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Tylosin is a 16-member-ring macrolide produced through the fermentation of Streptomyces fradiae, a species of actinobacteria found in soil. It is effective against gram-positive bacteria, Mycoplasma species and certain gram-negative bacteria. With other macrolides, tylosin inhibits protein synthesis by binding to the 50S subunit of the bacterial ribosome and disrupting aminoacyl-and peptidyl-tRNA transcription. This is believed to ultimately prevent the bacteria from reproducing. Synonyms: Tylosine; Tylocine; Tylosinum; Fradizine; NSC758961; (10E,12E)-(3R,4S,5S,6R,8R,14S,15R)-14-((6-deoxy-2,3-di-O-methyl-beta-D-allopyranosyl)oxymethyl)-5-((3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-3-dimethylamino-beta-D-glucopyranosyl)oxy)-6-formylmethyl-3-hydroxy-4,8,12-trimethyl-9-oxoheptadeca-10,12-dien-15-olide. Grades: >98%. CAS No. 1401-69-0. Molecular formula: C46H77NO17. Mole weight: 916.10.
Tylosin
Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 1401-69-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0519A.
Tylosin, 3-?acetate
Tylosin, 3-acetate is an impurity of Tylosin, which is a macrolide antibiotic and bacteriostatic feed additive used in veterinary medicine with broad-spectrum activity against gram-positive bacteria and limited activity against gram-negative bacteria. Synonyms: 3-O-Acetyltylosin; (4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-(((2R,3R,4R,5S,6R)-5-(((2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-16-ethyl-15-((((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)-5,9,13-trimethyl-2,10-dioxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-4-yl acetate; Tylosin 3-Acetate. Grades: ≥95%. CAS No. 63409-10-9. Molecular formula: C48H79NO18. Mole weight: 958.14.
Tylosin A
A highly purified form of tylosin A. It is a macrolide antibiotic, which is considered to be the major component of tylosin (comprises approximately 90% of tylosin). However, tylosins B, C and D contribute to the overall potency of tylosin. Synonyms: Tylosin; [4R-(4R*, 5S*, 6S*, 7R*, 9R*, 11E, 13E, 15R*, 16R*)]-15-[[(6-Deoxy-2, 3-di-O-methyl-β-D-allopyranosyl)oxy]methyl]-6-[[3, 6-dideoxy-4-O-(2, 6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3-(dimethylamino)-β-D-glucopyranosyl]oxy]-16-ethyl-4-hydroxy-5, 9, 13-trimethyl-2, 10-dioxooxacyclohexadeca-11, 13-diene-7-acetaldehyde; Fradizine; Tylocine; Tylosine. Grades: ≥99.0% by HPLC. CAS No. 8026-48-0. Molecular formula: C46H77NO17. Mole weight: 916.10.
Tylosin A
Tylosin A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 8026-48-0. Molecular Formula: C46H77NO17. Mole Weight: 916.11. Catalog: APB8026480.
Tylosin B
It is a 16-membered macrolide antibiotic and a metabolite of Tylosin. It is also a precursor of Tilmicosin. Synonyms: Desmycosin; 4A-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)tylosin; Demycarosyltylosin. Grades: ≥95.0% by HPLC. CAS No. 11032-98-7. Molecular formula: C39H65NO14. Mole weight: 771.93.
Tylosin monotartrate
Tylosin tartrate is a macrolide antibiotic produced by Streptomyces. Tylosin tartrate is an antimicrobial for gram-positive bacteria and mycoplasma. It can be used to prevent and treat respiratory diseases such as mycoplasma pneumonia, pleuropneumonia, swine pneumonia, Haemophilus parasuis, streptococcus suis, and other tissue infections. Synonyms: Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (1:1); Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (1:1) (salt); Tylosin, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (salt); Pharmasin; Tylan Injectable; Tylan Soluble; Tylosin tartrate. Grades: >98%. CAS No. 74610-55-2. Molecular formula: C50H83NO23. Mole weight: 1066.19.
Tylosin phosphate
Tylosin phosphate is a broad spectrum antibiotic against Gram-positive organisms and a limited range of Gram-negative organisms. Synonyms: Tylan; Farmazin TB; Pharmasine TB; Tylan 40 premix; Tylan 10 premix. Grades: >98%. CAS No. 1405-53-4. Molecular formula: C46H80NO21P. Mole weight: 1014.1.
