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(2-(1,3-Dithiolan-2-yl)-Trp25)-Liraglutide trifluoroacetate salt
(2-(1,3-Dithiolan-2-yl)-Trp25)-Liraglutide trifluoroacetate salt is an impurity of Liraglutide. Synonyms: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-2-(1,3-dithiolan-2-yl)-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH trifluoroacetate salt. Molecular formula: C175H269N43O51S2.C2HF3O2. Mole weight: 3969.41.
(2-(2-Trifluoromethyl-1,3-dithiolan-2-yl)-Trp25)-Liraglutide trifluoroacetate salt
(2-(2-Trifluoromethyl-1,3-dithiolan-2-yl)-Trp25)-Liraglutide trifluoroacetate salt is an impurity of Liraglutide. Synonyms: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-2-(2-trifluoromethyl-1,3-dithiolan-2-yl)-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH trifluoroacetate salt. Molecular formula: C176H268F3N43O51S2.C2HF3O2. Mole weight: 4037.41.
2-Amino-3-butenoic acid trifluoroacetate salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-AMINO-3-BUTENOIC ACID TRIFLUOROACETATE SALT;DL-VINYLGLYCINE TRIFLUOROACETATE SALT;dl-vinylglycine trifluoroacetate. Product Category: Heterocyclic Organic Compound. CAS No. 166301-19-5. Molecular formula: C6H8F3NO4. Mole weight: 215.13. Product ID: ACM166301195. Alfa Chemistry ISO 9001:2015 Certified.
2-Furoyl-LIGRLO amide trifluoroacetate salt
2-Furoyl-LIGRLO amide is a potent and selective agonist of the proteinase-activated receptor, PAR2 (pD2 = 7.0). Grades: ≥95%. Molecular formula: C36H63N11O8·xCF3COOH. Mole weight: 777.9.
(2-Hydroxy-Trp25)-Liraglutide trifluoroacetate salt
(2-Hydroxy-Trp25)-Liraglutide trifluoroacetate salt is an impurity of Liraglutide. Synonyms: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-2-hydroxy-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C172H265N43O52.C2HF3O2. Mole weight: 3881.21.
(2R)-2-Amino-4-methyl-1-[(2R)-2-methyloxiran-2-yl]pentan-1-one Trifluoroacetate Salt
(2R)-2-Amino-4-methyl-1-(2-methyloxiran-2-yl)pentan-1-one Trifluoroacetate Salt s an impurity of carfilzomib (C183460). Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C11H18F3NO4, Molecular Weight: 285.26. US Biological Life Sciences.
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(2S,4R)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate Trifluoroacetate Salt
(2S,4R)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate Trifluoroacetate Salt is an intermediate in synthesizing Carfilzomib (2S,4R)-Diol (C183500), a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C11H21NO4; (C2HF3O2), Molecular Weight: 231.2911402. US Biological Life Sciences.
AAF-CMK is a serine protease inhibitor which irreversibly inhibits TPPII (tripeptidyl peptidase II), a giant protease which may substitute for some proteasome function, and reversibly inhibits Cln2 (TPPI). Synonyms: N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase Inhibitor II; L-Alaninamide,L-alanyl-N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-. Grades: ≥95%. CAS No. 184901-82-4. Molecular formula: C18H23ClF3N3O5. Mole weight: 453.84.
Abz-FRK(Dnp)P-OH trifluoroacetate salt
?95% (HPLC), film. Group: Fluorescence/luminescence spectroscopy.
