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| Product | Description | |
|---|---|---|
| Tyrosine kinase inhibitor | It is a Tyrosine kinase inhibitor. Synonyms: Tyrosine kinase inhibitor; MDK-0264; MDK0264; MDK 0264; B-Raf IN, B-Raf Inhibitor. Grades: >98%. CAS No. 1021950-26-4. Molecular formula: C31H31FN6O5. Mole weight: 586.61. |  |
| Tyrosine kinase inhibitor | Tyrosine kinase inhibitor is a potent tyrosine kinase inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1021950-26-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-10421. |  |
| Tyrosine Kinase Inhibitor Library | A unique collection of 746 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Targets include c-Kit, c-Met, EGFR, FGFR, SRC, JAK, SYK, Btk, Bcr-Abl, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2200. Categories: Tyrosine Kinase Inhibitor Libraries. |  |
| BMP Inhibitor III, LDN-212854 (Abl Inhibitor V, LDN212854, Bone Morphogenetic Protein Inhibitor III, PDGFR Tyrosine Kinase Inhibitor XXIV, RIP2 Inhibitor I, RIPK2 Inhibitor I, 5-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline) | A cell-permeable pyrazolopyrimidinyl quinoline that is superior to Dorsomorphin and DMH1 as an ATP-site-targeting, ALK1/2 inhibitor (IC50 = 2.40 and 1.30nM, respectively; [ATP] = 6uM) with respect to both potency and selectivity over ALK3/4/5 (IC50 = 0.858, 2.133, and 9.276uM, respectively). Also a potent RIPK2 inhibitor (IC50 = 6nM) with reduced potency against ABL1/c-abl, PDGFR-beta, ALK3, and PDGFR-alpha (IC50 = 40, 68, 85.8, and 650nM, respectively) and little inhibitory activity toward a panel of more than 190 kinases. Effectively inhibits ALK2- and ALK3-mediated C2C12 osteogenic differentiation (IC50 = 10 and 40.5nM, respectively) in vitro and prevents constitutively active ALK2 Q207D mutant-induced heterotopic ossification in mice (6mg/kg/12h via i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??N?. US Biological Life Sciences. |  Worldwide |
| cFMS Receptor Tyrosine Kinase Inhibitor - CAS 870483-87-7 | The cFMS Receptor Tyrosine Kinase Inhibitor, also referenced under CAS 870483-87-7, controls the biological activity of cFMS. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. |  |
| Emodin, p56lck Tyrosine Kinase Inhibitor | Occurs mostly as the rhamnoside (see Frangulin) in rhubarb root. Cathartic. Cell-permeable. A naturally occurring anthraquinone that displays a range of biological activities including anti- inflammatory, anti-tumor and neuroprotective effects. Acts as a potent p56lck tyrosine kinase inhibitor (IC50 = 18.5uM). Group: Biochemicals. Alternative Names: 1,3,8-Trihydroxy-6-methyl-9,10-anthracenedione; 1,6,8-Trihydroxy-3-methylanthraquinone; 4,5,7-Trihydroxy-2-methylanthraquinone; Archin; Emodin; Emodol; Frangula Emodin; Frangulic Acid; NSC 408120; NSC 622947; Rheum Emodin; Schuttgelb. Grades: Highly Purified. CAS No. 518-82-1. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C??H??O?, Molecular Weight: 270.24. US Biological Life Sciences. | Worldwide |
| FGF Receptor Tyrosine Kinase Inhibitor - CAS 192705-79-6 | The FGF Receptor Tyrosine Kinase Inhibitor, also referenced under CAS 192705-79-6, controls the biological activity of FGF Receptor Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| FGF Receptor Tyrosine Kinase Inhibitor IV, NP603 - CAS 949164-80-1 | The FGF Receptor Tyrosine Kinase Inhibitor IV, NP603 controls the biological activity of FGF Receptor Tyrosine KInase. Primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| FGF/VEGF Receptor Tyrosine Kinase Inhibitor, PD173074 - CAS 219580-11-7 | The FGF/VEGF Receptor Tyrosine Kinase Inhibitor, PD173074 controls the biological activity of FGF/VEGF Receptor Tyrosine Kinase. Primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| InSolution cFMS Receptor Tyrosine Kinase Inhibitor | The cFMS Receptor Tyrosine Kinase Inhibitor controls the biological activity of cFMS