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Troglitazone. Group: Biochemicals. Grades: Purified. CAS No. 97322-87-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Troglitazone
Troglitazone is an orally active PPARγ agonist, with EC 50 s of 550 nM and 780 nM for human and murine?PPARγ receptor, respectively. Troglitazone has anticancer activity, prevents and inhibits the development of type 2 diabetes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CS-045. CAS No. 97322-87-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50935.
An oral hypoglycemic agent which improves insulin sensitivity and decreases hepatic glucose production. Group: Biochemicals. Alternative Names: 5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]-phenyl]methyl]-2,4-thiazolidinedione, Romglizone, CS-045, CI-991,Noscal. Grades: Highly Purified. CAS No. 97322-87-7. Pack Sizes: 10mg. US Biological Life Sciences.
An antidiabetic thiazolidinedione (TDZ) drug with anti-inflammatory and anti-tumor activities. A potent and selective PPARγ agonist. The EC50 values for transactivation of human and murine PPARγ in a cell-based assay are 0.55 and 0.78uM, respectively. Group: Biochemicals. Alternative Names: (±)-5-[4-[(6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy]benzyl]-2,4-thiazolidinedione. Grades: Highly Purified. CAS No. 97322-87-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Troglitazone (5-phenyl]methyl]-2,4-thiazolidinedione, Romglizone, BRN 4338399, CS-045, CI-991, GR 92132X)
Potent and selective PPARgamma agonist with no activation of PPARalpha and PPARdelta. Anti-diabetic agent with potent glucose-lowering effects and decreasing insulin resistance in adipose tissues. Stimulates adipogenesis. Apoptosis and cell cycle arrest inducer in several cancer cell lines. Anti-inflammatory. Inhibits vascular smooth muscle cell (VSMC) migration. Group: Biochemicals. Alternative Names: 5-phenyl]methyl]-2,4-thiazolidinedione, Romglizone, BRN 4338399, CS-045, CI-991, GR 92132X. Grades: Highly Purified. CAS No. 97322-87-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Troglitazone-[d4]
One of the isotopic labelled form of Troglitazone, which could be used for the treatment of diabetes and inflammation. Synonyms: 5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione-d4. Molecular formula: C24H23NO5SD4. Mole weight: 445.57.
GW1929
Potent and subtype-selective (>1000-fold) PPARgamma agonist. Angiogenesis and apoptosis inhibitor. Anti-inflammatory. Anti-hyperglycemic and anti-hyperlipidemic agent. GW1929 is an antidiabetic; the glucose-lowering effect in rats is 100-fold more potent than that of troglitazone. Group: Biochemicals. Alternative Names: N-(2-Benzoylphenyl)-L-tyrosine PPARγ Agonist; (2S) - ( (2-Benzoylphenyl) amino-3- [4- [2- (methylpyridin-2-ylamino) ethoxy] phenyl] propionic acid. Grades: Highly Purified. CAS No. 196808-24-9. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C30H29N3O4. US Biological Life Sciences.
Worldwide
Rosiglitazone maleate
Rosiglitazone exhibits insulin-sensitising activity 60- to 200-fold higher than that of troglitazone, englitazone, or piogliazone in rodent models of insulin ressitance. Uses: Hypoglycemic agents. Synonyms: Rosiglitazone Maleate; Avandia; Avandaryl; BRL-49653C; BRL49653C; BRL 49653C; BRL-49653-C. Grade: >98%. CAS No. 155141-29-0. Molecular formula: C18H19N3O3S.C4H4O4. Mole weight: 473.5.
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