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| Product | Description | |
|---|---|---|
| Tranylcypromine Hemisulfate (Trans (±) -2-Phenyl cyclopropanamine, Hemisulfate; SKF trans-355; 2-PCPA) | An inhibitor of monoamine oxidase (MAO) and prostacyclin synthase. Potently suppresses the enzymatic activity of Lysine-Specific Demethylase 1 (LSD1) (IC50 <2uM for BHC110/LSD1). When combined with GSK-3 Inhibitor CHIR99021, causes reprogramming of human primary keratinocyte transduced with two factors, Oct4 and Klf4. Group: Biochemicals. Alternative Names: Trans (±) -2-Phenyl cyclopropanamine, Hemisulfate; SKF trans-355; 2-PCPA. Grades: Highly Purified. CAS No. 13492-01-8. Pack Sizes: 25mg. US Biological Life Sciences. |  Worldwide |
| Tranylcypromine hydrochloride | Tranylcypromine hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1986-47-6. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Tranylcypromine hydrochloride | Tranylcypromine hydrochloride (SKF 385 hydrochloride) is an irreversible inhibitor of lysine-specific demethylase 1 (LSD1/BHC110) and monoamine oxidase (MAO). Tranylcypromine hydrochloride inhibits LSD1, MAO A and MAO B with IC 50 s of 20.7, 2.3 and 0.95 μM, respectively. Tranylcypromine hydrochloride can be used for the research of depression [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF 385 hydrochloride. CAS No. 1986-47-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-17447A. |  |
| Tranylcypromine hydrochloride | Tranylcypromine is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and human liver microsomes, respectively. Synonyms: (1R,2S)-2-phenylcyclopropan-1-amine;hydrochloride. Grades: > 98 %. CAS No. 1986-47-6. Molecular formula: C9H12ClN. Mole weight: 169.65. |  |
| (1R,2S)-Tranylcypromine-d5 Hydrochloride | Unlabeled (1R,2S)-Tranylcypromine-d5 Hydrochloride is used in the preparation of piperidine derivatives, which serve as LSD1 inhibitors for the treatment of cancer. Unlabeled (1R,2S)-Tranylcypromine-d5 Hydrochloride has also been shown to inhibit gastric emptying in rats. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C9H6D5N.HCl, Molecular Weight: 138.123646. US Biological Life Sciences. | Worldwide |
| (1S,2R)-Tranylcypromine-d5 Hydrochloride | (1S,2R)-Tranylcypromine Hydrochloride (T715000) is used in the preparation of piperidine derivatives, which serve as LSD1 inhibitors for the treatment of cancer.(1S,2R)-Tranylcypromine Hydrochloride (T715000) has been shown to increase monoamine oxidase inhibition andinhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C9H6D5N.HCl, Molecular Weight: 138.123646. US Biological Life Sciences. | Worldwide |
| trans 2-Phenylcyclopropylamine Hydrochloride (Tranylcypromine, trans 2-Amino-1-phenyl-cyclopropane Hydrochloride) | A non-selective inhibitor of monoamine oxidase (MAO) and prostacyclin synthase. Potently suppresses the enzymatic activity of Lysine-Specific Demethylase 1 (LSD1) (IC50 <2uM for BHC110/LSD1). When combined with GSK-3 Inhibitor CHIR99021, causes reprogramming of human primary keratinocyte transduced with two factors, Oct4 and Klf4. Group: Biochemicals. Alternative Names: Tranylcypromine; trans 2-Amino-1-phenyl-cyclopropane Hydrochloride. Grades: Highly Purified. CAS No. 1986-47-6. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| trans 2-(Phenyl-d5)-cyclopropylamine Hydrochloride (Tranylcypromine-d5, trans 2-Amino-1-(phenyl-d5)-cyclopropane Hydrochloride) | Non-selective MAO-A/B inhibitor. Group: Biochemicals. Alternative Names: Tranylcypromine-d5; trans 2-Amino-1-(phenyl-d5)-cyclopropane Hydrochloride. Grades: Highly Purified. CAS No. 107077-98-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| (-)-Tranylcypromine HCl | One isomer form of Tranylcypromine, which has been found to be a monoamine oxidase inhibitor and could be used as an anti-depressant agent. Synonyms: cis-2-Phenylcyclopropanamine hydrochloride. Molecular formula: C9H12ClN. Mole weight: 169.65. | |
| (+)-Tranylcypromine HCl | One isomer form of Tranylcypromine, which has been found to be a monoamine oxidase inhibitor and could be used as an anti-depressant agent. Synonyms: trans-Tranylcypromine Hydrochloride; trans 2-Amino-1-phenyl-cyclopropane Hydrochloride; 2-PCPA Hydrochloride. Molecular formula: C9H12ClN. Mole weight: 169.65. | |
| CHIR-99021 | CHIR-99021 (CT99021) is a glycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative activity in vitro and in vivo. It enhances reprogramming of mouse embryonic fibroblasts, transduced by Oct4 and Klf4 only, into iPSCs in combination with tranylcypromine. It also induces cardiomyocyte differentiation from human embryonic stem (ES). Uses: Potential antineoplastic agent. Synonyms: CHIR-99021; CT99021; 6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile. Grades: >98%. CAS No. 252917-06-9. Molecular formula: C22H18Cl2N8. Mole weight: 465.342. | |
