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| Product | Description | |
|---|---|---|
| (2-(1,3-Dithiolan-2-yl)-Trp25)-Liraglutide trifluoroacetate salt | (2-(1,3-Dithiolan-2-yl)-Trp25)-Liraglutide trifluoroacetate salt is an impurity of Liraglutide. Synonyms: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-2-(1,3-dithiolan-2-yl)-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH trifluoroacetate salt. Molecular formula: C175H269N43O51S2.C2HF3O2. Mole weight: 3969.41. |  |
| (2-(2-Trifluoromethyl-1,3-dithiolan-2-yl)-Trp25)-Liraglutide trifluoroacetate salt | (2-(2-Trifluoromethyl-1,3-dithiolan-2-yl)-Trp25)-Liraglutide trifluoroacetate salt is an impurity of Liraglutide. Synonyms: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-2-(2-trifluoromethyl-1,3-dithiolan-2-yl)-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH trifluoroacetate salt. Molecular formula: C176H268F3N43O51S2.C2HF3O2. Mole weight: 4037.41. | |
| 2-Furoyl-LIGRLO amide trifluoroacetate salt | 2-Furoyl-LIGRLO amide is a potent and selective agonist of the proteinase-activated receptor, PAR2 (pD2 = 7.0). Grades: ≥95%. Molecular formula: C36H63N11O8·xCF3COOH. Mole weight: 777.9. | |
| (2-Hydroxy-Trp25)-Liraglutide trifluoroacetate salt | (2-Hydroxy-Trp25)-Liraglutide trifluoroacetate salt is an impurity of Liraglutide. Synonyms: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-2-hydroxy-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C172H265N43O52.C2HF3O2. Mole weight: 3881.21. | |
| (2R)-2-Amino-4-methyl-1-[(2R)-2-methyloxiran-2-yl]pentan-1-one Trifluoroacetate Salt | (2R)-2-Amino-4-methyl-1-(2-methyloxiran-2-yl)pentan-1-one Trifluoroacetate Salt s an impurity of carfilzomib (C183460). Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C11H18F3NO4, Molecular Weight: 285.26. US Biological Life Sciences. |  Worldwide |
| (2S,4R)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate Trifluoroacetate Salt | (2S,4R)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate Trifluoroacetate Salt is an intermediate in synthesizing Carfilzomib (2S,4R)-Diol (C183500), a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C11H21NO4; (C2HF3O2), Molecular Weight: 231.2911402. US Biological Life Sciences. | Worldwide |
| 6 TM1a trifluoroacetate salt | Heterocyclic Organic Compound. Alternative Names: LGLLVAIV trifluoroacetate salt, |A6 TM1a trifluoroacetate salt, Leu-Gly-Leu-Leu-Val-Ala-Ile-Val trifluoroacetate salt, 1163243-88-6. CAS No. 1163243-88-6. Molecular formula: C41H73F3N8O11. Mole weight: 797.04 (free base basis). Purity: 0.96. IUPACName: (2S) -2- [2- [ (2S, 3S) -1- [ [ (2R) -1- [ [ (2S) -1- [ [ (4S, 7S) -7- [ [2- [ [ (2S) -2-amino-4-methylpentanoyl] amino] acetyl] amino] -2, 9-dimethyl-5, 6-dioxodecan-4-yl] amino] -3-methyl-1-oxobutan-2-yl] amino] -1-oxopropan-2-yl] amino] -3-methyl-1-oxopentan-2-yl] hydrazinyl] -3-methylbutan. Canonical SMILES: CCC (C)C (C (=O)NC (C)C (=O)NC (C (C)C)C (=O)NC (CC (C)C)C (=O)C (=O)C (CC (C)C)NC (=O)CNC (=O)C (CC (C)C)N)NNC (C (C)C)C (=O)O. C (=O) (C (F) (F)F)O. Catalog: ACM1163243886. |  |
| AAF-CMK trifluoroacetate salt | AAF-CMK is a serine protease inhibitor which irreversibly inhibits TPPII (tripeptidyl peptidase II), a giant protease which may substitute for some proteasome function, and reversibly inhibits Cln2 (TPPI). Synonyms: N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase Inhibitor II; L-Alaninamide,L-alanyl-N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-. Grades: ≥95%. CAS No. 184901-82-4. Molecular formula: C18H23ClF3N3O5. Mole weight: 453.84. | |
| Abz-LFK(Dnp)-OH trifluoroacetate salt | Abz-LFK(Dnp)-OH trifluoroacetate salt is an angiotensin-converting enzyme (ACE) fluorescent peptide substrate that binds specifically to the C domain of ACE. It has been used to investigate the development of novel antibacterial calixarene derivatives, as well as the efficacy and toxicity of antimicrobial peptide M33 as a possible antimicrobial agent for lung infections and sepsis. Synonyms: O-Aminobenzoic acid-Leu-Phe-Lys(DNP)-OH trifluoroacetate salt; Abz-Leu-Phe-Lys-DNP trifluoroacetate salt; (2-aminobenzoyl)-L-leucyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine trifluoroacetic acid; N-(2-Aminobenzoyl)-L-leucyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine trifluoroacetate (1:1); L-Lysine, N-(2-aminobenzoyl)-L-leucyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-, compd. with 2,2,2-trifluoroacetic acid (1:1); (2S)-2-[[(2S)-2-([(2S)-2-[(2-Aminobenzoyl)amino]-4-methylpentanoyl]amino)-3-phenylpropanoyl]amino]-6-(2,4-dinitroanilino)hexanoic acid trifluoroacetate. Grades: ≥97% by HPLC. CAS No. 1217437-31-4. Molecular formula: C34H41N7O9.C2HF3O2. Mole weight: 805.76. | |
