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| Product | Description | |
|---|---|---|
| tyrosinase | A type III copper protein found in a broad variety of bacteria, fungi, plants, insects, crustaceans, and mammals, which is involved in the synthesis of betalains and melanin. The enzyme, which is activated upon binding molecular oxygen, can catalyse both a monophenolase reaction cycle (reaction 1) or a diphenolase reaction cycle (reaction 2). During the monophenolase cycle, one of the bound oxygen atoms is transferred to a monophenol (such as L-tyrosine), generating an o-diphenol intermediate, which is subsequently oxidized to an o-quinone and released, along with a water molecule. The enzyme remains in an inactive deoxy state, and is restored to the active oxy state by the binding of a...oxidase; cresolase; monophenolase; tyrosine-dopa oxidase; monophenol monooxidase; monophenol dihydroxyphenylalanine:oxygen oxidoreductase; N-acetyl-6-hydroxytryptophan oxidase; monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase; o-diphenol:O2 oxidoreductase; phenol oxidase. Enzyme Commission Number: EC 1.14.18.1. CAS No. 9002-10-2. Tyrosinase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0963; tyrosinase; EC 1.14.18.1; 9002-10-2; monophenol monooxygenase; phenolase; monophenol oxidase; cresolase; monophenolase; tyrosine-dopa oxidase; monophenol monooxidase; monophenol dihydroxyphenylalanine |  |
| Tyrosinase (146-156) | A peptide fragment of Tyrosinase. Tyrosinase is a rate-limiting enzyme for controlling the production of melanin. It is found inside melanosomes which are synthesized in the skin melanocytes. In humans, the tyrosinase enzyme is encoded by the TYR gene. |  |
| Tyrosinase (206-214) (human) | Tyrosinase (206-214) (human), a tyrosinase epitope recognized by HLA-A24-restricted tumor-infiltrating lymphocytes (TIL), represents a reagent that can be used to generate melanoma-specific T cells for adoptive immunotherapy, as well as a peptide vaccine for patients with HLA-A24+ melanoma. Synonyms: H-Ala-Phe-Leu-Pro-Trp-His-Arg-Leu-Phe-OH; L-alanyl-L-phenylalanyl-L-leucyl-L-prolyl-L-tryptophyl-L-histidyl-L-arginyl-L-leucyl-L-phenylalanine; L-Alanyl-L-phenylalanyl-L-leucyl-L-prolyl-L-tryptophyl-L-histidyl-N5-(diaminomethylene)-L-ornithyl-L-leucyl-L-phenylalanine. Grades: ≥90%. CAS No. 166188-11-0. Molecular formula: C61H83N15O10. Mole weight: 1186.41. | |
| Tyrosinase (208-216) | A peptide fragment of Tyrosinase. Tyrosinase is a rate-limiting enzyme for controlling the production of melanin. It is found inside melanosomes which are synthesized in the skin melanocytes. In humans, the tyrosinase enzyme is encoded by the TYR gene. | |
| Tyrosinase (240-251) | Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and plays an important role in the melanogenesis and enzymatic browning. Grades: >95%. | |
| Tyrosinase-IN-12 | Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) is a potent, non-competitive tyrosinase inhibitor with an IC 50 value of 49.33 ± 2.64 μM and K i value of 31.25 ± 0.25 μM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) have the highest radical scavenging activity to reduce the production of reactive oxygen species ( ROS ) with an IC 50 value of 25.39 ± 0.77 μM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) can be used for anti-browning substances in the food and agricultural sectors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1860779-42-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-149404. |  |
| Tyrosinase, Mushroom | Tyrosinase (EC 1.14.18.1) (Polyphenol oxidase) is a rate-limiting enzyme that controls the production of melanin and is encoded by TYR gene. Tyrosinase is mainly found in melanosomes synthesized by skin melanocytes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Polyphenol oxidase. CAS No. 9002-10-2. Pack Sizes: 1 KU; 5 KU. Product ID: HY-125860. | |
| Tyrosinase precursor (1-9) | Tyrosinase precursor (1-9) is a 9-aa peptide. Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and plays an important role in the melanogenesis and enzymatic browning. | |
| Tyrosinase-related protein-2 (180-188) | Tyrosinase-related protein-2 (180-188) is amino acids 180 to 188 fragment of Tyrosinase-related protein-2. TRP2 peptide, also named L-dopachrome tautomerase, H-2KB or DCT, is an immunopotientor for Melanoma, Neoplasms and Glioma. | |
