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Tropisetron (SDZ-ICS-930 free base) is an orally active anti-inflammatory and antiemetic agent. Tropisetron is 5-HT 3 R antagonists with a K i of 5.3 nM. Tropisetron is also a partial agonist of α7 nicotinic receptor ( α7 nAChR ) with an EC 50 of 1.3 μM. In addition, Tropisetron has antitumor and neuroprotective effects [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SDZ-ICS-930 free base. CAS No. 89565-68-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0072.
Tropisetron Citrate
Tropisetron Citrate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1251773-00-8. Molecular formula: C23H28N2O9. Mole weight: 476.48. Catalog: APB1251773008.
Tropisetron-d4
Tropisetron-d4. Group: Biochemicals. Alternative Names: 1H-Indole-3-carboxylic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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Tropisetron hydrochloride
Tropisetron is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor. It is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy. Synonyms: ICS 205-930. Grade: >98%. CAS No. 105826-92-4. Molecular formula: C17H20N2O2.HCl. Mole weight: 320.81.
Tropisetron Hydrochloride
Specific serotonin (5-HT3) receptor antagonist. Antiemetic. Group: Biochemicals. Alternative Names: 1H-Indole-3-carboxylic Acid. Grades: Highly Purified. CAS No. 105826-92-4. Pack Sizes: 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences.
Worldwide
Tropisetron Hydrochloride
Tropisetron Hydrochloride (SDZ-ICS-930) is an effective neuroprotective agent that acts as a 5-HT3 receptor antagonist, a calmodulin inhibitor, and an α7-nAChR receptor agonist, with an IC 50 of 70.1 nM for the 5-HT3 receptor. Tropisetron Hydrochloride has anti-inflammatory properties and immune-regulating functions, effectively alleviating symptoms associated with chemotherapy and post-surgery. Tropisetron Hydrochloride reduces Ab (HY-P4867)-induced hippocampal neuroinflammation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SDZ-ICS-930. CAS No. 105826-92-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0020.
Tropisetron Hydrochloride
Tropisetron Hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrochloride. Product Category: Indoles. CAS No. 105826-92-4. Molecular formula: C17H20N2O2·HCl. Mole weight: 320.8. Purity: 98%+. Product ID: ACM105826924-1. Alfa Chemistry ISO 9001:2015 Certified.
Tropisetron Hydrochloride
Tropisetron is an indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy-and radiotherapy-induced nausea and vomiting. Alternative Names: Tropisetronum. Novaban. [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 1H-indole-3-carboxylate. CAS No. 89565-68-4. Product ID: API89565684. Molecular formula: C17H20N2O2. Mole weight: 284.35. SMILES: CN1C2CCC1CC(C2)OC(=O)C3=CNC4=CC=CC=C43. Category: Antiemetic APIs.
Tropisetron, also known as ICS-205930, is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic to treat nausea and vomiting following chemotherapy, although it has been used experimentally as an analgesic in cases of fibromyalgia. Uses: Antiemetics. Synonyms: Navoban. ICS 205-930. (1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1methyl-indole-3-carboxylate. Grade: >98%. CAS No. 89565-68-4. Molecular formula: C17H20N2O2. Mole weight: 284.35.
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