| Ac-AAVALLPAVLLALLAP-DEVD-CHO trifluoroacetate salt | Ac-AAVALLPAVLLALLAP-DEVD-CHO is a composite of Ac-DEVD-CHO, a peptide inhibitor of caspase-3 and -7, and a cell-permeable hydrophobic sequence derived from K-FGF. Synonyms: Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Glu-Val-Asp-CHO; Ac-AAVALLPAVLLALLAP-DEVD-aldehyde; Ac-AAVALLPAVLLALLAPDEVD-CHO; ?Caspase-3 Inhibitor I; DEVD-CHO-CPP 32. Grades: ≥95%. Molecular formula: C94H158N20O27·xCF3COOH. Mole weight: 2000.42. | |
| Ac-AAVALLPAVLLALLAP-IETD-CHO trifluoroacetate salt | Ac-AAVALLPAVLLALLAP-IETD-CHO is a composite of Ac-IETD-CHO, a peptide inhibitor of caspase-8, and a cell-permeable hydrophobic sequence derived from K-FGF. Synonyms: Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-CHO; Caspase-8 Inhibitor I. Grades: ≥95%. Molecular formula: C95H162N20O26·xCF3COOH. Mole weight: 2000.40. | |
| Ac-AAVALLPAVLLALLAP-VAD-CHO trifluoroacetate salt | Ac-AAVALLPAVLLALLAP-VAD-CHO is a composite of Ac-VAD-CHO, a non-selective caspase inhibitor, and a cell-permeable hydrophobic sequence derived from K-FGF. Synonyms: Caspase Inhibitor II; Ac-AAVALLPAVLLALLAP-VAD-aldehyde; Ac-AAVALLPAVLLALLAPVAD-CHO. Grades: ≥95%. Molecular formula: C88H151N19O22·xCF3COOH. Mole weight: 1827.3. | |
| Ac-DMQD-CHO trifluoroacetate salt | Ac-DMQD-CHO is a peptide inhibitor of caspase-3 (IC50 = 39 nM). It is selective for caspase-3 over caspase-1 and caspase-8 (IC50s = 148 and 1,100 nM, respectively). Ac-DMQD-CHO inhibits apoptosis induced by camptothecin in immortalized human T/C 28a4 chondrocytes and primary human chondrocytes. In vivo, Ac-DMQD-CHO (1 mg/kg, i.v.) reduces the number of apoptotic cells, cavitation, and demyelination in a rat model of traumatic injury to the spinal cord. Synonyms: Ac-Asp-Met-Gln-Asp-CHO; Caspase-3 Inhibitor. Grades: ≥95%. Molecular formula: C20H31N5O10S·xCF3COOH. Mole weight: 533.6. | |
| Acetyl β-Endorphin (human) trifluoroacetate salt | Acetyl β-endorphin is an acetylated derivative of β-endorphin that binds to opioid receptors in rat caudal dorsomedial medulla (Ki = 490 nM) and mouse brain membrane preparations (IC50 = 109 nM). Synonyms: N-acetyl β-endorphin. Grades: ≥95%. Molecular formula: C160H253N39O47S·xCF3COOH. Mole weight: 3507.0. | |
| Acetyl PACAP (1-38) (human, mouse, ovine, porcine, rat) trifluoroacetate salt | Acetyl pituitary adenylate cyclase-activating peptide (PACAP) (1-38) is an N-terminally acetylated form of PACAP (1-38). Synonyms: Acetyl pituitary adenylate cyclase-activating peptide (1-38). Grades: ≥95%. Molecular formula: C205H333N63O54S·xCF3COOH. Mole weight: 4576.29. | |
| Acetyl-(Phe1)-Octreotide trifluoroacetate salt | Acetyl-(Phe1)-Octreotide trifluoroacetate salt is an impurity of octreotide. Synonyms: Ac-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol trifluoroacetate salt (Disulfide bridge: Cys2-Cys7). Molecular formula: C51H68N10O11S2.C2HF3O2. Mole weight: 1175.30. | |
| Ac-IETD-CHO trifluoroacetate salt | Ac-IETD-CHO is an inhibitor of caspase-8 (IC50 = 5 nM). It inhibits fluticasone propionate-induced increases in apoptosis in peripheral blood T-cells isolated from patients with asthma when used at a concentration 60 μM. Synonyms: Ac-Ile-Glu-Thr-Asp-CHO; Caspase-8 Inhibitor. Grades: ≥95%. CAS No. 191338-86-0. Molecular formula: C21H34N4O10·xCF3COOH. Mole weight: 502.52. | |
| Ac-LEVD-CHO trifluoroacetate salt | Ac-LEVD-CHO is a caspase-4 inhibitor. It inhibits IL-1α expression and secretion and caspase-4 activation induced by the T. denticola periodontal pathogen surface protein Td92 in human gingival fibroblasts when used at a concentration of 30 μM. Synonyms: Ac-Leu-Glu-Val-Asp-CHO; Caspase-4 Inhibitor I. Grades: ≥95%. CAS No. 402832-01-3. Molecular formula: C22H36N4O9·xCF3COOH. Mole weight: 500.5. | |
