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Valaciclovir Valaciclovir. Uses: For analytical and research use. Group: Impurity standards. CAS No. 124832-26-4. Molecular formula: C13H20N6O4. Mole weight: 324.34. Catalog: APB124832264. Alfa Chemistry Analytical Products 4
Valaciclovir EP Impurity E Valaciclovir EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 124832-31-1. Molecular formula: C21H26N6O6. Mole weight: 458.48. Catalog: APB124832311. Alfa Chemistry Analytical Products 4
Valaciclovir HCl L-Valine-2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester. veterinary use. CAS No. 124832-27-5. Product ID: 8-01812. Molecular formula: C9H6FN. Mole weight: 147.16. CarboMer Inc
Valacyclovir Hydrochloride Hydrate (L-Valine 2-(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-ylmethoxy)ethyl Ester Hydrochloride hydrate; Valaciclovir) Valacyclovir is a prodrug of Acyclovir with inhibitory activity against herpes simplex virus types 1 (HSV-1), 2 (HSV-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), and cytomegalovirus (CMV). Valacyclovir is phosphorylated by viral thymidine kinase to acyclovir triphosphate (the active metabolite) which then inhibits herpes viral DNA replication by competitive inhibition of viral DNA polymerase, and by incorporation into and termination of the growing viral DNA chain. Group: Biochemicals. Grades: Highly Purified. CAS No. 124832-27-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 4
Worldwide
1-(3,5-Di-O-acetyl-β-D-deoxyribofuranosyl)-4-(1,2,4-triazol-1-yl)-5-methylpyrmidin-2-one 1-(3,5-Di-O-acetyl-β-D-deoxyribofuranosyl)-4-(1,2,4-triazol-1-yl)-5-methylpyrmidin-2-one, also known as Valaciclovir intermediate, is crucial in the synthesis of Valaciclovir, a potent antiviral medication. It's primarily utilized to the research of treating herpes simplex and shingles. Synonyms: 1-(3,5-Di-O-acetyl-2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-4-(1,2,4-triazol-1-yl)-2(1H)-pyrimidinone; 5-Methyl-3'-O,5'-O-diacetyl-4-(1H-1,2,4-triazole-1-yl)-4-desamino-2'-deoxycytidine; [(2R,3S,5R)-3-acetoxy-5-[5-methyl-2-oxo-4-(1,2,4-triazol-1-yl)pyrimidin-1-yl]tetrahydrofuran-2-yl]methyl acetate; 1-(3,5-Di-O-acetyl-2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-4-(1,2,4-triazol-1-yl)-2(1H)-pyrimidinone; 1-(3,5-Di-O-acetyl-2-deoxypentofuranosyl)-5-methyl-4-(1H-1,2,4-triazol-1-yl)pyrimidin-2(1H)-one. CAS No. 80991-41-9. Molecular formula: C16H19N5O6. Mole weight: 377.36. BOC Sciences 2
Acyclovir United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitespharma & vet compounds & metabolites. Alternative Names: Valaciclovir Imp. B (EP), Gerpevir, Vicclox, Zirax, 111U90, Aciclovir, 2-Amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one, 535U76, BioVir II, Valaciclovir Hydrochloride Anhydrous Imp. B (EP), 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one, Acyclovir, Vipral,Valaciclovir Hydrochloride Imp. B (EP), GW277085A, Avirase, 23W91, ACV, Rouz-Aciclovir, Aciclovir, Aciclovir Test Mix 1, Aciclovir, NSC 645011, 559U81, BW 248U, Novirus, Lovir, Virax, Virless, Virorax, Acivir, CCI 22890, Ph Eur Valaciclovir Impurity B, Virovir, 9-(2-Hydroxyethoxymethyl)guanine, Axiluowei, Zovirax, Poviral, Acyclo V, BioVir I, Cargosil, Acycloguanosine, Aciclovir, Wellcome 248U, Acicloftal, Zyclir, USP Valacyclovir Related Compound B, Herpevir, 4793W93. Alfa Chemistry Analytical Products