Abz-LFK(Dnp)-OH trifluoroacetate salt is an angiotensin-converting enzyme (ACE) fluorescent peptide substrate that binds specifically to the C domain of ACE. It has been used to investigate the development of novel antibacterial calixarene derivatives, as well as the efficacy and toxicity of antimicrobial peptide M33 as a possible antimicrobial agent for lung infections and sepsis. Synonyms: O-Aminobenzoic acid-Leu-Phe-Lys(DNP)-OH trifluoroacetate salt; Abz-Leu-Phe-Lys-DNP trifluoroacetate salt; (2-aminobenzoyl)-L-leucyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine trifluoroacetic acid; N-(2-Aminobenzoyl)-L-leucyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine trifluoroacetate (1:1); L-Lysine, N-(2-aminobenzoyl)-L-leucyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-, compd. with 2,2,2-trifluoroacetic acid (1:1); (2S)-2-[[(2S)-2-([(2S)-2-[(2-Aminobenzoyl)amino]-4-methylpentanoyl]amino)-3-phenylpropanoyl]amino]-6-(2,4-dinitroanilino)hexanoic acid trifluoroacetate. Grades: ≥97% by HPLC. CAS No. 1217437-31-4. Molecular formula: C34H41N7O9.C2HF3O2. Mole weight: 805.76.
Ac-AAVALLPAVLLALLAP-DEVD-CHO trifluoroacetate salt
Ac-AAVALLPAVLLALLAP-DEVD-CHO is a composite of Ac-DEVD-CHO, a peptide inhibitor of caspase-3 and -7, and a cell-permeable hydrophobic sequence derived from K-FGF. Synonyms: Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Glu-Val-Asp-CHO; Ac-AAVALLPAVLLALLAP-DEVD-aldehyde; Ac-AAVALLPAVLLALLAPDEVD-CHO; ?Caspase-3 Inhibitor I; DEVD-CHO-CPP 32. Grades: ≥95%. Molecular formula: C94H158N20O27·xCF3COOH. Mole weight: 2000.42.
Ac-AAVALLPAVLLALLAP-IETD-CHO trifluoroacetate salt
Ac-AAVALLPAVLLALLAP-IETD-CHO is a composite of Ac-IETD-CHO, a peptide inhibitor of caspase-8, and a cell-permeable hydrophobic sequence derived from K-FGF. Synonyms: Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-CHO; Caspase-8 Inhibitor I. Grades: ≥95%. Molecular formula: C95H162N20O26·xCF3COOH. Mole weight: 2000.40.
Ac-AAVALLPAVLLALLAP-VAD-CHO trifluoroacetate salt
Ac-AAVALLPAVLLALLAP-VAD-CHO is a composite of Ac-VAD-CHO, a non-selective caspase inhibitor, and a cell-permeable hydrophobic sequence derived from K-FGF. Synonyms: Caspase Inhibitor II; Ac-AAVALLPAVLLALLAP-VAD-aldehyde; Ac-AAVALLPAVLLALLAPVAD-CHO. Grades: ≥95%. Molecular formula: C88H151N19O22·xCF3COOH. Mole weight: 1827.3.
Ac-Arg-Glu(EDANS)-Val-His-His-Gln-Lys-Leu-Val-Phe-Lys(DABCYL)-Arg-OH trifluoroacetate salt
Ac-DMQD-CHO is a peptide inhibitor of caspase-3 (IC50 = 39 nM). It is selective for caspase-3 over caspase-1 and caspase-8 (IC50s = 148 and 1,100 nM, respectively). Ac-DMQD-CHO inhibits apoptosis induced by camptothecin in immortalized human T/C 28a4 chondrocytes and primary human chondrocytes. In vivo, Ac-DMQD-CHO (1 mg/kg, i.v.) reduces the number of apoptotic cells, cavitation, and demyelination in a rat model of traumatic injury to the spinal cord. Synonyms: Ac-Asp-Met-Gln-Asp-CHO; Caspase-3 Inhibitor. Grades: ≥95%. Molecular formula: C20H31N5O10S·xCF3COOH. Mole weight: 533.6.
Acetyl β-endorphin is an acetylated derivative of β-endorphin that binds to opioid receptors in rat caudal dorsomedial medulla (Ki = 490 nM) and mouse brain membrane preparations (IC50 = 109 nM). Synonyms: N-acetyl β-endorphin. Grades: ≥95%. Molecular formula: C160H253N39O47S·xCF3COOH. Mole weight: 3507.0.