| [Asp371]-Tyrosinase (369-377), human | It is derived from tyrosinase, a peptide fragment that controls melanin production and has been used to develop tumor-targeted vaccines with mixed efficacy. Synonyms: Tyrosinase Fragment 369-377 human; CMM8; OCA1A; OCAIA; SHEP3; TYR; Tyr-Met-Asp-Gly-Thr-Met-Ser-Gln-Val; L-tyrosyl-L-methionyl-L-alpha-aspartyl-glycyl-L-threonyl-L-methionyl-L-seryl-L-glutaminyl-L-valine. Grades: ≥95%. CAS No. 168650-46-2. Molecular formula: C42H66N10O16S2. Mole weight: 1031.16. | |
| Native Mushroom Tyrosinase | Tyrosinase is a copper-containing oxidase, which has activity for both catechols and cresol. It is responsible for browning reactions. This enzyme is reported to have two binding sites for aromatic substrates and a different binding site for oxygen-copper. Tyrosinase is a copper-containing oxidase, which has activity for both catechols and cresol. it is responsible for browning reactions. the enzyme is reported to have two binding sites for aromatic substrates and a different binding site for oxygen-copper. the copper is probably cu (I), with inactivation involving oxidation to cu (II) ion. tyrosinase is a copper-containing oxidase, which has activity for both catechols and cres...; monophenol dihydroxyphenylalanine:oxygen oxidoreductase; N-acetyl-6-hydroxytryptophan oxidase; monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase; o-diphenol:O2 oxidoreductase; phenol oxidase. Enzyme Commission Number: EC 1.14.18.1. CAS No. 9002-10-2. Tyrosinase. Mole weight: 128 kDa by sedimentation velocity diffusion; 133 kDa by light-scattering measurements, and 119.5 kDa by electrophoresis. Activity: > 1000 unit/mg solid. Storage: -20°C. Form: lyophilized powder. Source: Mushroom. Tyrosinase; EC 1.14.18.1; 9002-10-2; monophenol monooxygenase; phenolase; monophenol oxidase; cresolase; monophenolase; tyrosine-dopa oxidase; monophenol monooxidase; monophenol dihydrox | |
| 2- (3- ( (t-Butyldimethylsilyl) oxy) butoxy) acetic Acid | 2- (3- ( (t-Butyldimethylsilyl) oxy) butoxy) acetic Acid is an intermediate in synthesizing Bis(2-?butoxyethyl) 2-?(3-?Hydroxybutoxy)?ethyl Phosphate Triester (B415220), a compound derived from 2-Butoxyethanol (B692895), which is a reagent in the synthesis of 4-butoxyethoxy-N-octadecyl-1,8-naphthalimide as a new fluorescent probe for the determination of proteins. Also used as a reagent in the synthesis of 4-hydroxybenzaldehyde derivatives as tyrosinase inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C12H26O4Si. US Biological Life Sciences. |  Worldwide |
| 2- (3- ( (t-Butyldimethylsilyl) oxy) butoxy) ethanol | 2- (3- ( (t-Butyldimethylsilyl) oxy) butoxy) ethanol is an intermediate in synthesizing Bis(2-?butoxyethyl) 2-?(3-?Hydroxybutoxy)?ethyl Phosphate Triester (B415220), a compound derived from 2-Butoxyethanol (B692895), which is a reagent in the synthesis of 4-butoxyethoxy-N-octadecyl-1,8-naphthalimide as a new fluorescent probe for the determination of proteins. Also used as a reagent in the synthesis of 4-hydroxybenzaldehyde derivatives as tyrosinase inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C12H28O3Si. US Biological Life Sciences. | Worldwide |
| 2-Amino-1- (4-tri fluoromethoxyphenyl) ethanone Hydrochloride | 2-Amino-1- (4-tri fluoromethoxyphenyl) ethanone Hydrochloride is a reagent for the preparation of 4-phenylimidazole-2-thiones as tyrosinase inhibitors, their pharmaceutical and cosmetics compositions for the treatment or the prevention of the pigmentary disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 1092390-14-1. Pack Sizes: 250mg, 1g. Molecular Formula: C9H8F3NO2; (HCl), Molecular Weight: 219.163646. US Biological Life Sciences. | Worldwide |
| 2-Butoxyethanol | 2-Butoxyethanol is a reagent in the synthesis of 4-butoxyethoxy-N-octadecyl-1,8-naphthalimide as a new fluorescent probe for the determination of proteins. Also used as a reagent in the synthesis of 4-hydroxybenzaldehyde derivatives as tyrosinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 111-76-2. Pack Sizes: 10ml, 25ml. Molecular Formula: C6H14O2. US Biological Life Sciences. | Worldwide |
| 2-Butoxyethanol-d4 | 2-Butoxyethanol-d4 is the isotope labelled analog of 2-Butoxyethanol; a reagent in the synthesis of 4-butoxyethoxy-N-octadecyl-1,8-naphthalimide as a new fluorescent probe for the determination of proteins. Also used as a reagent in the synthesis of 4-hydroxybenzaldehyde derivatives as tyrosinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1219803-96-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C6H10D4O2. US Biological Life Sciences. | Worldwide |