Tylosin phosphate
Tylosin phosphate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 1405-53-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0519B.
Tylosin tartrate
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C46H77NO17 ¢C4H4O6. CAS No. 1405-54-5. Prepack ID 90028737-1g. Molecular Weight 1066.19. See USA prepack pricing.
Tylosin tartrate
25g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C49H81NO23. CAS No. 74610-55-2. Prepack ID 12004989-25g. Molecular Weight 1052.16. See USA prepack pricing.
Tylosin tartrate
5g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C49H81NO23. CAS No. 74610-55-2. Prepack ID 12004989-5g. Molecular Weight 1052.16. See USA prepack pricing.
Tylosin tartrate
Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 74610-55-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0519.
Tylosin tartrate
Tylosin tartrate is a macrolide antibiotic produced by Streptomyces. Tylosin tartrate is an antimicrobial for gram-positive bacteria and mycoplasma. Synonyms: Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (salt); Tylosin, [R-(R*,R*)]-2,3-dihydroxybutanedioate (salt). Grades: 95%. CAS No. 1405-54-5. Molecular formula: C44H77NO17.xC4H6O6. Mole weight: 892.08 (free base).
Tylosin Tartrate
Heterocyclic Organic Compound. CAS No. 1045-54-5. Catalog: ACM1045545.
Tylosin Tartrate
Tylosin Tartrate is a macrolide antibiotic isolated from a strain of Streptomycetes fradiae found in soil from Thailand. Antibacterial. Group: Biochemicals. Alternative Names: Tylosin (2R,3R)-2,3-dihydroxybutanedioate (1:1) (Salt; Tylosin, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (Salt); Oxacyclohexadecane Tylosin deriv.; Pharmasin; Tylan Injectable; Tylan Soluble; Tylosin Tartrate. Grades: Highly Purified. CAS No. 74610-55-2. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C??H??NO??, Molecular Weight: 1066.19. US Biological Life Sciences.
Worldwide
20-Deoxo-20-(1-piperidinyl)tylosin
20-Deoxo-20-(1-piperidinyl)tylosin, a formidable antibiotic with exceptional potency, finds its purpose in combating an array of bacterial infections. Its unrivaled capacity to impede bacterial protein synthesis materializes through binding with the 50S ribosomal subunit. Synonyms: Tylosin, 20-deoxo-20-(1-piperidinyl)-; 1003024-00-7; (4R,5S,6S,7R,9R,15R,16S)-6-[(2R,3S,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-[[(2R,3R,4S,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-7-(2-piperidin-1-ylethyl)-1-oxacyclohexadeca-11,13-diene-2,10-dione. CAS No. 1003024-00-7. Molecular formula: C51H88N2O16. Mole weight: 985.25.
20-Deoxo-20-(1-piperidinyl)tylosin
20-Deoxo-20-(1-piperidinyl)tylosin. Group: Biochemicals. Grades: Highly Purified. CAS No. 1003024-00-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
23-De(mycinosyi) tylosin
Cas No. 79592-92-0.
23-De(mycinosyloxy)tylosin
23-De(mycinosyloxy)tylosin is a macrolide antibiotic produced by Streptomyces fradiae GS76 and GS48. It has anti-gram-positive bacteria and weak anti-gram-negative bacteria and mycoplasma activity. Synonyms: YT-3927. CAS No. 79404-97-0. Molecular formula: C38H63NO12. Mole weight: 725.90.
23-O-Desmycinosyl-tylosin
Tylosin EP Impurity A, an impurity of Tylosin, is a macrolide antibiotic produced by Streptomyces fradiae GS76 and GS48. It has anti-gram-positive bacteria and weak anti-gram-negative bacteria and mycoplasma activity. Synonyms: 22-O-Demycinosyltylosin; 23-O-Demycinosyltylosin; Demycinosyltylosin; Tylosin EP Impurity A; 23-De(mycinosyl)tylosin; Antibiotic YO 9010; BRN 4649503; Tylosin, 23-O-de(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)-; 23-O-De(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)tylosin; 23-Demycinosyltylosin. Grades: ≥85.0%. CAS No. 79592-92-0. Molecular formula: C38H63NO13. Mole weight: 741.90.
