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| Product | Description | |
|---|---|---|
| Virginiamycin | Virginiamycin complex contains two streptogramin antibiotics, virginiamycin M1 (75%) and virginiamycin S1 (25%). It is an antibiotic used primarily in the treatment of staphylococcal infections, and to a less extent streptococcal infections. Uses: Anti-bacterial agents. Synonyms: Pristinamycin. CAS No. 11006-76-1. Molecular formula: C71H84N10O17. Mole weight: 1349.48. |  |
| Virginiamycin | Virginiamycin. Uses: For analytical and research use. Group: Pharma & vet compounds & metabolites; pharma & vet compounds & metabolites; chiral molecules. Alternative Names: Pyostacin, Stafac, Eskalin 500, Streptogramin, Stafac 500, Livelong, Eskalin V,Mikamycin, Stafac 20, Stapyocine, Virgimycin, Pyostacine, Lactrol. CAS No. 11006-76-1. Molecular Formula: C43H49N7O10+C28H35N3O7. Mole Weight: 1349.51. Catalog: APS11006761. SMILES: CCC1C (=O) N2CCCC2C (=O) N (C (C (=O) N3CCC (=O) CC3C (=O) NC (C (=O) OC (C (C (=O) N1) NC (=O) C4=C (C=CC=N4) O) C) C5=CC=CC=C5) CC6=CC=CC=C6) C. CC1C=CC (=O) NCC=CC (=CC (CC (=O) CC2=NC (=CO2) C (=O) N3CCC=C3C (=O) OC1C (C) C) O) C. Format: Neat. |  |
| Virginiamycin B | Pristinamycin IA is an ester peptide antibiotic produced by Str. pristinaespiralis 5647 (NRRL 2958). Activity against gram-positive bacteria. Synonyms: Ostreogrycin B, Pristinamycin IA, Streptogramin B, Syncothrecin B1, Synergistin B, Vernamycin Balpha, Virginiamycin 1A, NSC 125176, 14725-1, PA 114B, RP 12535. Grades: ≥ 95%. CAS No. 3131-3-1. Molecular formula: C45H54N8O10. Mole weight: 866.96. | |
| Virginiamycin B | Virginiamycin B is a depsipeptide antibiotic co-produced with ostreogrycin A and used as a synergistic mixture. Virginiamycin B, also known as ostreogrycin B and streptogramin B among other synonyms, was discovered independently and named by several groups leading to considerable confusion in the literature. Viriginiamycin B acts as a synergist binding to the conformational change in the peptidyl transferase centre of the 50S ribosome induced by ostreogrycin A. Group: Biochemicals. Grades: Highly Purified. CAS No. 3131-3-1. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Virginiamycin Complex | Virginiamycin complex is defined as a mixture of 75% virginamycin M1 (ostreogrycin A) and 25% virginiamycin S1 and the less abundant S analogs. As the two major components have quite different solubilities these proportions are not readily achieved or used. The individual components are isolated and re-combined to provide the defined components of virginiamycin complex. The structure composition of the complex is important as Virginiamycin S1 acts a synergist, binding to the conformational change of the peptidyl transferase center of the 50S ribosome induced by ostreogrycin A. Group: Biochemicals. Alternative Names: Cebin V, Eskalin V, Eskamicin, Stafac, Stephylomycin, Mikamycin, Ostreogrycin, Patricin, Pristinamycin, Streptogramin, Vernamycin. Grades: Highly Purified. CAS No. 11006-76-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Virginiamycin M1 | Macrolactone antibiotic. Antibacterial; growth promotant. Group: Biochemicals. Grades: Highly Purified. CAS No. 21411-53-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Virginiamycin M1 | Virginiamycin M1 (Pristinamycin IIA; Ostreogrycin A), produced by Streptomyces virginiae , is an polyunsaturated macrocyclic lactone antibiotic and acts as a component of Virginiamycin (HY-112665) [1]. Virginiamycin M1 alone is against Staphylococcus aureus with a MIC of 0.25 μg/mL. Uses: Scientific research. Group: Natural products. Alternative Names: Pristinamycin IIA; Ostreogrycin A. CAS No. 21411-53-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6686. |  |
