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| Product | Description | |
|---|---|---|
| Vandetanib | Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity ( IC 50 =40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 ( IC 50 =110 nM) and EGFR/HER1 ( IC 50 =500 nM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZD6474. CAS No. 443913-73-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10260. |  |
| Vandetanib | Vandetanib is a once-daily oral inhibitor of vascular endothelial growth factor receptor-2 and epidermal growth factor receptor kinase activity. The activity of Vandetanib plus Docetaxel was assessed in patients with previously treated non-small-cell lung cancer (NSCLC). Group: Biochemicals. Alternative Names: N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine; 4- (4-Bromo-2-fluoroanilino) -6-methoxy-7-[ (1-methylpiperidin-4-yl) methoxy]quinazoline; ZD 6474; Zactima. Grades: Highly Purified. CAS No. 443913-73-3. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C22H24BrFN4O2, Molecular Weight: 475.35. US Biological Life Sciences. |  Worldwide |
| Vandetanib | Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 with IC50 of 40 nM. Uses: Antineoplastic. Synonyms: ZD6474; ZD 6474; ZD-6474; 4-Quinazolinamine, N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-; N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine; 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline; AZD 6474; AZD-6474; AZD6474; Caprelsa; CH 331; N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-(N-methylpiperidin-4-ylmethoxy)quinazolin-4-amine; Zactima. Grades: >98%. CAS No. 443913-73-3. Molecular formula: C22H24BrFN4O2. Mole weight: 475.35. |  |
| Vandetanib hydrochloride | Vandetanib hydrochloride is an anti-cancer drug that is used for the treatment of certain tumours of thethyroid gland. It acts as a kinase inhibitor of a number of cell receptors, mainly the vascular endothelial growth factor receptor (VEGFR), the epidermal growth factor receptor (EGFR), and the RET-tyrosine kinase. Synonyms: Zactima hydrochloride; ZD6474 hydrochloride; ZD 6474 hydrochloride; ZD-6474 hydrochloride. Grades: >98%. CAS No. 524722-52-9. Molecular formula: C22H25BrClFN4O2. Mole weight: 511.81. | |
| Vandetanib hydrochloride | Vandetanib hydrochloride. Uses: For analytical and research use. Group: Impurity standards. CAS No. 524722-52-9. Molecular Formula: C22H25BrClFN4O2. Mole Weight: 511.82. Catalog: APB524722529. |  |
| Vandetanib Impurity 2 | Vandetanib Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 910298-60-1. Molecular Formula: C21H22BrFN4O2. Mole Weight: 461.34. Catalog: APB910298601. | |
| Vandetanib Impurity 3 | Vandetanib Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 910298-61-2. Molecular Formula: C22H24BrFN4O3. Mole Weight: 491.36. Catalog: APB910298612. | |
| Vandetanib Impurity 4 | Vandetanib Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1797030-22-8. Molecular Formula: C22H24BrFN4O3. Mole Weight: 491.36. Catalog: APB1797030228. | |
| Vandetanib Impurity 5 | Vandetanib Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 264208-69-7. Molecular Formula: C16H21N3O3. Mole Weight: 303.36. Catalog: APB264208697. | |
| Vandetanib Impurity 6 | Vandetanib Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1346598-62-6. Molecular Formula: C22H20D4BrFN4O3. Mole Weight: 495.39. Catalog: APB1346598626. | |
| Vandetanib Impurity I | Vandetanib Impurity I. Uses: For analytical and research use. Group: Impurity standards. CAS No. 338992-12-4. Molecular Formula: C21H22BrFN4O2. Mole Weight: 461.34. Catalog: APB338992124. | |
| Vandetanib N-Oxide | Vandetanib N-Oxide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C22H24BrFN4O3, Molecular Weight: 491.35. US Biological Life Sciences. | Worldwide |
| Vandetanib trifluoroacetate | Vandetanib is an anti-cancer drug that is used for the treatment of certain tumours of thethyroid gland. It acts as a kinase inhibitor of a number of cell receptors, mainly the vascular endothelial growth factor receptor (VEGFR), the epidermal growth factor receptor (EGFR), and the RET-tyrosine kinase. Synonyms: Zactima trifluoroacetate; ZD6474 trifluoroacetate; ZD-6474 trifluoroacetate; ZD 6474 trifluoroacetate. Grades: >98%. CAS No. 338992-53-3. Molecular formula: C24H25BrF4N4O4. Mole weight: 589.38. | |
| Hydroxy vandetanib | Hydroxy vandetanib. Group: Biochemicals. Alternative Names: 4- [ [ [4- [ (4-Bromo-2-fluorophenyl) amino] -6-methoxy-7-quinazolinyl] oxy] methyl] -1-piperidinemethanol. Grades: Highly Purified. CAS No. 910298-61-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C22H24BrFN4O3. US Biological Life Sciences. | Worldwide |
| N-Demethyl vandetanib | N-Demethyl vandetanib. Group: Biochemicals. Alternative Names: N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-(4-piperidinylmethoxy)-4-quinazolinamine; 4- (4-Bromo-2-fluoroanilino) -6-methoxy-7-[ (piperidin-4-yl) methoxy]quinazoline. Grades: Highly Purified. CAS No. 338992-12-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C21H22BrFN4O2. US Biological Life Sciences. | Worldwide |
| N-Desmethyl Vandetanib | N-Desmethyl Vandetanib is a metabolite of Vandetanib. Vandetanib is an antitumor drug used for the treatment of medullary thyroid cancer. Vandetanib effects through inhibiting vascular endothelial growth factor receptor-2 (VEGFR), epidermal growth factor receptor (EGFR) and the RET-tyrosine kinase activity. Synonyms: N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-(4-piperidinylmethoxy)-4-quinazolinamine; 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(piperidin-4-yl)methoxy]quinazoline. CAS No. 338992-12-4. Molecular formula: C21H22BrFN4O2. Mole weight: 461.34. | |
| O-Demethyl Vandetanib | A metabolite of Vandetanib. Group: Biochemicals. Alternative Names: 4-[(4-Bromo-2-fluorophenyl)amino]-7-[(1-methyl-4-piperidinyl)methoxy]-6-quinazolinol. Grades: Highly Purified. CAS No. 910298-60-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| O-Desmethyl Vandetanib | O-Desmethyl Vandetanib is a metabolite of Vandetanib. Vandetanib is an antitumor drug used for the treatment of medullary thyroid cancer. Vandetanib effects through inhibiting vascular endothelial growth factor receptor-2 (VEGFR), epidermal growth factor receptor (EGFR) and the RET-tyrosine kinase activity. Synonyms: 4-[(4-Bromo-2-fluorophenyl)amino]-7-[(1-methyl-4-piperidinyl)methoxy]-6-quinazolinol. CAS No. 910298-60-1. Molecular formula: C21H22BrFN4O2. Mole weight: 461.34. | |
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