| 2-?(Chloromethyl)?-?5-?hydroxy-4H-?pyran-?4-?one | 2-?(Chloromethyl)?-?5-?hydroxy-4H-?pyran-?4-?one is an intermediate in synthesizing Allo Maltol (A546700), the esters of 5-hydroxy-2-methyl-4H-pyran-4-one are used as novel tyrosinase inhibitors for skin-lightening cosmetic compositions. Group: Biochemicals. Grades: Highly Purified. CAS No. 7559-81-1. Pack Sizes: 100mg, 250mg. Molecular Formula: C6H5ClO3, Molecular Weight: 160.56. US Biological Life Sciences. | Worldwide |
| 2-Hydroxy-4-methoxybenzaldehyde | 2-hydroxy-4-methoxybenzaldehyde is a potent tyrosinase inhibitor [1]. 2-Hydroxy-4-methoxybenzaldehyde, an isomer of Vanillin, could be used to synthesis Urolithin M7 [2]. Uses: Scientific research. Group: Natural products. CAS No. 673-22-3. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-N0445. | |
| 2-Ketoglutaric acid (standard) | 2-Ketoglutaric acid (Standard) is the analytical standard of 2-Ketoglutaric acid. This product is intended for research and analytical applications. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase ( IC 50 =15 mM) [1]. Uses: Scientific research. Group: Natural products. CAS No. 328-50-7. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-W013636R. | |
| 2-Methoxycinnamic acid | 2-Methoxycinnamic acid is a noncompetitive inhibitor of tyrosinase [1]. Uses: Scientific research. Group: Natural products. CAS No. 6099-3-2. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1386. | |
| 2-Propoxybenzoic Acid | 2-Propoxybenzoic Acid is a salicylic acid derivative used in the preparation of inhibitors of tyrosinase or hyaluronidase. 2-Propoxybenzoic Acid is a very potent inhibitior of collagen-induced aggregation of human platelets. Group: Biochemicals. Alternative Names: Salicylic Acid Propyl Ether; o-Propoxybenzoic Acid. Grades: Highly Purified. CAS No. 2100-31-4. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
| 3-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-1-butanol | 3-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-1-butanol is an intermediate in synthesizing Bis(2-?butoxyethyl) 2-?(3-?Hydroxybutoxy)?ethyl Phosphate Triester (B415220), a compound derived from 2-Butoxyethanol (B692895), which is a reagent in the synthesis of 4-butoxyethoxy-N-octadecyl-1,8-naphthalimide as a new fluorescent probe for the determination of proteins. Also used as a reagent in the synthesis of 4-hydroxybenzaldehyde derivatives as tyrosinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 68726-87-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C10H24O2Si. US Biological Life Sciences. | Worldwide |
| 3-?[[ (1, ?1-?Dimethylethyl) ?dimethylsilyl]?oxy]?-butanoic Acid Ethyl Ester | 3-?[[ (1, ?1-?Dimethylethyl) ?dimethylsilyl]?oxy]?-butanoic Acid Ethyl Ester is an intermediate in synthesizing Bis(2-?butoxyethyl) 2-?(3-?Hydroxybutoxy)?ethyl Phosphate Triester (B415220), a compound derived from 2-Butoxyethanol (B692895), which is a reagent in the synthesis of 4-butoxyethoxy-N-octadecyl-1,8-naphthalimide as a new fluorescent probe for the determination of proteins. Also used as a reagent in the synthesis of 4-hydroxybenzaldehyde derivatives as tyrosinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 81327-43-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C12H26O3Si. US Biological Life Sciences. | Worldwide |
| 3',4'-Dihydroxyacetophenone | 3',4'-Dihydroxyacetophenone (3,4-DHAP), isolated from Picea Schrenkiana Needles exhibits a strong suppressive action against tyrosinase activity, with an IC 50 of 10 μM. 3',4'-Dihydroxyacetophenone (3,4-DHAP) is a vasoactive agent and antioxidant [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 3,4-DHAP. CAS No. 1197-09-7. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N1775. | |
| 3,4-Dihydroxybenzylamine hydrobromide | 3,4-Dihydroxybenzylamine hydrobromide (NSC 263475 hydrobromide) is an improved dopamine analog cytotoxic and inhibits DNA polymerase activity in melanoma cells [2]. 3,4-Dihydroxybenzylamine hydrobromide (NSC 263475 hydrobromide) displays growth inhibitory activity in melanoma cell lines with varying degrees of tyrosinase activity [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 263475 hydrobromide. CAS No. 16290-26-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N3023. | |
| 3,4-Dihydroxybenzylamine hydrobromide | 3,4-Dihydroxybenzylamine hydrobromide (NSC 263475 hydrobromide) is an improved dopamine analog cytotoxic and inhibits DNA polymerase activity in melanoma cells. 3,4-Dihydroxybenzylamine hydrobromide (NSC 263475 hydrobromide) displays growth inhibitory activity in melanoma cell lines with varying degrees of tyrosinase activity. Group: Inhibitors. CAS No. 16290-26-9. Molecular formula: C7H10BrNO2. Mole weight: 220.06. Appearance: Solid. Purity: ≥95.0%. Canonical SMILES: [H]Br.NCC1=CC(O)=C(O)C=C1. Catalog: ACM16290269. |  |