Acetyl PACAP (1-38) (human, mouse, ovine, porcine, rat) trifluoroacetate salt
Acetyl pituitary adenylate cyclase-activating peptide (PACAP) (1-38) is an N-terminally acetylated form of PACAP (1-38). Synonyms: Acetyl pituitary adenylate cyclase-activating peptide (1-38). Grades: ≥95%. Molecular formula: C205H333N63O54S·xCF3COOH. Mole weight: 4576.29.
Acetyl-(Phe1)-Octreotide trifluoroacetate salt
Acetyl-(Phe1)-Octreotide trifluoroacetate salt is an impurity of octreotide. Synonyms: Ac-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol trifluoroacetate salt (Disulfide bridge: Cys2-Cys7). Molecular formula: C51H68N10O11S2.C2HF3O2. Mole weight: 1175.30.
Ac-IETD-CHO is an inhibitor of caspase-8 (IC50 = 5 nM). It inhibits fluticasone propionate-induced increases in apoptosis in peripheral blood T-cells isolated from patients with asthma when used at a concentration 60 μM. Synonyms: Ac-Ile-Glu-Thr-Asp-CHO; Caspase-8 Inhibitor. Grades: ≥95%. CAS No. 191338-86-0. Molecular formula: C21H34N4O10·xCF3COOH. Mole weight: 502.52.
Ac-LEVD-CHO trifluoroacetate salt
Ac-LEVD-CHO is a caspase-4 inhibitor. It inhibits IL-1α expression and secretion and caspase-4 activation induced by the T. denticola periodontal pathogen surface protein Td92 in human gingival fibroblasts when used at a concentration of 30 μM. Synonyms: Ac-Leu-Glu-Val-Asp-CHO; Caspase-4 Inhibitor I. Grades: ≥95%. CAS No. 402832-01-3. Molecular formula: C22H36N4O9·xCF3COOH. Mole weight: 500.5.
Ac-Lys-(Me)Leu-Val-(Me)Phe-Phe-NH2 trifluoroacetate salt
Ac-RLR-AMC is a fluorogenic substrate for the 26S proteasome. Ac-RLR-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the trypsin-like activity of 26S proteasomes. Synonyms: Ac-Arg-Leu-Arg-7-amino-4-methylcoumarin; (S)-2-acetamido-5-guanidino-N-((S)-1-(((S)-5-guanidino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)pentanamide, 2,2,2-trifluoroacetate salt. Grades: ≥98%. Molecular formula: C30H46N10O6·CF3COOH. Mole weight: 756.8.
ACTH (1-13) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt
ACTH (1-13) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response. Synonyms: SYSMEHFRWGKPV-OH. Grades: ≥98%. Molecular formula: C75H106N20O19S·xCF3COOH. Mole weight: 1623.83.
ACTH (1-17) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt
ACTH (1-17) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response. Synonyms: Adrenocorticotropic hormone (1-17); SYSMEHFRWGKPVGKKR-OH; Cortrophin; Corticotrophin. Grades: ≥98%. Molecular formula: C95H145N29O23S·xCF3COOH. Mole weight: 2093.42.
ACTH (4-10) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt
Adrenocorticotropic hormone (ACTH) (4-10) is an endogenous peptide fragment of ACTH, a peptide hormone produced by the anterior pituitary gland that is involved in the biological stress response. Synonyms: Adrenocorticotropic hormone (4-10); Corticotropin (4-10); H-Met-Glu-His-Phe-Arg-Trp-Gly-OH. Grades: ≥95%. Molecular formula: C44H59N13O10S·xCF3COOH. Mole weight: 962.09.
ACTH (6-24) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt
ACTH (6-24) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response. Synonyms: HFRWGKPVGKKRRPVKVYP; Corticotropin-(6-24)-peptide. Grades: ≥95%. CAS No. 33512-65-1. Molecular formula: C111H175N35O21·xCF3COOH. Mole weight: 2335.8.