| Ac-RLR-AMC trifluoroacetate salt | Ac-RLR-AMC is a fluorogenic substrate for the 26S proteasome. Ac-RLR-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the trypsin-like activity of 26S proteasomes. Synonyms: Ac-Arg-Leu-Arg-7-amino-4-methylcoumarin; (S)-2-acetamido-5-guanidino-N-((S)-1-(((S)-5-guanidino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)pentanamide, 2,2,2-trifluoroacetate salt. Grades: ≥98%. Molecular formula: C30H46N10O6·CF3COOH. Mole weight: 756.8. | |
| ACTH (1-13) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt | ACTH (1-13) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response. Synonyms: SYSMEHFRWGKPV-OH. Grades: ≥98%. Molecular formula: C75H106N20O19S·xCF3COOH. Mole weight: 1623.83. | |
| ACTH (1-17) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt | ACTH (1-17) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response. Synonyms: Adrenocorticotropic hormone (1-17); SYSMEHFRWGKPVGKKR-OH; Cortrophin; Corticotrophin. Grades: ≥98%. Molecular formula: C95H145N29O23S·xCF3COOH. Mole weight: 2093.42. | |
| ACTH (4-10) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt | Adrenocorticotropic hormone (ACTH) (4-10) is an endogenous peptide fragment of ACTH, a peptide hormone produced by the anterior pituitary gland that is involved in the biological stress response. Synonyms: Adrenocorticotropic hormone (4-10); Corticotropin (4-10); H-Met-Glu-His-Phe-Arg-Trp-Gly-OH. Grades: ≥95%. Molecular formula: C44H59N13O10S·xCF3COOH. Mole weight: 962.09. | |
| ACTH (6-24) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt | ACTH (6-24) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response. Synonyms: HFRWGKPVGKKRRPVKVYP; Corticotropin-(6-24)-peptide. Grades: ≥95%. CAS No. 33512-65-1. Molecular formula: C111H175N35O21·xCF3COOH. Mole weight: 2335.8. | |
| Ac-VDVAD-CHO trifluoroacetate salt | Cas No. 194022-51-0. | |
| Ac-VEID-CHO trifluoroacetate salt | Cas No. 319494-39-8. | |
| (Ala1)-PAR4 (1-6) amide (mouse) trifluoroacetate salt | (Ala1)-PAR4 (1-6) amide (mouse) is a peptide agonist of proteinase-activated receptor 4 (PAR4) that induces aggregation of rat and human platelets in vitro (EC50s = 15 and 60 μM, respectively). Synonyms: AY-NH2; AYPGKF-NH2; H-Ala-Tyr-Pro-Gly-Lys-Phe-NH2; PAR4-AP; Proteinase-Activated Receptor 4 Activating Peptide; L-alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalaninamide trifluoroacetate salt. Grades: ≥95%. Molecular formula: C34H48N8O7·xCF3COOH. Mole weight: 680.79. | |
| (Ala1)-PAR4 (1-6) (mouse) trifluoroacetate salt | (Ala1)-PAR4 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 4 (PAR4) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse PAR4 and residues 60-65 of the full-length sequence with an alanine residue substituted for glycine at position 1/60. Synonyms: H-Ala-Tyr-Pro-Gly-Lys-Phe-OH; L-alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalanine trifluoroacetate salt. Grades: ≥95%. Molecular formula: C34H47N7O8·xCF3COOH. Mole weight: 681.78. | |
| Aldehyde Reactive Probe (trifluoroacetate salt) | Aldehyde Reactive Probe is a biotinylated-aminooxy form of biotin that can used for the detection and quantification of AP sites in damaged DNA. Synonyms: N-(Aminooxyacetyl)-N'-(D-biotinoyl)hydrazine, trifluoroacetic acid salt; ARP. CAS No. 627090-10-2. Molecular formula: C14H22F3N5O6S. Mole weight: 445.41. | |
| α-CGRP (8-37) (human) trifluoroacetate salt | Calcitonin gene-related protein (CGRP) is a neuropeptide. α-CGRP (8-37) is an antagonist of CGRP receptors. Synonyms: Calcitonin Gene-Related Peptide-1 (8-37) (human); CGRP-1 (8-37) (human); α-Calcitonin Gene-Related Peptide (8-37) (human). Grades: ≥95%. Molecular formula: C139H230N44O38·xCF3COOH. Mole weight: 3125.59. | |
| Amylin (human) (amidated) trifluoroacetate salt | Amylin is a pancreatic β-cell hormone that produces effects in several different organ systems. Amylin is a 37-amino-acid peptide that activates its specific receptors, which are multisubunit G protein and resulting in multiple receptor subtypes. Amylin's major role is as a glucoregulatory hormone, and it is an important regulator of energy metabolism in health and disease. Amidated amylin increases the rate of glycogen synthesis induced by insulin in isolated rat soleus muscle when used at a concentration of 1 nM, while linear non-amidated amylin has no effect. Synonyms: IAPP (human) (amidated); Islet Amyloid Polypeptide (human) (amidated). Grades: ≥95%. Molecular formula: C165H261N51O55S2·xCF3COOH. Mole weight: 3903.28. | |
