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| Product | Description | |
|---|---|---|
| Tucidinostat | Tucidinostat (Chidamide) is a potent and orally bioavailable HDAC enzymes class I ( HDAC1/2/3 ) and class IIb ( HDAC10 ) inhibitor, with IC 50 s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 ( IC 50 s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Chidamide; HBI-8000; CS 055. CAS No. 1616493-44-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109015. |  |
| Tucidinostat | Tucidinostat Inhibitor. Uses: Scientific use. Product Category: T4481. CAS No. 1616493-44-7. |  |
| Tucidinostat-[d4] | Tucidinostat-[d4] is an isotope labelled compound of Tucidinostat. Chidamide is a newly designed histone deacetylase inhibitor that induces an antitumor effect in various cancer by increasing the acetylation levels of histone H3 and decreasing histone deacetylase (HDAC) activity, inducing apoptosis. It is a potential utility of Chidamide for the treatment of Myelodysplastic syndromes. Synonyms: N-(2-Amino-4-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propenyl]amino]methyl]-benzamide-d4; Chidamide-d4; HBI-800 D4. Grade: 98% by CP. Molecular formula: C22H15D4FN4O2. Mole weight: 394.43. |  |
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