(Ala1)-PAR4 (1-6) amide (mouse) trifluoroacetate salt
(Ala1)-PAR4 (1-6) amide (mouse) is a peptide agonist of proteinase-activated receptor 4 (PAR4) that induces aggregation of rat and human platelets in vitro (EC50s = 15 and 60 μM, respectively). Synonyms: AY-NH2; AYPGKF-NH2; H-Ala-Tyr-Pro-Gly-Lys-Phe-NH2; PAR4-AP; Proteinase-Activated Receptor 4 Activating Peptide; L-alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalaninamide trifluoroacetate salt. Grades: ≥95%. Molecular formula: C34H48N8O7·xCF3COOH. Mole weight: 680.79.
(Ala1)-PAR4 (1-6) (mouse) trifluoroacetate salt
(Ala1)-PAR4 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 4 (PAR4) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse PAR4 and residues 60-65 of the full-length sequence with an alanine residue substituted for glycine at position 1/60. Synonyms: H-Ala-Tyr-Pro-Gly-Lys-Phe-OH; L-alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalanine trifluoroacetate salt. Grades: ≥95%. Molecular formula: C34H47N7O8·xCF3COOH. Mole weight: 681.78.
Aldehyde Reactive Probe is a biotinylated-aminooxy form of biotin that can used for the detection and quantification of AP sites in damaged DNA. Synonyms: N-(Aminooxyacetyl)-N'-(D-biotinoyl)hydrazine, trifluoroacetic acid salt; ARP. CAS No. 627090-10-2. Molecular formula: C14H22F3N5O6S. Mole weight: 445.41.
α-CGRP (8-37) (human) trifluoroacetate salt
Calcitonin gene-related protein (CGRP) is a neuropeptide. α-CGRP (8-37) is an antagonist of CGRP receptors. Synonyms: Calcitonin Gene-Related Peptide-1 (8-37) (human); CGRP-1 (8-37) (human); α-Calcitonin Gene-Related Peptide (8-37) (human). Grades: ≥95%. Molecular formula: C139H230N44O38·xCF3COOH. Mole weight: 3125.59.
Amylin (human) (amidated) trifluoroacetate salt
Amylin is a pancreatic β-cell hormone that produces effects in several different organ systems. Amylin is a 37-amino-acid peptide that activates its specific receptors, which are multisubunit G protein and resulting in multiple receptor subtypes. Amylin's major role is as a glucoregulatory hormone, and it is an important regulator of energy metabolism in health and disease. Amidated amylin increases the rate of glycogen synthesis induced by insulin in isolated rat soleus muscle when used at a concentration of 1 nM, while linear non-amidated amylin has no effect. Synonyms: IAPP (human) (amidated); Islet Amyloid Polypeptide (human) (amidated). Grades: ≥95%. Molecular formula: C165H261N51O55S2·xCF3COOH. Mole weight: 3903.28.
Amylin (human) trifluoroacetate salt
Amylin is a pancreatic β-cell hormone that produces effects in several different organ systems. Amylin is a 37-amino-acid peptide that activates its specific receptors, which are multisubunit G protein and resulting in multiple receptor subtypes. Amylin's major role is as a glucoregulatory hormone, and it is an important regulator of energy metabolism in health and disease. Amidated amylin increases the rate of glycogen synthesis induced by insulin in isolated rat soleus muscle when used at a concentration of 1 nM, while linear non-amidated amylin has no effect. Synonyms: IAPP (human); Islet Amyloid Polypeptide (human). Grades: ≥95%. Molecular formula: C165H260N50O56S2·xCF3COOH. Mole weight: 3904.27.
Amylin (rat, mouse) trifluoroacetate salt
Amylin is a pancreatic β-cell hormone that produces effects in several different organ systems. Amylin is a 37-amino-acid peptide that activates its specific receptors, which are multisubunit G protein and resulting in multiple receptor subtypes. Amylin's major role is as a glucoregulatory hormone, and it is an important regulator of energy metabolism in health and disease. Amidated amylin increases the rate of glycogen synthesis induced by insulin in isolated rat soleus muscle when used at a concentration of 1 nM, while linear non-amidated amylin has no effect. Synonyms: IAPP (rat, mouse); Islet Amyloid Polypeptide (rat, mouse). Grades: ≥95%. Molecular formula: C167H272N52O53S2·xCF3COOH. Mole weight: 3920.40.