| Amylin (human) trifluoroacetate salt | Amylin is a pancreatic β-cell hormone that produces effects in several different organ systems. Amylin is a 37-amino-acid peptide that activates its specific receptors, which are multisubunit G protein and resulting in multiple receptor subtypes. Amylin's major role is as a glucoregulatory hormone, and it is an important regulator of energy metabolism in health and disease. Amidated amylin increases the rate of glycogen synthesis induced by insulin in isolated rat soleus muscle when used at a concentration of 1 nM, while linear non-amidated amylin has no effect. Synonyms: IAPP (human); Islet Amyloid Polypeptide (human). Grades: ≥95%. Molecular formula: C165H260N50O56S2·xCF3COOH. Mole weight: 3904.27. | |
| Amylin (rat, mouse) trifluoroacetate salt | Amylin is a pancreatic β-cell hormone that produces effects in several different organ systems. Amylin is a 37-amino-acid peptide that activates its specific receptors, which are multisubunit G protein and resulting in multiple receptor subtypes. Amylin's major role is as a glucoregulatory hormone, and it is an important regulator of energy metabolism in health and disease. Amidated amylin increases the rate of glycogen synthesis induced by insulin in isolated rat soleus muscle when used at a concentration of 1 nM, while linear non-amidated amylin has no effect. Synonyms: IAPP (rat, mouse); Islet Amyloid Polypeptide (rat, mouse). Grades: ≥95%. Molecular formula: C167H272N52O53S2·xCF3COOH. Mole weight: 3920.40. | |
| Angiotensin I (human, rat, mouse) trifluoroacetate salt | Angiotensin I is formed from angiotensinogen by the action of renin, which is released from the kidney juxtaglomerular cells. Angiotensin I is further cleaved to angiotensin II by angiotensin converting enzyme. Angiotensin is a protein hormone that causes blood vessels to become narrower. It helps to maintain blood pressure and fluid balance in the body. It binds to angiotensin receptors in human myometrium membrane preparations with Kd of 11.2 nM and increases renal vascular resistance in isolated rat kidney with EC50 of 10.5 nM. Grades: ≥95%. Molecular formula: C62H89N17O14·xCF3COOH. Mole weight: 1296.48. | |
| APC 366 trifluoroacetate salt | APC 366 is a mast cell tryptase inhibitor with Ki of 7.1 μM for human recombinant enzyme. It is a selective inhibitor of mast cell tryptase, which has been shown to inhibit antigen-induced early asthmatic response (EAR), late asthmatic response (LAR), and bronchial hyperresponsiveness (BHR) in a sheep model of allergic asthma. APC 366 can reduce maximum contractile response to histamine in isolated bronchial tissue from ovalbumin-sensitized guinea pigs. It can also reduce airway resistance and increases dynamic lung compliance in A. suum antigen-challenged pigs. Grades: ≥95%. Molecular formula: C22H28N6O4·xCF3COOH. Mole weight: 440.50. | |
| Apelin-13 trifluoroacetate salt | Apelin-13 trifluoroacetate salt is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM. Synonyms: Apelin-13 triTFA. Molecular formula: C75H114F9N23O22S. Mole weight: 1892.89. | |
| Arginine vasotocin trifluoroacetate salt | Arginine vasotocin (AVT) is the non-mammalian homolog of arginine vasopressin (AVP) and serves as an important modulator of social behavior in addition to its peripheral functions related to osmoregulation, reproductive physiology, and stress hormone release. AVT is aslo homologous to arginine vasopressin in mammals and is endogenously released from the neurohypophysis primarily in response to hyperosmotic stimuli and associated cellular dehydration. Arginine vasotocin is a nonapeptide hormone agonist of the AVT receptor with EC50 of 13 nM for eliciting membrane. Synonyms: [Arg8]-Vasotocin; AVT. Grades: ≥95%. Molecular formula: C43H67N15O12S2·xCF3COOH. Mole weight: 1050.22. | |