Receptor Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Met/Flt-3/VEGFR2 Tyrosine Kinase Inhibitor - CAS 888719-03-7 | The Met/Flt-3/VEGFR2 Tyrosine Kinase Inhibitor controls the biological activity of Met/Flt-3/VEGFR2 Tyrosine Kinase. Primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| PD 173074 (PD173074, UNII-A4TLL8634Y, FGF/VEGF Receptor Tyrosine Kinase Inhibitor) | PD 173074 (PD173074, UNII-A4TLL8634Y, FGF/VEGF Receptor Tyrosine Kinase Inhibitor). Group: Biochemicals. Alternative Names: 1-tert-butyl-3-[2-[4- (diethylamino) butylamino]-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]urea. Grades: Highly Purified. CAS No. 219580-11-7. Pack Sizes: 25mg. Molecular Formula: C28 H41 N7O3 , Molecular Weight: 523.7. US Biological Life Sciences. | Worldwide |
| PDGFR Tyrosine Kinase Inhibitor II - CAS 249762-74-1 | The PDGFR Tyrosine Kinase Inhibitor II, also referenced under CAS 249762-74-1, controls the biological activity of PDGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| PDGFR Tyrosine Kinase Inhibitor V - CAS 347155-76-4 | The PDGFR Tyrosine Kinase Inhibitor V, also referenced under CAS 347155-76-4, controls the biological activity of PDGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| PDGFR Tyrosine Kinase Inhibitor VII - CAS 251356-45-3 | The PDGFR Tyrosine Kinase Inhibitor VII, also referenced under CAS 251356-45-3, controls the biological activity of PDGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| PDGFR Tyrosine Kinase Inhibitor VI, SU6668 - CAS 210644-62-5 | The PDGFR Tyrosine Kinase Inhibitor VI, SU6668, also referenced under CAS 210644-62-5, controls the biological activity of PDGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Syk Inhibitor V ( (S) -2- (2- ( (3, 5-dimethylphenyl) amino) pyrimidin-4-yl) -N- (1-hydroxypropan-2-yl) -4-methylthiazole-5-carboxamide, Spleen Tyrosine Kinase Inhibitor) | A cell-permeable, 4-thiazolyl-2-phenylaminopyrimidine compound that acts as a potent, reversible, and ATP-competitive inhibitor of spleen tyrosine kinase (Syk) (Ki=9nM). Exhibits excellent selectivity over Cdk2 (Ki=3.33uM), ROCK (Ki=2.3uM), Src (Ki=3.33uM), and ZAP70 (Ki=240nM). Shown to inhibit mast cell degranulation (IC50=70nM) that is commonly observed in asthma and other allergic diseases. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg. Molecular Formula: C??H??N?O?S, Molecular Weight: 397.5. US Biological Life Sciences. | Worldwide |
| VEGFR2 Kinase Inhibitor VII, SKLB1002 (VEGFR Tyrosine Kinase Inhibitor XXXV, 6,7-Dimethoxy-4-(5-methyl-1,3,4-thiadiazol-2-ylthio)quinazoline, Vascular Endothelial Growth Factor Receptor 2 Kinase Inhibitor VII) | A cell-permeable quinazoline that acts as a potent, ATP-binding site-targeting, VEGFR2-selective inhibitor (IC50=32nM), while exhibiting much reduced or little activity against 16 other kinases. An effective antiangiogenesis agent (98% inhibition of HUVEC tube formation at 10uM; 80% inhibition of zebrafish embryos intersegmental vessel growth at 2.5uM) that significantly suppresses SW620- and HepG2-derived tumor growth in mice (by 72% and 63%, respectively, in 18 days; 100mg/kg/day; i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| VEGFR/Tie-2/PDGFR Tyrosine Kinase Inhibitor | The VEGFR/Tie-2/PDGFR Tyrosine Kinase Inhibitor controls the biological activity of VEGFR/Tie-2/PDGFR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| VEGFR Tyrosine Kinase Inhibitor II | VEGFR tyrosine kinase inhibitor II is a pyridinyl-anthranilamide compound that potently inhibits the kinase activities of VEGFR2 (KDR), VEGFR1 (FLT1), and c-Kit (IC50 = 20, 180, and 240 nM, respectively). It is potential for cancer treatment for its inhibitory effect of tumor induced angiogenesis. Synonyms: N-(4-Chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide. Grades: ≥98%. CAS No. 269390-69-4. Molecular formula: C19H16ClN3O. Mole weight: 337.8. | |