| 3,4-Dimethoxyphenol | 3,4-Dimethoxyphenol is a plant-derived phenylpropanoid compound and can use as a whitening agent in cosmetics. 3,4-Dimethoxyphenol has tyrosinase -inhibiting activity [1]. 3,4-Dimethoxyphenol has potent antioxidant effect isolated from the bacterial fermentation broth [2]. Uses: Scientific research. Group: Natural products. CAS No. 2033-89-8. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N1780. | |
| 3-Fluorobenzaldehyde | 3-Fluorobenzaldehyde is a monofluorinated aromatic aldehyde with potential antimicrobial activity. 3-Fluorobenzaldehyde showed inhibitory effects on the activity of mushroom tyrosinase. Group: Biochemicals. Alternative Names: 3-Fluoro Benzene carboxaldehyde; 3-Fluorophenylcarboxalde hyde; NSC 66830; m-Fluorobenzaldehyde. Grades: Highly Purified. CAS No. 456-48-4. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
| 3-O-Ethyl-L-ascorbic acid | 3-O-Ethyl-L-ascorbic acid, a stable vitamin C derivative, is a cosmetic tyrosinase tnhibitor with a whitening capacity. 3-O-Ethyl-L-ascorbic acid also has antioxidant abilities [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 86404-04-8. Pack Sizes: 1 g; 5 g. Product ID: HY-W003607. | |
| 4- (2-Oxiranylmethoxy) benzoic Acid Methyl Ester | Intermediate in the production of tyrosinase-inhibitors used in skin lightening cosmetics. Group: Biochemicals. Alternative Names: Methyl 4-(2,3-Epoxypropoxy)benzoate. Grades: Highly Purified. CAS No. 5535-3-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 4-Butylresorcinol | 4-Butylresorcinol is a phenol derivative which can inhibit tyrosinase with IC 50 of 11.27 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Butylresorcinol. CAS No. 18979-61-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-107369. | |
| 4-Butylresorcinol | 4-Butylresorcinol is a potent inhibitor of tyrosinase and is used in cosmetics as a depigmenting agent. Synonyms: 4-n-Butylresorcinol, Rucinol; 4-butylbenzene-1,3-diol. Grades: ≥98%. CAS No. 18979-61-8. Molecular formula: C10H14O2. Mole weight: 166.22. | |
| 4-Chlorocinnamic acid | 4-Chlorocinnamic acid has inhibitory effects on tyrosinase. 4-Chlorocinnamic acid has antibacterial activity. 4-Chlorocinnamic acid also inhibits Colletotrichum gloeosporioides growth [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1615-02-7. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-Y0729. | |
| 4-Cyanobenzoic Acid | An inhibitor. The studies show that 4-cyanobenzaldehyde and 4-cyanobenzoic acid can inhibit both the monophenolase activity and the diphenolase activity of mushroom tyrosinase. Group: Biochemicals. Alternative Names: p-Cyanobenzoic Acid; 4-Carboxybenzonitrile. Grades: Highly Purified. CAS No. 619-65-8. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 4-Ethylresorcinol | 4-Ethylresorcinol, a derivative of resorcinol, can act as substrates of tyrosinase. 4-Ethylresorcinol possess hypopigmentary effects. 4-Ethylresorcinol attenuates mRNA and protein expression of tyrosinase-related protein (TRP)-2, and possessed antioxidative effect by inhibiting lipid peroxidation [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 2896-60-8. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W015782. | |
| 4-Fluorobenzaldehyde | 4-Fluorobenzaldehyde is a fluorinated benzaldehyde with inhibitory activity of mushroom tyrosinase. 4-Fluorobenzaldehyde is commonly used as a synthetic intermediate in the preparation of pharmaceutical compounds. Group: Biochemicals. Alternative Names: NSC 68095; p-Fluorobenzaldehyde; p-Fluoro Benzene carboxaldehyde. Grades: Highly Purified. CAS No. 459-57-4. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 4-Isopropylbenzoic Acid | 4-Isopropylbenzoic acid, an aromatic monoterpenoid, is isolated from the stem bark of Bridelia retusa. 4-Isopropylbenzoic acid exhibits antifungal activities. 4-Isopropylbenzoic acid is also a reversible and uncompetitive inhibitor of mushroom tyrosinase. Group: Inhibitors. CAS No. 536-66-3. Molecular formula: C10H12O2. Mole weight: 164.2. Appearance: Solid. Purity: 0.97. Canonical SMILES: C1=CC(=CC=C1C(C)C)C(O)=O. Catalog: ACM536663. | |