| (Aspartimide15)-Glucagon trifluoroacetate salt | (Aspartimide15)-Glucagon trifluoroacetate salt is an impurity of glucagon. Synonyms: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Aspartimide-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH. Molecular formula: C153H223N43O48S.C2HF3O2. Mole weight: 3578.75. | |
| (Aspartimide21)-Glucagon trifluoroacetate salt | (Aspartimide21)-Glucagon trifluoroacetate salt is an impurity of glucagon. Synonyms: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Aspartimide-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH. Molecular formula: C153H223N43O48S.C2HF3O2. Mole weight: 3578.75. | |
| ATN-161 trifluoroacetate salt | ATN-161 trifluoroacetate salt is a beta integrin antagonist with antitumor activity. It is a five -amino-acid peptide derived from the synergy region of fibronectin. It inhibited VEGF-induced migration and capillary tube formation in hCECs, but did not inhibit proliferation. Synonyms: ATN-161 TFA salt; ATN 161 TFA salt; ATN161 TFA salt. Grades: >98%. CAS No. 904763-27-5. Molecular formula: C25H36F3N9O10S. Mole weight: 711.67. | |
| b-Alanine 7-amido-4-methylcoumarin trifluoroacetate salt | Synonyms: H-Beta-Ala-AMC TFA; Beta-Alanine 7-Amido-4-Methylcoumarin Trifluoroacetate Salt; H-Beta-Ala-AMC (TFA). Grades: ≥ 98% (HPLC). CAS No. 201847-54-3. Molecular formula: C15H15F3N2O5. Mole weight: 360.29. | |
| (β-Ala29)-Glucagon trifluoroacetate salt | (β-Ala29)-Glucagon trifluoroacetate salt is an impurity of glucagon. Synonyms: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-β-Ala-OH. Molecular formula: C152H223N43O48S.C2HF3O2. Mole weight: 3566.74. | |
| β-CGRP (human) trifluoroacetate salt | β-Calcitonin gene-related peptide (β-CGRP) is a neuropeptide that binds selectively to a heteromeric complex of calcitonin receptor-like receptor (CRLR) and receptor activity-modifying protein 1 (RAMP1). Synonyms: Calcitonin Gene-Related Peptide-2 (human); β-Calcitonin Gene-Related Peptide (human); CGRP-2 (human). Grades: ≥95%. Molecular formula: C162H267N51O48S3·xCF3COOH. Mole weight: 3793.37. | |
| β-Endorphin (1-26) (human) trifluoroacetate salt | β-endorphin (1-26) is a neuropeptide found in rat hippocampus, brain stem, and pituitary. It is an opioid receptor agonist that inhibits potassium-induced norepinephrine (NE) release in rat cortical slices (IC50 = 2.5 nM). Grades: ≥95%. Molecular formula: C130H208N32O38S·xCF3COOH. Mole weight: 2859.3. | |
| β-Endorphin (1-27) (human) trifluoroacetate salt | β-Endorphin (1-27) is an endogenous peptide that binds to μ-, δ-, and κ-opioid receptors (Kis = 5.31, 6.17, and 39.82 nM, respectively, in COS-1 cells expressing rat receptors). It is an antagonist of β-endorphin analgesia. Grades: ≥95%. Molecular formula: C139H217N33O40S·xCF3COOH. Mole weight: 3022.47. | |
| BMS 345541 trifluoroacetate salt | BMS 345541 is a cell-permeable inhibitor of the IκB kinases IKKα with IC50s of 4 uM and IKKβ with IC50s of 0.3 μM, which binds at allosteric site of the enzyme and displays ~10-fold greater selectivity at IKK-2 over IKK-1. It exhibits no effect against a panel of 15 other kinases. BMS 345541 is used to explore novel roles for IKK phosphorylation and NF-κB signaling. Synonyms: IKK Inhibitor III. Grades: ≥98%. CAS No. 547757-23-3. Molecular formula: C14H17N5·2CF3COOH. Mole weight: 483.4. | |
| Boc-AEVD-CHO trifluoroacetate salt | Boc-AEVD-CHO is an inhibitor of caspase-8 (Ki = 1.6 nM) that also inhibits caspase-1, -3, -6, and -9 (Kis = <12, 42, 52, and 48 nM, respectively). It inhibits apoptosis induced by the aneugen nocodazole in isolated human peripheral blood mononuclear cells (PBMCs) at concentration of 300 μM. Synonyms: Boc-Ala-Glu-Val-Asp-CHO. Grades: ≥95%. Molecular formula: C22H36N4O10·xCF3COOH. Mole weight: 516.54. | |
| Brain Natriuretic Peptide (1-32) (human) trifluoroacetate salt | Brain natriuretic peptide (BNP) (1-32) is an endogenous peptide that has cardiovascular functions and belongs to the family of natriuretic peptides. It is an agonist of natriuretic peptide receptors (NPRs) 1 and 3 with Kd values of 7.3 and 13 pM, respectively. It also binds to human recombinant NPR1 and NPR3 with IC50 values of 8 and 2.6 nM, respectively. It also relaxes contractions induced by prostaglandin F2α (PGF2α) in isolated porcine coronary artery and rat aortic strips (IC50s = 0.02 and 12.1 nM, respectively). Synonyms: BNP (1-32) (human). Grades: ≥95%. Molecular formula: C143H244N50O42S4·xCF3COOH. Mole weight: 3464.04. | |