2',4'''-O-DiTMS Tylosin 3-Methylbytanoate
2',4'''-O-DiTMS Tylosin 3-Methylbytanoate is an intermediate in synthesizing Tylvalosin-d9, a labelled analogue of Tylvalosin, which is an antibacterial agent that is shown through study as a good inhibitor of gram-positive bacteria. Synonyms: (2S,3S,4R,6S)-6-(((2R,3S,4S,5R,6R)-6-(((4R,5S,6S,7R,9R,11E,13E,15R,16R)-15-((((2R,3R,4S,5R,6R)-3,4-Dimethoxy-6-methyl-5-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)methyl)-16-ethyl-4-hydroxy-5,9,13-trimethyl-2,10-dioxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-6-yl)oxy)-4-(dimethylamino)-2-methyl-5-((trimethylsilyl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-4-hydroxy-2,4-dimethyltetrahydro-2H-pyran-3-yl 3-Methylbutanoate. Molecular formula: C57H101NO18Si2. Mole weight: 1144.58.
2',4'''-O-DiTMS Tylosin 3-Methylbytanoate
2',4'''-O-DiTMS Tylosin 3-Methylbytanoate is an intermediate in synthesizing Tylvalosin-d9 (T898212), a labelled analogue of Tylvalosin (T898210), which is an antibacterial agent that is shown through study as a good inhibitor of gram-positive bacteria. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C57H101NO18Si2. US Biological Life Sciences.
Worldwide
4',2''-O-Di(trimethysilyl)tylosin
4',2''-O-Di(trimethysilyl)tylosin is a reactant used in the antibacterial Tylosin derivatives preparation process. Synonyms: 2A,4C-Bis-O-(trimethylsilyl)-tylosin. CAS No. 114442-77-2. Molecular formula: C52H93NO17Si2. Mole weight: 1060.46.
4, 2-O-Di (trimethysilyl)tylosin
4, 2-O-Di (trimethysilyl)tylosin is a reactant used in the preparation of antibacterial Tylosin (T947650) derivatives. Group: Biochemicals. Alternative Names: 2A,4C-Bis-O-(trimethylsilyl)-tylosin. Grades: Highly Purified. CAS No. 114442-77-2. Pack Sizes: 10mg. US Biological Life Sciences.
4-O-Chloroacetyl-4, 2-O-di (trimethysilyl)tylosin is an acyl derivative of Tylosin (T947650). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
4-O-Chloroacetyl-4, 2-O-di (trimethysilyl)tylosin 3,3-Diacetate is an acyl derivative of Tylosin (T947650). Group: Biochemicals. Alternative Names: 3, 3-O-Diacetyl-4-O-chloroacetyltylosin-4, 2-O-di (trimethysilyl) tylosin. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
4"'-O-Chloroacetyl-4',2''-O-di(trimethysilyl)tylosin 3'''-Acetate is an intermediate used in the synthesis of Tylosin 3-Acetate, which is a new acyl derivative of Tylosin produced by microbial transformation. Synonyms: 3'''-O-Acetyl-4'"-O-chloroacetyltylosin-4',2''-O-di(trimethysilyl)tylosin. Molecular formula: C56H96ClNO19Si2. Mole weight: 1178.98.
4'''-O-Chloroacetyl-tylosin
4'''-O-Chloroacetyl-tylosin is an intermediate used in the synthesis of Tylosin 3-Acetate, which is a new acyl derivative of Tylosin produced by microbial transformation. Molecular formula: C48H78ClNO18. Mole weight: 992.58.
4'''-O-Chloroacetyl-tylosin 3-Acetate
4'''-O-Chloroacetyl-tylosin 3-Acetate is an acyl derivative of Tylosin. Synonyms: 3-O-Acetyl-4'"-O-chloroacetyltylosin. Molecular formula: C50H80ClNO19. Mole weight: 1034.62.