| VEGFR Tyrosine Kinase Inhibitor II - CAS 269390-69-4 | The VEGFR Tyrosine Kinase Inhibitor II, also referenced under CAS 269390-69-4, controls the biological activity of VEGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| VEGFR Tyrosine Kinase Inhibitor V | The VEGFR Tyrosine Kinase Inhibitor V controls the biological activity of VEGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| VEGFR Tyrosine Kinase Inhibitor VI, AAL-993 - CAS 269390-77-4 | The VEGFR Tyrosine Kinse Inhibitor VI, ALL-993, also referenced under CAS 269390-77-4, controls the biological activity of VEGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Cancer applications. Group: Fluorescence/luminescence spectroscopy. | |
| 1-(1,1-Dimethylethyl)-4-iodo-2,5-dimethoxy-benzene | 1-(1,1-Dimethylethyl)-4-iodo-2,5-dimethoxy-benzene is an intermediate used to prepare heterocyclic tyrosine kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 91562-20-8. Pack Sizes: 10mg, 100mg. Molecular Formula: C12H17IO2, Molecular Weight: 320.17. US Biological Life Sciences. | Worldwide |
| 1-(1,1-Dimethylethyl)-4-iodo-2,5-dimethoxy-benzene-d6 | 1-(1,1-Dimethylethyl)-4-iodo-2,5-dimethoxy-benzene-d6 is labelled 1-(1,1-Dimethylethyl)-4-iodo-2,5-dimethoxy-benzene which is an intermediate used to prepare heterocyclic tyrosine kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C12H11D6IO2, Molecular Weight: 326.2. US Biological Life Sciences. | Worldwide |
| 1,2,3,4,5,6-Hexabromocyclohexane | 1,2,3,4,5,6-Hexabromocyclohexane is a potent inhibitor of JAK2 tyrosine kinase autophosphorylation. It inhibits JAK2 activation, and reduces growth hormone-mediated JAK2 autophosphorylation. Synonyms: Benzene Hexabromide; JAK2 Inhibitor II. Grades: >98%. CAS No. 1837-91-8. Molecular formula: C6H6Br6. Mole weight: 557.54. | |
| 1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarbonyl Chloride | 1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarbonyl Chloride is used in the synthesis of 6-substituted-4- (3-bromophenylamino) quinazoline derivatives which functions as irreversible inhibitor of epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor (HER-2) tyrosine kinases. Group: Biochemicals. Grades: Highly Purified. CAS No. 59826-28-7. Pack Sizes: 25mg, 50mg. Molecular Formula: C7H10ClNO, Molecular Weight: 159.61. US Biological Life Sciences. | Worldwide |
| 1,2-bis(4-methylpiperazin-1-yl)ethanone | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: Piperazine, 1-methyl-4-[(4-methyl-1-piperazinyl)acetyl]-(5CI); Nintedanib Impurity E. Grades: ≥95%. CAS No. 856843-88-4. Molecular formula: C12H24N4O. Mole weight: 240.35. | |
| 1,3-dimethyl-1H-indazol-6-amine | 1,3-dimethyl-1H-indazol-6-amine is an impurity in the synthesis of Pazopanib, which is a potent and selective multi-targeted receptor tyrosine kinase inhibitor for the treatment of renal cell carcinoma and soft tissue sarcoma. Synonyms: 1H-Indazol-6-amine, 1,3-dimethyl-; 1,3-Dimethyl-6-amino-1H-indazole; Pazopanib Impurity 17; 1,3-Dimethyl-1H-indazol-6-ylamine; Pazopanib Impurity 3. Grades: 97.0%. CAS No. 221681-92-1. Molecular formula: C9H11N3. Mole weight: 161.20. | |
| 1-(4-((3-Chloro-4-fluorocyclohexyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one | One of the impurities of Dacomitinib. Dacomitinib, aslo known as PF-299 and PF-00299804 or PF299804, is an orally bioavailable, highly selective, second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor (EGFR) family of tyrosine kinases (ErbB family) with potential antineoplastic activity. Synonyms: 2-Pyrrolidinone, 1-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-5-hydroxy-; Dacomitinib Impurity WYQJ. Grades: ≥95%. CAS No. 2190490-31-2. Molecular formula: C19H16ClFN4O3. Mole weight: 402.81. | |
| 1-[4-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one | 1-[4-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one is an inhibitor for brutons tyrosine kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 936563-92-7. Pack Sizes: 10mg, 25mg. Molecular Formula: C25H24N6O2, Molecular Weight: 440.5. US Biological Life Sciences. | Worldwide |
