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| Product | Description | |
|---|---|---|
| Valdecoxib | Valdecoxib. Group: Biochemicals. Alternative Names: 4- (5-Methyl-3-phenyl-4-isoxazolyl) benzenesulfonamide; Bextra; SC 65872. Grades: Highly Purified. CAS No. 181695-72-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H14N2O3S. US Biological Life Sciences. |  Worldwide |
| Valdecoxib | Valdecoxib is a highly potent and selective inhibitor of COX-2 , with IC 50 s of 5 nM and 140 μM for COX-2 and COX-1, respeceively. Valdecoxib can be used in the research of arthritis and pain. Uses: Scientific research. Group: Natural products. Alternative Names: SC 65872. CAS No. 181695-72-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15762. |  |
| Valdecoxib-13c2,15N | Heterocyclic Organic Compound. Alternative Names: 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide-13C2,15N; Bextra-13C2,15N; SC 65872-13C2,15N; Valecoxib-13C2,15N; Valus-13C2,15N; Valz. CAS No. 1189428-23-6. Molecular formula: C1413CH14N15NO3S. Mole weight: 317.34. Appearance: White Solid. Catalog: ACM1189428236. |  |
| Valdecoxib 3'-Sulfonamide Impurity | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: ACN-027517; 3-(5-methyl-4-phenylisoxazol-3-yl)benzenesulfonamide. CAS No. 1373038-56-2. Molecular formula: C16H14N2O3S. Mole weight: 314.37. |  |
| Valdecoxib 3'-Sulfonyl Chloride Impurity | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: ACN-027516; 3-(5-methyl-4-phenylisoxazol-3-yl)benzene-1-sulfonyl chloride. CAS No. 1373038-57-3. Molecular formula: C16H12ClNO3S. Mole weight: 333.8. | |
| Valdecoxib (Bextra, 4- (5-Methyl-3-phenyl-4-isoxazolyl) benzenefulfonamide) | A nonsteroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic and antipyretic properties in animal models. An inhibitor of prostaglandin synthesis primarily through inhibition of COX-2. Group: Biochemicals. Alternative Names: Bextra, 4- (5-Methyl-3-phenyl-4-isoxazolyl) benzenefulfonamide. Grades: Highly Purified. CAS No. 181695-72-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Valdecoxib-D3 | Valdecoxib-D3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1219794-90-7. Molecular Formula: C16H11D3N2O3S. Mole Weight: 317.38. Catalog: APB1219794907. |  |
| Valdecoxib Disulfonamide Impurity | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: Parecoxib Impurity 1. Molecular formula: C22H23N3O7S2. Mole weight: 505.57. | |
| Valdecoxib Impurity 2 | Valdecoxib Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1062611-65-7. Molecular Formula: C25H33N3O4S. Mole Weight: 471.62. Catalog: APB1062611657. | |
| Valdecoxib Impurity 3 | Valdecoxib Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1391052-01-9. Molecular Formula: C17H16N2O3S. Mole Weight: 328.39. Catalog: APB1391052019. | |
| Valdecoxib Impurity A | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: 3-Phenyl-4-(4-aminosulfonylbenzyl)-5-methylisoxazole; 3-Phenyl-4-(4-aminosulfonylbenzyl)-5-methylisoxazole. CAS No. 1391052-01-9. Molecular formula: C17H16N2O3S. Mole weight: 328.39. | |
| Valdecoxib Impurity B | Valdecoxib Impurity B is a dimeric impurity of Valdecoxib. Synonyms: Valdecoxib Dimer; N-[4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonyl]-4-(5-methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide. CAS No. 1373038-60-8. Molecular formula: C32H25N3O6S2. Mole weight: 611.7. | |
| Valdecoxib Impurity C | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: 3-Phenyl-4-benzyl-5-methylisoxazole; 5-Methyl-3-phenyl-4-(phenylmethyl)isoxazole. CAS No. 139395-94-1. Molecular formula: C17H15NO. Mole weight: 249.32. | |
| Valdecoxib Impurity D | Valdecoxib Impurity D is a metabolite of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: Parecoxib Impurity 8; Valdecoxib Sulfonic Acid; 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonic Acid. CAS No. 181696-35-5. Molecular formula: C16H13NO4S. Mole weight: 315.35. | |
| Valdecoxib impurity (desulfonamide) | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: 5-Methyl-3,4-diphenylisoxazole; 5-methyl-3,4-diphenyl-1,2-oxazole; 5-Methyl-3,4-diphenyl-isoxazole; CHEMBL365033; AK110518. CAS No. 37928-17-9. Molecular formula: C16H13NO. Mole weight: 235.29. | |