| Buserelin-NHNH2 trifluoroacetate salt | Buserelin, sold under the brand name Suprefact among others, is a medication which is used primarily in the treatment of prostate cancer and endometriosis. Buserelin is a synthetic gonadotropin-releasing hormone (GNRH) agonist that is at least 20 times more potent than GNRH. It is a long-acting agent that, after an initial increase in sex hormone levels by about 95% in both sexes, decreases the level of circulating gonadotropins and sex hormones. Buserelin can reduce tumor growth in a DMBA-induced rat model of mammary cancer. The medication is one of only two medically used GnRH analogues that are available as nasal sprays, the other being nafarelin. Buserelin is available as a generic medication. Grades: ≥95%. Molecular formula: C58H83N17O13·xCF3COOH. Mole weight: 1226.39. | |
| Calcitonin (salmon) trifluoroacetate salt | Calcitonin is a peptide hormone that lowers blood calcium levels and inhibits bone resorption. The binding of salmon calcitonin to the human calcitonin receptor (CTR) is not modulated by receptor activity-modifying proteins (RAMPs), which influences affinity of human calcitonin to CTR. Salmon calcitonin binds to human CTR2 with IC50 values of 0.933, 0.224, 0.134, and 0.317 nM alone and with RAMP1, 2, or 3, respectively. Formulations containing salmon calcitonin have been used to treat hypercalcemia, bone destruction by osteoporosis, and Paget's disease. Synonyms: H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2.TFA (Disulfide bond between Cys1 and Cys7); L-cysteinyl-L-seryl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycyl-L-seryl-glycyl-L-threonyl-L-prolinamide (1->7)-disulfide trifluoroacetate salt; Salmon Calcitonin trifluoroacetate (salt). Grades: ≥95%. CAS No. 171052-37-2. Molecular formula: C145H240N44O48S2.xC2HF3O2. Mole weight: 3431.86 (free base). | |
| Calmodulin-Dependent Protein Kinase II (290-309) trifluoroacetate salt | Calmodulin-dependent protein kinase II (290-309) is a synthetic peptide derived from the rat brain protein sequence that contains the calmodulin binding domain. It inhibits calcium/calmodulin-dependent protein kinase II (CaMKII) with an IC50 value of 52 nM and CaMKII-dependent phosphodiesterase activity with IC50 of 1.1 nM. Calmodulin-dependent protein kinase II (290-309) has been used in the study of CaM binding, autophosphorylation, and dynamics. Grades: ≥95%. Molecular formula: C103H185N31O24S·xCF3COOH. Mole weight: 2273.83. | |
| CALP1 trifluoroacetate salt | CALP1 is an 8-residue calcium-like peptide that interacts with an EF hand motif based on the troponin C superfamily calcium binding site. CALP1 is also a cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site. CALP1 inhibits Ca2+-mediated cytotoxicity and apoptosis with IC50 of 52 μM and activates phosphodiesterase in the presence of calmodulin and absence of calcium. It also decreases radical production induced by phorbol 12-myristate 13-acetate in broncho-alveolar lavage cells. Synonyms: Calcium-like peptide 1. Grades: ≥95%. Molecular formula: C40H75N9O10·xCF3COOH. Mole weight: 842.08. | |
| CALP3 trifluoroacetate salt | CALP3 is a calcium-like peptide that contains the first eight residues of CALP2, which is a 12-residue peptide that interacts with EF hand motif 4 in human calmodulin to activate it in the absence of calcium. It acts as a cell-permeable inhibitor of calcium influx through glutamate receptor channels in cultured rat neocortical neurons with IC50 of 37.25 μM. It also inhibits excitatory cytotoxicity with IC50 of 50.97 μM and apoptosis with IC50 of 33.41 μM. CALP3 was used to study as a new type of Ca2+ channel blocker that targets Ca2+ sensors and prevents Ca2+-mediated apoptosis. Synonyms: H-Val-Lys-Phe-Gly-Val-Gly-Phe-Lys-OH.TFA; L-valyl-L-lysyl-L-phenylalanyl-glycyl-L-valyl-glycyl-L-phenylalanyl-L-lysine trifluoroacetate; CALP 3 trifluoroacetate; CALP-3 trifluoroacetate; CALP3 TFA; CALP 3 TFA; CALP-3 TFA; Calcium-like peptide 3 TFA. Grades: ≥98%. Molecular formula: C46H69F3N10O11. Mole weight: 995.11. | |