4-O-Chloroacetyl-tylosin 3-Acetate
4-O-Chloroacetyl-tylosin 3-Acetate. Group: Biochemicals. Alternative Names: 3-O-Acetyl-4-O-chloroacetyltylosin. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
O-Tri-t-Butyldimethylsilyl Tylosin Acetate
An intermediate used in the synthesis of Tylosin-d3, which is labelled Tylosin. Tylosin is a macrolide antibiotic isolated from a strain of Streptomycetes fradiae found in soil from Thailand. Antibacterial. Molecular formula: C65H119NO18Si3. Mole weight: 1286.89.
t-Butyldimethylsilyl Tylosin
t-Butyldimethylsilyl Tylosin is an intermediate used in the synthesis of Tylosin-d3, which is labelled Tylosin. Tylosin is a macrolide antibiotic isolated from a strain of Streptomycetes fradiae found in soil from Thailand. Antibacterial. Molecular formula: C52H91NO17Si. Mole weight: 1030.36.
t-Butyldimethylsilyl Tylosin Acetate
t-Butyldimethylsilyl Tylosin Acetate is an intermediate used in the synthesis of Tylosin-d3, which is labelled Tylosin. Tylosin is a macrolide antibiotic isolated from a strain of Streptomycetes fradiae found in soil from Thailand. Antibacterial. Molecular formula: C54H93NO18Si. Mole weight: 1072.4.
20-oxo-5-O-mycaminosyltylactone 23-monooxygenase
A cytochrome P-450 heme-thiolate enzyme. Involved in the biosynthetic pathway of the macrolide antibiotic tylosin, which is produced by several species of Streptomyces bacteria. Group: Enzymes. Synonyms: tylH1 (gene name). Enzyme Commission Number: EC 1.14.13.186. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0785; 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase; EC 1.14.13.186; tylH1 (gene name). Cat No: EXWM-0785.
23S rRNA (guanine748-N1)-methyltransferase
The enzyme specifically methylates guanine748 at N1 in 23S rRNA. The methyltransferase RlmAII confers resistance to the macrolide antibiotic tylosin in the drug-producing strain Streptomyces fradiae. Group: Enzymes. Synonyms: Rlma(II); Rlma2; 23S rRNA m1G748 methyltransferase; RlmaII; Rlma II; tylosin-resistance methyltransferase RlmA(II); TlrB; rRNA large subunit methyltransferase II. Enzyme Commission Number: EC 2.1.1.188. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1787; 23S rRNA (guanine748-N1)-methyltransferase; EC 2.1.1.188; Rlma(II); Rlma2; 23S rRNA m1G748 methyltransferase; RlmaII; Rlma II; tylosin-resistance methyltransferase RlmA(II); TlrB; rRNA large subunit methyltransferase II. Cat No: EXWM-1787.
An intermediate in synthesizing Tylosin-d3. It is a labelled Tylosin. Tylosin is a macrolide antibiotic isolated from a strain of Streptomycetes fradiae found in soil from Thailand. Antibacterial. Molecular formula: C66H121NO18Si3. Mole weight: 1300.92.
Antibiotic N-1
Antibiotic N-1 is extracted from Streptomyces thermotolerans. It has the activity against gram-positive bacteria and mycoplasma. Synonyms: Tylosin, 23-O-de(6-deoxy-2,3-di-O-methyl-b-D-allopyranosyl)-, 3-acetate 4B-(3-methylbutanoate) (9CI). CAS No. 74290-44-1. Molecular formula: C45H73NO15. Mole weight: 868.06.
demethyllactenocin mycarosyltransferase
The enzyme participates in the biosynthetic pathway of the macrolide antibiotic tylosin, which is produced by several species of Streptomyces bacteria. Group: Enzymes. Synonyms: tylCV (gene name); tylC5 (gene name). Enzyme Commission Number: EC 2.4.1.318. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2554; demethyllactenocin mycarosyltransferase; EC 2.4.1.318; tylCV (gene name); tylC5 (gene name). Cat No: EXWM-2554.
demethylmacrocin O-methyltransferase
Requires Mg2+. The enzyme, isolated from the bacterium Streptomyces fradiae, is involved in the biosynthesis of the macrolide antibiotic tylosin. The 2-hydroxy group of a 6-deoxy-D-allose moiety in demethylmacrocin acts as the methyl acceptor. Also acts on demethyllactenocin, giving lactenocin. Not identical with EC 2.1.1.101 macrocin O-methyltransferase. Group: Enzymes. Synonyms: demethylmacrocin methyltransferase; DMOMT. Enzyme Commission Number: EC 2.1.1.102. CAS No. 120313-64-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1700; demethylmacrocin O-methyltransferase; EC 2.1.1.102; 120313-64-6; demethylmacrocin methyltransferase; DMOMT. Cat No: EXWM-1700.