| Valdecoxib Impurity E | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: Valdecoxib IMpurity-E; 3-(4-(4-(Chlorosulfonyl)phenyl)-5-methylisoxazol-3-yl)benzenesulfonyl chloride; 3-[4-(4-chlorosulfonylphenyl)-5-methyl-1,2-oxazol-3-yl]benzenesulfonyl chloride; 3-(4-(4-(Chlorosulfonyl)phenyl)-5-methylisoxazol-3-yl)benzene-1-sulfonyl chloride; YEC03863; 3-[4-[4-(Chlorosulfonyl)phenyl]-5-methyl-3-isoxazolyl]benzenesulfonyl chloride; 1-?Tert-?butyl 4-?ethyl 1H-?pyrazole-?1,?4-?dicarboxylate. CAS No. 1373038-63-1. Molecular formula: C16H11Cl2NO5S2. Mole weight: 432.3. | |
| Valdecoxib Impurity F | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: Valdecoxib Sulfonyl Chloride; 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonyl Chloride. CAS No. 509074-26-4. Molecular formula: C16H12ClNO3S. Mole weight: 333.8. | |
| Valdecoxib Impurity H | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: 3-Phenyl-4-(4-chlorosulfonylbenzyl)-5-methylisoxazole. CAS No. 1391051-82-3. Molecular formula: C17H14ClNO3S. Mole weight: 347.82. | |
| Valdecoxib Impurity I | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: 3-(5-methyl-4-(4-sulfamoylphenyl)isoxazol-3-yl)benzenesulfonamide; AKOS030530317; ZINC200584589; BC600176; 3-(3-Aminosulfonylphenyl)-4-(4-aminosulfonylphenyl)-5-methylisoxazole. CAS No. 1373038-59-5. Molecular formula: C16H15N3O5S2. Mole weight: 393.44. | |
| Valdecoxib Impurity J | The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells and rat brain tissue. Adult male Sprague-Dawley rats were administered parecoxib (10 or 30 mg kg(-1), IP) or isotonic saline twice a day starting 24 h after middle cerebral artery occlusion (MCAO) for three consecutive days. The selective COX-2 inhibitor parecoxib was delivered 20 min before or 20 min after the incision by intraperitoneal injection. Pretreatment with parecoxib markedly attenuated the pain hypersensitivity induced by incision. Uses: Cyclooxygenase 2 inhibitors. Synonyms: SC 69124; SC69124; SC-69124; Valus-P; Vorth-P. Grades: >98%. CAS No. 198470-84-7. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
| Valdecoxib Impurity N | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: 3-(5-Methyl-3-phenylisoxazol-4-yl)benzene-1-sulfonyl chloride; 3-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonyl chloride; 3-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonyl Chloride. CAS No. 1709956-95-5. Molecular formula: C16H12ClNO3S. Mole weight: 333.8. | |
| Valdecoxib impurity (Ring-open N-OH) | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: Deoxybenzoin Oxime; (1E)-1,2-Diphenylethanone Oxime; (E)-2-Phenylacetophenone Oxime. CAS No. 26306-06-9. Molecular formula: C14H13NO. Mole weight: 211.27. | |
| Valdecoxib m-Sulfonamide Impurity | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: Parecoxib Impurity 2. Molecular formula: C19H18N2O4S. Mole weight: 370.43. | |
| Valdecoxib N-Oxide | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Molecular formula: C16H14N2O4S. Mole weight: 330.36. | |
| Valdecoxib-phenyl-d5 | Labelled Valdecoxib, a nonsteroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic and antipyretic properties in animal models. An inhibitor of prostaglandin synthesis primarily through inhibition of COX-2. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 2-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Benzenesulfonamide, 2-(5-methyl-3-phenyl-4-isoxazolyl)-; Parecoxib Impurity 48. CAS No. 2304623-35-4. Molecular formula: C16H14N2O3S. Mole weight: 314.36. | |
| 2-(5-methyl-4-phenylisoxazol-3-yl)benzenesulfonamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 37. CAS No. 2304623-37-6. Molecular formula: C16H14N2O3S. Mole weight: 314.36. | |
| 3-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 09. CAS No. 386273-25-2. Molecular formula: C16H14N2O3S. Mole weight: 314.36. | |
| 3-methyl-4,5-diphenylisoxazole | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 38. CAS No. 75115-00-3. Molecular formula: C16H13NO. Mole weight: 235.28. | |
| 4-(3-methyl-4-phenylisoxazol-5-yl)benzenesulfonamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 39; Benzenesulfonamide, 4-(3-methyl-5-phenyl-4-isoxazolyl)-. Grades: 98%. CAS No. 181695-84-1. Molecular formula: C16H14N2O3S. Mole weight: 314.36. | |