| 1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-hydroxyphenyl)urea | An impurity of Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: Regorafenib Urea Impurity; Urea, N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-(2-fluoro-4-hydroxyphenyl)-. CAS No. 1333390-56-9. Molecular formula: C14H9ClF4N2O2. Mole weight: 348.68. | |
| 1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea | 1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea is an impurity of Sorafenib (S676850), a kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1129683-83-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C14H10ClF3N2O2, Molecular Weight: 330.69. US Biological Life Sciences. | Worldwide |
| 1- (4-Chloro-3- (trifluoromethyl) phenyl) urea | 1- (4-Chloro-3- (trifluoromethyl) phenyl) urea is an impurity of Sorafenib (S676850); a multiple kinase inhibitor targeting both RAF and receptor tyrosine kinases that promote angiogenesis. Also antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C8H6ClF3N2O, Molecular Weight: 238.59. US Biological Life Sciences. | Worldwide |
| 1-(4-Chloro-3-(trifluoromethyl)phenyl)urea | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: N-[4-Chloro-3-(trifluoromethyl)phenyl]urea; Sorafenib Impurity 1; Sorafenib related compound 1; 1-[3-(Trifluoromethyl)-4-chlorophenyl]urea; Sorafenib Related Compound 9. Grades: > 95%. CAS No. 343247-69-8. Molecular formula: C8H6ClF3N2O. Mole weight: 238.59. | |
| 1,4-Dihydro-7-methoxy-4-oxo-6-quinolinecarboxamide | 1,4-Dihydro-7-methoxy-4-oxo-6-quinolinecarboxamide is a metabolite of Lenvatinib (L329400) which is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 417724-81-3. Pack Sizes: 1mg, 5mg. Molecular Formula: C11H10N2O3, Molecular Weight: 218.21. US Biological Life Sciences. | Worldwide |
| 1-Boc-pyrazole-4-boronic Acid Pinacol Ester | 1-Boc-pyrazole-4-boronic Acid Pinacol Ester is used as a reagent in the synthesis of several inhibitors including thieno[3,2-c]pyridin-4-amines which are a novel series of Brutons tyrosine kinase (BTK) inhibitors which can be used in drug design. Group: Biochemicals. Grades: Highly Purified. CAS No. 552846-17-0. Pack Sizes: 1g, 2.5g. Molecular Formula: C14H23BN2O4, Molecular Weight: 294.149999999999. US Biological Life Sciences. | Worldwide |
| 1-Chloro-3-iodo-5- (trifluoromethyl) benzene | 1-Chloro-3-iodo-5- (trifluoromethyl) benzene has been used in the research of Bruton's tyrosine kinase inhibitors through the synthesis of pyrimidinyl bipiperidine.1. Group: Biochemicals. Grades: Highly Purified. CAS No. 1189352-83-7. Pack Sizes: 250mg, 1g. Molecular Formula: C7H3ClF3I, Molecular Weight: 306.45. US Biological Life Sciences. | Worldwide |
| 1H-?Pyrazole-?3-?carboxaldehyde | 1H-?Pyrazole-?3-?carboxaldehyde is an intermediate used to prepare fused pyrrole carboxylic acids as novel, potent D-?amino acid oxidase (DAO) inhibitors. It is also a building block to synthesize α-?substituted benzylidene malononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2?/neu tyrosine kinases. Group: Biochemicals. Grades: Highly Purified. CAS No. 3920-50-1. Pack Sizes: 1g, 5 g. Molecular Formula: C4H4N2O, Molecular Weight: 96.09. US Biological Life Sciences. | Worldwide |
| 1-Methyl-4-(4-nitrophenyl)piperazine | 1-methyl-4-(4-nitrophenyl)piperazine was a reagent in the preparation of diaminopyrimidines as reversible and irreversible inhibitors of mutant EGFR tyrosine kinases for treatment of non-small-cell lung cancer. It was also used in the prepn. of disubstituted pyrimidine compds. as EGFR or/and ALK inhibitors useful in the treatment of diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 16155-03-6. Pack Sizes: 500mg, 1g. Molecular Formula: C11H15N3O2, Molecular Weight: 221.26. US Biological Life Sciences. | Worldwide |