The enzyme is involved in the biosynthesis of mycaminose, an essential structural component of the macrolide antibiotic tylosin, which is produced by the bacterium Streptomyces fradiae. Group: Enzymes. Synonyms: TylM1. Enzyme Commission Number: EC 2.1.1.235. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1838; dTDP-3-amino-3,6-dideoxy-α-D-glucopyranose N,N-dimethyltransferase; EC 2.1.1.235; TylM1. Cat No: EXWM-1838.
dTDP-4-dehydro-6-deoxy-α-D-gulose 4-ketoreductase
The enzyme forms an activated deoxy-α-D-allose, which is converted to mycinose after attachment to the aglycones of several macrolide antibiotics, including tylosin, chalcomycin, dihydrochalcomycin, and mycinamicin II. Group: Enzymes. Synonyms: dTDP-4-dehydro-6-deoxygulose reductase; tylD (gene name); gerKI (gene name); chmD (gene name); mydI (gene name). Enzyme Commission Number: EC 1.1.1.364. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0281; dTDP-4-dehydro-6-deoxy-α-D-gulose 4-ketoreductase; EC 1.1.1.364; dTDP-4-dehydro-6-deoxygulose reductase; tylD (gene name); gerKI (gene name); chmD (gene name); mydI (gene name). Cat No: EXWM-0281.
dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase
The enzyme is involved in the biosynthetic pathway of dTDP-6-deoxy-α-D-allose, which is converted to mycinose after attachment to the aglycones of several macrolide antibiotics, including tylosin, chalcomycin, dihydrochalcomycin, and mycinamicin II. Group: Enzymes. Synonyms: dTDP-deoxyglucose 3-epimerase; dTDP-4-keto-6-deoxy-D-glucose 3-epimerase; dTDP-4-keto-6-deoxyglucose 3-epimerase; gerF (gene name); tylJ (gene name); chmJ (gene name); mydH (gene name). Enzyme Commission Number: EC 5.1.3.27. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5413; dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase; EC 5.1.3.27; dTDP-deoxyglucose 3-epimerase; dTDP-4-keto-6-deoxy-D-glucose 3-epimerase; dTDP-4-keto-6-deoxyglucose 3-epimerase; gerF (gene name); tylJ (gene name); chmJ (gene name); mydH (gene name). Cat No: EXWM-5413.
macrocin O-methyltransferase
Requires Mg2+, Mn2+ or Co2+. The 3-hydroxy group of the 2-O-methyl-6-deoxy-D-allose moiety in the macrolide antibiotic macrosin acts as methyl acceptor, generating tylosin, another macrolide antibiotic. Isolated from the bacterium Streptomyces fradiae. Not identical with EC 2.1.1.102, demethylmacrocin O-methyltransferase. Group: Enzymes. Synonyms: macrocin methyltransferase; S-adenosyl-L-methionine-macrocin O-methyltransferase; MOMT (ambiguous); tylF (gene name). Enzyme Commission Number: EC 2.1.1.101. CAS No. 79468-52-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1699; macrocin O-methyltransferase; EC 2.1.1.101; 79468-52-3; macrocin methyltransferase; S-adenosyl-L-methionine-macrocin O-methyltransferase; MOMT (ambiguous); tylF (gene name). Cat No: EXWM-1699.
Macrolide glycosyltransferase from Streptomyces lividans, Recombinant
UDP glycosyltransferases (UGT) are a superfamily of enzymes that catalyzes the addition of the glycosyl group from a UTP-sugar to a small hydrophobic molecule. Group: Enzymes. Synonyms: UDP-glucose: oleandomycin β-glucosyltransferase; UDP-glucose: tylosin β-glucosyltransferase; UDP-glucose: erythromycin β-glucosyltransferase; Macrolide glycosyltransferase; Oleandomycin glycosyltransferase. Enzyme Commission Number: EC 2.4.1.-. Purity: > 95 % as judged by SDS-PAGE. Macrolide glycosyltransferase. Mole weight: 45551.4 Da. Storage: Store at 4°C (shipped at room temperature). Form: Supplied in 3.2 M ammonium sulphate. Source: Streptomyces lividans DSMZ 46482. UDP-glucose: oleandomycin β-glucosyltransferase; UDP-glucose: tylosin β-glucosyltransferase; UDP-glucose: erythromycin β-glucosyltransferase; Macrolide glycosyltransferase; Oleandomycin glycosyltransferase. Cat No: NATE-1214.