Bis Valacyclovir An impurity of Valacyclovir. Synonyms: Valacyclovir Impurity P (EP), Bis-valaciclovir in USP monograph (impurity K). Grades: > 95%. CAS No. 1356019-51-6. Molecular formula: C14H18N10O4. Mole weight: 390.36. BOC Sciences 8
Bis Valacyclovir This impurity is listed in Ph. Eur. monograph for Valaciclovir HCl as impurity P and Bis-valaciclovir in USP monograph (impurity K). Group: Biochemicals. Grades: Highly Purified. CAS No. 1356019-51-6. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
BOC-L-Valine Boc-L-Valine is a valine derivative. CAS No. 13734-41-3. Product ID: PAP-0014. Molecular formula: C10H19NO4. Category: Amino acid. Product Keywords: Amino Acid Series; BOC-L-Valine; PAP-0014; Amino acid; C10H19NO4; 13734-41-3. Color: White. EC Number: 237-307-6. Physical State: Fine Crystalline Powder. Solubility: Chloroform, DMF, DMSO, Methanol. Storage: Keep in dark place,Sealed in dry,Room Temperature. Applications: Boc-l-valine is used in peptide synthesis as amino acid protective monomer. Side chain synthesis of lovir series such as valaciclovir or valaciclovir, peptide synthesis. Boiling Point: 357.82°C (rough estimate). Melting Point: 77-80 °C(lit.). Density: 1.1518 (rough estimate). Product Description: Boc-l-valine is used in peptide synthesis as amino acid protective monomer. Side chain synthesis of lovir series such as valaciclovir or valaciclovir, peptide synthesis. CD Formulation
Dimethyl-pyridin-4-yl-amine (DMAP) Dimethyl-pyridin-4-yl-amine is a highly efficient catalyst for acylation reactions. Uses: A highly efficient catalyst for acylation reactions. Synonyms: 4-(dimethylamino)-pyridin; 4-Dimethylaminepyridine; gamma-(Dimethylamino)pyridine; N,N-Dimethyl-4-aminopyridine; n,n-dimethyl-4-pyridinamin; p-Dimethylaminopyridine; Pyridine, 4-(dimethylamino)-; AURORA KA-6495; DMAP; 4-dimethylaminopyridine; 4-DMAP; γ-(Dimethylamino)pyridine; USP Valacyclovir Related Compound G; Valaciclovir EP Impurity G; Valacyclovir USP Related Compound G. Grades: 98%. CAS No. 1122-58-3. Molecular formula: C7H10N2. Mole weight: 122.17. BOC Sciences 4
Guanine United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsbritish pharmacopoeiapharmacopoeial standards. Alternative Names: Ganciclovir Imp. F (EP), 2-Amino-1,7-dihydro-6H-purin-6-one, Ph Eur Aciclovir Impurity B, 559U81, AH 13779, Valaciclovir Imp. A (EP), Guanine, Ph Eur Valaciclovir Impurity A,Aciclovir Imp. B (EP), 2-Amino-1,9-dihydro-6H-purin-6-one, Guanine, Valaciclovir Hydrochloride Anhydrous Imp. A (EP), Valaciclovir Hydrochloride Imp. A (EP). Alfa Chemistry Analytical Products
L-Valacyclovir Hydrochloride Valaciclovir HCl is an antiviral drug used in the management of herpes simplex, herpes zoster, and herpes B. Synonyms: Valacyclovir hydrochloride; Valacyclovir HCl. Grades: >98%. CAS No. 124832-27-5. Molecular formula: C13H20N6O4.HCl. Mole weight: 360.8. BOC Sciences 9
L-Valine Methyl Ester Hydrochloride L-Valine Methyl Ester Hydrochloride is used in the synthesis of Valaciclovir (V085000), the L-Valine ester prodrug of Acyclovir (A192400), orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Antiviral. Group: Biochemicals. Alternative Names: (S)-Valine Methyl Ester Hydrochloride; Methyl (S)-2-Amino-3-methylbutanoate Hydrochloride; Methyl (S)-Valinate Hydrochloride; Methyl L-Valinate Hydrochloride; Methyl Valinate Hydrochloride; NSC 197198; NSC 22920; Valine Methyl Ester Hydrochloride. Grades: Highly Purified. CAS No. 6306-52-1. Pack Sizes: 25g. US Biological Life Sciences. USBiological 3