| 1-Naphthyl PP1 | Selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl. (IC50 values are 1.0, 0.6, 0.6, 18 and 22 uM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively). Preferentially inhibits mutant over wild-type kinases (IC50 values are 1.5 vs 1000 nM for I338G v-src and v-src respectively). Group: Biochemicals. Grades: Highly Purified. CAS No. 221243-82-9. Pack Sizes: 10mg, 50mg. Molecular Formula: C19H19N5. US Biological Life Sciences. | Worldwide |
| 1-Naphthyl PP1 hydrochloride | 1-Naphthyl PP1 hydrochloride is a selective inhibitor of src family kinases, including v-Src and c-Fyn, tyrosine kinase c-Abl and CAMK II with IC50 values of 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively. It was considerably more potent and showed distinct substituent effects at the pyrazolopyrimidine core. It was cell-active, and potently blocked prostate cancer cell proliferation by inducing G2/M arrest. Uses: 1-naphthyl pp1 hydrochloride could potently block prostate cancer cell proliferation by inducing g2/m arrest. Synonyms: 1-Tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine hydrochloride;1-NA-PP 1 hydrochloride. Grades: >98 %. CAS No. 956025-47-1. Molecular formula: C19H20ClN5. Mole weight: 353.85. | |
| 1-NA-PP1 | 1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. Synonyms: 1-(Tert-Butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1-Naphthyl PP1. CAS No. 221243-82-9. Molecular formula: C19H19N5. Mole weight: 317.39. | |
| 1-Phenylethanamine | 1-Phenylethanamine is a potential central nervous system stimulant and a related compound of β-phenylethylamine. Due to the replacement of its benzene ring with an indole group, its brain glycogenolytic activity is significantly reduced. Therefore, 1-Phenylethanamine can be used to study the impact of the chemical structure of phenylethylamine derivatives on central nervous system activity. In addition, 1-Phenylethanamine can also be used to synthesize the tyrosine kinase ( tyrosine kinase ) inhibitor CLM3 (HY-164413) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DL-α-Methylbenzylamine. CAS No. 618-36-0. Pack Sizes: 5 g. Product ID: HY-W012848. | |
| 2-((1-Acetyl-3-iodo-1H-indazol-6-yl)thio)-N-methylbenzamide | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: Benzamide, 2-[(1-acetyl-3-iodo-1H-indazol-6-yl)thio]-N-methyl-; Axitinib impurity YXA. Grades: ≥95%. CAS No. 1639138-00-3. Molecular formula: C17H14IN3O2S. Mole weight: 451.28. | |
| 2-(1-Piperidino)aniline | 2-(1-Piperidino)aniline is used to prepare oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B. It is also used to synthesize benzimidazole derivatives as AMP-activated protein kinase activators. Group: Biochemicals. Grades: Highly Purified. CAS No. 39643-31-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C11H16N2. US Biological Life Sciences. | Worldwide |
| 2-[[(1R,2S)-2-Aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-5-pyrimidinecarboxamide | 2-[[(1R,2S)-2-Aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-5-pyrimidinecarboxamide is a highly selective spleen tyrosine kinase (Syk) inhibitor that is used in the treatment of leukemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 1370261-96-3. Pack Sizes: 500ug, 1mg. Molecular Formula: C19H23N9O, Molecular Weight: 393.45. US Biological Life Sciences. | Worldwide |
| 2-[2-(Diethylamino)ethyl]-1H-isoindole-1,3(2H)-dione | 2-[2-(Diethylamino)ethyl]-1H-isoindole-1,3(2H)-dione is an intermediate in synthesizing Sunitinib-d4 (S820003), a labelled Sunitinib (S820000), a multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C14H14D4N2O2, Molecular Weight: 250.33. US Biological Life Sciences. | Worldwide |
| 2,2'-(piperazine-1,4-diyl)bis(N-methyl-N-(4-nitrophenyl)acetamide) | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: Nintedanib Impurity G. Grades: ≥95%. CAS No. 2410649-54-4. Molecular formula: C22H26N6O6. Mole weight: 470.48. | |