| 4,4'-(5-methylisoxazole-3,4-diyl)dibenzenesulfonamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 15; Valdecoxib Impurity 13. CAS No. 2251048-58-3. Molecular formula: C16H15N3O5S2. Mole weight: 393.43. | |
| 4-(4-chlorophenyl)-5-methyl-3-phenylisoxazole | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 40. CAS No. 1448355-87-0. Molecular formula: C16H12ClNO. Mole weight: 269.72. | |
| 4,4'-(sulfonylbis(4,1-phenylene))bis(5-methyl-3-phenylisoxazole) | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 29. CAS No. 2338845-31-9. Molecular formula: C32H24N2O4S. Mole weight: 532.61. | |
| 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol | Intermediate for the preparation of Valdecoxib. Group: Biochemicals. Alternative Names: 5-Hydroxy-5-methyl-3,4-diphenylisoxazoline. Grades: Highly Purified. CAS No. 181696-73-1. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol-13C2, 15N | Intermediate for the preparation of Isotope Labeled Valdecoxib. Group: Biochemicals. Alternative Names: 5-Hydroxy-5-methyl-3,4-diphenylisoxazoline-13C2, 15N. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 4-(5-methyl-2-phenyloxazol-4-yl)benzenesulfonamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 47. Grades: >95%. CAS No. 2242749-01-3. Molecular formula: C16H14N2O3S. Mole weight: 314.36. | |
| 5-Methyl-3,4-diphenyl-4,5-dihydroisoxazol-5-ol | An intermediate for the preparation of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Uses: Intermediate for the preparation of valdecoxib. Synonyms: 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol. CAS No. 181696-73-1. Molecular formula: C16H15NO2. Mole weight: 253.30. | |
| ethyl 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonate | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Benzenesulfonic acid, 4-(5-methyl-3-phenyl-4-isoxazolyl)-, ethyl ester; Parecoxib Impurity 27. Grades: >95%. CAS No. 1884279-18-8. Molecular formula: C18H17NO4S. Mole weight: 343.40. | |
| N-((2-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)propionamide | N-((2-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)propionamide is an impurity of Parecoxib, which is a selective COX2 inhibitor and a water-soluble and injectable prodrug of valdecoxib. Uses: Cyclooxygenase 2 inhibitors. Synonyms: Propanamide, N-[[2-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
| N-((2-(5-methyl-4-phenylisoxazol-3-yl)phenyl)sulfonyl)propionamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 34. CAS No. 2304623-38-7. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
| N-[[3- (5-Methyl-3-phenyl-4-isoxazolyl) phenyl]sulfonyl]propanamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Sodium Impurity 14; Propanamide, N-[[3-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-. Grades: ≥95%. CAS No. 1709956-89-7. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
| N-((3-(5-methyl-4-phenylisoxazol-3-yl)phenyl)sulfonyl)propionamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 20. CAS No. 2229657-81-0. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
| N-((4-(3-methyl-5-phenylisoxazol-4-yl)phenyl)sulfonyl)propionamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Propanamide, N-[[4-(3-methyl-5-phenyl-4-isoxazolyl)phenyl]sulfonyl]-; Parecoxib Impurity 42. Grades: 98%. CAS No. 477594-28-8. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
| N-[[4- (5-Methyl-3-phenyl-4-isoxazolyl) phenyl]sulfonyl]butanamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Butanamide, N-[[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-; Parecoxib Impurity H. Grades: ≥95%. CAS No. 198470-91-6. Molecular formula: C20H20N2O4S. Mole weight: 384.45. | |
| N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)acetamide | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: N-[[4-(5-methyl-3-phenylisoxazol-4-yl)phenyl]sulfonyl]acetamide. CAS No. 198471-06-6. Molecular formula: C18H16N2O4S. Mole weight: 356.4. | |
| N-((4-(5-methyl-4-phenylisoxazol-3-yl)phenyl)sulfonyl)propionamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Propanamide, N-[[4-(5-methyl-4-phenyl-3-isoxazolyl)phenyl]sulfonyl]-; Parecoxib Impurity 21. CAS No. 2235371-89-6. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
| N-ethyl-4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Benzenesulfonamide, N-ethyl-4-(5-methyl-3-phenyl-4-isoxazolyl)-; Parecoxib Impurity 28. CAS No. 473465-11-1. Molecular formula: C18H18N2O3S. Mole weight: 342.41. | |