| 4-Isopropylcatechol | 4-Isopropylcatechol is a potent and irreversible cutaneous depigmenting agent. 4-Isopropylcatechol significantly inhibits protein biosynthesis in mouse melanoma cells containing high levels of tyrosinase. 4-Isopropylcatechol can be use to study hyperpigmentation of skins [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-IPC. CAS No. 2138-43-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139430. | |
| 5-Hydroxyindole | 5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptophan. 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets. Group: Biochemicals. Alternative Names: 1H-Indol-5-ol; Indol-5-ol; 5-Hydroxy-1H-indole; NSC 87503. Grades: Highly Purified. CAS No. 1953-54-4. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 5-Methylresorcinol monohydrate | 5-Methylresorcinol monohydrate (Orcinol monohydrate) is a tyrosinase inhibitor. 5-Methylresorcinol monohydrate shows cytotoxicity. 5-Methylresorcinol monohydrate also is an oral active and cross the blood-brain barrier anxiolytic agent [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Orcinol monohydrate. CAS No. 6153-39-5. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W015715. | |
| Acetyl Hexapeptide-1 | Acetyl Hexapeptide-1, also known as Melitane, is a biomimetic peptide antagonist of the α-MSH (α-Melanocyte-Stimulating Hormone). It stimulates tyrosinase activity, melanin synthesis and melanocyte dendricity, and protects DNA damage caused by UV exposure. Synonyms: Melitane. Grades: 98%. CAS No. 448944-47-6. Molecular formula: C43H59N13O7. Mole weight: 870. | |
| Aloesin | Aloesin (Aloeresin) is a tyrosinase inhibitor, and shows anti-inflammatory activity, ultraviolet protection, and antibacterium effects. Aloesin can induce apoptosis and be used in ovarian cancer research [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Aloeresin. CAS No. 30861-27-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2460. | |
| Aloesin | Aloesin is an aloe chromone that exhibits competitive inhibitory effects against tyrosinase, an enzyme responsible for catalyzing phenol oxidation in plants. Studies have shown that aloesin modulates melanogenesis and dispalys anti-inflammatory effects in rats. Synonyms: Aloe resin B; 8-b-D-Glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)-4H-1-benzopyran-4-one. CAS No. 30861-27-9. Molecular formula: C19H22O9. Mole weight: 394.37. | |
| α-Arbutin | α-Arbutin (4-Hydroxyphenyl α-D-glucopyranoside) is a tyrosinase inhibitor, which is used as an effective skin whiteners. α-Arbutin is promising for research of various diseases such as hyperpigmentation disorders, types of cancers, central nervous system disorders, osteoporosis, diabetes [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: 4-Hydroxyphenyl α-D-glucopyranoside. CAS No. 84380-01-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N3002. | |
| alpha-Arbutin | Hydroquinone derivative isolated from the leaves of the bearberry shrub, cranberry, blueberry, some mushrooms, and most types of pears. It inhibits tyrosinase and thus prevents the formation of melanin. Arbutin is therefore used as a skin-lightening agent. Categories: alpha Arbutin. |  United States and all of its trading partners.. |
| Alpha-arbutin | Alpha-arbutin. Synonyms: 4-Hydroxyphenyl α-D-glucopyranoside, Hydroquinone O-α-D-glucopyranoside. CAS No. 84380-01-8. Pack Sizes: 1 kg. Product ID: CDC10-0374. Molecular formula: C12H16O7. Category: Cosmetic Surfactants. Product Keywords: Cosmetic Ingredients; Cosmetic Surfactants; Alpha-arbutin; CDC10-0374; 84380-01-8; C12H16O7; 4-Hydroxyphenyl α-D-glucopyranoside, Hydroquinone O-α-D-glucopyranoside; MFCD09838262; 84380-01-8. Grade: Analytical standard. Purity: 0.995. Color: White. Physical State: Powder. Solubility: DMSO (Slightly), Methanol (Slightly). Quality Level: 100. Storage: 2-8°C. Application: Personal care. Boiling Point: 561.6±50.0 °C(Predicted). Melting Point: 195-196°C. Density: 1.556±0.06 g/cm3(Predicted). Product Description: α-Arbutin is a glycosylated hydroquinone and an anomer of naturally occurring arbutin. It is a potent inhibitor of tyrosinase, a vital enzyme involved in epidermal melanin biosynthesis. α-Arbutin finds extensive application as a powerful skin-lightening agent in cosmetic industries. |  |
| Anemonin | Anemonin is isolated from the dry root of Pulsatilla chinensis(B ge.) Regel. It was shown to regulate tyrosinase-related proteins and mRNA in human melanocytes. Uses: Antineoplastic, antibacterial agent. Synonyms: 1,7-Dioxadispiro[4.0.4.2]dodeca-3,9-diene-2,8-dione. Grades: >98%. CAS No. 90921-11-2. Molecular formula: C10H8O4. Mole weight: 192.17. | |
