate Impurity D
Cas No. 25018-67-1.
Topiramate N-Methyl Impurity
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: N-Methyl Topiramate; 2,3:4,5-bis-O-(1-Methylethylidene)-β-D-Fructopyranose 1-(N-Methylsulfamate); 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose Methylsulfamate. CAS No. 97240-80-7. Molecular formula: C13H23NO8S. Mole weight: 353.39.
Topiramate Related Compound A
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: 2,3:4,5-Di-O-isopropylidene-β-D-fructopyranose; 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose; USP Topiramate Related Compound A; Diacetonefructose; ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methanol. Grades: ≥98%. CAS No. 20880-92-6. Molecular formula: C12H20O6. Mole weight: 260.28.
2,3-Desisopropylidene Topiramate
A metabolite of Topiramate. Group: Biochemicals. Alternative Names: 4,5-O-(1-Methylethylidene)- β-D-fructopyranose 1-Sulfamate. Grades: Highly Purified. CAS No. 851957-35-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
4,5-Desisopropylidene Topiramate
A metabolite of Topiramate. Group: Biochemicals. Alternative Names: 2,3-O-(1-Methylethylidene)- β-D-fructopyranose 1-Sulfamate. Grades: Highly Purified. CAS No. 106881-41-8. Pack Sizes: 1mg. US Biological Life Sciences.
r-Hydroxy topiramate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 10-Hydroxy Topiramate;4,5-O-[(1R)-2-Hydroxy-1-methylethylidene]-2,3-O-(1-methylethylidene)-b-D-fructopyranose 1-Sulfamate;4,5-O-[(1R)-2-Hydroxy-1-methylethylidene]-2,3-O-(1-methylethylidene)--D-fructopyranose 1-Sulfamate;R-Hydroxy Topiramate. Product Category: Heterocyclic Organic Compound. CAS No. 198215-60-0. Molecular formula: C12H21NO9S. Mole weight: 355.362. Purity: 0.96. IUPACName: [(3aS,5aR,7S,8aR,8bS)-7-(hydroxymethyl)-2,2,7-trimethyl-5,5a,8a,8b-tetrahydrodi[1,3]dioxolo[4,5-a:5',3'-d]pyran-3a-yl]methylsulfamate. Canonical SMILES: CC1(OC2C3C(COC2(O1)COS(=O)(=O)N)OC(O3)(C)CO)C. Product ID: ACM198215600. Alfa Chemistry ISO 9001:2015 Certified.
R-Hydroxy topiramate
R-Hydroxy topiramate, a pharmaceutical compound effective in managing epilepsy and migraines, demonstrates its potential as an anticonvulsant drug derivative. By modulating neuronal activity within the brain, it successfully diminishes seizure episodes and averts the onset of migraines. Synonyms: 4,5-O-[(1R)-2-Hydroxy-1-methylethylidene]-2,3-O-(1-methylethylidene)-b-D-fructopyranose 1-sulfamate; 10-Hydroxy topiramate. CAS No. 198215-60-0. Molecular formula: C12H21NO9S. Mole weight: 355.36.
R-Hydroxy Topiramate
A metabolite of Topiramate. Group: Biochemicals. Alternative Names: 4,5-O-[(1R)-2-Hydroxy-1-methylethylidene]-2,3-O-(1-methylethylidene)- β-D-fructopyranose 1-Sulfamate; 10-Hydroxy Topiramate. Grades: Highly Purified. CAS No. 198215-60-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
S-Hydroxy topiramate
S-Hydroxy topiramate, a formidable medicinal entity, emerges as an efficacious intervention for the amelioration of epileptic phenomena and migraine-related cephalalgia. Its mechanism revolves around impeding deviant cerebral conduct, consequently mitigating the frequency of paroxysmal episodes. Owing to its antiepileptic properties, S-Hydroxy topiramate serves as a proficient agent in the comprehensive management of diverse seizure classifications, encompassing both focal and generalized presentations. Synonyms: 4,5-O-[(1S)-2-Hydroxy-1-methylethylidene]-2,3-O-(1-methylethylidene)-b-D-fructopyranose 1-sulfamate; 9-Hydroxy topiramate. CAS No. 198215-62-2. Molecular formula: C12H21NO9S. Mole weight: 355.36.
S-Hydroxy Topiramate
A metabolite of Topiramate. Group: Biochemicals. Alternative Names: 4,5-O-[(1S)-2-Hydroxy-1-methylethylidene]-2,3-O-(1-methylethylidene)- β-D-fructopyranose 1-Sulfamate; 9-Hydroxy Topiramate. Grades: Highly Purified. CAS No. 198215-62-2. Pack Sizes: 1mg. US Biological Life Sciences.
2,3:4,5-bis-O-(1-Methylethylidene)-1-chlorosulfate β-D-Fructopyranose is an intermediate for Topiramate-d12 (T540252) and an impurity of Topiramate(T540250). Topiramate is used as an anticonvulsant. Group: Biochemicals. Grades: Highly Purified. CAS No. 150609-95-3. Pack Sizes: 500mg, 5g. Molecular Formula: C12H19ClO8S. US Biological Life Sciences.
2,3:4,5-Bis-O-(1-methylethylidene)- β-D-fructopyranose 1-[[ (diethylamino) carbonyl]sulfamate] is an impurity of Topiramate (T540250), which is used as an anti-convulsant. Group: Biochemicals. Grades: Highly Purified. CAS No. 876403-98-4. Pack Sizes: 25mg, 100mg. Molecular Formula: C17H30N2O9S, Molecular Weight: 438.49. US Biological Life Sciences.
Intermediate in the preparation of 2,3-Desisopropylidene Topiramate, a metabolite of Topiramate. Molecular formula: C25H34O6Si. Mole weight: 458.62.
D-Fructopiranose Hydrochloride
D-fructopiranose hydrochloride is an impurity from topiramate chloride which is a potent anticonvulsant. Synonyms: β-D-Fructopyranose deriv. 5H-Bis[1,3]dioxolo[4,5-b:4',5'-d]pyran; 1-Chloro-1-deoxy-2,3:4,5-di-O-isopropylidene-β-D-fructopyranose. Molecular formula: C12H19ClO5. Mole weight: 278.73.
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