Amyloid ?-Protein Fragment 1-40 amide trifluoroacetate salt
Angiotensin I (human, rat, mouse) trifluoroacetate salt
Angiotensin I is formed from angiotensinogen by the action of renin, which is released from the kidney juxtaglomerular cells. Angiotensin I is further cleaved to angiotensin II by angiotensin converting enzyme. Angiotensin is a protein hormone that causes blood vessels to become narrower. It helps to maintain blood pressure and fluid balance in the body. It binds to angiotensin receptors in human myometrium membrane preparations with Kd of 11.2 nM and increases renal vascular resistance in isolated rat kidney with EC50 of 10.5 nM. Grades: ≥95%. Molecular formula: C62H89N17O14·xCF3COOH. Mole weight: 1296.48.
APC 366 is a mast cell tryptase inhibitor with Ki of 7.1 μM for human recombinant enzyme. It is a selective inhibitor of mast cell tryptase, which has been shown to inhibit antigen-induced early asthmatic response (EAR), late asthmatic response (LAR), and bronchial hyperresponsiveness (BHR) in a sheep model of allergic asthma. APC 366 can reduce maximum contractile response to histamine in isolated bronchial tissue from ovalbumin-sensitized guinea pigs. It can also reduce airway resistance and increases dynamic lung compliance in A. suum antigen-challenged pigs. Grades: ≥95%. Molecular formula: C22H28N6O4·xCF3COOH. Mole weight: 440.50.
Apelin-13 trifluoroacetate salt is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM. Synonyms: Apelin-13 triTFA. Molecular formula: C75H114F9N23O22S. Mole weight: 1892.89.
Arginine vasotocin trifluoroacetate salt
Arginine vasotocin (AVT) is the non-mammalian homolog of arginine vasopressin (AVP) and serves as an important modulator of social behavior in addition to its peripheral functions related to osmoregulation, reproductive physiology, and stress hormone release. AVT is aslo homologous to arginine vasopressin in mammals and is endogenously released from the neurohypophysis primarily in response to hyperosmotic stimuli and associated cellular dehydration. Arginine vasotocin is a nonapeptide hormone agonist of the AVT receptor with EC50 of 13 nM for eliciting membrane. Synonyms: [Arg8]-Vasotocin; AVT. Grades: ≥95%. Molecular formula: C43H67N15O12S2·xCF3COOH. Mole weight: 1050.22.
[Asn670, Leu671]-Amyloid ?/A4 Precursor Protein 770 Fragment 667-676 trifluoroacetate salt
(Aspartimide15)-Glucagon trifluoroacetate salt is an impurity of glucagon. Synonyms: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Aspartimide-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH. Molecular formula: C153H223N43O48S.C2HF3O2. Mole weight: 3578.75.
(Aspartimide21)-Glucagon trifluoroacetate salt
(Aspartimide21)-Glucagon trifluoroacetate salt is an impurity of glucagon. Synonyms: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Aspartimide-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH. Molecular formula: C153H223N43O48S.C2HF3O2. Mole weight: 3578.75.
Astressin2b trifluoroacetate salt
Astressin2b trifluoroacetate salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Astressin 2B. Product Category: Heterocyclic Organic Compound. CAS No. 681260-70-8. Molecular formula: C183H307N49O53??·xC2HF3O2. Mole weight: 4041.69 (free base b. Purity: 0.96. IUPACName: Astressin2B trifluoroacetate salt. Canonical SMILES: CCCCC(C(=O)NC(C(C)CC)C(=O)NC(CCC(=O)O)C(=O)NC(C(C)CC)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(C)C(=O)NC1CCC(=O)NCCCCC(NC(=O)C(NC(=O)C(NC1=O)CC(=O)N)CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(C)(CC(C)C)C(=O)NC(C(C)CC)C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(C)(CC(C)C)NC(=O)C(CC2=CNC=N2)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C. Product ID: ACM681260708. Alfa Chemistry ISO 9001:2015 Certified.
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