| Arbutin | Arbutin (β-Arbutin) is a competitive inhibitor of tyrosinase , with K i app values of 1.42 mM for monophenolase; 0.9 mM for diphenolase. Arbutin is also used as depigmenting agents [1]. Arbutin is a natural polyphenol isolated from the bearberry plant Arctostaphylos uvaursi , possesses with anti-oxidant, anti-inflammatory and anti-tumor properties [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: β-Arbutin. CAS No. 497-76-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g; 25 g; 50 g. Product ID: HY-N0192. | |
| Arbutin | Arbutin is a natural active substance derived from green plants. It combines the "green plant, safe and reliable" and "high-efficiency discoloration" into a skin decolorizing component, which can quickly penetrate into the skin without affecting cell proliferation. At the same time, it can effectively inhibit the activity of tyrosinase in the skin, block the formation of melanin, and directly combine with tyrosinase to accelerate the decompositio;n and excretion of melanin, thereby reducing skin pigmentation, eliminating pigmentation and Freckles, and do not produce toxic, irritating, sensitizing and other side effects on melanocytes, as well as bactericidal and anti-inflammatory effects. Group: Material of cosmetics. Alternative Names: 4-Hydroxyphenyl-beta-D-glucopyranosid. CAS No. 497-76-7. Molecular formula: C12H16O7. Mole weight: 272.25. Appearance: Solid. Purity: 0.98. IUPACName: (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol. Canonical SMILES: C1=CC(=CC=C1O)OC2C(C(C(C(O2)CO)O)O)O. Density: 1.3582 g/cm³. ECNumber: 207-850-3. Catalog: ACM497767. | |
| Arbutin | Arbutin. Synonyms: Hydroquinone-Beta-D-glucopyranoside. CAS No. 497-76-7. Product ID: CDC10-0032. Molecular formula: C12H16O7. Category: Antioxidant Cosmetic Chemicals. Product Keywords: Cosmetic Ingredients; Antioxidant Cosmetic Chemicals; Arbutin; CDC10-0032; 497-76-7; C12H16O7; Hydroquinone-Beta-D-glucopyranoside; 207-850-3; MFCD00016915; 497-76-7. Purity: ≥98%. Color: White. EC Number: 207-850-3. Physical State: Powder. Solubility: H2O: 50 mg/mL hot, clear. Quality Level: 200. Storage: Inert atmosphere,Room Temperature. Application: Arbutin, a glycosylated hydroquinone, is used in studies on melanin biosynthesis and as an inhibitor to identify, differentiate and characterize tyrosinase(s). Boiling Point: 375.31°C (rough estimate). Melting Point: 195 °C. Product Description: Arbutin is a derivative of hydroquinone used in skin-whitening ingredients. It is reported to inhibit the activity of tyrosinase, which is a key enzyme for melanin biosynthesis. This acts to effectively prevent the anomalous increase of melanin which is blamed for age or sun spots and freckles. | |
| Arbutin (Standard) | Arbutin (Standard) is the analytical standard of Arbutin. This product is intended for research and analytical applications. Arbutin (β-Arbutin) is a competitive inhibitor of tyrosinase, with Kiapp values of 1.42 mM for monophenolase; 0.9 mM for diphenolase. Arbutin is also used as depigmenting agents [1]. Arbutin is a natural polyphenol isolated from the bearberry plant Arctostaphylos uvaursi, possesses with anti-oxidant, anti-inflammatory and anti-tumor properties [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 497-76-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0192R. | |
| Azo-Resveratrol | Azo-Resveratrol is a Resveratrol analog that acts as a tyrosinase inhibitor. Synonyms: (E)-5-((4-hydroxyphenyl)diazenyl)benzene-1,3-diol. Grades: >98%. CAS No. 1393556-48-3. Molecular formula: C12H10N2O3. Mole weight: 230.22. | |
| Benzylideneacetone | Benzylideneacetone (Benzalacetone) is an orally active antibiotic , tyrosinase inhibitor, phospholipase A 2 inhibitor, and immunosuppressant. Benzylideneacetone has antibacterial activity against some gram-negative plant-pathogenic bacteria. Benzylideneacetone can also be used in the synthesis of chemicals and drugs, and as a flavoring additive for some foods [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Benzalacetone. CAS No. 122-57-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W012595. | |
| beta-Arbutin | Hydroquinone derivative isolated from the leaves of the bearberry shrub, cranberry, blueberry, some mushrooms, and most types of pears. It inhibits tyrosinase and thus prevents the formation of melanin. Arbutin is therefore used as a skin-lightening agent. Categories: beta Arbutin. | United States and all of its trading partners.. |
