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Topiramate is a kainate GluR5 receptor antagonist, originally used as an anticonvulsant. Synonyms: 2,3:4,5-Bis-O-(1-methylethylidene)-36-D-fructo-pyranose sulfamate. Grade: >98%. CAS No. 97240-79-4. Molecular formula: C12H21NO8S. Mole weight: 339.37.
Topiramate
Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels , increases in potassium conductance, and inhibition of carbonic anhydrase [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: McN 4853; RWJ 17021. CAS No. 97240-79-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0122.
Topiramate-[13C6]
An isotope labelled of Topiramate. Topiramate is an anticonvulsant drug. Synonyms: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl-3a,5,5a,8a,8b-13C5)methyl-13C sulfamate. Grade: 98% by CP. CAS No. 1217455-55-4. Molecular formula: C6[13C]6H21NO8S. Mole weight: 345.32.
Topiramate-[d12]
An isotope labelled form of Topiramate. Topiramate is an anticonvulsant drug. It can be used for the treatment of epilepsy. Synonyms: 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fuctopyranose-d12 1-Sulfamate; Epitoma-d12; Epitomax-d12; McN 4853-d12; RWJ 17021-d12; TPM-d12; Topamac-d12; Topamax-d12; Topimax-d12; Topina-d12; Topomax-d12. Grade: 98% by HPLC; 99% atom D. CAS No. 1279037-95-4. Molecular formula: C12H9D12NO8S. Mole weight: 351.44.
Topiramate-D12 solution
100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms).
Topiramate EP Impurity C
Topiramate EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106881-41-8. Molecular formula: C9H17NO8S. Mole weight: 299.29. Catalog: APB106881418.
Topiramate Impurity 12
Topiramate Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106881-42-9. Molecular formula: C6H13NO8S. Mole weight: 259.23. Catalog: APB106881429.
Topiramate Impurity 16
Topiramate Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10489-81-3. Molecular formula: C6H12O6. Mole weight: 180.16. Catalog: APB10489813.
Topiramate Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
2,3-Desisopropylidene Topiramate
A metabolite of Topiramate. Group: Biochemicals. Alternative Names: 4,5-O-(1-Methylethylidene)- β-D-fructopyranose 1-Sulfamate. Grades: Highly Purified. CAS No. 851957-35-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
2,3-Desisopropylidene Topiramate
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: 4,5-O-(1-Methylethylidene)-b-D-fructopyranose 1-sulfamate. CAS No. 851957-35-2. Molecular formula: C9H17NO8S. Mole weight: 299.30.
4,5-Desisopropylidene Topiramate
A metabolite of Topiramate. Group: Biochemicals. Alternative Names: 2,3-O-(1-Methylethylidene)- β-D-fructopyranose 1-Sulfamate. Grades: Highly Purified. CAS No. 106881-41-8. Pack Sizes: 1mg. US Biological Life Sciences.
r-Hydroxy topiramate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 10-Hydroxy Topiramate;4,5-O-[(1R)-2-Hydroxy-1-methylethylidene]-2,3-O-(1-methylethylidene)-b-D-fructopyranose 1-Sulfamate;4,5-O-[(1R)-2-Hydroxy-1-methylethylidene]-2,3-O-(1-methylethylidene)--D-fructopyranose 1-Sulfamate;R-Hydroxy Topiramate. Product Category: Heterocyclic Organic Compound. CAS No. 198215-60-0. Molecular formula: C12H21NO9S. Mole weight: 355.362. Purity: 0.96. IUPACName: [(3aS,5aR,7S,8aR,8bS)-7-(hydroxymethyl)-2,2,7-trimethyl-5,5a,8a,8b-tetrahydrodi[1,3]dioxolo[4,5-a:5',3'-d]pyran-3a-yl]methylsulfamate. Canonical SMILES: CC1(OC2C3C(COC2(O1)COS(=O)(=O)N)OC(O3)(C)CO)C. Product ID: ACM198215600. Alfa Chemistry ISO 9001:2015 Certified.
R-Hydroxy Topiramate
A metabolite of Topiramate. Group: Biochemicals. Alternative Names: 4,5-O-[(1R)-2-Hydroxy-1-methylethylidene]-2,3-O-(1-methylethylidene)- β-D-fructopyranose 1-Sulfamate; 10-Hydroxy Topiramate. Grades: Highly Purified. CAS No. 198215-60-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
S-Hydroxy Topiramate
A metabolite of Topiramate. Group: Biochemicals. Alternative Names: 4,5-O-[(1S)-2-Hydroxy-1-methylethylidene]-2,3-O-(1-methylethylidene)- β-D-fructopyranose 1-Sulfamate; 9-Hydroxy Topiramate. Grades: Highly Purified. CAS No. 198215-62-2. Pack Sizes: 1mg. US Biological Life Sciences.
1-Chloro-1-deoxy-2,3:4,5-di-O-isopropylidene-β-D-fructopyranose is an impurity from topiramate chloride, which is a potent anticonvulsant. Synonyms: D-Fructopiranose Hydrochloride; β-D-Fructopyranose, 1-chloro-1-deoxy-2,3:4,5-bis-O-(1-methylethylidene)-; 1-Chloro-1-deoxy-2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose; Fructopyranose, 1-chloro-1-deoxy-2,3:4,5-di-O-isopropylidene-, β-D-. CAS No. 32785-90-3. Molecular formula: C12H19ClO5. Mole weight: 278.73.
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Grade: 95%. CAS No. 128316-82-5. Molecular formula: C12H21NO5. Mole weight: 259.30.
2,3:4,5-bis-O-(1-Methylethylidene)-1-chlorosulfate β-D-Fructopyranose is an intermediate for Topiramate-d12 (T540252) and an impurity of Topiramate(T540250). Topiramate is used as an anticonvulsant. Group: Biochemicals. Grades: Highly Purified. CAS No. 150609-95-3. Pack Sizes: 500mg, 5g. Molecular Formula: C12H19ClO8S. US Biological Life Sciences.
2,3:4,5-Bis-O-(1-methylethylidene)- β-D-fructopyranose 1-[[ (diethylamino) carbonyl]sulfamate] is an impurity of Topiramate (T540250), which is used as an anti-convulsant. Group: Biochemicals. Grades: Highly Purified. CAS No. 876403-98-4. Pack Sizes: 25mg, 100mg. Molecular Formula: C17H30N2O9S, Molecular Weight: 438.49. US Biological Life Sciences.
An intermediate in the preparation of 2,3-Desisopropylidene Topiramate, a metabolite of Topiramate. Synonyms: (3aR,6R,7R,7aR)-7-(benzyloxy)-6-(hydroxymethyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyran-6-ol. Molecular formula: C16H22O6. Mole weight: 310.34.
Intermediate in the preparation of 2,3-Desisopropylidene Topiramate, a metabolite of Topiramate. Synonyms: 3-tert-Butyldiphenylsilyl-4,5-O-(1-methylethyldiene)-β-D-fructopyranose; 3-O-tert-Butyldiphenylsilyl-4,5-O-(1-methylethylidene)-β-D-fructopyranose; (3aR,6R,7S,7aR)-7-((tert-butyldiphenylsilyl)oxy)-6-(hydroxymethyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyran-6-ol. Molecular formula: C25H34O6Si. Mole weight: 458.62.
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