Worldwide
N-Benzyloxycarbonyl-L-Valine Cbz-L-Valine. Valaciclovir intermediate. CAS No. 1149-26-4. Product ID: 1-01626. Molecular formula: C13H17NO4. Mole weight: 251.28. Purity: 0.98. Properties: mp 55-60°C. CarboMer Inc
Sodium glucuronate Sodium glucuronate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: glucuronicacid,monosodiumsalt;4-FLUOROCINNAMONITRILE;3-(4-FLUOROPHENYL)-2-PROPENENITRILE;Sodium Glucurononate;VALACICLOVIR HYDROCHLORIDE HPLC;URSODEOXYCHOLICACID;Monosodium glucuronate. Product Category: Heterocyclic Organic Compound. CAS No. 7182-77-6. Molecular formula: C6H9O7?Na. Mole weight: 216.12. Purity: 0.96. IUPACName: sodium (2S,3S,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexanoate. Product ID: ACM7182776. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
Valacyclovir Valaciclovir is an antiviral drug used in the management of herpes simplex, herpes zoster, and herpes B. Uses: Antiviral agents. Synonyms: Valaciclovir; Valtrex. Grades: >98%. CAS No. 124832-26-4. Molecular formula: C13H20N6O4. Mole weight: 324.34. BOC Sciences 10
Valacyclovir hydrochloride Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. Valacyclovir hydrochloride inhibits HSV-1 W ( 50 =2.9 μg/ml). Valacyclovir hydrochloride is a proagent of Aciclovir (HY-17422) [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Valaciclovir hydrochloride. CAS No. 124832-27-5. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-17425A. MedChemExpress MCE
Valacyclovir hydrochloride Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. Valacyclovir hydrochloride inhibits HSV-1 W (50=2.9 μg/ml). Valacyclovir hydrochloride is a proagent of Aciclovir (HY-17422). Uses: Designed for use in research and industrial production. Additional or Alternative Names: VALACICLOVIR HCL;VALACICLOVIR HYDROCHLORIDE;VALACV;VALACYCLOVIR;VALACYCLOVIR HYDROCHLORIDE;L-VALINE 2-[(2-AMINO-1,6-DIHYDRO-6-OXO-9H-PURIN-9YL)METHOXY]ETHYL ESTER, HYDROCHLORIDE SALT;VALACICLOVIR HCL 99%;VALACICLOVIR HYDROCHLORIDE,98.0+%. Product Category: Inhibitors. CAS No. 124832-27-5. Molecular formula: C13H21ClN6O4. Mole weight: 360.8. Purity: 0.9972. Product ID: ACM124832275. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Valacyclovir Impurity K An impurity of Valaciclovir. Valacyclovir is the prodrug of acyclovir used to treat infectious diseases. Molecular formula: C14H18N10O4. Mole weight: 390.36. BOC Sciences 6
Valacyclovir Impurity N An impurity of Valaciclovir. Valacyclovir is the prodrug of acyclovir used to treat infectious diseases. Synonyms: Guaninyl Valacyclovir; N2-(Guanine-N2-yl)methyl]-9-[(2-hydroxyethoxy)methyl]guanine-L-valinate. Molecular formula: C19H25N11O5. Mole weight: 487.48. BOC Sciences 6
Valacyclovir Impurity O An impurity of Valaciclovir. Valacyclovir is the prodrug of acyclovir used to treat infectious diseases. Molecular formula: C22H33N11O7. Mole weight: 563.58. BOC Sciences 6
Valacyclovir Impurity Q An impurity of Valaciclovir. Valacyclovir is the prodrug of acyclovir used to treat infectious diseases. Molecular formula: C19H25N11O5. Mole weight: 487.48. BOC Sciences 6
