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Trimethoxyphenylsilane can be used as raw materials to prepare macromolecule organosilicon compounds. It can be also used as cross-linking agent of silicon resins, as well as the raw materials of phenyl silicone oil and silicone rubber. Group: Biochemicals. Alternative Names: Trimethoxysilyl) benzene; Phenyltrimethoxysilane . Grades: Highly Purified. CAS No. 2996-92-1. Pack Sizes: 100ml, 250ml, 1L, 4L. Molecular Formula: C9H14O3Si, Molecular Weight: 198.29. US Biological Life Sciences.
1-(2-Amino-3,4,5-trimethoxyphenyl)-ethanone is used to prepare substituted 4-alkyl-2(1H)-quinazolinones with cardiotonic activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 42465-69-0. Pack Sizes: 500mg, 5g. Molecular Formula: C11H15NO4, Molecular Weight: 225.24. US Biological Life Sciences.
1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one is a chalcone compound used as a selective inhibitor of breast cancer resistance protein. Group: Biochemicals. Grades: Highly Purified. CAS No. 53350-27-9. Pack Sizes: 25mg, 50mg. Molecular Formula: C20H22O7. US Biological Life Sciences.
Heterocyclic Organic Compound. Alternative Names: 1-(4-METHOXYPHENYL)-3-(3,4,5-TRIMETHOXYPHENYL)PROP-2-EN-1-ONE. CAS No. 105686-91-7. Molecular formula: C19H20O5. Mole weight: 328.36. Catalog: ACM105686917.
2- (2, 3, 4-Trimethoxyphenyl) pyridine
2- (2, 3, 4-Trimethoxyphenyl) pyridine is a heteroaryl compound which has been shown to inhibit EGF and PDGFreceptor tyrosine kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1243853-02-2. Pack Sizes: 500mg, 5g. Molecular Formula: C14H15NO3, Molecular Weight: 245.27. US Biological Life Sciences.
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2- (2, 3, 4-Trimethoxyphenyl) pyridine-d4
Isotope labelled 2- (2, 3, 4-Trimethoxyphenyl) pyridine is a heteroaryl compound which has been shown to inhibit EGF and PDGFreceptor tyrosine kinase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C14H11D4NO3, Molecular Weight: 249.3. US Biological Life Sciences.
(2, 3, 4-Trimethoxyphenyl) boronic Acid is a reagent used in the synthesis of heteroaryl, mono and bicyclic compounds which may be used as inhibitors for EGF and PDGF receptor tyrosine kinases. Also used in the synthesis of non-steroidal CYP 17 inhibitors in the treatment of prostate cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 118062-05-8. Pack Sizes: 1g, 5g. Molecular Formula: C9H13BO5. US Biological Life Sciences.
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2,3,4-Trimethoxyphenyl Iodide
2,3,4-Trimethoxyphenyl Iodide has been used in the preparation of 1-(2-bromophenyl)-2-phenylethanones. Group: Biochemicals. Grades: Highly Purified. CAS No. 25245-37-8. Pack Sizes: 1g, 10g. Molecular Formula: C9H11IO3, Molecular Weight: 294.089999999999. US Biological Life Sciences.
3-(3,4,5-Trimethoxyphenyl)propanoic acid is found in herbs and spices. 3-(3,4,5-Trimethoxyphenyl)propanoic acid is a constituent of Piper longum (long pepper) and Piper retrofractum (Javanese long pepper). Uses: Scientific research. Group: Natural products. CAS No. 25173-72-2. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-W022390.
3,4,5-Trimethoxyphenylacetic acid
3,4,5-Trimethoxyphenylacetic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 951-82-6. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C11H14O5. US Biological Life Sciences.
Combretastatin is a small organic molecule found in the bark of the African bush willow tree Combretum caffrum. Combretastatin-A4 Prodrug Inducer. Group: Biochemicals. Alternative Names: (Z) -2-Methoxy-5-[2- (3, 4, 5-trimethoxyphenyl) ethenyl]phenol, 3,4,5-Trimethoxy-3-hydroxy-4-methoxy-(Z)-stilbene, CS-A4. Grades: Highly Purified. CAS No. 117048-59-6. Pack Sizes: 10mg. US Biological Life Sciences.
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(E)-4-[2-(3,4,5-Trimethoxyphenyl)ethenyl]-phenol
Heterocyclic Organic Compound. Alternative Names: (E)-4'-Hydroxy-3,4,5-trimethoxystilbene;(E)-4-[2-(3,4,5-Trimethoxyphenyl)ethenyl]-phenol. CAS No. 116519-00-7. Molecular formula: C17H18O4. Mole weight: 286.325. Catalog: ACM116519007.
A cell-permeable, orally bioavailable natural product isolated from the plant species, Piper longum L, which selectively induces cell death in cancer cells that express both wild-type and mutant p53, dose-dependently from 1-15uM, but not in primary normal cells and non-transformed immortalized cells. It significantly enhances wild-type p53 and PUMA expression, and inhibits the expression of several pro-survival proteins, including BCL2, surviving, and XIAP, in various types of cancer cells, but not in normal cells. It elicits ROS and apoptosis in several human cancer cells (EJ, MDA-MB-231, U2OS and MDA-MB-435), possibly through interaction with oxidative stress responders such as GSTP1 and CBR1, and can be reversed by NAC (3mM) in EJ cells. Additionally, it exhibits anti-tumor effects and inhibits the formation of blood vessels in xenograft-tumor mice without obvious toxicity, and inhibits tumor growth and their associated metastases in a MMTV-PyVT breast cancer transgenic mouse model Group: Biochemicals. Grades: Highly Purified. CAS No. 20069-09-4. Pack Sizes: 25mg. US Biological Life Sciences.