| Cinnamylamine Hydrochloride | Cinnamylamine Hydrochloride, can be used for the preparation of Tranylcypromine, a drug that acts as a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO), and is used as an antidepressant and anxiolytic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 5586-89-0. Pack Sizes: 25mg, 100mg. Molecular Formula: C9H12ClN, Molecular Weight: 169.65. US Biological Life Sciences. | Worldwide |
| iPSC Induction Enhancer II, OAC1 N-(1H-Pyrrolo[2,3-c]pyridin-5-yl)benzamide, Induced Pluripotent Stem Cells Induction Enhancer II, Oct4-Activating Compound 1) | A cell-permeable pyrrolopyridinyl-benzamide compound that is reported to enhance the efficiency of 4F/4TF-induced iPSC generation from MEFs cultured in either feeder cell-containing ESC media or in feeder-/serum-free iSF1 media (1uM OAC1 treatment starts 48h after viral transduction). OCA1 is shown to increase cellular Oct4, Nanog, Sox2, and Tet1 mRNA levels via a yet unidentified mechanism, although OAC1 is reported not affect Oct4 promoter methylation, cellular Wnt signaling, or p53 and p21 mRNA levels. Six other iPSC reprogramming improving reagents, AM580, AzaC, BIX-01294, Tranylcypromine, VPA, and Vitamin C, in comparison, do not exhibit Oct4 and Nanog promoters enhancing activity, while BIO is demonstrated to be 3.8- and 6-fold less potent than OAC1, respectively, in inducing Oct4 and Nanog transcription. Group: Biochemicals. Grades: Highly Purified. CAS No. 300586-90-7. Pack Sizes: 25mg. Molecular Formula: C??H??N?O, Molecular Weight: 237.3. US Biological Life Sciences. | Worldwide |
| LSD1 Inhibitor IV, RN-1,HCl (2- (1R, 2S) -2- (4- (Benzyloxy) phenyl) cyclopropylamino) -1- (4-methylpiperazin-1-yl) ethanone, HCl, Lysine (K)-Specific Demethylase Inhibitor IV,RN-1,HCl, BHC110 Inhibitor IV, KDM1 Inhibitor IV, MOA Inhibitor III) | A cell-permeable tranylcypromine (parnate) analog that acts as a potent, irreversible inhibitor of lysine specific demethylase 1 (LSD1; IC50=70nM in a HRP-coupled assay using H3K4Me2 peptide substrate). Forms a covalent adduct with flavin adenine dinucleotide (FAD). Shown to cross the blood brain barrier. Exhibits moderate selectivity over amine oxidases MAO-A and MAO-B (IC50=0.51 and 2.785uM, respectively). Displays desirable pharmacokinetic properties (brain/plasma exposure ratio of 88.9), and impairs long-term memory without affecting short-term memory in mice (10mg/kg, i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| rac cis-2-Phenylcyclopropylamine Hydrochloride | cis-2-Phenylcyclopropylamine is a derivative of the amphetamine class of drugs. cis-2-Phenylcyclopropyl amineis a non-selective MAO-A/B inhibitor. Group: Biochemicals. Alternative Names: cis-Tranylcypromine Hydrochloride; cis-2-Amino-1-phenyl-cyclopropane Hydrochloride; (1R,2R)-rel-Phenylcyclopropylamine Hydrochloride. Grades: Highly Purified. CAS No. 54779-58-7. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| rac trans 2-phenylcyclopropylamine hydrochloride | rac trans 2-phenylcyclopropylamine hydrochloride. Group: Biochemicals. Alternative Names: Tranylcypromine; trans 2-Amino-1-phenyl-cyclopropane hydrochloride. Grades: Highly Purified. CAS No. 1986-47-6. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C9H12ClN. US Biological Life Sciences. | Worldwide |
| S2116 | S2116, a N-alkylated tranylcypromine (TCP) derivative, is a potent lysine-specific demethylase 1 (LSD1) inhibitor. S2116 increases H3K9 methylation and reciprocal H3K27 deacetylation at super-enhancer regions. S2116 induces apoptosis in TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells by repressing transcription of the NOTCH3 and TAL1 genes. S2116 significantly retardes the growth of T-ALL cells in xenotransplanted mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2262489-89-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136522. | |
| trans-2-(Phenyl-D5)cyclopropylamine hydroChloride | Heterocyclic Organic Compound. Alternative Names: trans 2-(Phenyl-D5)-cyclopropylamine Hydrochloride;trans 2-Amino-1-(phenyl-d5)-cyclopropane Hydrochloride;Tranylcypromine-d5;rac trans 2-cyclopropylamine Hydrochloride d5. CAS No. 107077-98-5. Molecular formula: C9H6D5N.HCl. Mole weight: 174.68. Appearance: Pale Brown Solid. Purity: 98 atom % D. IUPACName: (1R,2S)-2-(2,3,4,5,6-pentadeuteriophenyl)cyclopropan-1-amine;hydrochloride. Catalog: ACM107077985. |  |
| Tranylcipromine | Tranylcypromine, an amphetamine derivative, has been found to be a MAO inhibitor that could be used an antidepressant agent and anxiolytic drug. Synonyms: Cyclopropanamine, 2-phenyl-, (1R,2S)-rel-;Tranylcypromine (base and/or unspecified salts);dl-Tranylcypromine;SKF-385;Transamine[thymoleptic];C07155. Grades: 98%. CAS No. 155-09-9. Molecular formula: C9H11N. Mole weight: 133.19. | |
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