| β-Tocopherol | β-Tocopherol is an analogue of vitamin E, exhibits antioxidant properties. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol also can prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 16698-35-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-133680. | |
| Cardanol monoene | Cardanol monoene is also known as anacardic acid (C15:1). It inhibits the linoleic acid peroxidation catalyzed by soybean lipoxygenase-1 with an IC50 of 6.8 mM. Cardanol monoene is also a phenol found in cashew nut shell liquid that reversibly inhibits tyrosinase with an IC50 value of 56 μM in vitro. It halts the cell cycle at the S phase and inhibits proliferation dose- and time-dependently in M14 melanoma cells (IC50s = 23.15 and 12.30 μM after 24 and 48 hours of treatment, respectively). A mixture of cardanol mono-, di-, and triene is used to synthesize cardanol-metal complexes that inhibit uropathogenic E. coli biofilm formation. Synonyms: Cardanol C15:1; 6[8'(Z)-pentadecenyl]salicylic acid. Grades: ≥98%. CAS No. 501-26-8. Molecular formula: C21H34O. Mole weight: 302.5. | |
| catechol oxidase | A type 3 copper protein that catalyses exclusively the oxidation of catechol (i.e., o-diphenol) to the corresponding o-quinone. The enzyme also acts on a variety of substituted catechols.It is different from tyrosinase, EC 1.14.18.1, which can catalyse both the monooxygenation of monophenols and the oxidation of catechols. Group: Enzymes. Synonyms: diphenol oxidase; o-diphenolase; polyphenol oxidase; pyrocatechol oxidase; dopa oxidase; catecholase; o-diphenol:oxygen oxidoreductase; o-diphenol oxidoreductase. Enzyme Commission Number: EC 1.10.3.1. CAS No. 9002-10-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0475; catechol oxidase; EC 1.10.3.1; 9002-10-2; diphenol oxidase; o-diphenolase; polyphenol oxidase; pyrocatechol oxidase; dopa oxidase; catecholase; o-diphenol:oxygen oxidoreductase; o-diphenol oxidoreductase. Cat No: EXWM-0475. | |
| Cis-Mulberroside A | cis-Mulberroside A (Mulberroside D) is the cis-isomer of Mulberroside A. Mulberroside A is one of the main bioactive constituent in mulberry (Morus alba L.). Mulberroside A decreases the expressions of TNF-α, IL-1β, and IL-6 and inhibits the activation of NALP3, caspase-1, and NF-κB and the phosphorylation of ERK, JNK, and p38, exhibiting anti-inflammatory and anti-apoptotic effects. Mulberroside A shows inhibitory activity against mushroom tyrosinase with an IC50 of 53.6 μM. Group: Inhibitors. CAS No. 166734-06-1. Molecular formula: C26H32O14. Mole weight: 568.52. Appearance: Powder. Purity: 0.98. IUPACName: (2S, 3R, 4S, 5S, 6R)-2-[3-hydroxy-4-[ (Z)-2-[3-hydroxy-5-[ (2S, 3R, 4S, 5S, 6R)-3, 4, 5-trihydroxy-6- (hydroxymethyl)oxan-2-yl]oxyphenyl]ethenyl]phenoxy]-6- (hydroxymethyl)oxane-3, 4, 5-triol. Canonical SMILES: C1=CC (=C (C=C1OC2C (C (C (C (O2)CO)O)O)O)O)C=CC3=CC (=CC (=C3)OC4C (C (C (C (O4)CO)O)O)O)O. Catalog: ACM166734061. | |
| Decanoic acid | Decanoic acid is a key component of the medium-chain triglyceride (MCT) found in coconut oil. Decanoic acid is a brain-penetrant and non-competitive inhibitor of AMPA receptor showing antiseizure activity in rats. Decanoic acid reduces tyrosinase activity and inhibits melanosome maturation. Decanoic acid suppresses the phosphorylation of c-Met and induced apoptosis in hepatocellular carcinoma (HCC) cells by inhibiting the expression of various oncogenic proteins, which is promising for research in the field of mTORC1 signaling, HCC and epilepsy [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 334-48-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W015309. | |
| Decapeptide-12 | Decapeptide-12 reversibly binds to tyrosinase, an enzyme found in a number of different pigment-producing cells. It prevents tyrosinase from catalyzing the oxidation of phenols, the first step in melanin production. Synonyms: L-Tyrosyl-L-arginyl-L-seryl-L-arginyl-L-lysyl-L-tyrosyl-L-seryl-L-seryl-L-tryptophyl-L-tyrosine. Grades: 98%. CAS No. 137665-91-9. Molecular formula: C65H90N18O17. Mole weight: 1395.5. | |
| Dehydroanonaine | Dehydroanonaine is a dietary supplement that is used for the treatment of pain. It inhibits the activity of creatine kinase, which is an enzyme that breaks down adenosine triphosphate (ATP) to produce energy. Dehydroanonaine also inhibits acetate extract from fatty acids and has been shown to have an inhibitory effect on tyrosinase, an enzyme involved in the production of melanin. The effective dose for dehydroanonaine is not known. Dehydroanonaine can be used cosmetically by increasing the skin's elasticity and reducing wrinkles and age spots. Group: Other alkaloids. CAS No. 41679-82-7. Molecular formula: C17H13NO2. Mole weight: 263.29 g/mol. Canonical SMILES: C1CNC2= CC3= CC= CC= C3C4= C2C1= CC5= C4OCO5. Catalog: ACM41679827. | |