A cell-permeable, 3-acryl-acrylamide derivative that acts as a highly potent, selective, and competitive antagonist of prostaglandin E2 receptor (EP2, Kb = 17.8nM). Exhibits about 300-fold selectivity for the EP2 receptor over human EP3, EP4, and IP receptors, about 100- fold selectivity over human EP1, 25-fold selectivity against human FP and TP, and 10-fold selectivity against human DP1 receptors. Does not affect the activity of about 40 enzymes, ion channels, receptors, and neurotransmitters even at higher concentrations (10uM). Shown to significantly reduce the induction of several inflammatory cytokines and chemokines and reduces the opening of blood-brain barrier during neuronal inflammation. Displays good pharmacokinetic properties with a half-life of 1.6 h and brain to plasma ratio of 1.6 in a murine model (5mg/kg i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O?. US Biological Life Sciences.
A cell-permeable cyanoacrylamide compound that acts as a potent, reversible, and selective inhibitor of ribosomal S6 kinase 2 (RSK2; IC50 = 12 and 2.5nM for wild-type and T493M RSK2, respectively). Shown to act by covalently modifying Cys436 at the ATP-binding site. Exhibits good selectivity over NEK2 and PLK1 (IC50 = 530nM and 2.2uM) and does not affect the activity of a panel of 26 other protein kinases. Also shown to block phosphorylation of mitogen and stress activated kinases (MSK) 1, 2, and 3 in PMA-stimulated COS7 cells (IC50 ~100nM) and CREB phosphorylation in PMA- or UV-stimulated HeLa cells (IC50 ~300nM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences.
A cell-permeable, orally bioavailable pyrimidinediamino compound with anti-inflammatory and anti-tumor properties. Acts as a potent, reversible and ATP-competitive inhibitor of Syk kinase (IC50 = 41nM; Ki = 30nM). Exhibits high selectivity over a broad panel of other protein kinases (300nM), ion channels, and enzymes. Blocks Syk-dependent FcR-mediated activation of monocytes/macrophages, and neutrophils and inhibits Anti-IgE-mediated degranulation in cultured human mast cells (EC50 = 56nM as measured by tryptase release). At higher concentrations, it is shown to block adenosine A3 receptors, adenosine transporter, and monoamine transporter (IC50 = 81nM, 1.84uM, and 2.74uM, respectively), and Flt3 autophosphorylation. Shown to reduce immune complex-mediated inflammation in murine models (10mg/kg) and diminish airway hyper-responsiveness in asthma models. Group: Biochemicals. Grades: Highly Purified. CAS No. 841290-80-0. Pack Sizes: 5mg. US Biological Life Sciences.
An intermediate for the synthesis of mivacurium. Group: Biochemicals. Alternative Names: trans-6, 7-Dimethoxy-2- (3-hydroxypropyl) -2- (methyl-13C) -1-[ (3, 4, 5-trimethoxyphenyl) methyl]-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Trans-BTP Dioxolane is a PAF receptor antagonist. This compound demonstrates competitive antagonism of PAF in a rabbit washed platelet assay (Ki = 0.3 μM). Synonyms: trans-BTP Dioxolane; trans-(±)-2,4-bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane; (2R,4R)-2,4-bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane. Grades: ≥98%. CAS No. 116673-45-1. Molecular formula: C21H26O8. Mole weight: 406.4.
2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxin-5-amine can be used to synthesize derivatives of 2- (3, 4, 5-trimethoxyphenylamino) -6- (3-acetamidophenyl) pyrazine as B-RAF inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 119895-70-4. Pack Sizes: 5mg, 50mg. Molecular Formula: C8H5F4NO2, Molecular Weight: 223.12. US Biological Life Sciences.
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2,3,4-Trimethoxybenzyl alcohol
An impurity of Trimetazidine. Trimetazidine is a drug for angina pectoris. Synonyms: (2,3,4-trimethoxyphenyl)methanol. CAS No. 71989-96-3. Molecular formula: C10H14O4. Mole weight: 198.22.
2-Bromo-4-hydroxymethylpyridine
2-Bromo-4-hydroxymethylpyridine is used to synthesize aza- and diazabiphenyl analogs of the antitubercular drug (6S) -2-nitro-6-{[4- (trifluoromethoxy) benzyl]oxy}-6, 7-dihydro-5H-imidazo[2, 1-b][1, 3]oxazine (PA-824). It is also used to N3/8-disubstituted 3, 8-diazabicyclo[3. 2. 1]octane analogues of 3, 8-bis[2- (3, 4, 5-trimethoxyphenyl) pyridin-4-yl]methyl-piperazine with antiproliferative properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 118289-16-0. Pack Sizes: 500mg, 1g. Molecular Formula: C6H6BrNO, Molecular Weight: 188.02. US Biological Life Sciences.