| N,N'-((5-methylisoxazole-3,4-diyl)bis(4,1-phenylenesulfonyl))dipropionamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 25. CAS No. 2251048-76-5. Molecular formula: C22H23N3O7S2. Mole weight: 505.56. | |
| Parecoxib | Parecoxib (SC 69124) is a highly selective and orally active COX-2 inhibitor, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. Parecoxib can be used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis in vivo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC 69124. CAS No. 198470-84-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-17474. | |
| Parecoxib Impurity 1 | An impurity of Parecoxib. The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells and rat brain tissue. Adult male Sprague-Dawley rats were administered parecoxib (10 or 30 mg kg(-1), IP) or isotonic saline twice a day starting 24 h after middle cerebral artery occlusion (MCAO) for three consecutive days. The selective COX-2 inhibitor parecoxib was delivered 20 min before or 20 min after the incision by intraperitoneal injection. Pretreatment with parecoxib markedly attenuated the pain hypersensitivity induced by incision. Synonyms: Valdecoxib Disulfonamide Impurity; Parecoxib Impurity H. Grades: 95%. CAS No. 1708094-99-8. Molecular formula: C22H23N3O7S2. Mole weight: 505.56. | |
| Parecoxib Impurity 10 | An impurity of Parecoxib which is a water-soluble and injectable prodrug of valdecoxib and a COX2 selective inhibitor. Grades: > 95%. Molecular formula: C16H12ClNO3S. Mole weight: 333.8. | |
| Parecoxib Impurity 11 | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: 4-(5-Methyl-4-phenylisoxazol-3-yl)benzenesulfonamide; 4-[5-Methyl-4-phenylisoxazol-3-yl]benzenesulfonamide; SCHEMBL6168344; BJYUOXUCQMUZRX-UHFFFAOYSA-N. Grades: > 95%. CAS No. 181696-12-8. Molecular formula: C16H14N2O3S. Mole weight: 314.37. | |
| Parecoxib Impurity 6 Sodium Salt | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Grades: > 95%. CAS No. 198470-92-7. Molecular formula: C20H19N2O4S.Na. Mole weight: 406.44. | |
| Parecoxib Impurity 7 | An impurity of Parecoxib which is an injectable pro drug of valdecoxib and a COX2 selective inhibitor. Synonyms: Benzenesulfonamide, N-hydroxy-4-(5-methyl-3-phenyl-4-isoxazolyl)-; UNII-6M6L09OU0A; Valdecoxib metabolite M2; N-hydroxy-4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonamide; 6M6L09OU0A; n-hydroxy-4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide; CHEMBL254418; SCHEMBL5481289; CHEMBL1182611; DTXSID30458535; BDBM50229774; PD119532; Q27265142; N-hydroxy-4-(5-methyl-3-phenyl-4-isoxazolyl)-benzenesulfonamide; N-hydroxy-4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide hydrate; N-Hydroxy-4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide monohydrate. Grades: > 95%. CAS No. 501093-49-8. Molecular formula: C16H14N2O4S. Mole weight: 330.36. | |
| Parecoxib Impurity D | An impurity of Parecoxib which is a water-soluble and injectable prodrug of valdecoxib and a COX2 selective inhibitor. Grades: > 95%. Molecular formula: C16H14N2O3S. Mole weight: 314.37. | |
| Parecoxib Impurity E | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Grades: > 95%. Molecular formula: C19H17N2O4S.Na. Mole weight: 392.41. | |
| Parecoxib Impurity HSJZ | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Grades: ≥95%. Molecular formula: C17H15NO4S. Mole weight: 329.37. | |
| Parecoxib Impurity HSYBZ | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Grades: ≥95%. Molecular formula: C19H19NO4S. Mole weight: 357.42. | |
| Parecoxib N-Oxide | An impurity of Parecoxib which is an injectable pro drug of valdecoxib and a COX2 selective inhibitor. Grades: > 95%. Molecular formula: C19H18N2O5S. Mole weight: 386.43. | |
| Parecoxib Sodium | Parecoxib Sodium (SC 69124A) is a highly selective and orally active COX-2 inhibitor, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. Parecoxib Sodium can be used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis in vivo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC 69124A. CAS No. 198470-85-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-17474A. | |
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