Valacyclovir Related Compound D An impurity of Valacyclovir, an antiviral drug used for the treatment of herpes virus infections. Synonyms: Valaciclovir USP RC D; N-Ethyl Valacyclovir ; 2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl-N-ethyl-L-valinate. Grades: > 95%. CAS No. 1346747-69-0. Molecular formula: C15H15N5O4. Mole weight: 352.39. BOC Sciences 8
Valacyclovir Related Compound E An impurity of Valaciclovir. Valacyclovir is the prodrug of acyclovir used to treat infectious diseases. Synonyms: N-Carboxybenzyl D-Valacyclovir; N(Val)-Carboxybenzyl Valacyclovir; N-[(Phenylmethoxy)carbonyl]-D-valine 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]Ethyl Ester. CAS No. 124832-32-2. Molecular formula: C21H26N6O6. Mole weight: 458.48. BOC Sciences 6
Valganciclovir In cell culture model systems using Caco-2 cells for PEPT1 and SKPT cells for PEPT2, valganciclovir inhibited glycylsarcosine transport mediated by PEPT1 and PEPT2 with K(I) values (inhibition constant) of 1.68+/-0.30 and 0.043+/- 0.005 mM, respectively. The inhibition by valganciclovir was competitive in both cases. 37 patients were enrolled; 19 patients received treatment with VGV and 18 patients received treatment with GCV. The VGV was not inferior in efficacy to GCV as pre-emptive therapy, with rates of viral clearance at 28 days of 89.5% and 83%, respectively (P-value for non-inferiority = 0.030). Toxicities were similar between the 2 arms. No patients developed CMV disease. Patients being treated with an alemtuzumab-containing regimen received prophylaxis with either valaciclovir 500 mg orally daily orvalganciclovir 450 mg orally twice daily. None of the 20 patients randomized to valganciclovir experienced CMV reactivation (P =.004). Synonyms: Valganciclovir. Grades: >98%. CAS No. 175865-60-8. Molecular formula: C14H22N6O5. Mole weight: 354.36. BOC Sciences 8
Valganciclovir hydrochloride Valganciclovir (hydrochloride), the L-valyl ester of ganciclovir, is actually a prodrug for ganciclovir. Valganciclovir is an antiviral medication used to treat cytomegalovirus infections.IC50 Value:Target: CMVin vitro: In cell culture model systems using Caco-2 cells for PEPT1 and SKPT cells for PEPT2, valganciclovir inhibited glycylsarcosine transport mediated by PEPT1 and PEPT2 with K(I) values (inhibition constant) of 1.68+/-0.30 and 0.043+/- 0.005 mM, respectively. The inhibition by valganciclovir was competitive in both cases.in vivo: 37 patients were enrolled; 19 patients received treatment with VGV and 18 patients received treatment with GCV. The VGV was not inferior in efficacy to GCV as pre-emptive therapy, with rates of viral clearance at 28 days of 89.5% and 83%, respectively (P-value for non-inferiority = 0.030). Toxicities were similar between the 2 arms. No patients developed CMV disease. Patients being treated with an alemtuzumab-containing regimen received prophylaxis with either valaciclovir 500 mg orally daily orvalganciclovir 450 mg orally twice daily. None of the 20 patients randomized to valganciclovir experienced CMV reactivation (P =.004). Uses: Designed for use in research and industrial production. Additional or Alternative Names: VALGANCICLOVIR HYDROCHLORIDE;L-VALINE, 2-[(2-AMINO-1,6-DIHYDRO-6-OXO-9H-PURIN-9-YL)METHOXY]-3-HYDROXYPROPYL ESTER, MONOHYDROCHLORIDE;VALGANCICLOVIR HCL;L-V… Alfa Chemistry.

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