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Usnic acid, a lichen-derived secondary metabolite, has a unique dibenzofuran skeleton. Usnic acid has excellent anticancer and antimicrobial properties. Usnic acid significantly inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1 [1]. Uses: Scientific research. Group: Natural products. CAS No. 125-46-2. Pack Sizes: 100 mg; 500 mg. Product ID: HY-N0656.
Usnic acid
Usnic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 125-46-2. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C18H16O7. US Biological Life Sciences.
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Usnic acid
Usnic acid is a naturally occurring dibenzofuran derivative found in several lichen species with the formula C18H16O7. It was first isolated by German scientist W. Knop in 1844 and first synthesized between 1933-1937 by Curd and Robertson. Usnic acid was identified in many genera of lichens including Usnea, Cladonia, Hypotrachyna, Lecanora, Ramalina, Evernia, Parmelia and Alectoria. Although it is generally believed that usnic acid is exclusively restricted to lichens, in a few unconfirmed isolated cases. The compound was found in kombucha tea and non-lichenized ascomycetes. At normal conditions, usnic acid is a bitter, yellow, solid substance.It is known to occur in nature in both the d-and l-forms as well as a racemic mixture. Salts of usnic acid are called usnates (e.g. copper usnate). Usnic acid can be used in cosmetics material. Uses: Bleeding, antibacterial, anti-inflammatory. Synonyms: 1,3(2H,9bH)-Dibenzofurandione, 2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-; 2,6-Diacetyl-7,9-dihydroxy-8,9b-dimethyl-1,3(2H,9bH)-dibenzofurandione; (±)-Usnic acid; 2,6-Diacetyl-7,9-dihydroxy-8,9b-dimethyldibenzo[b,d]furan-1,3(2H,9bH)-dione; NSC 8517; Usnein; Usniacin; Usno. Grades: >98%. CAS No. 125-46-2. Molecular formula: C18H16O7. Mole weight: 344.32.
Usnic Acid
Usnic acid, a lichen-derived secondary metabolite, has a unique dibenzofuran skeleton. Usnic acid has excellent anticancer and antimicrobial properties. Usnic acid significantly inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3(2H,9bH)-Dibenzofurandione, 2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-. Product Category: Inhibitors. Appearance: Solid. CAS No. 125-46-2. Molecular formula: C18H16O7. Mole weight: 344.32. Purity: 0.98. Canonical SMILES: O=C(C1(C)C(OC2=C(C(C)=O)C(O)=C(C)C(O)=C12)=C3)C(C(C)=O)C3=O. Density: 1.54 g/cm³. Product ID: ACM125462. Alfa Chemistry ISO 9001:2015 Certified.
Usnic Acid
Usnic Acid - Product ID: NST-10-49. Category: Polyketides. Purity: 98%. Test method: HPLC. CAS No. 7562-61-0. Pack Sizes: 25g, 50g, 125g, 250g. Appearance: Brown fine powder. Molecular formula: C18H16O7. Mole weight: 344.32. Storage: +2 +8 °C.
(+)-Usnic acid
(+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR , and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay , with anti-cancer and anti-inflammatory activity. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus , Enterococcus faecalis , and Enterococcus faecium [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 7562-61-0. Pack Sizes: 1 g; 5 g. Product ID: HY-N0656A.
(-)-Mycousnine
(-)-Mycousnine is a microbial metabolite of usnic acid produced by the strain of M. nawae that has antibacterial and antifungal activities. It is active against the Gram-positive bacteria B. subtilis, K. rhizophila, and S. aureus (MICs = 4, 8, and 4 g/ml, respectively). (-)-Mycousnine is also active against the fungi T. mentagrophytes, T. rubrum, and C. albicans (MICs = 25, 25, and 100 μg/ml, respectively). Synonyms: Mycousnine. Grades: >95% by HPLC. CAS No. 77480-55-8. Molecular formula: C19H20O8. Mole weight: 376.36.
(S)-usnate reductase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is reduced-(S)-usnate:NAD+ oxidoreductase (ether-bond-forming). This enzyme is also called L-usnic acid dehydrogenase. Group: Enzymes. Synonyms: L-usnic acid dehydrogenase. Enzyme Commission Number: EC 1.1.1.199. CAS No. 77237-99-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0102; (S)-usnate reductase; EC 1.1.1.199; 77237-99-1; L-usnic acid dehydrogenase. Cat No: EXWM-0102.
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