| Virginiamycin M1 | Virginiamycin M1. Uses: For analytical and research use. Group: Pharma & vet compounds & metabolites; pharma & vet compounds & metabolites. Alternative Names: NSC 87432, (3R, 4R, 5E, 10E, 12E, 14S)-8, 9, 14, 15, 24, 25-Hexahydro-14-hydroxy-4, 12-dimethyl-3-(1-methylethyl)-3H-21, 18-nitrilo-1H, 22H-pyrrolo[2, 1-c][1, 8, 4, 19]dioxadiazacyclotetracosine-1, 7, 16, 22(4H, 17H)-tetrone, Factor M, RP 12536, [3R-(3R*, 4R*, 5E, 10E, 12E, 14S*)]-8, 9, 14, 15, 24, 25-Hexahydro-14-hydroxy-4, 12-dimethyl-3-(1-methylethyl)-3H-21, 18-nitrilo-1H, 22H-pyrrolo[2, 1-c][1, 8, 4, 19]dioxadiazacyclotetracosine-1, 7, 16, 22(4H, 17H)-tetrone, NSC 244426, Ostreogrycin A (7CI), PA 114A, Virginiamycin M1, Mikamycin A (6CI,8CI), Antibiotic PA 114A1, Pristinamycin IIA, 3H-21, 18-Nitrilo-1H, 22H-pyrrolo[2, 1-c][1, 8, 4, 19]dioxadiazacyclotetracosine-1, 7, 16, 22(4H, 17H)-tetrone, 8,9,14,15,24,25-hexahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-, (3R,4R,5E,10E,12E,14S)-, Staphylomycin M1, Pristinamycin II, Factor M (antibiotic), Antibiotic PA 114A, Streptogramin A, Vernamycin A. CAS No. 21411-53-0. Molecular Formula: C28H35N3O7. Mole Weight: 525.59. Catalog: APS21411530A. SMILES: CC (C)[C@H]1OC (=O)C2=CCCN2C (=O)c3coc (CC (=O)C[C@H] (O)\C=C (/C)\C=C\CNC (=O)\C=C\[C@H]1C)n3. Format: Neat. | |
| Virginiamycin S1 | It is a depsipeptide antibiotic produced by the strain of Str. virginiae and Str. virginiae var. sp. It has anti-gram-positive bacteria and mycobacterium effects, and the antibacterial activity of component M of Virginiamycin against cocci is stronger than component S, while the activity is stronger than component M. Synonyms: Staphylomycin S; Staphylomycin S1; Antibiotic 1754Z3B; Virginiamycin factor S; NSC177858; Stephylomycin; Eskamicin; Cebin V; Factor S; Glycine, N-[(3-hydroxy-2-pyridinyl)carbonyl]-L-threonyl-D-2-aminobutanoyl-L-prolyl-N-methyl-L-phenylalanyl-4-oxo-L-2-piperidinecarbonyl-L-2-phenyl-, r-lactone. Grades: >99% by HPLC. CAS No. 23152-29-6. Molecular formula: C43H49N7O10. Mole weight: 823.89. | |
| Virginiamycin S1 | Virginiamycin S1 is a main component of virginiamycin preparations. Virginiamycin S1 is one of a family of depsipeptide antibiotic co-produced with ostreogrycin A and used as a synergistic mixture. Virginiamycin S1 also known as Staphylomycin S and Factor S, among other synonyms were discovered independently and named by several groups leading to considerable confusion in the literature. Virginiamycin S1 acts a synergist binding to the conformational change induced by ostreogrycin A of the peptidyl transferase centre of the 50S ribosome. Virginiamycin S1 differs from virginiamycin B in lacking the dimethylamino moiety on the phenyl ring. Group: Biochemicals. Alternative Names: Staphylomycin S, PA 114B2, Antibiotic 899, Antibiotic PA 114B2, Antibiotic 1745Z3B, Factor S. Grades: Highly Purified. CAS No. 23152-29-6. Pack Sizes: 5mg. Molecular Formula: C43H49N7O10, Molecular Weight: 823.89. US Biological Life Sciences. | Worldwide |
| Virginiamycin S2 | It is a depsipeptide antibiotic produced by the strain of Str. virginiae and Str. virginiae var. sp. It has anti-gram-positive bacteria and mycobacterium effects, and the antibacterial activity of component M of Virginiamycin against cocci is stronger than component S, while the activity is stronger than component M. Synonyms: Staphylomycin-S2; 4-L-Phenylalanine-5-(cis-4-hydroxy-L-2-piperidinecarboxylic acid)virginiamycin S1; N-[(3-Hydroxy-2-pyridinyl)carbonyl]cyclo[L-Thr*-D-Abu-L-Pro-L-Phe-[(4R)-4-hydroxy-L-pipecoloyl]-L-phenyl-Gly-]; N-[(3-Hydroxy-2-pyridyl)carbonyl]-cyclo[L-Thr*-D-Abu-L-Pro-L-Phe-4β-hydroxy-L-Hpr-L-phenyl-Gly-]. CAS No. 33477-38-2. Molecular formula: C42H49N7O10. Mole weight: 811.88. | |