| CAY10729 trifluoroacetate salt | Peptidyl Arginine Deiminases (PADs) perform post-translational deiminations of proteins. PADs are calcium-dependent enzymes that catalyze the conversion of L-arginine residues to L-citrulline. CAY10729 is a tetrazole derivative of the PAD inhibitor Cl-amidine that selectively inhibits PAD1 over PAD2, PAD3, and PAD4 (kinact/KI = 162,200, 60,000, 17,500, and 25,400 M-1min-1 for PAD1-4, respectively). Synonyms: CAY 10729; CAY-10729. Grades: ≥70%. Molecular formula: C19H26ClN7O3·xCF3COOH. Mole weight: 435.91. | |
| Charybdotoxin trifluoroacetate salt | Charybdotoxin is a specific inhibitor of the big conductance Ca2+-activated K+ channel which is originally isolated from the scorpion L. quinquestriatus. It blocks large-conductance Ca2+-activated K+ channels (BKCas) in GH3 rat pituitary tumor cells and primary bovine aortic smooth muscle cells (Kds = 2.1 and ~2.1 nM, respectively). Synonyms: ChTX. Grades: ≥95%. Molecular formula: C176H277N57O55S7·xCF3COOH. Mole weight: 4295.90. | |
| cis-3-Fluorocyclopentanamine trifluoroacetate salt | cis-3-Fluorocyclopentanamine trifluoroacetate salt. Group: Biochemicals. Alternative Names: (1R,3S)-rel-3-fluorocyclopentanamine trifluoroacetate. Grades: Highly Purified. CAS No. 1154870-58-2. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C7H11F4NO2. US Biological Life Sciences. | Worldwide |
| cis-3-Fluorocyclopentanamine trifluoroacetate salt | Heterocyclic Organic Compound. Alternative Names: (1R,3S)-rel-3-Fluorocyclopentanamine Trifluoroacetate. CAS No. 1154870-58-2. Molecular formula: C7H11F4NO2. Mole weight: 217.16. Purity: 0.96. IUPACName: (1R,3S)-3-fluorocyclopentan-1-amine;2,2,2-trifluoroacetic acid. Canonical SMILES: C1CC(CC1N)F.C(=O)(C(F)(F)F)O. Catalog: ACM1154870582. | |
| Cortistatin-14 trifluoroacetate salt | Cortistatin-14 (TFA) is a neuropeptide which is structural similar to somatostatin-14 and it binds and exerts its function via the somatostatin receptors (sst1-sst5). Cortistatin-14 (TFA) shows anticonvulsive, neuroprotective effect and remarkable anti-inflammatory properties. Cortistatin-14 is an endogenous neuropeptide agonist of somatostatin receptors (IC50s = 0.5-18.2 nM for human SST1-SST5 receptors expressed in CCL39 cells). Grades: ≥95%. Molecular formula: C81H113N19O19S2·xCF3COOH. Mole weight: 1721.01. | |
| CTAP trifluoroacetate salt | CTAP is a water-soluble and selective antagonist of the μ opioid receptor (IC50 = 3.5 nM) over the δ receptor (IC50 = 4,500 nM). It is a cyclic octapeptide which acts as a poor antagonist of the somatostatin receptor (IC50 = 14.3 μM). CTAP is at least 10-fold more potent than naltrexone. Molecular formula: C51H69N13O11S2·xCF3COOH. Mole weight: 1104.31. | |
| CTOP trifluoroacetate salt | CTOP is a peptide that acts as a selective antagonist of the μ-opioid receptor (IC50 = 2.8 nM). CTOP inhibits the antinociceptive effect of morphine in the tail flick test in mice (ED50 = 0.018 nmol) and reverses morphine-induced increases in locomotor activity (ED50 = 0.02 nmol). Synonyms: Phe-Cys-Tyr-Trp-Orn-Thr-Pen-Thr; D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-ornithyl-L-threonyl-3-mercapto-L-valyl-L-threoninamide-cyclic (2?7)-disulfide trifluoroacetate salt. Grades: ≥98%. Molecular formula: C50H67N11O11S2·xCF3COOH. Mole weight: 1062.3 (free base). | |
| C-Type Natriuretic Peptide-22 (human, porcine, rat) trifluoroacetate salt | C-Type natriuretic peptide-22 is an endogenous peptide which has diverse biological activities. CNP-22 acts as a selective agonist of natriuretic peptide receptors (NPRs) 2 and 3 (Kds = 7, 10.8, and >500,000 pM for NPR2, 3, and 1, respectively). The 22 amino acid sequence corresponds to residues 105-126 of its precursors prepro CNP, pro CNP, and CNP-53. Synonyms: CNP-22; glycyl-L-leucyl-L-seryl-L-lysylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-leucyl-L-lysyl-L-leucyl-L-α-aspartyl-L-arginyl-L-isoleucylglycyl-L-seryl-L-methionyl-L-serylglycyl-L-leucylglycyl-L-cysteine cyclic (6?22)-disulfide trifluoroacetate salt. Grades: ≥95%. Molecular formula: C93H157N27O28S3·xCF3COOH. Mole weight: 2197.60. | |
