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| Product | Description | |
|---|---|---|
| UC 112 | UC 112. Group: Biochemicals. Grades: Purified. CAS No. 383392-66-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| UC 112 | UC-112 is an IAP inhibitor (IC50 values from 0.7 - 3.4 μM). UC-112 also potently inhibits the growth of P-glycoprotein. Uses: Iap inhibitor. Synonyms: UC-112; UC 112; UC112; 5-((benzyloxy)methyl)-7-(pyrrolidin-1-ylmethyl)quinolin-8-ol; (Z,6R)-2-methyl-6-[(5R,9R,10R,13R,14R,17R)-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,9,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]hept-2-enoic acid. Grades: ≥98%. CAS No. 383392-66-3. Molecular formula: C22H24N2O2. Mole weight: 348.44. |  |
| Antibiotic UCN-01 (7-Hydroxystaurosporine, UCN-01) | Isolated from Streptomyces sp., Antibiotic UCN-01 inhibits protein kinase C (PKC) and cyclin-dependent kinase 2 (CDK2) resulting in accumulation of cells in the G1 phase and induction of apoptosis. UCN-01 also enhances the cytotoxicity of other anti-cancer drugs, such as DNA-damaging agents and anti-metabolite drugs, through putative abrogation of G2 and/or S phase accumulation induced by these anti-cancer agents. Group: Biochemicals. Alternative Names: 7-Hydroxystaurosporine, UCN-01. Grades: Highly Purified. CAS No. 112953-11-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-Octadecyltrichlorosilane | N-Octadecyltrichlorosilane. Group: Silanes and Silicones. CAS No. 112-04-9. Product ID: O9750. Categories: octadecyltrichlorosilane, trichloro(octadecyl)silane, silane, trichlorooctadecyl-. |  |
| UCH9 | UCH9 is an antitumor antibiotic produced Streptomyces. II. It exhibits bacteriophage and gram-positive bacteria activity. Synonyms: UCH-9; UCH 9. Molecular formula: C55H82O24. Mole weight: 1127.2. | |
| UCN-01 | KRX-0601, also known as UCN-01, is a synthetic derivative of staurosporine with antineoplastic activity. It inhibits many phosphokinases, including the serine/threonine kinase AKT, calcium-dependent protein kinase C, and cyclin-dependent kinases. This agent arrests tumor cells in the G1/S of the cell cycle and prevents nucleotide excision repair by inhibiting the G2 checkpoint kinase chk1, resulting apoptosis. Uses: Antineoplastic agents. Synonyms: Antibiotic UCN 01; UCN01; Staurosporine; 7-hydroxystaurosporine; KW-2401; KW 2401; KW2401; (3R,9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one; (+)-UCN-01; KRX 0601; NSC 638850. Grades: >99% by HPLC. CAS No. 112953-11-4. Molecular formula: C28H26N4O4. Mole weight: 482.53. | |
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