| (2, 3, 4-Trimethoxyphenyl) boronic Acid | (2, 3, 4-Trimethoxyphenyl) boronic Acid is a reagent used in the synthesis of heteroaryl, mono and bicyclic compounds which may be used as inhibitors for EGF and PDGF receptor tyrosine kinases. Also used in the synthesis of non-steroidal CYP 17 inhibitors in the treatment of prostate cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 118062-05-8. Pack Sizes: 1g, 5g. Molecular Formula: C9H13BO5. US Biological Life Sciences. | Worldwide |
| 2,3,4-Tri-O-acetyl-6-methyl- β-D-glucopyranuronosyl Genistein Glucuronide Methyl Ester Triacetate | 2,3,4-Tri-O-acetyl-6-methyl- β-D-glucopyranuronosyl Genistein Glucuronide Methyl Ester Triacetate is the protected metabolite of Genistein (G350000) which exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C41H42O23. US Biological Life Sciences. | Worldwide |
| 2,3-Dihydro-3-(1H-indol-3-ylmethylene)-2-oxo-1H-indole-5-sulfonamide | A potent small molecule inhibitor of spleen tyrosine kinase (Syk). Group: Biochemicals. Grades: Highly Purified. CAS No. 181223-16-5. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 2-((3-Iodo-1H-indazol-6-yl)thio)-N-methylbenzamide | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: Benzamide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-methyl-. Grades: > 95%. CAS No. 885126-34-1. Molecular formula: C15H12IN3OS. Mole weight: 409.25. | |
| 2-[[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]amino]-2-oxoacetic acid | An impurity of Neratinib, which is an irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Synonyms: Neratinib Impurity AJCS. Grades: ≥95%. CAS No. 1144516-13-1. Molecular formula: C26H20ClN5O5. Mole weight: 517.92. | |
| 2, 4, 6, 8-Tetrachloropyrimido[5, 4-d]pyrimidine | Potential tyrosine kinase signal transduction inhibitor. A pyrimido[5,4-d]pyrimidine derivative used as an intermediate in the preparation of nucleoside transporter 1 inhibitors and potential modulators of the activity of antimetabolite antitumor agents. Group: Biochemicals. Alternative Names: Tetrachloropyrimido[5, 4-d]pyrimidine; NSC 96654. Grades: Highly Purified. CAS No. 32980-71-5. Pack Sizes: 500mg, 1g. Molecular Formula: C?Cl?N?, Molecular Weight: 269.9. US Biological Life Sciences. | Worldwide |
| 2-(4-Amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-phenol | Used in the preparation of tyrosine and phosphoinositide kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1092787-78-4. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 2,4-Dichloro-3-aminophenol Hydrochloride | 2,4-Dichloro-3-aminophenol Hydrochloride is a useful reagent in the study fo aryl-pyrimidinyl ureas preparation as potential FGFR tyrosine kinase inhibitors and antitumor agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 61693-43-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C6H5Cl2NO; HCl, Molecular Weight: 178.023646. US Biological Life Sciences. | Worldwide |
| 2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: 4-Methyl-N-(4-nitrophenyl)-1-piperazineacetamide; Nintedanib Impurity F. Grades: ≥95%. CAS No. 708279-23-6. Molecular formula: C13H18N4O3. Mole weight: 278.31. | |
| 2-(5-Amino-1-tert-butyl-4-cyano)methoxyphenyl | Intermediate in the preparation of tyrosine and phosphoinositide kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester | 2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester is an intermediate in the synthesis of Erlotinib (E625000, HCl); a selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor and antineoplastic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 179688-27-8. Pack Sizes: 250mg, 500mg. Molecular Formula: C15H23NO6, Molecular Weight: 313.35. US Biological Life Sciences. | Worldwide |