| Virginiamycin S3 | It is a depsipeptide antibiotic produced by the strain of Str. virginiae and Str. virginiae var. sp. It has anti-gram-positive bacteria and mycobacterium effects, and the antibacterial activity of component M of Virginiamycin against cocci is stronger than component S, while the activity is stronger than component M. Synonyms: Staphylomycin S3; Virginiamycin S1, 5-(5-hydroxy-4-oxo-L-2-piperidinecarboxylic acid)-; N-[(3-Hydroxy-2-pyridinyl)carbonyl]cyclo[L-Thr*-D-Abu-L-Pro-N-methyl-L-Phe-4-oxo-5-hydroxy-L-pipecoloyl-L-phenyl-Gly-]. CAS No. 33477-39-3. Molecular formula: C43H49N7O11. Mole weight: 839.89. | |
| Ostreogrycin A (Mikamycin A, Pristinamycin IIA, Stephylomycin M1, Streptogramin A, Syncothrecin A, Synergistin A1, Virginiamycin M1, Vernamycin A, Antibiotic 14752-2, Antibiotic E129A, Antibiotic PA 114A, Antibiotic 1745Z3A, Antibiotic 547C, Factor M) | Ostreogrycin A also commonly referred to as virginiamycin M1 or streptogramin A is the major component of the "virginamycin complex". In the 1950s this complex was independently discovered so many times the literature became highly confusing. Ostreogrycin A is a macrocyclic lactone antibiotic that acts syngeristically with the structurally unrelated cyclic depsipeptides more commonly known as the virginiamycins B (ostreogrycin B or streptogramin B) and S to inhibit peptide elongation. This is achieved by blocking formation of a peptide bond between the growing peptide chain (peptidyl-tRNA) linked to the 50S ribosome and aminoacyl-tRNA. Ostreogrycin A has proven to be highly active against Gram positive bacteria, particularly methicillin-resistant S. aureus. Group: Biochemicals. Alternative Names: Mikamycin A, Pristinamycin IIA, Stephylomycin M1, Streptogramin A, Syncothrecin A, Synergistin A1, Virginiamycin M1, Vernamycin A, Antibiotic 14752-2, Antibiotic E129A, Antibiotic PA 114A, Antibiotic 1745Z3A, Antibiotic 547C, Factor M. Grades: Highly Purified. CAS No. 21411-53-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Dalfopristin | A semi-synthetic analogue of ostreogrycin A (virginiamycin M, pristinamycin IIA, streptogramin A) formed by addition of diethylaminoethylthiol to the 2-pyrroline group of ostreogrycin, followed by oxidation to the sulphone. The structural changes provide a more hydrophobic compound with a readily ionisable group for generating a salt. Dalfopristin is used commercially in synergistic combination with quinupristin (70:30). There is little published data on the synthesis, biological or antibiotic activity of dalfopristin alone, however the combination product is highly effective, including activity against antibiotic resistant strains. Synonyms: Dalfopristinum. Grades: >98% by HPLC. CAS No. 112362-50-2. Molecular formula: C34H50N4O9S. Mole weight: 690.85. | |
| L-lysine cyclodeaminase | Requires bound NAD+. The enzyme produces the non-proteinogenic amino acid L-pipecolate, which is incorporated into multiple secondary metabolite products, including rapamycin, tobulysin, virginiamycin and pristinamycin. Group: Enzymes. Synonyms: rapL (gene name); fkbL (gene name); tubZ (gene name); visC (gene name). Enzyme Commission Number: EC 4.3.1.28. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5287; L-lysine cyclodeaminase; EC 4.3.1.28; rapL (gene name); fkbL (gene name); tubZ (gene name); visC (gene name). Cat No: EXWM-5287. |  |
| Ostreogrycin B3 | It is produced by the strain of Str. ostreogriseus NRRL 2558 (NCIB 8792). It has anti-gram positive bacterial activity, and Ostreogrycin A has stronger antibacterial activity than other components. Ostreogrycin A or G has synergistic antibacterial effect with each component of Ostreogrycin B. The Complex has protective effect on mice infected with bacteria by subcutaneous or oral administration. Synonyms: Virginiamycin-S1; N-(3-Hydroxypicolinoyl)-cyclo[L-Thr*-D-Abu-L-Pro-4-(dimethylamino)-N-methyl-L-Phe-4-oxo-5-hydroxy-L-Hpr-L-phenyl-Gly-]. CAS No. 31508-69-7. Molecular formula: C45H54N8O11. Mole weight: 882.96. | |
