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| Product | Description | |
|---|---|---|
| TRPC6 inhibitor | TRPC6 inhibitor. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1333207-63-8. Molecular formula: C21H24Cl3N3O. Mole weight: 440.79. Catalog: APB1333207638. |  |
| 9-Phenanthrol | 9-Phenanthrol (9-Hydroxyphenanthrene) is a selective TRPM4 inhibitor with an IC 50 of 17 μM. 9-Phenanthrol has no inhibitory activity on TRPM5, TRPC6, and CFTR. 9-Phenanthrol can be used for the research of ischemia-reperfusion injury [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 9-Hydroxyphenanthrene; NSC 50554. CAS No. 484-17-3. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg. Product ID: HY-108457. |  |
| Hyperforin DCHA | Key constituent of St. John's wort. Shows properties of potential pharmacological interest, including anti-bacterial, anti-malarial, anti-inflammatory, anti-cancer and anti-angiogenic effects. Anti-depressant and anxiolytic compound. Specific activator of TRPC6 channels. Inhibits the re-uptake of neurotransmitters in synapses (serotonin, norepinephrine, dopamine, GABA, glutamate). Activator of the pregnane X receptor (PXR). Regulates expression of the cytochrome P450 CYP3A4 and CYP2C9 and hepatic drugs metabolism. Potential anti-Alzheimer compound. Potent SIRT1 (sirtuin 1) and SIRT2 (sirtuin 2) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 238074-03-8. Pack Sizes: 500ug, 1mg. Molecular Formula: C35H51O4 C12H24N. US Biological Life Sciences. |  Worldwide |
| Larixyl acetate | Larixyl acetate is a potent and selective TRPC6 inhibitor with IC 50 values of 0.58 μM and 6.83 μM against hTRPC6-YFP and hTRPC3-YFP , respectively. Larixyl acetate prevents HPV and is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 4608-49-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101795. | |
| Larixyl Acetate | Larixyl acetate is a potent and selective TRPC6 inhibitor with IC50 values of 0.58 μM and 6.83 μM against hTRPC6-YFP and hTRPC3-YFP, respectively. Larixyl acetate prevents HPV and is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (Αs,1S,4S,4As,8Ar)-4-(Acetyloxy)-Α-Ethenyldecahydro-Α,5,5,8A-Tetramethyl-2-Methylene-1-Naphthalenepropanol. Product Category: Inhibitors. CAS No. 4608-49-5. Molecular formula: C22H36O3. Mole weight: 348.52. Purity: 0.9621. Canonical SMILES: CC(=O)OC1CC(=C)C([C@]2(C1C(CCC2)(C)C)C)CCC(C)(C=C)OC(=O)C. Product ID: ACM4608495. Alfa Chemistry ISO 9001:2015 Certified. |  |
| ML204 | ML204 is a novel and potential TRPC4 Channel inhibitor. ML204 inhibited TRPC4β-mediated intracellular Ca(2+) rise with an IC(50) value of 0.96 μm and exhibited 19-fold selectivity against muscarinic receptor-coupled TRPC6 channel activation. Synonyms: 4-Methyl-2-piperidin-1-ylquinoline; ML204; ML 204; ML-204. Grades: > 98%. CAS No. 5465-86-1. Molecular formula: C15H18N2. Mole weight: 226.323. |  |
| ML204 | ML204 is a potent, selective TRPC4/TRPC5 channel inhibitor, with at least 19-fold selectivity against TRPC6 and no appreciable effect on all other TRP channels, nor on voltage-gated sodium, potassium, or Ca 2+ channels [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5465-86-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12949. | |
| ML204 hydrochloride | ML204 hydrochloride is a novel, potent, selective TRPC4/TRPC5 channel inhibitor, with at least 19-fold selectivity against TRPC6 and no appreciable effect on all other TRP channels, nor on voltage-gated sodium, potassium, or Ca 2+ channels [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2070015-10-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12949A. | |
| SAR7334 | SAR7334, a TRPC6 inhibitor, could be valuable in studying sorts of diseases related to TRPC. Uses: Sar7334 is a trpc6 inhibitor that could be valuable in studying sorts of diseases related to trpc. Synonyms: SAR7334; CPA1588; SAR 7334; CPA 1588; SAR-7334; CPA-1588; 4-(((1R,2R)-2-((R)-3-aminopiperidin-1-yl)-2,3-dihydro-1H-inden-1-yl)oxy)-3-chlorobenzonitrile; 1333207-63-8; 1333210-07-3; C21H22ClN3O. Grades: 98%. CAS No. 1333210-07-3. Molecular formula: C21H22ClN3O. Mole weight: 367.87. | |
| SAR7334 | SAR7334 is a potent and specific TRPC6 inhibitor, inhibiting TRPC6 currents with IC50 of 7.9 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1333210-07-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15699. | |
| SAR7334 hydrochloride | The hydrochloride salt form of SAR7334, a TRPC6 inhibitor, could be valuable in studying sorts of diseases related to TRPC. Uses: The hydrochloride salt form of sar7334 is a trpc6 inhibitor that could be valuable in studying sorts of diseases related to trpc. Synonyms: SAR7334 hydrochloride; CPA1588 hydrochloride; SAR 7334 hydrochloride; CPA 1588 hydrochloride; SAR-7334 hydrochloride; CPA-1588 hydrochloride; 4-(((1R,2R)-2-((R)-3-aminopiperidin-1-yl)-2,3-dihydro-1H-inden-1-yl)oxy)-3-chlorobenzonitrile; 1333207-63-8; 1333210-07-3; C21H22ClN3O. Grades: 97%. CAS No. 1333207-63-8. Molecular formula: C21H24Cl3N3O. Mole weight: 440.79. | |
| TRPC6-IN-3 | TRPC6-IN-3 (compound 17) is a potent, orally active transient receptor potential C6 ion channel (TRPC6) inhibitor. TRPC6-IN-3 modulates not only intracellular calcium concentration, but also membrane potential by modulating the flux of cations including calcium and sodium ions. TRPC6-IN-3 can be used in research of respiratory system [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2311863-36-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148129. | |
| Zerencotrep | Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (-)-englerin A-activated TRPC4/TRPC5 channels, with IC50s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pico145; HC-608. CAS No. 1628287-16-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101507. | |
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