| 2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Uses: 2-amino-4,5-bis(2-methoxyethoxy)benzonitrile is an impurity of erlotinib (e625008), a egfr-targeted drug in the treatment of non-small cell lung cancer. egfr small tyrosine kinase inhibitor that shows most substantial effect on tumor growth inhibition and animal survival. Synonyms: 2-amino-4,5-bis(2-methoxyethoxy)benzonitrile; 2-amino-4,5-bis(2-methoxyethoxy)benzonitrile. Grades: > 95 %. CAS No. 950596-58-4. Molecular formula: C13H18N2O4. Mole weight: 266.29. | |
| 2-Amino-5,6-dimethoxypyridine | 2-Amino-5,6-dimethoxypyridine is used in the design of Spleen Tyrosine Kinase (Syk) inhibitors used in the treatment of autoimmune diseases such as asthma, rheumatoid arthitis and SLE. Group: Biochemicals. Grades: Highly Purified. CAS No. 127980-46-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C7H10N2O2, Molecular Weight: 154.169999999999. US Biological Life Sciences. | Worldwide |
| 2-Aminomethyl-3-chloropyrazine | 2-Aminomethyl-3-chloropyrazine is used in the discovery of 8-Amino-imidazo[1,5-a]pyrazine-based Brutons tyrosine kinase (BTK) inhibitors for treating rheumatoid arthritis. Group: Biochemicals. Grades: Highly Purified. CAS No. 771581-15-8. Pack Sizes: 50mg, 250mg. Molecular Formula: C5H6ClN3, Molecular Weight: 143.57. US Biological Life Sciences. | Worldwide |
| 2-Amino-N-(2,3-dichloro-6-methylphenyl)thiazole-5-carboxamide | 2-Amino-N-(2,3-dichloro-6-methylphenyl)thiazole-5-carboxamide is an impurity of the anti-cancer drug Dasatinib (D193600). Dasatinib is a new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. Antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C11H9Cl2N3OS, Molecular Weight: 302.18. US Biological Life Sciences. | Worldwide |
| 2-Amino-N-(2,4-dichloro-6-methylphenyl)thiazole-5-carboxamide | 2-Amino-N-(2,4-dichloro-6-methylphenyl)thiazole-5-carboxamide is an impurity of the anti-cancer drug Dasatinib (D193600). Dasatinib is a new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. Antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C11H9Cl2N3OS, Molecular Weight: 302.18. US Biological Life Sciences. | Worldwide |
| 2-Amino-N-(3,6-dichloro-2-methylphenyl)thiazole-5-carboxamide | 2-Amino-N-(3,6-dichloro-2-methylphenyl)thiazole-5-carboxamide is an impurity of the anti-cancer drug Dasatinib (D193600). Dasatinib is a new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. Antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C11H9Cl2N3OS, Molecular Weight: 302.18. US Biological Life Sciences. | Worldwide |
| 2-Amino-N-(o-tolyl)-thiazole-5-carboxamide | 2-Amino-N-(o-tolyl)-thiazole-5-carboxamide is an impurity of the anti-cancer drug Dasatinib (D193600). Dasatinib is a new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. Antineoplastic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1184914-03-1. Pack Sizes: 50mg, 100mg. Molecular Formula: C11H11N3OS, Molecular Weight: 233.29. US Biological Life Sciences. | Worldwide |
| 2-chloro-N-methyl-N-(4-nitrophenyl)acetamide | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: Acetamide, 2-chloro-N-methyl-N-(4-nitrophenyl)-; α-Chloro-N-methyl-p-nitroacetanilide; Nintedanib Impurity B. Grades: ≥95%. CAS No. 2653-16-9. Molecular formula: C9H9ClN2O3. Mole weight: 228.63. | |
| 2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide | 2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide can be used as reactant/reagent for synthetic preparation of oxindole derivatives as inhibitors of tyrosine kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 2653-16-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H9ClN2O3. US Biological Life Sciences. | Worldwide |
| 2-Fluoro-3, 4-methylenedioxyphenyl Boronic acid | 2-Fluoro-3, 4-methylenedioxyphenyl Boronic acid is used in the synthetic preparation of potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk). Group: Biochemicals. Grades: Highly Purified. CAS No. 943830-75-9. Pack Sizes: 5mg, 10mg. Molecular Formula: C7H6BFO4, Molecular Weight: 183.93. US Biological Life Sciences. | Worldwide |
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