| Dehydroroemerine | Dehydroroemerine is a cyclic peptide that inhibits the enzyme Cox-2, which is involved in the production of inflammatory prostaglandins. This drug has been shown to have anti-inflammatory effects and has been used as a food additive in Japan. Dehydroroemerine has also been reported to have anti-inflammatory properties, which are demonstrated by its ability to inhibit tyrosinase activity. The effective dose of this drug is not yet known; however, it can be administered orally at a concentration of 3 mg/kg body weight. This drug may be used for the treatment of pain models. Group: Other alkaloids. CAS No. 36285-03-7. Molecular formula: C18H15NO2. Mole weight: 277.32 g/mol. Canonical SMILES: CN1CCC2=CC3=C (C4=C2C1=CC5=CC=CC=C54)OCO3. Catalog: ACM36285037. | |
| Deoxyarbutin | Deoxyarbutin is an orally active tyrosinase inhibitor that can promote apoptosis of melanoma cells, enhance the vitality of mouse acinar cells, and has skin whitening and anti-tumor activity [1][2][3]. Uses: Scientific research. Group: Natural products. CAS No. 53936-56-4. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-B1461. | |
| D-Tyrosine | D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 556-02-5. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-Y0444. | |
| (±)-Eriodictyol | (±)-Eriodictyol ((±)-Huazhongilexone), a flavonoid, is a potent melanogenesis inhibitor with an IC 50 of 48 μM. (±)-Eriodictyol suppresses tyrosinase, TRP-1, and TRP-2 mRNA expression. (±)-Eriodictyol has strong anti-plasmin activities [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Huazhongilexone; Dihydroluteolin. CAS No. 4049-38-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0637A. | |
| Glycolic acid | Glycolic acid is an inhibitor of tyrosinase , suppressing melanin formation and lead to a lightening of skin colour. Uses: Scientific research. Group: Natural products. Alternative Names: Hydroxyethanoic acid. CAS No. 79-14-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W015967. | |
| Gnetol | Gnetol is a phenolic compound isolated from the root of Gnetum montanum. Gnetol potently inhibits COX-1 (IC50 of 0.78 μM) and HDAC. Gnetol is a potent tyrosinase inhibitor with an IC50 of 4.5 μM for murine tyrosinase and suppresses melanin biosynthesis. Gnetol has antioxidant, antiproliferative, anticancer and hepatoprotective activity. Gnetol also possesses concentration-dependent α-Amylase, α-glucosidase, and adipogenesis activities. Group: Inhibitors. Alternative Names: 2-[(1E)-2-(3,5-Dihydroxyphenyl)ethenyl]-1,3-benzenediol;Gnetol. CAS No. 86361-55-9. Molecular formula: C14H12O4. Mole weight: 244.2. Appearance: Powder. Purity: 0.98. IUPACName: 2-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,3-diol. Canonical SMILES: C1=CC (=C (C (=C1)O)C=CC2=CC (=CC (=C2)O)O)O. Catalog: ACM86361559. | |
| Hydrolyzed Pearl | Hydrolyzed pearl provides excellent anti-aging and toning properties. It reduces the activation of tyrosinase and free radicals, retaining water in the epidermis, stimulating collagen production and preventing the formation of enzymes responsible for degradation of elastic fibers. Uses: Anti-aging and anti-wrinkle products, serums, moisturizers and after-shaves products, facial toners and micellar waters. Group: Skin actives. CAS No. 7732-18-5 / 56-81-5 / 532-32-1 / 24634-61-5 / 90-80-2 / 299-28-5. Catalog: CI-SC-0773. | |
| Isobutylamido thiazolyl resorcinol | Isobutylamido thiazolyl resorcinol is a Tyrosinase inhibitor that can prevent UV-induced pigmentation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1428450-95-6. Pack Sizes: 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W251181. | |
| Kojibiose | Kojibiose, a remarkable biomedicine, stands as a powerful solution for an array of dermatological afflictions. Renowned for its profound capacity to impede tyrosinase activity, this therapeutic wonder effectively combats skin pigmentation maladies like melasma and hyperpigmentation. Synonyms: 2-O-(a-D-Glucopyranosyl)-a-D-glucopyranose; Glc-a-1,2-Glc; D-Glucose, 2-O-α-D-glucopyranosyl-; 2-O-α-D-Glucopyranosyl-D-glucose. Grades: ≥95%. CAS No. 2140-29-6. Molecular formula: C12H22O11. Mole weight: 342.30. | |
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