| (D-Ala18)-Liraglutide trifluoroacetate salt | (D-Ala18)-Liraglutide trifluoroacetate salt is an impurity of Liraglutide. Synonyms: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-D-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH trifluoroacetate salt. Molecular formula: C172H265N43O51.C2HF3O2. Mole weight: 3865.21. | |
| Defensin HNP-1 (human) trifluoroacetate salt | Defensin HNP-1 is a peptide secreted by polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It completely inhibits secretion of the exotoxin superantigen TSS toxin-1 (TSST-1) from S. aureus when used at a concentration of 50 ng/ml and inhibits anthrax lethal toxin. Synonyms: DEFA1 Protein; α-Defensin 1; Human Neutrophil Peptide 1; Neutrophil Defensin 1. Grades: ≥95%. Molecular formula: C150H222N44O38S6·xCF3COOH. Mole weight: 3442.04. | |
| Defensin HNP-2 (human) trifluoroacetate salt | Defensin HNP-2 is a peptide with antimicrobial properties that is secreted by human polymorphonuclear leukocytes (PMNs). Defensin HNP-2 binds to recombinant HIV-1 envelope glycoprotein gp120 and human CD4. Synonyms: DEFA2 Protein; α-Defensin 2; Human Neutrophil Peptide 2; Neutrophil Defensin 2. Grades: ≥95%. Molecular formula: C147H217N43O37S6·xCF3COOH. Mole weight: 3370.96. | |
| Defensin HNP-3 (human) trifluoroacetate salt | Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It binds to recombinant, immobilized human surfactant protein D (SP-D; Kd = 55.7 nM) and inhibits focus formation in Madin-Darby canine kidney (MDCK) cells infected with influenza A virus (IAV). Synonyms: DEFA3 Protein; α-Defensin 3; Human Neutrophil Peptide 3; Neutrophil Defensin. Grades: ≥95%. Molecular formula: C151H222N44O40S6·xCF3COOH. Mole weight: 3486.05. | |
| (Des-Gly29)-Liraglutide trifluoroacetate salt | (Des-Gly29)-Liraglutide trifluoroacetate salt is an impurity of Liraglutide. Synonyms: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Arg-Gly-OH trifluoroacetate salt. Molecular formula: C170H262N42O50.C2HF3O2. Mole weight: 3808.16. | |
| (Des-Gly31)-Liraglutide trifluoroacetate salt | (Des-Gly31)-Liraglutide trifluoroacetate salt is an impurity of Liraglutide. Synonyms: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-OH trifluoroacetate salt. Molecular formula: C170H262N42O50.C2HF3O2. Mole weight: 3808.16. | |
| [Des-His1,Glu9]-Glucagon (1-29) amide trifluoroacetate salt | [Des-His1,Glu9]-Glucagon (1-29) amide is a peptide glucagon receptor antagonist (pA2 = 7.25 for glucagon binding to isolated rat liver membranes). It binds to glucagon receptors in a magnesium- and GTP-independent manner to stimulate breakdown of inositol phospholipids by phospholipase C, but has no effect on adenylate cyclase activity, in hepatocytes. In vivo, [Des-His1,Glu9]-glucagon (1-29) amide prevents glucagon-induced hyperglycemia in rabbits and decreases blood glucose in rats with diabetes induced by streptozotocin. Grades: ≥95%. Molecular formula: C148H221N41O47S·xCF3COOH. Mole weight: 3358.65. | |
| (Des-His1)-Glucagon trifluoroacetate salt | (Des-His1)-Glucagon trifluoroacetate salt is an impurity of glucagon. Synonyms: Glucagon (2-29) TFA; H-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH TFA; L-seryl-L-glutaminyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparagyl-L-threonine trifluoroacetate salt. Grades: ≥95%. Molecular formula: C147H218N40O48S.C2HF3O2. Mole weight: 3459.62. | |
| Deshydroxymethyl Losartan Trifluoroacetate Salt | Losartan Impurity C. Group: Biochemicals. Alternative Names: Dehydroxymethyl Losartan Trifluoroacetate Salt; Losartan Impurity C. Grades: Highly Purified. CAS No. 1215727-33-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| (Des-octanoyl)-Ghrelin (human) trifluoroacetate salt | Ghrelin is an endogenous gastrointestinal hormone and neuropeptide that binds to the growth hormone (GH) secretagogue receptor (GHS-R). Synonyms: glycyl-L-seryl-L-seryl-L-phenylalanyl-L-leucyl-L-seryl-L-prolyl-L-α-glutamyl-L-histidyl-L-glutaminyl-L-arginyl-L-valyl-L-glutaminyl-L-glutaminyl-L-arginyl-L-lysyl-L-α-glutamyl-L-seryl-L-lysyl-L-lysyl-L-prolyl-L-prolyl-L-alanyl-L-lysyl-L-leucyl-L-glutaminyl-L-prolyl-L-arginine trifluoroacetate salt. Grades: ≥95%. Molecular formula: C141H235N47O41·xCF3COOH. Mole weight: 3244.67. | |
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