Oleandomycin glycosyltransferase from Streptomyces antibioticus, Recombinant
UDP glycosyltransferases (UGT) are a superfamily of enzymes that catalyzes the addition of the glycosyl group from a UTP-sugar to a small hydrophobic molecule. Group: Enzymes. Synonyms: UDP-glucose: oleandomycin β-glucosyltransferase; UDP-glucose: tylosin β-glucosyltransferase; UDP-glucose: erythromycin β-glucosyltransferase; Macrolide glycosyltransferase; Oleandomycin glycosyltransferase. Enzyme Commission Number: EC 2.4.1.-. Purity: > 95 % as judged by SDS-PAGE. Macrolide glycosyltransferase. Mole weight: 45383.9 Da. Storage: Store at 4°C (shipped at room temperature). Form: Supplied in 3.2 M ammonium sulphate. Source: Streptomyces antibioticus. UDP-glucose: oleandomycin β-glucosyltransferase; UDP-glucose: tylosin β-glucosyltransferase; UDP-glucose: erythromycin β-glucosyltransferase; Macrolide glycosyltransferase; Oleandomycin glycosyltransferase. Cat No: NATE-1221.
O-mycaminosyltylonolide 6-deoxyallosyltransferase
The enzyme participates in the biosynthetic pathway of the macrolide antibiotic tylosin, which is produced by several species of Streptomyces bacteria. Group: Enzymes. Synonyms: tylN (gene name). Enzyme Commission Number: EC 2.4.1.317. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2553; O-mycaminosyltylonolide 6-deoxyallosyltransferase; EC 2.4.1.317; tylN (gene name). Cat No: EXWM-2553.
Tilmicosin
Macrolide antibiotic structurally related to tylosin. Antibacterial. Group: Biochemicals. Alternative Names: 4A-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]tylosin; Antibiotic EL 870; EL 870; LY 177370; Micotil; Micotil 300; Pulmotil. Grades: Highly Purified. CAS No. 108050-54-0. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
tylactone mycaminosyltransferase
The enzyme participates in the biosynthetic pathway of the macrolide antibiotic tylosin, which is produced by several species of Streptomyces bacteria. Activity is significantly enhanced by the presence of an accessory protein encoded by the tylM3 gene. Group: Enzymes. Synonyms: tylM2 (gene name). Enzyme Commission Number: EC 2.4.1.316. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2552; tylactone mycaminosyltransferase; EC 2.4.1.316; tylM2 (gene name). Cat No: EXWM-2552.
Tylvalosin
Tylvalosin, a macrolide antibiotic, is active against S. aureus, E. coli, and P. multocidas with MICs of 2, 128, and 128 μg/mL, respectively. Tylvalosin (5 and 10 μg/mL) reduces LPS-induced production of proinflammatory cytokines, prostaglandin E2 (PGE2) and nitric oxide in RAW 264.7 cells. Preparations containing tylvalosin have been used for the treatment and metaphylaxis of enzootic pneumonia caused by M. hyopneumoniae in pigs. Synonyms: 3-Acetate 4B-(3-methylbutanoate)-tylosin; 3-O-Acetyl-4''-O-isovaleryltylosin; Acetylisovaleryltylosin; 3-Acetyl-4''-isovaleryltylosin; AIV-tylosin; Tylosin acetate isovalerte; Oxacyclohexadeca-11,13-diene-7-acetaldehyde, 4-(acetyloxy)-15-[[(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-[2,6-dideoxy-3-C-methyl-4-O-(3-methyl-1-oxobutyl)-α-L-ribo-hexopyranosyl]-3-(dimethylamino)-β-D-glucopyranosyl]oxy]-16-ethyl-5,9,13-trimethyl-2,10-dioxo-, (4R,5S,6S,7R,9R,11E,13E,15R,16R)-. Grades: ≥95%. CAS No. 63409-12-1. Molecular formula: C53H87NO19. Mole weight: 1042.25.
Tylvalosin
Tylvalosin is an anti-bacterial agent that is shown through study as a good inhibitor of gram-positive bacteria. Group: Biochemicals. Alternative Names: 3-Acetate 4B-(3-methylbutanoate)-tylosin; 3-O-Acetyl-4''-O-isovaleryltylosin; Acetyl isovaleryl tyl osin. Grades: Highly Purified. CAS No. 63409-12-1. Pack Sizes: 1mg. US Biological Life Sciences.
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