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| Product | Description | |
|---|---|---|
| Trifluridine | 5-Trifluoromethyl-2-deoxyuridine. Grades: USP. CAS No. 70-00-8. Product ID: 3-02759. Molecular formula: C10H11F3N2O5. Mole weight: 296.2. Purity: 0.98. |  |
| Trifluridine | Trifluorothymidine (TFT) and is an inhibitor of thymidine phosphorylase. TFT also inhibits thymidylate synthase (TS), a rate-limiting enzyme of DNA biosynthesis, and is incorporated into DNA. Synonyms: 5-Trifluoromethyl-2'-deoxyuridine; Trifluorothymidine; FTD; 5-Trifluorothymidine; NSC 529182; NSC 75520; Viroptic; α,α,α-Trifluorothymidine; 2'-Deoxy-5-(trifluoromethyl)uridine; Trifluoromethyldeoxyuridine; Trifluridina; Virophta; TFDU. Grades: ≥95%. CAS No. 70-00-8. Molecular formula: C10H11F3N2O5. Mole weight: 296.20. |  |
| Trifluridine | Trifluridine (Trifluorothymidine) is an irreversible and orally active thymidylate synthase inhibitor, and thereby suppressing DNA synthesis. Trifluridine is an antiviral molecule used for research of HSV , rhabdovirus and orthopoxvirus infection. Trifluridine induces cell apoptosis and autophagy. Trifluridine is also an anticancer agent used in studies of metastatic colorectal cancer, gastrointestinal tumors [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Trifluorothymidine; 5-Trifluorothymidine; TFT. CAS No. 70-00-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-A0061. |  |
| Trifluridine Impurity 1 | An impurity of Trifluridine. Trifluridine is a nucleoside analogue antiviral and nucleoside metabolic inhibitor used for the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HERPES SIMPLEX virus. Molecular formula: C17H14ClF3N2O6. Mole weight: 434.76. | |
| Trifluridine Impurity 2 | An impurity of Trifluridine. Trifluridine is a nucleoside analogue antiviral and nucleoside metabolic inhibitor used for the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HERPES SIMPLEX virus. Molecular formula: C17H14ClF3N2O6. Mole weight: 434.76. | |
| Trifluridine Impurity 3 | An impurity of Trifluridine. Trifluridine is a nucleoside analogue antiviral and nucleoside metabolic inhibitor used for the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HERPES SIMPLEX virus. Molecular formula: C6H7ClN2O3. Mole weight: 190.59. | |
| Trifluridine Impurity 4 | An impurity of Trifluridine. Trifluridine is a nucleoside analogue antiviral and nucleoside metabolic inhibitor used for the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HERPES SIMPLEX virus. Molecular formula: C9H10ClN3O3. Mole weight: 243.65. | |
| 2'-Deoxy-5-trifluoromethyluridine-5'-monophosphate | 2'-Deoxy-5-trifluoromethyluridine-5'-monophosphate is a vital compound in the biomedical industry. It is used in the development of antiviral drugs, particularly those aimed at treating RNA-based viruses such as HIV and hepatitis C. Synonyms: α,?α,?α-Trifluoro-5'-thymidylic acid; Trifluridine-5-phosphate; 5-Trifluoromethyl-2'-deoxyuridylic acid. CAS No. 345-02-8. Molecular formula: C10H12F3N2O8P. Mole weight: 376.18. | |
| 5-Carboxy-2-deoxyuridine | 5-Carboxy-2-deoxyuridine is a metabolite of Trifluridine [1]. 5-Carboxy-2-deoxyuridine is a methyl oxidation product of Thymidine that can be formed by menadione-mediated photosensitization of Thymidine [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 14599-46-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W424779. | |
| 5-Carboxy-2'-deoxyuridine | 5-Carboxy-2'-deoxyuridine, is a derivative of Trifluridine, an anti-herpesvirus antiviral drug, used primarily on the eye. Synonyms: 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic Acid; USP Trifluridine Related Compound A. Grades: 98%. CAS No. 14599-46-3. Molecular formula: C10H12N2O7. Mole weight: 272.21. | |
| 5-Trifluorothymidine | Trifluorothymidine is an inhibitor of TS (thymidylate synthase). It is also a substrate used to study the specificity and kinetics of thymidine kinases. Acts as an anti-herpesvirus drug by blocking viral DNA replication. Decreases CRISPR-mediated HDR (homology-directed repair) efficiency. Group: Biochemicals. Alternative Names: Trifluridine; Trifluorothymine Deoxyriboside; α, α, α-Trifluorothymidine; 2-Deoxy-5- (trifluoromethyl) uridine; 5-(Trifluoromethyl)-2-deoxyuridine; Viroptic. Grades: Highly Purified. CAS No. 70-00-8. Pack Sizes: 100mg, 250mg, 1g. Molecular Formula: C??H??F?N?O?, Molecular Weight: 296.2. US Biological Life Sciences. |  Worldwide |
| TAS-102 | TAS-102 is a combination drug composed of the cytotoxic pyrimidine analog Trifluridine (5-trifluoro-2'-deoxythymidine or TFT) and a thymidine phosphorylase inhibitor (TPI) tipiracil hydrochloride, in a molar ratio of 1.0:0.5 (TFT:TPI). TAS-102 is used as a third- or fourth-line treatment of metastatic colorectal cancer. Synonyms: Tipiracil / Trifluridine; Viroptic mixture with 5-CIMU; TAS 102; EX-A1755; Tipiracil hydrochloride / Trifluridine. CAS No. 733030-01-8. Molecular formula: C9H11ClN4O2·HCl·C10H11F3N2O5. Mole weight: 575.328. | |
| Tipiracil HCl | Tipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical trials. TAS-102 consists of the cytotoxin Trifluridine and the thymidine phosphorylase inhibitor (TPI) tipiracil. Trifluridine is incorporated into DNA during DNA synthesis and inhibits tumor cell growth. Tipiracil protects trifluridine from being broken down when taken orally. Synonyms: Tipiracil, TPI. Grades: 0.99. CAS No. 183204-72-0. Molecular formula: C9H12Cl2N4O2. Mole weight: 279.121. | |
| Tipiracil Impurity 3 | An impurity of Trifluridine. Trifluridine is a nucleoside analogue antiviral and nucleoside metabolic inhibitor used for the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HERPES SIMPLEX virus. Synonyms: Trifluridine Impurity 5; Methyl 5-chloro-2,6-dihydroxy-4-pyrimidinecarboxylate; Methyl 5-chloro-2,6-dihydroxypyrimidine-4-carboxylate; CD-0006; AK162189. CAS No. 91447-90-4. Molecular formula: C6H5ClN2O4. Mole weight: 204.57. | |
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