| Pristinamycin | Heterocyclic Organic Compound. Alternative Names: PRISTINAMYCIN; VIRGINIAMYCIN; antibioticno.899; eskalin500; eskalinv; mikamycin; ostreogrycin; patricin. CAS No. 11006-76-1. Molecular formula: C71H84N10O17. Mole weight: 1349.48346. Catalog: ACM11006761. |  |
| Pristinamycin | Pristinamycin is a complex of antibiotics produced by streptomyces pristinaespiralis, containing two components Pristinamycin IA and Pristinamycin IIA. Pristinamycin IA is a macrolide, and Pristinamycin IIA (streptogramin A) is a depsipeptide. Pristinamycin has been indicated for the treatment of MRSA. Synonyms: Pyostacine; Stafac; Pristinamycine; Staphylomycin; Virginiamycin. CAS No. 270076-60-3. Molecular formula: C73H89N11O17. Mole weight: 1392.55. | |
| Pristinamycin IIA | Pristinamycin IIA is an ester peptide antibiotic produced by Str. pristinaespiralis 5647 (NRRL 2958). Activity against gram-positive bacteria. Uses: Anti-bacterial agents. Synonyms: virginiamycin M1; Streptogramin A; Mikamycin A; Ostreogrycin a. Grades: ≥ 95%. CAS No. 21411-53-0. Molecular formula: C28H35N3O7. Mole weight: 525.59. | |
| Pristinamycin IIB | Pristinamycin IIB is an ester peptide antibiotic produced by Str. pristinaespiralis 5647 (NRRL 2958). Activity against gram-positive bacteria. Synonyms: Volpristin; Virginiamycin M2. CAS No. 21102-49-8. Molecular formula: C28H37N3O7. Mole weight: 527.61. | |
| Quinupristin | Heterocyclic Organic Compound. Alternative Names: 4-[4-(DiMethylaMino)-N-Methyl-L-phenylalanine]-5-[(2S,5R)-5-[[[(3S)-1-azabicyclo[2.2.2]oct-3-yl]thio]Methyl]-4-oxo-2-piperidinecarboxylic acid]virginiaMycin S1;Antibiotic RP 57669;RP 57669;RP 68888; Quinupristin(RP-57669); QuinupristinDiscontinued; Quinupristin Mesylate. CAS No. 120138-50-3. Molecular formula: C53H67N9O10S. Mole weight: 1022.23. Catalog: ACM120138503. | |
| Quinupristin | Quinupristin is an antibiotic and usually used in combination with dalfopristin (The trade name is Synercid). It is active against Gram-positive bacteria through inhibiting protein synthesis of the cells, but not active against Gram-negative bacteria, so it needs to be given in combination with other antibacterials for mixed infections which also involve Gram-negative organisms. Uses: Semisynthetic depsipeptide type i streptogramin. an antibacterial agent. Synonyms: N-((6R, 9S, 10R, 13S, 15aS, 18R, 22S, 24aS)-22-(4-(dimethylamino)benzyl)-6-ethyl-10, 23-dimethyl-5, 8, 12, 15, 17, 21, 24-heptaoxo-13-phenyl-18-((((S)-quinuclidin-3-yl)thio)methyl)docosahydro-12H-pyrido[2, 1-f]pyrrolo[2, 1-l][1]oxa[4, 7, 10, 13, 16]pentaazacyclononadecin-9-yl)-3-hydroxypicolinamide; RP68888; RP57669; Antibiotic RP 57669; 4-[4-(Dimethylamino)-N-methyl-L-phenylalanine]-5-[(2S,5R)-5-[[[(3S)-1-azabicyclo[2.2.2]oct-3-yl]thio]methyl]-4-oxo-2-piperidine carboxylic acid] Virginiamycin S1. Grades: 95%. CAS No. 120138-50-3. Molecular formula: C53H67N9O10S. Mole weight: 1022.22. | |
| Quinupristin-Dalfopristin complex | Quinupristin-dalfopristin complex is a 70:30 (w/w) complex of two semi-synthetic Streptomycin antibiotic. It is a highly effective antibiotic with activity against resistant strains. Synonyms: Synercid complex; Dalfopristin-Quinupristin complex; RP 59500; 4-[4-(dimethylamino)-N-methyl-L-phenylalanine]-5-[(2S)-5-[(1-azabicyclo[2.2.2]oct-3-ylthio)methyl]-4-oxo-2-piperidinecarboxylic acid]-virginiamycin S1 mixture with (3R, 4R, 5E, 10E, 12E, 14S, 26R, 26aS)-26-[[2-(diethylamino)ethyl]sulfonyl]-8, 9, 14, 15, 24, 25, 26, 26a-octahydro-14-hydroxy-4, 12-dimethyl-3-(1-methylethyl)-3H-21, 18-nitrilo-1H, 22H-pyrrolo[2, 1-c][1, 8, 4, 19]dioxadiazacyclotetracosine-1, 7, 16, 22(4H, 17H)-tetrone. Grades: >98% by HPLC. CAS No. 126602-89-9. Molecular formula: C53H67N9O10S.C34H50N4O9S. Mole weight: 1713.09. | |
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