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Vicenistatin It is a macrocyclic lipid antibiotic produced by the strain of Str. sp. HC34. In vitro it is cytotoxic to human leukemia HL-60 cells and human colon cancer Co-LO205 cells with IC50 (μg/mL) of 0.12 and 0.19, respectively. Synonyms: Azacycloeicosa-3,5,10,13,15-pentaen-2-one, 7,11,13,19-tetramethyl-8-[[2,4,6-trideoxy-4-(methylamino)-β-D-ribo-hexopyranosyl]oxy]-, (3E,5E,7S,8S,10E,13E,15E,19S)-; Antibiotic HC34; NSC 641691; Vicenistatine. CAS No. 150999-05-6. Molecular formula: C30H48N2O4. Mole weight: 500.71. BOC Sciences 5
Vicenistatin M It is produced by the strain of Streptomyces sp. HC-34. It is a homologue of Mycarose replacing amino sugars in the Vicenstatin molecule, and it loses the cytotoxicity of Vicenstatin. Synonyms: (6S,7S,18S)-20-aza-6,10,12,18-tetramethyl-7-O-(2',6'-dideoxy-3'-C-methyl-β-D-ribo-hexopyranosyl)-cycloicosa-2,4,9,12,14-pentaen-1-one; (3E,5E,10E,13E,15E)-(7S,8S,19S)-8-((2R,4S,5R,6R)-4,5-Dihydroxy-4,6-dimethyl-tetrahydro-pyran-2-yloxy)-7,11,13,19-tetramethyl-azacycloicosa-3,5,10,13,15-pentaen-2-one; Vicenistatine M. CAS No. 312532-50-6. Molecular formula: C30H47NO5. Mole weight: 501.70. BOC Sciences 6

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